Chemical Biology of Neurodegeneration : A Molecular Approach
- Author
- Pedro Merino
- Publication Year
- 2019
- Publisher
- Wiley-VCH
- Language
- English
- Document Type
- Book
- Faculty / Subject Heading
- Medical Science
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This book focuses on the main actors involved in neurodegenerative disorders at a molecular level, and places special emphasis on structural aspects and modes of action. Drawing on recent data on enzyme structure, mode of action, and inhibitor design, it describes?from a biochemical point of view?the six most important neurotransmitter systems and their constituent enzymes and receptors. Misfolding and aggregation of proteins within the brain is also covered.
Keywords: Chemistry / Pharmaceutical & Medicinal Chemistry / Nerve Degeneration / Molecular Biology / Neurotransmitters