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Chia seeds : Tiny superfood, big impact
Chia (Salvia hispanica) is an annual herbaceous plant, the seeds of which were consumed already thousands of years ago. Current research results indicate a high nutritive value for chia seeds and confirm their extensive health-promoting properties. Research indicates that components of chia seeds are ascribed a beneficial effect on the improvement of the blood lipid profile, through their hypotensive, hypoglycemic, antimicrobial and immunostimulatory effects. This article provides a review of the most important information concerning the potential application of chia seeds in food production. The chemical composition of chia seeds is presented and the effect of their consumption on human health is discussed.
Chemotherapy and pharmacology for leukemia in pregnancy : Guidelines and strategies for best practices
The book addresses a broad range of subjects, including: pregnancy and its characteristics; staging, pathology, morbidity and what to expect in each type of leukemia; chemotherapy for leukemia in pregnant women with complete trials; dose adjustment of chemotherapy for leukemia in pregnancy based on serum dosages; and pharmacokinetics and pharmacodynamics for this unique group of patients. In turn, subsequent chapters focus on protecting the fetus and neonatal management regarding chemotherapy for leukemia in pregnancy, including the treatment and risks for the fetus (for each type of leukemia), intrathecal therapy and its effects on the fetus; supportive drugs, antibiotics and antifungals for pregnant patients during chemotherapy, including intervention and dose adjustments; palliative care for women with leukemia in pregnancy; breastfeeding during treatment for leukemia; pharmacological aspects of supplements, vitamins and nutrition in pregnancy during leukemia treatment; and more.
Chemokines and Viral Infection
This edition of Current Topics in Microbiology and Immunology examines the role of chemokines and chemokine receptors in host defense and disease development following viral infection. Chemokines represent a family of over 40 small proteins that, for the most part, are secreted into the environment and function by binding to G protein-coupled receptors (GPCRs) that are expressed on numerous different cell types. When initially identified close to 30 years ago, these molecules were associated with various human inflammatory diseases and it was recognized that expression may be integral in leukocyte recruitment to inflamed tissue. There are now four sub-families of chemokines identified based on defined structural criteria relating to the positional location of conserved cysteine residues within the amino-terminus of the protein. Chemokines are now recognized as important in numerous biological processes ranging from maintaining the organizational integrity of secondary lymphoid tissue to participating in various aspects of both innate and adaptive immune responses following microbial infection. With this in mind, this book highlights the functional roles of chemokines and their receptors in participating in various aspects of the immune response against well-known viral pathogens.
Chemokine biology : Basic research and clinical application ; Vol.1 : Immunobiology of chemokines
The discovery of interleukin-8 close to 20 years ago initiated a new field of research touching on many aspects of immunology and inflammation. Interleukin-8 is just one member of a large class of structurally related chemoattractant proteins, known as chemokines. Chemokines are involved in the traffic control of leukocytes, which bear the corresponding chemokine receptors on their surfaces. Today, it is clear that chemokines affect all aspects of immunology and even many unrelated fields, such as tissue development and tumor cell metastasis. Their fundamental contributions to chronic inflammatory diseases make them a principal target for the development of novel, anti-inflammatory therapeutics.
Chemistry for the Protection of the Environment 4
This volume is the proceedings of the first CPE conference in the new millennium and the thirteenth in a well-established series of conferences on Chemistry for the Protection of the Environment, first established in 1976. With support of the U.S. EPA, the series of conferences provides an opportunity for interdisciplinary exchange of ideas among international specialists, from diverse fields and backgrounds, on the chemical aspects of environmental protection. Over the years, the CPE conferences have gathered participants from more and more countries, and the scope of interests have been broadened. Held in Hilo, Hawaii, this was the first of these international conferences to take place in the United States. The Organizing Committee attracted to the conference a wide range of talented scientists and engineers who have useful ideas to contribute on how to clean our environment.
Chemistry for pharmacy students : General, organic and natural product chemistry ; 2nd ed.
Opens with an overview of the general aspects of chemistry and their importance to modern life, with emphasis on medicinal applications. The text then moves on to discuss the concepts of atomic structure and bonding and the fundamentals of stereochemistry and their significance to pharmacy in relation to drug action and toxicity. Various aspects of organic functional groups, organic reactions, heterocyclic chemistry, nucleic acids and their pharmaceutical importance are then covered in subsequent chapters, with the final chapter dealing with drug discovery and development, and natural product chemistry. Provides a student-friendly introduction to the main areas of chemistry required by pharmacy degree courses. Written at a level suitable for non-chemistry students in pharmacy, but also relevant to those in life sciences, food science, and the health sciences Includes learning objectives at the beginning of each chapter Focuses on the physical properties and actions of drug molecules
Chemistry and Safety of Acrylamide in Food
Specifically covered are the following aspects: exposure from the environment and the diet; biomarkers of exposure; risk assessment; epidemiology; mechanism of formation in food; biological alkylation of amino acids, peptides, proteins, and DNA by acrylamide and its epoxide metabolite glycidamide; neurotoxicity, reproductive toxicity, and carcinogenicity; protection against adverse effects; and possible approaches to reducing levels in food. Cross-fertilization of ideas among several disciplines in which an interest in acrylamide has developed, including food science, pharmacology, toxicology, and medicine, will provide a better understanding of the chemistry and biology of acrylamide in food, and can lead to the development of food processes to decrease the acrylamide content of the diet.
Chemistry and pharmacology of drug discovery
Illustrates how chemistry, biology, pharmacokinetics, and a host of disciplines come together to produce successful medicines, discussing a total of 20 drugs that are all FDA-approved post 2021. Cover Infectious Disease, Cancer Drugs, CNS Drugs, and Miscellaneous Drugs. Each chapter covers background material on the drug class and/or disease indication and key aspects relevant to the discovery of the drug, including structure-activity relationships, pharmacokinetics, drug metabolism, efficacy, and safety.
Chemical Genomics ; Vol.58 : Small Molecule Probes to Study Cellular Function
Chemical genomics is a highly interdisciplinary and very exciting field of research both in academics and in the life sciences industry.Various aspects of the interface between chemistry and biology are covered in this volume, such as chemogenomics efforts in the pharmaceutical industry, diversity-oriented synthesis, chemogenomic approaches to the study of cell function, screening technologies, and natural products as tools in chemical biology.
Chemical Biology of Neurodegeneration : A Molecular Approach
This book focuses on the main actors involved in neurodegenerative disorders at a molecular level, and places special emphasis on structural aspects and modes of action. Drawing on recent data on enzyme structure, mode of action, and inhibitor design, it describes?from a biochemical point of view?the six most important neurotransmitter systems and their constituent enzymes and receptors. Misfolding and aggregation of proteins within the brain is also covered.
Charismatic Christianity in Finland, Norway, and Sweden : Case Studies in Historical and Contemporary Developments
The history of Charismatic Christianity in the Nordic countries reaches as far back as Pentecostalism itself. The bounds of these categories remain a topic of discussion, but Nordic countries have played a vital role for developing this rapidly spreading form of world-wide Christianity. Until now, research on global Charismatic Christianity has largely overlooked the region. This book addresses and analyzes its historical and contemporary trajectories in Finland, Norway and Sweden. Through a selection of cases written by Nordic scholars from various disciplines, it demonstrates historical and contemporary diversity as well as interconnections between local, national, and global currents. Highlighting change and continuity, the anthology reveals new aspects of Charismatic Christianity.
Characterization of Corrosion Products on Steel Surfaces
It is well known that corrosion products, i.e. rust, on iron and steel surfaces cannot be assigned a typical crystallographic structure with long-range order. In fact, the structure of rust is considered to be very complicated, and some forms of rust are assigned to the amorphous state for this reason. Accurate information about the atomic-scale structure of rust is important to shed light on corrosion mechanisms of metallic materials. And, since life of steel structures is often dominated by environmental degradation or corrosion of the surface, the structure of the rust formed on iron and steel surfaces during prolonged exposure to air is of great interest. This book describes the fundamental aspects of materials characterization for the ferric oxyhydroxides formed on steel surfaces.
Changing Aspects in Stroke Surgery : Aneurysms, Dissections, Moyamoya Angiopathy and EC-IC Bypass
What is arterial dissection? What is Moyamoya angiopathy? What is the state of art of AVM treatment? Readers will find answers to these questions in this book. But they will also be informed about the state of the art treatment in the daily stroke therapy.
Chance Rules : An informal guide to probability, risk and statistics
This second edition of Chance Rules again recounts the story of chance through history and the various ways it impacts on our lives. Here you can read about the earliest gamblers who thought that the fall of the dice was controlled by the gods, as well as the modern geneticist and quantum theory researcher trying to integrate aspects of probability into their chosen speciality. Example included in the first addition such as the infamous Monty Hall problem, tossing coins, coincidences, horse racing, birthdays and babies remain, often with an expanded discussion, in this edition. Additional material in the second edition includes, a probabilistic explanation of why things were better when you were younger, consideration of whether you can use probability to prove the existence of God, how long you may have to wait to win the lottery, some court room dramas, predicting the future, and how evolution scores over creationism. Chance Rules lets you learn about probability without complex mathematics.
Challenges to the second law of thermodynamics : Theory and experiment
The second law of thermodynamics is considered one of the central laws of science, engineering and technology. For over a century it has been assumed to be inviolable by the scientific community. Over the last 10-20 years, however, more than two dozen challenges to it have appeared in the physical literature - more than during any other period in its 150-year history. The number and variety of these represent a cogent threat to its absolute status. This is the first book to document and critique these modern challenges. Written by two leading exponents of this rapidly emerging field, it covers the theoretical and experimental aspects of principal challenges. In addition, unresolved foundational issues concerning entropy and the second law are explored. This book should be of interest to anyone whose work or research is touched by the second law.
Challenges in Language Testing Around the World : Insights for language test users
This book combines insights from language assessment literacy and critical language testing through critical analyses and research about challenges in language assessment around the world. It investigates problematic practices in language testing which are relevant to language test users such as language program directors, testing centers, and language teachers, as well as teachers-in-training in Graduate Diploma and Master of Arts in Applied Linguistics programs. These issues involve aspects of language testing such as test development, test administration, scoring, and interpretation/use of test results.
Cellulose : Molecular and Structural Biology : Selected Articles on the Synthesis, Structure, and Applications of Cellulose
Cellulose: Molecular and Structural Biology is an up-to-date treatise on the most advanced and provocative research into the biosynthesis, structure, and applications of nature’s most abundant macromolecule and renewable resource, cellulose.Molecular, biochemical, and evolutionary aspects of cellulose biosynthesis are reviewed in a variety of living organisms, including cyanobacteria, eubacteria, (Acetobacter, Salmonella, and E. coli), vascular plants (including Arabidopsis, forest trees, and maize), and tunicates.
Cellular Automata and Discrete Complex Systems ; 26th IFIP WG 1.5 International Workshop, AUTOMATA 2020, Stockholm, Sweden, August 10–12, 2020, Proceedings
This volume constitutes the refereed post-conference proceedings of the 26th IFIP WG 1.5 International Workshop on Cellular Automata and Discrete Complex Systems, AUTOMATA 2020, held in Stockholm, Sweden, in August 2020. The workshop was held virtually. The 11 full papers presented in this book were carefully reviewed and selected from a total of 21 submissions. The topics of the conference include dynamical, topological, ergodic and algebraic aspects of CA and DCS, algorithmic and complexity issues, emergent properties, formal languages, symbolic dynamics, tilings, models of parallelism and distributed systems, timing schemes, synchronous versus asynchronous models, phenomenological descriptions, scientific modeling, and practical applications.
Cell Stress Proteins
This comprehensive volume, written by experts in the field, provides a current understanding of the molecular properties of the heat shock proteins and their roles in health and disease. Cell Stress Proteins includes advances in several aspects of stress protein research, with chapters ranging from basic studies of the role of heat shock proteins in protein folding to reviews examining the breakdown of stress protein regulation during disease. It also provides analysis of the biochemical and molecular properties of heat shock proteins which can be utilized in evaluating their role in human physiology and pathology. Cell Stress Proteins is an ideal book for researchers, clinicians, physicians, and graduate students in the fields of biochemistry, cell biology, microbiology, immunology, and genetics.
Cell Separation : Fundamentals, Analytical and Preparative Methods
This special volume on cell separations discusses fundamental and applied aspects of the analytical and preparative cell-separation technologies. The aim is to enlighten the reader with the new developments in cell-separation technologies and at the same time provide sufficient knowledge with other existing and more commonly used techniques. The volume is comprised of contributions from subject experts from both academia and industry, focuses on the research and commercial aspects of cell-separation technology, and provides readers with broader choice. Unlike protein separation, the major challenge in cell separation has been the recovery of the cells in viable form after they are bound to the separation matrix, as cells bind more strongly through multipoint attachment. This is an important focus of the present work and one we believe will provide new insight to researchers in this field
