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Complexity Theory : Exploring the Limits of Efficient Algorithms
Complexity theory is the theory of determining the necessary resources for the solution of algorithmic problems and, therefore, the limits of what is possible with the available resources. An understanding of these limits prevents the search for non-existing efficient algorithms. This textbook considers randomization as a key concept and emphasizes the interplay between theory and practice: New branches of complexity theory continue to arise in response to new algorithmic concepts, and its results - such as the theory of NP-completeness - have influenced the development of all areas of computer science. The topics selected have implications for concrete applications, and the significance of complexity theory for today's computer science is stressed throughout.
Clinical applications of mass spectrometry in drug analysis : Methods and protocols
This fully updated volume describes methods and protocols for a number of drugs and toxins in a stepwise manner. Exploring the versatility and flexibility of mass spectrometry, the book covers the advantages of this technology, which typically include elimination of the need for special reagents such as antibodies, increased sensitivity and specificity, and multi-component analysis enabling the screening of tens to hundreds of compounds in a single assay run. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls.
Cell cycle control : Methods and protocols
Collects techniques to study the highly regulated cell cycle process. Beginning with chapters investigating these processes and assessing how cells respond when these complicated pathways are simplified by using synthetic biology and in vitro reconstitutions, the book continues by exploring how cells sense and respond to environmental conditions, different model systems and cellular types used to visualize cellular architecture during cell division, as well as innovative single cell microscopy techniques to highlight the heterogeneity of the cell population with respect to cell cycle progression. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Cartographies of the Mind : Philosophy and Psychology in Intersection
The present book is a collection of essays exploring some classical dimensions of mind both from the perspective of an empirically-informed philosophy and from the point of view of a philosophically-informed psychology. In the last three decades, the level of interaction between philosophy and psychology has increased dramatically. As a contribution to this trend, this book explores some areas in which this interaction has been very productive – or, at least, highly provocative.
Building information modeling : BIM in current and future practice
"Thought leaders from universities and professional practice composed essays exploring BIM's potential to improve the products and processes of architectural design including the structure and content of the tools themselves. These authors provide insights for assessing the current practice and research directions of BIM and speculate about its future. Design Thinking and BIM / BIM Analytics / Comprehensive BIM / Reasoning with BIM / Professional BIM / BIM Speculations"
Building for well-being : Exploring health-focused rating systems for design and construction professionals
The first introduction to health-focused building standards for design and construction professionals. More than a summary of the state of the field, this practical resource guides designers, builders, developers, and owners through considerations for incorporating WELL®, Fitwel®, and other systems from the planning phase to ground-breaking and beyond.Drawing on the authors’ backgrounds in sustainable design and public health, chapters on the evolution of the green building movement and the relationship between health and the built environment provide vital context for understanding health-focused standards and certifications. The final chapter looks toward the future of health and the built environment.
Body and Practice in Kant
This book argues that this standard image of the great German philosopher is radically wrong. Not only does Kant reflect constantly upon the fact that human life is embodied, but the Critique of pure reason itself may be read as a critical reflection aimed at exploring some significant philosophical implications of this fact.
Biotechnology of medicinal plants with antiallergy properties : Research trends and prospects
Covers critically investigated information on medicinal plants prioritized for their anti-allergy properties. It offers insights into strategies related to the distribution, mechanism of action, and assessment of antiallergic medicinal plants, and also delves into crucial aspects of modern biotechnological tools, addressing their implementation challenges, presenting innovative approaches through case studies, and exploring opportunities for nanotechnologies. These elaborated discussions aim to raise awareness and bridge the gap between human health and the biodiversity of antiallergic medicinal plants.
Biomarkers for alzheimer’s disease drug development
Helping to accelerate Alzheimer’s disease drug development. Addressing the latest advances in preclinical and clinical research, including new insights into the molecular mechanisms and emerging therapeutic strategies, the book continues by exploring digital biomarkers and advanced neuroimaging analysis which will transform how clinical trials in the Alzheimer’s disease field are performed.
Bioethics and the Holocaust : A Comprehensive Study in How the Holocaust Continues to Shape the Ethics of Health, Medicine and Human Rights
This book offers a framework for understanding how the Holocaust has shaped and continues to shape medical ethics, health policy, and questions related to human rights around the world. The field of bioethics continues to face questions of social and medical controversy that have their roots in the lessons of the Holocaust, such as debates over beginning-of-life and medical genetics, end-of-life matters such as medical aid in dying, the development of ethical codes and regulations to guide human subject research, and human rights abuses in vulnerable populations. As the only example of medically sanctioned genocide in history, and one that used medicine and science to fundamentally undermine human dignity and the moral foundation of society, the Holocaust provides an invaluable framework for exploring current issues in bioethics and society today. This book, therefore, is of great value to all current and future ethicists, medical practitioners and policymakers – as well as laypeople.
Bioceramics in endodontics
Focuses on overall makeup of dental bioceramics and relevant clinical situations in endodontics. Blends together detailed information on the physico-chemical and biological properties of bioceramics with their clinical application in endodontics, exploring history and chemistry, mechanical properties, advantages of bioceramics over other materials, and clinical cases with high definition pictures and videos demonstrating their usage across wide variety of clinical situations in endodontics.
Big Data in Context : Legal, Social and Technological Insights
Sheds new light on a selection of big data scenarios from an interdisciplinary perspective. It features legal, sociological and economic approaches to fundamental big data topics such as privacy, data quality and the ECJ’s Safe Harbor decision on the one hand, and practical applications such as smart cars, wearables and web tracking on the other. Addressing the interests of researchers and practitioners alike, it provides a comprehensive overview of and introduction to the emerging challenges regarding big data.All contributions are based on papers submitted in connection with ABIDA (Assessing Big Data), an interdisciplinary research project exploring the societal aspects of big data and funded by the German Federal Ministry of Education and Research.
Average-Cost Control of Stochastic Manufacturing Systems
This book is concerned with hierarchical control of manufacturing systems under uncertainty. It focuses on system performance measured in long-run average cost criteria, exploring the relationship between control problems with a discounted cost and that with a long-run average cost in connection with hierarchical control. A new theory is articulated that shows that hierarchical decision making in the context of a goal-seeking manufacturing system can lead to a near optimization of its objective. The approach in the book considers manufacturing systems in which events occur at different time scales.
Artificiality and sustainability in entrepreneurship : Exploring the unforeseen, and paving the way to a sustainable future
Explores the past, present, and future of artificiality and sustainability in entrepreneurship – the unforeseen consequences and ways to advance to a sustainable future. In particular, it connects artificiality, sustainability and entrepreneurship, intertwining artificial with the specific phenomenon of those novel digital technologies that provoke continuous and significant change in our lives and business. Unlike digital entrepreneurship research, which focuses on digital technology development and management, this book covers processes and mechanisms of sustainable adaptability of entrepreneurs, the business logic of start-ups, and the collaborative behaviours under the mass digital transformation, including the prevalence of artificial intelligence. Some of the questions that this book answers are as follows: How has entrepreneurship reacted to such challenges previously? What lessons have been learned and need to be carried forward? How can entrepreneurship and the artefacts of entrepreneurship respond to current challenges? What should be the mindset of the entrepreneur to assure sustainable adaptation? How to embrace and embed the new business logic?
Argumentation in Science Education : Perspectives from Classroom-Based Research
This book brings together the work of leading experts in argumentation in science education. It presents research combining theoretical and empirical perspectives relevant for secondary science classrooms. Since the 1990s, argumentation studies have increased at a rapid pace, from stray papers to a wealth of research exploring ever more sophisticated issues. This volume constitutes a unique collection and covers fundamental issues in argumentation such as cognitive, methodological and epistemological aspects; classroom-based research in teaching and learning of argumentation in science classrooms; and argumentation in context such as in socio-scientific and moral contexts. The book’s underlying premise is that argumentation is a significant aspect of scientific inquiry and plays an important role in teaching and learning of science.
Architecture in context : Designing in the Middle East
Provides a foundation for understanding the critical context of architecture and design in this region. It does this by: presenting a practical overview of architectural know-how in the Middle East, and its potential for cultivating a sense of place introducing local architectural vocabularies and styles, and how they can still be reactivated in contemporary design exploring the cultural and contextual meaning of forms as references that may influence contemporary architecture discussing important discourses and trends in architecture that allow a rethinking of the current global/local dichotomy.
Applied geotechnics for construction projects ; Vol. 1 : Soil and Experimental Data
Applied Geotechnics for Construction Projects 1 first defines, identifies and classifies soils, exploring their complexities and weaknesses, and then outlines the basic principles of stresses and strains that establish and develop within soils. The third chapter of the book introduces and develops methods of soil investigation in order to experimentally determine the geotechnical parameters that are useful in the design stage of construction projects.
Anticancer activity in heterocyclic organic structures : A pathway to novel drug development : Part 1
New Directions in Organic & Biological Chemistry, explores the development of cancer therapeutics, focusing on molecular chemistry and advanced drug design approaches. Written by experts in theoretical chemistry and molecular chemistry, they bridge the gap between theoretical chemistry, molecular biology, and drug development. In Part I, they focus on the fundamental properties of heterocyclic compounds and innovative methodologies being employed to enhance therapeutic potential. By exploring various classes of heterocyclic compounds and diverse anticancer mechanisms.
Animating Unpredictable Effects : Nonlinearity in Hollywood’s R&D Complex
Uncanny computer-generated animations of splashing waves, billowing smoke clouds, and characters’ flowing hair have become a ubiquitous presence on screens of all types since the 1980s. This Open Access book charts the history of these digital moving images and the software tools that make them. Unpredictable Visual Effects uncovers an institutional and industrial history that saw media industries conducting more private R&D as Cold War federal funding began to wane in the late 1980s. In this context studios and media software companies took concepts used for studying and managing unpredictable systems like markets, weather, and fluids and turned them into tools for animation. Unpredictable Visual Effects theorizes how these animations are part of a paradigm of control evident across society, while at the same time exploring what they can teach us about the relationship between making and knowing.
An Invitation to Abstract Mathematics
this book begins with a playful exploration of the building blocks of mathematics, such as definitions, axioms, and proofs. A study of the fundamental concepts of logic, sets, and functions follows, before focus turns to methods of proof. Having covered the core of a transition course, the author goes on to present a selection of advanced topics that offer opportunities for extension or further study. Throughout, appendices touch on historical perspectives, current trends, and open questions, showing mathematics as a vibrant and dynamic human enterprise.This second edition has been reorganized to better reflect the layout and curriculum of standard transition courses. It also features recent developments and improved appendices. An Invitation to Abstract Mathematics is ideal for those seeking a challenging and engaging transition to advanced mathematics, and will appeal to both undergraduates majoring in mathematics, as well as non-math majors interested in exploring higher-level concepts.
