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Difficult Decisions in Thoracic Surgery : An Evidence-Based Approach
Brief chapters are devoted to a specific question or decision in general thoracic surgery that is difficult or controversial. Although some of the content may be available in major thoracic texts, rarely are such questions posed specifically and analyzed according to the level of supporting evidence available. This book is unique in aiming to address the issues in the most clear and informed manner possible; the chapters contain both evidence-based recommendations and descriptions of surgeons’ personal practices based on their experience and the published literature. Chapters are organized around clearly identified recommendations. This provides uniformity to the presentations, making possible the identification of useful material at a glance. A general introduction describes evidence-based data and their use, decision analytic models, and how both physicians and patients make decisions currently. Over 50 different topics are then presented, including a review of available evidence and a general discussion of recommended practice.
Development and In-vitro Dissolution Test of Pilocarpine PVA : Hydrogel Lenses
Due to high water content of hydrogel (wetting) and due to extended drug release comparing to ophthalmic solution and higher transparency comparing to ophthalmic ointment, soft contact lenses were found to elongate contact time with the eye and use it for long time without causing hypoxia or needing multiple dosing per a day. The objective of the study was to design, fabricate, and investigate the effectiveness of PVA hydrogel with DMSO soft contact lens in releasing the model drug, pilocarpine.
Developing Organogel of CoEnzyme Q10
Coenzyme Q10 is a small lipophilic molecule composed of a benzoquinone ring and a hydrophobic isoprenoid tail and is present in all cell membranes. It is also an antioxidant. It plays a substantial role in energy production by acting as a mobile electron carrier in the electron transport chain. It has poor intestinal absorption and is prepared in topical forms. Organogel is a non-crystalline, non-glassy thermoreversible (thermoplastic) solid material and viscoelastic system can be regarded as a semi-solid preparation which has an immobilized external apolar phase, it is compatible with high molecular weight ingredients. The objective of present work is to prepare new dosage form with studying of different factors and conditions affecting preparation. Materials and methods: stearic acid and Flaxseed oil organogel was prepared by three methods and confirmed by quality assessment methods including: transparency, structure analysis, inverted tube test, kinetic of organogalation and stability test.
Current Advances in Drug Delivery Through Fast Dissolving
Presents detailed information about FDDFs (Fast Dissolving/Disintegrating Dosage Forms) from their inception to recent developments. Readers will learn about the technical details of various FDDF manufacturing methods, formulation aspects, evaluation and methods to conduct clinical studies. The authors also give examples of marketed fast disintegrating/dissolving drug products in US, Europe, Japan, and India. This reference is ideal for pharmacology students at all levels seeking information about this specific form of drug delivery and formulation.
Cured II - LENT Cancer Survivorship Research and Education : Late Effects on Normal Tissues
Multimodal treatment lies at the heart of the improvement in cancer cure rates. However, the more aggressive the treatment delivery in terms of dose, time and volume for radiation and chemotherapy, the more adverse effects in normal tissues can be anticipated. Against this background, a major paradigm shift has taken place in that there is a new focus on cancer survivorship. Put another way, there has been a realization that prolongation of life must be accompanied by maintenance of the quality of life: the life worth saving must be worth living.
Cryptology and network security ; Vol.4301 ; 5th International Conference, CANS 2006, Suzhou, China, December 8-10, 2006, Proceedings
This book constitutes the refereed proceedings of the 5th International Conference on Cryptology and Network Security, CANS 2006, held in Suzhou, China in December 2006. The 26 revised full papers presented together with 2 invited papers were carefully reviewed and selected from 148 submissions.
Cryptology and Network Security ; 7th International Conference, CANS 2008, Hong-Kong, China, December 2-4, 2008. Proceedings
This book constitutes the refereed proceedings of the 7th International Conference on Cryptology and Network Security, CANS 2008, held in Hong-Kong, China, in December 2008.
Cryptology and Network Security ; 6th International Conference, CANS 2007, Singapore, December 8-10, 2007, Proceedings
This book presented signatures, network security, secure keyword search and private information retrieval, public key encryption, intrusion detection, email security, denial of service attacks, and authentication.
Coupled Models for the Hydrological Cycle : Integrating Atmosphere, Biosphere and Pedosphere
Hydrologists, climatologists, soil scientists and environmental engineers are frequently asked to analyse complex environmental problems. It is becoming increasingly apparent that these problems usually involve feedbacks between atmospheric, ecological, and hydrological systems, as well as human society. It is often the feedbacks between systems that are of greatest interest because they may produce unanticipated responses. That is why coupling of different compartments of the Earth system has emerged as a general challenge to the modelling community. This book considers an array of state-of-the-art coupling and modelling concepts. First the relevant Earth system cycles are presented, followed by a discussion on scale issues and multiple equilibria. Inter- and intra-compartmental coupling is addressed, along with a debate on non-linearities and questions of parameterisation. Several applications are presented, where a focus is on cases where the hydrological cycle plays a central role.
Computed Tomography : From Photon Statistics to Modern Cone-Beam CT
Tis book provides an overview of X-ray technology, the historic developmental milestones of modern CT systems, and gives a comprehensive insight into the main reconstruction methods used in computed tomography.
Coloproctology
Coloproctology presents the state-of-the-art in coloproctology. All chapters give a comprehensive overview of etiology, incidence, epidemiology, diagnostics, medical and surgical treatment, complications and individual special considerations.
CO-ENZYME Q10
Coenzyme Q10 (CoQ10) is a fat-soluble compound that is synthesized by the body and can be obtained from the diet. Co-Q10 plays a central role in mitochondrial oxidative phosphorylation and the production of adenosine triphosphate (ATP). It also functions as an antioxidant in cell membranes and lipoproteins. Endogenous synthesis and dietary intake provide sufficient C0- Q10 to prevent deficiency in healthy people, although coenzyme Q10 concentrations in tissues decline with age. Oral supplementation of coenzyme Q10 increases coenzyme Q10 concentrations in plasma and lipoproteins. Oral high-dose co- Q10 is usually effective to treat mitochondrial disorders that are caused by mutations in coenzyme Q10 biosynthetic genes.
Materials for medical applications : Principles and practices
Discusses advanced knowledge about the synthesis and application of materials in the medical field for diagnostic and therapeutic conditions. These materials have been extensively used in various biological and medical applications, especially in drug delivery, tumor screening, bioimaging, diagnosis, and therapies. Materials for Medical Applications provides comprehensive but concise information about materials and their medical applications. The readers will get information about the trends in materials and their medical applications, as well as current material-based products that are used in the medical field. The book also discusses how materials are tested in research laboratories, preclinical (animal) trials, and clinical (human) trials, and how material-based products go through various regulatory and safety phases before reaching patients. It also discusses topics such as materials delivery, imaging, and treatments for various diseases. It includes a chapter dedicated to regulatory guidelines and policies in the application of nanomaterials and will include current clinical trial information on the materials. Finally, the book has topics such as health safety, toxicity, dosages, and long-term implications of materials.
Manual Endourology : Training for Residents
Endourology Step by Step. This manual is intended to help residents in urology learn the basic techniques of endourology. All authors are experts in this field and experienced teachers. Each chapter includes: indications, limits, risks and contraindications, a step-by-step procedure. The book is completed by extensive illustrations. Learning the basics of this fascinating technique was never so easy!
Managing Failed Anti-Reflux Therapy
This multiauthored text provides information on the pathophysiology of GERD, appropriate medical management, and proper indications for and performance of surgical and endoscopic procedures for GERD. Thousands of patients will experience inadequate relief from medical therapy or will develop complications from their procedures or recurrent or new symptoms afterwards; this text describes in detail the proper evaluation and management of such patients.
Managing diabetic wounds : Strategies for effective treatment
Delves into diabetes itself, covering its definition, various types (Type 1, Type 2, and gestational diabetes), and diagnostic laboratory findings such as blood glucose levels and HbA1c. The concept of diabetic foot is thoroughly explored, including its definition, primary causes such as neuropathy, ischemia, and infection, and crucial aspects of prevention, caution, and risk factors like poor glycemic control and smoking.
Malignant Mesothelioma : Pathogenesis, Diagnosis, and Translational Therapies
(Review from JAMA) Malignant mesothelioma is an uncommon neoplasm usually associated with exposure to asbestos. Because of its low incidence, thorough reviews of the topic are hard to find. Harvey Pass and colleagues have edited an up-to-date, comprehensive book that includes a wide range of information, from a historical perspective to descriptions of the latest treatment. The authors . . . have written chapters on the carcinogenesis, molecular genetics, and clinical aspects of mesothelioma. Malignant Mesothelioma is suitable for a broad audience. Laboratory researchers will use it as a resource for information about the pathogenesis, animal models, molecular genetics, and cell lines of mesothelioma. . . . Clinicians will benefit from this complete guide to the presentation, prognosis, imaging, and treatment of the disease. I highly recommend this book to all who are interested in mesothelioma.
Low-Dose Radiation Effects on Animals and Ecosystems : Long-Term Study on the Fukushima Nuclear Accident
Brings together the works of radiation biologists and ecologists to provide reliable radioecology data and gives insight into future radioprotection. The book examines the environmental pollution and radiation exposure, and contains valuable data from abandoned livestock in the ex-evacuation zone and from wild animals including invertebrates and vertebrates, aqueous and terrestrial animals, and plants that are subjected to long-term exposure in the area still affected by radiation. It also analyzes dose evaluation, and offers new perspectives gained from the accident, as well as an overview for future studies to promote radioprotection of humans and the ecosystem.
Local anesthesia for the dental hygienist
Provides complete instructions for the safe and effective administration of local anesthesia. Written by noted dental hygiene educator Demetra Logothetis, the first edition won a 2012 PROSE Honorable Mention award. This edition adds a new chapter on children and adolescent patients, plus new coverage of anesthetic agents and advanced techniques.
Liver and Biliary Tract Surgery : Embryological Anatomy to 3D-Imaging and Transplant Innovations
The book also covers cutting-edge research and technological advances that will shape the surgery of tomorrow. There is little doubt that technological advances in preoperative imaging, such as 3-D reconstruction, preoperative preparation with portal vein embolisation and operative techniques using bloodless RF resection methods, are already changing the nature of liver surgery.
