Page 6
Page 6
Cancer drug safety and public health policy : A changing landscape
Description and analysis of recent developments and current trends in health policy with regard to cancer drug safety. Opens with an overview of pharmacovigilance for cancer blockbuster drugs, covering both general considerations and efforts to develop a structured framework for the identification and reporting of adverse drug reactions (ADRs). A number of important examples of serious ADRs to hematology and oncology drugs are then reviewed, with evaluation of the lessons learned and the policy implications of the ensuing legal cases and their settlements. Further, the difficulty of reporting such blockbuster side effects in the medical literature is explored in an empirical study. Significant advances have been achieved in analytic methods for the identification of ADRs, and here there is a particular focus on the value of optimal discriminant analysis. Finally, the impacts on pharmacovigilance and drug safety of the huge fines paid under the U.S. False Claims Act relating to the defrauding of governmental programs also receive careful attention – these fines are playing an important role in changing the landscape for pharmaceutical safety.
Burket's oral medicine, 13th ed.
"Detailed discussions on: orofacial pain, temporomandibular disorders, headache and salivary gland disease / oral and oropharyngeal cancers, including the management of oral complications of cancer therapy / genetics, laboratory medicine and transplantation medicine pediatric and geriatric oral medicine / psychiatry and psychology / clinical research / and interpreting the biomedical literature"
Bronchial Asthma : A Guide for Practical Understanding and Treatment
Hailed by professional journals and esteemed by primary care doctors everywhere, Bronchial Asthma: A Guide for Practical Understanding and Treatment has been fully updated to help physicians face the challenge of diagnosis and the management of asthma in every variety of patient subpopulation.
Brodmann's : Localisation in the Cerebral Cortex
It is one of the major "classics" of the neurological world. Even today it forms the basis for so-called "localisation" of function in the cerebral cortex. Brodmann's "areas" are still used to designate functional regions in the cortex, the part of the brain that brings the world that surrounds us into consciousness, and which governs our responses to the world. For example, we use "area 4" for the "motor" cortex, with which we control our muscles, "area 17" for "visual" cortex, with which we see, and so on. This nomenclature is used by neurologists and neurosurgeons in the human context, as well as by experimentalists in various animals. Indeed, Brodmann's famous "maps" of the cerebral cortex of humans, monkeys and other mammals must be among the most commonly reproduced figures in neurobiological publishing. The most famous of all is that of the human brain. There can be few textbooks of neurology, neurophysiology or neuroanatomy in which Brodmann is not cited, and his concepts pervade most research publications on systematic neurobiology.
Brain and Heart Dynamics
Despite the increasing awareness that neural mechanisms are the primary cause of cardiac disease and its progression, therapy continues to focus on end-organ protection and does not approach the neural core of the problem. Growing public health problems such as heart failure are still treated with autonomic drugs that are 30-40 years old and simply act on cardiac receptors. However, it has now been shown that the progression of ischemic heart disease to heart failure is mainly due to abnormal central responses to incipient cardiac disease, with neural activation the primary cause rather than the consequence of cardiac remodeling.
Bacterial virulence factors and Rho GTPases
The authors of this volume present the synthesis on how the various host cellular Rho GTPases activities are manipulated by bacteria to fulfill their virulence.
Bacterial Biofilms
This volume tends to focus on the biology of biofilms that affect human disease. It opens with chapters that provide the reader with current perspectives on biofilm development, physiology, environmental and regulatory effects, the role of quorum sensing, and resistance/phenotypic persistence to antimicrobial agents during biofilm growth. The next chapters are devoted to common problematic biofilms, those that colonize venous and urinary catheters. The final series of chapters examines biofilm formation by four species that are important pathogens and well studied models, one of which, Yersinia pestis, cleverly adopts a biofilm state of growth within its insect vector to promote disease transmission to mammalian hosts.
Bacterial and Bacteriophage Genetics
Genetic investigations and manipulations of bacteria and bacteriophage have made vital contributions to our basic understanding of living cells and to the development of molecular biology and biotechnology. This volume is a survey of the genetics of bacteria and their viruses, and it provides students with a comprehensive introduction to this rapidly changing subject. The book is written for upper level undergraduates and beginning graduate students, particularly those who have had an introductory genetics course.
Autistic community and the neurodiversity movement : Stories from the frontline
This book marks the first historical overview of the autism rights branch of the neurodiversity movement, describing the activities and rationales of key leaders in their own words since it organized into a unique community in 1992. Sandwiched by editorial chapters that include critical analysis, the book contains 19 chapters by 21 authors about the forming of the autistic community and neurodiversity movement, progress in their influence on the broader autism community and field, and their possible threshold of the advocacy establishment
Atlas of mandibular and maxillary reconstruction with the fibula flap : A step-by-step approach
Deals with the standard technique used for reconstructing the mandible and the maxilla - the fibula flap. The reader will find useful information on all issues that are important in the surgical procedure, including the use of CAD-CAM technology (Computer Assisted Technology), bone synthesis and flap modelling. The editors draw on their 30 years of experience to provide a step-by-step description of this surgical procedure. With the help of numerous illustrations, the reader will learn the technical, functional and aesthetic developments since 1989 when this technique was first described.
Assessing Quality in European Higher Education Institutions : Dissemination, Methods and Procedures
This book collects the evaluation and accreditation experiences gathered by higher education institutions in Finland, France, Germany, Italy, the Netherlands, Portugal, the United Kingdom and Sweden.
Artistic cartography and design explorations towards the pluriverse
Explores the pluriverse of art and design through epistemological and methodological considerations. What kinds of sustainable ways are there for knowledge transfer, supporting plural agendas, finding novel ways for unsettling conversations, unlearning and learning and challenging power structures with marginalised groups and contexts through art and design? The main themes of the book are art and design methods, epistemologies and practices that provide critical, interdisciplinary, pluriversal and decolonial considerations. The book challenges the domination of the white logic of art and design and shifts away from the Anglo-European one-world system towards the pluriverse.
Arabic talking heads
The need for someone to talk to about what is going on inside us while ensuring privacy has become a necessary requirement, especially since some people in our Arab societies judge people who visit a psychiatrist as mentally ill. Therefore, in this project, we propose a solution to the previous problem, where an Arabic-speaking robot, through an interactive chat application can mitigate the psychological and negative effects that humans are exposed to in various cases.
Applications of Time Delay Systems
This book provides an update of the latest research in control of time delay systems and applications by world leading experts. It will appeal to engineers, researchers and students in Control.
Anxiety disorders : A pocket guide for primary care
In Anxiety Disorders: A Pocket Guide for Primary Care, distinguished clinicians combine over a century of experience into concise, practical information and techniques for the diagnosis, evaluation, and effective management of psychiatric disorders.
Antidepressants Beyond Depression, and Into Bacteria
Antidepressants are one of the most predominant drug groups in the pharmaceutical world, primary care units and the general public. Their original use was majorly for the treatment of depression along with other mental disorders. Today, antidepressant consume over 20% of the medical prescriptions and healthcare plans due to their recently discovered applications outside the psychiatry field. Due to the alarming rise of antibiotic resistance and the slow pace of new drug discovery, the world has been searching frantically for new or alternative drugs with antibacterial activity. Repurposing already FDA- approved drugs for uses that are off-label has become an important preposition in the pharmacy world due to its availability, low risk and low cost.
Alzheimer : 100 Years and Beyond
Few medical or scientific addresses have so unmistakeably made history as the presentation delivered by Alois Alzheimer on November 4th, 1906 in Tübingen. The celebratory event, "Alzheimer 100 Years and Beyond" organized on the initiative of the Alzheimer community in Germany and worldwide, in collaboration with the Fondation Ipsen, at the very site of the original lecture, namely the Institute of Psychiatry at the University of Tübingen in Germany from November 2nd to 5th, 2006, was the highlight of the Alzheimer Year. Over the last century of Alzheimer research (1906-2006), remarkable progress has been achieved. Most of the authors of the major discoveries and the people involved in research in this field will present, during the meeting and in this volume, the pioneering research explaining the conditions under which they were conducted. The goal of this book is to honor the work accomplished, to summarize the most important knowledge and to provide material for the history of science.
AI in clinical practice : A guide to artificial intelligence and digital medicine
Explains how artificial intelligence is applied to medicine, illustrating not only its enormous potential but also ancillary issues and the limits and risks inherent in its use on a large scale. The book focuses on the intersection between medicine and AI and its implications on the impact of human health care delivery. Topics discussed include wearable devices, health data, Internet of Things, virtual reality, robotic assistance system, and digital intelligence in the health sector. Additionally, sections discuss diagnostics and decision-making systems and machine/deep learning in clinical setting.
Agent Technology and e-Health
Multi-agent systems are one of the most exciting research areas in Artificial Intelligence. This book reports on the results achieved in this area, discusses the benefits (and drawbacks) that agent-based systems may bring to medical domains and society.
Advances in computer science - ASIAN 2004 : Higher level decision making ; 9th Asian computing ccience conference ; Dedicated to Jean-Louis Lassez on the occasion of his 5th cycle birthday, Chiang Mai, Thailand, December 8-10, 2004
Constitutes the proceedings of the 9th Asian Computing Science Conference was held in Chiang Mai in Decem-ber 2004. This volume contains papers that were presented at that conference. Its theme was “higher-level decision-making”.Philippe Flajolet was invited to give the opening keynote address, whileYuzuru Tanaka and Phillip Rogaway werealso keynote speakers. In additionto the keynote speakers, distinguished colleagues of Jean-Louis Lassez were in-vited to present talks in his honour. Many of those talks are represented bypapers in this volume, this book Include Topics : Theory of Computation / Artificial Intelligence / Software Engineering / Programming and Operating Systems / Cryptology / Discrete Mathematics in Computer Science / Information Systems Applications (incl. Internet)
