Page 52
Page 52
Fundamentals of drug delivery
A comprehensive guide to the current research, major challenges, and future prospects of controlled drug delivery systems. Provides comprehensive and up-to-date coverage of the essential principles and processes of modern controlled drug delivery systems. Featuring contributions by respected researchers, clinicians, and pharmaceutical industry professionals, this edited volume reviews the latest research in the field and addresses the many issues central to the development of effective, controlled drug delivery.
Fundamentals of drug and non-drug interactions : physiopathological perspectives and clinical approaches
Covers nutrients, active principles from phytotherapy/herbal products, and drug classes while identifying potential interactions. Didactic approaches to drug and non-drug interactions and cutting-edge reports are included in each chapter that promotes safer drug prescription and use. The physiopathological overview in this book provides background for chemistry, pharmacology, and mechanistic bases of drug and non-drug interaction as well as clinical cases and predictive screenings.
Fundamentals of craniofacial malformations ; Vol.1 : Disease and diagnostics
Opens by considering general topics such as developmental biology and disease classification and then examines in depth the biological basis of the various malformations, including craniosynostoses, cleft-lip and palate with complex orofacial clefts, branchio-oculo-facial syndromes, rare syndromes, soft tissue malformations, and dysgnathia. Psychological aspects, including psychological evaluation methods and therapies and quality of life issues, are then addressed. Finally, all relevant clinical, radiological, and genetic investigations are described and important diagnostic issues are explored.
Fundamentals of Clinical Data Science
This book comprehensively covers the fundamentals of clinical data science, focusing on data collection, modelling and clinical applications. Topics covered in the first section on data collection include: data sources, data at scale (big data), data stewardship (FAIR data) and related privacy concerns. Aspects of predictive modelling using techniques such as classification, regression or clustering, and prediction model validation will be covered in the second section. The third section covers aspects of (mobile) clinical decision support systems, operational excellence and value-based healthcare.
Fundamentals of anatomy and physiology of speech, language, and hearing
Each topic is explored in bullet-point form with augmentative paragraph information, in-depth box features, and detailed illustrations. High-resolution Anatomage virtual dissection table figures derived from real cadavers offer an unparalleled glimpse into the anatomical structures of the human body, featuring true-to-life colors and an impressive level of detail. Topics explored include respiration, phonation, articulation, swallowing, resonance, hearing, balance, neuroanatomy, and neurophysiology.
Fundamentals of analytical toxicology : Clinical and forensic ; 2nd ed.
An integrated introduction to the analysis of drugs, poisons, and other foreign compounds in biological and related specimens. Assuming only basic knowledge of analytical chemistry, this invaluable guide helps trainee analytical toxicologists understand the principles and practical skills involved in detecting, identifying, and measuring a broad range of compounds in various biological samples. Clear, easy-to-read chapters provide detailed information on topics including sample collection and preparation, spectrophotometric and luminescence techniques, liquid and gas-liquid chromatography, and mass spectrometry including hyphenated techniques. Focuses on analytical, statistical, and pharmacokinetic principles / Describes basic methodology, including colour tests and immunoassay and enzyme-based assays / Outlines laboratory operations, such as method validation, quality assessment, staff training, and laboratory accreditation / Follows IUPAC nomenclature for chemical names and recommended International Non-proprietary Name (rINN) for drugs and pesticides / Includes discussion of 'designer drugs' (novel pharmaceutical substances NPS)
Fundamentals of nanoscale film analysis
The book describes the fundamentals of materials characterization from the standpoint of the incident photons or particles which interrogate nanoscale structures. These induced reactions lead to the emission of a variety of detected of particles and photons. It is the energy and intensity of the detected beams that is the basis of the characterization of the materials. The array of experimental techniques used in nanoscale materials analysis covers a wide range of incident particle and detected beam interactions.
Fundamental approaches to software engineering ; Vol. 3922 ; 9th International Conference, FASE 2006, Held as Part of the Joint European Conferences on Theory and Practice of Software, ETAPS 2006, Vienna, Austria, March 27-28, 2006, Proceedings
ETAPS 2006 was the ninth instance of the European Joint Conferences on Theory and Practice of Software. ETAPS is an annual federated conference that was established in 1998 by combining a number of existing and new conferences. The events that comprise ETAPS address various aspects of the system devel- ment process, including speci?cation, design, implementation, analysis and impro- ment. The languages, methodologies and tools which support these activities are all well within its scope. Di?erent blends of theory and practice are represented, with an inclination towards theory with a practical motivation on the one hand and soundly based practice on the other. Many of the issues involved in software design apply to systems in general, including hardware systems, and the emphasis on software is not intended to be exclusive.
Fundamental approaches to software engineering ; Vol. 3442 ; 8th International Conference, FASE 2005, Held as Part of the Joint European conferences on theory and practice of software, ETAPS 2005, Edinburgh, UK, April 4-8, 2005, Proceedings
ETAPS 2005 was the eighth instance of the European Joint Conferences on Theory and Practice of Software. ETAPS is an annual federated conference that was established in 1998 by combining a number of existing and new conf- ences. This year it comprised ?ve conferences (CC, ESOP, FASE, FOSSACS, TACAS), 17 satellite workshops (AVIS, BYTECODE, CEES, CLASE, CMSB, COCV, FAC, FESCA, FINCO, GCW-DSE, GLPL, LDTA, QAPL, SC, SLAP, TGC, UITP), seven invited lectures (not including those that were speci?c to the satellite events), and several tutorials. We received over 550 submissions to the ?ve conferences this year, giving acceptance rates below 30% for each one. The events that comprise ETAPS address various aspects of the system - velopment process, including speci?cation, design, implementation, analysis and improvement. The languages, methodologies and tools which support these - tivities are all well within its scope. Di?erent blends of theory and practice are represented, with an inclination towards theory with a practical motivation on the one hand and soundly based practice on the other. Many of the issues involved in software design apply to systems in general, including hardware s- tems,andtheemphasisonsoftwareisnotintendedtobeexclusive.
Fundamental approaches to software engineering ; 11th International Conference, FASE 2008, Held as Part of the Joint European conferences on theory and practice of software, ETAPS 2008, Budapest, Hungary, March 29-April 6, 2008. Proceedings
The fve main conferences received 571 submissions, 147 of which were accepted, giving an overall acceptance rate of less than 26%, with each conference below 27%.Congratulationsthereforetoallthe authorswhomadeittothe alprogramme! I hope that most of the other authors will still have found a way of participating in this exciting event, and that you will all continue submitting to ETAPS and contributing to make of it the best conference in the area،The events that comprise ETAPS address various aspects of the system velopment process,including specifcation, design, implementation, analysis and improvement.
Functions of a-Bounded Type in the Half-Plane
This is a unique book related to the theory of functions of a-bounded type in the half-plane of the complex plane, which is constructed by application of the Liouville integro-differential operator. In addition, the book contains improvements of several results such as the Phragmen-Lindelof Principle and Nevanlinna Factorization in the Half-Plane, and offers a new, equivalent definition of the classical Hardy spaces in the half-plane. The last chapter of the book presents an application of the constructed theory as well as M.M.Djrbashian’s theory of Nevanlinna type classes in the disc in the spectral theory of linear operators. This is a solution of a problem repeatedly stated by M.G.Krein and being of special interest for a long time.
Functionalized Nanoscale Materials, Devices and Systems
The primary objective of the NATO Advanced Study Institute (ASI) titled “Functionalized Nanoscale Materials, Devices, and Systems for Chem. -Bio Sensors, Photonics, and Energy Generation and Storage” was to present a contemporary and comprehensive overview of the field of nanostructured materials and devices and its applications in chem. -bio sensors, nanophotonics, and energy generation and storage devices. The study has become one of the most promising disciplines in science and technology, as it aims at the fundamental understanding of new physical, che- cal, and biological properties of systems and the technological advances arising from their exploration. Such systems are intermediate in size, between the isolated atoms and molecules and bulk material, where the unique transitional characteristics between the two can be understood, controlled, and manipulated.
Functional MRI : Basic principles and clinical applications
This practical and timely volume presents an overview of the principles of fMRI and explains key concepts, including scanning methodologies, experimental research design, and data analysis. Informative discussions cover the technical and clinical challenges associated with fMRI. A neuroanatomical atlas adds to the sensible approach and serves as a useful reference by clearly illustrating normal functioning for important areas of the brain.
Functional Molecular Nanostructures
in This book some recent advances in the structural design of nanoscale assemblies are shown, along with examples from the following areas: supramolecular catalysis, photoactive assemblies, molecular recognition and switches, and electroactive assemblies.The last decade has witnessed an unprecedented pursuit of discrete, nanoscale supramolecular aggregates, built by modern methods of self-assembly strategies. Several efficient new synthetic methods have been developed for engineering spectacular multicomponentsupramolecular aggregates.
Functional Hydrogels in Drug Delivery : Key Features and Future Perspectives
Deals with the synthesis and characterization of hydrogels specifically used as drug delivery systems. Each chapter includes the most recent updates about the different starting materials employed--whether natural and synthetic--and the improvement, such as modifications of synthetic approach and polymerization technique, of their physicochemical and biological properties to synthetize high performing carriers for specific uses, i.e. stimuli-responsive materials, molecularly imprinted polymers, mucoadhesive materials, carrier for the delivery of high molecular weight drugs, and gene-delivery.
Functional Hemodynamic Monitoring
Hemodynamic monitoring is one of the major diagnostic tools available in the acute care setting to diagnose cardiovascular insufficiency and monitor changes over time in response to interventions. However, the rationale and efficacy of hemodynamic monitoring to affect outcome has come into question. We now have increasing evidence that outcome from critical illness can be improved by focused resuscitation based on existing hemodynamic monitoring, whereas non-specific aggressive resuscitation impairs survival. Thus, this book frames hemodynamic monitoring into a functional perspective wherein hemodynamic variables and physiology interact to derive performance and physiological reserve estimates that themselves drive treatment. This philosophy, as well as the limitations and applications of common and evolving hemodynamic measures and their focused use in the care of critically ill patients are discussed, relevant to one underlying truth: No monitoring device, no matter how simple or sophisticated, will improve patient-centered outcomes useless coupled to a treatment which, itself, improves outcome.
Functional Biomaterials : Drug Delivery and Biomedical Applications
Explores in depth a wide range of functional biomaterials-based systems for drug, gene delivery, and biomedical aspects. The chapters cover newer technologies such as polymeric micelle, pH-responsive biomaterials, stimuli-responsive hydrogels, silk fibroin, inorganic biomaterials, synthetic biomaterials, 3D printed biomaterials, metallic biomaterials, ceramic and hybrid biomaterials. It also describes the theranostic approaches for cancer therapy, the biomaterials-based nanofibers scaffolds in tissue engineering, as well as the strategies applications of metallic biomaterials for the medical and dental prosthetic field.
Functional approach to nonlinear models of water flow in soils
The mathematical modelling required by these processes revealed from the beg- ning interesting and dificult mathematical problems, so that the attention was redirected to the theoretical mathematical aspects involved. Then, the qualitative results found were used for the explanation of certain behaviours of the physical processes which had made the object of the initial study and for giving answers to the real problems that arise in the soil science practice. In this way the work evidences a perfect topic for an applied mathematical research.
Functional and operatorial statistics
An increasing number of statistical problems and methods involve infinite-dimensional aspects. This is due to the progress of technologies which allow us to store more and more information while modern instruments are able to collect data much more effectively due to their increasingly sophisticated design. This evolution directly concerns statisticians, who have to propose new methodologies while taking into account such high-dimensional data (e.g. continuous processes, functional data, etc.). The numerous applications (micro-arrays, paleo-ecological data, radar waveforms, spectrometric curves, speech recognition, continuous time series, 3-D images, etc.) in various fields (biology, econometrics, environmetrics, the food industry, medical sciences, paper industry, etc.) make researching this statistical topic very worthwhile. This book gathers important contributions on the functional and operatorial statistics fields
Fuel Oxygenates
purpose of this series on Environmental Chemistrytherefore, is to present a reasonably uniform view of various aspects of the chemistry of the environment and chemical reactions occurring in the environment. The industrial activities of man have given a new dimension to Envir- mental Chemistry. We have now synthesized and described over ?ve million chemical compounds and chemical industry produces about hundred and ?fty million tons of synthetic chemicals annually. We ship billions of tons of oil per year and through mining operations and other geophysical modi?cations, large quantities of inorganic and organic materials are released from their natural deposits.
