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Hybrid Evolutionary Algorithms

Hybridization of evolutionary algorithms is getting popular due to their capabilities in handling several real world problems involving complexity, noisy environment, imprecision, uncertainty and vagueness. This edited volume is targeted to present the latest state-of-the-art methodologies in ’Hybrid Evolutionary Algorithms’. This book deals with the theoretical and methodological aspects, as well as various applications to many real world problems from science, technology, business or commerce. This volume comprises of 14 chapters including an introductory chapter giving the fundamental definitions and some important research challenges. Chapters were selected on the basis of fundamental ideas/concepts rather than the thoroughness of techniques deployed.

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Homing Endonucleases and Inteins

This book provides detailed summary of the genetics, structure, function, mechanisms of action, evolution and engineering of homing endonucleases and inteins. These two unique protein superfamilies have generated considerable excitement for their fundamental, structural, and functional properties, their evolution as parasitic elements, and their widespread applications as gene targeting agents and as instruments for the generation of modified proteins and novel protein combinations.

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Highway

Our idea was generated as a result of the technical and technological shift in almost all industries and its endorsements in reducing costs, increasing efficiency, and serving a wider range of targeted beneficiaries. Three words this business was built on: TRUST, VALUE, and ETHICS. These words are far more endorsed than what the project might explain in terms of business methods, implementations, and processes, but the real aim whether internally or externally is to share the responsibility of improving our industries with creative, competitive ,and relabel business models that could put companies on the wheel of quality improvement and potentially wider the range of the jobs market.

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High-Resolution If-To-Baseband ΣΔ Adc For Car Radios

High-Resolution IF-to-Baseband SigmaDelta ADC for Car Radios addresses the theory, system level design and circuit implementation of a high-resolution continuous-time IF-to-baseband quadrature SigmaDelta ADC. The target application of this ADC is in AM/FM/IBOC car radios. The ADC achieves a dynamic range of 118dB, which eliminates the need for an IF VGA or AM channel filter in car radios.

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Herbal pharmacopeia : Nanotechnology and advancing drug

Explores the intersection between traditional herbal medicine and cutting-edge nanotechnology. The chapters introduce modern techniques used in herbal extraction and analysis. The principles of drug discovery from plants are discussed, with a focus on the identification and development of bioactive compounds that have therapeutic potential. It discusses the pharmacological properties, biotechnological approaches in drug development, and challenges in the formulation and standardization of herbal medicines. Emerging trends and applications of nanotechnology in herbal pharmacotherapy, such as nanoparticle synthesis, enhanced bioavailability using nanocarriers, safety assessments, novel and targeted delivery systems, and regulatory considerations, are thoroughly discussed. Additionally, it includes a comparative analysis of traditional and nano-formulated approaches and their implementation in clinical settings. Towards the end, the book reviews the regulatory considerations for herbal products and future perspectives in herbal pharmacopeia. This book is intended for researchers, clinicians, and professionals in herbal medicine, pharmacology, and nanotechnology.

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Heat Shock Proteins in Cancer

Heat shock proteins are emerging as important molecules in the development of cancer and as key targets in cancer therapy. These proteins enhance the growth of cancer cells and protect tumors from treatments such as drugs or surgery.

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Headache and Chronic Pain Syndromes

Headache and Chronic Pain Syndromes provides a case-based approach to state-of-the-art evaluation and treatment of patients with common chronically painful conditions. Offering strategies for rapidly evaluating and treating pain complaints by body region, this innovative title also provides patient educational handouts that explain the diagnosis and treatment in easy-to-understand language for each condition. Tools for implementing both medication and non-medication therapies, such as exercises and relaxation techniques, are also included. Each chapter opens with typical presentations of three to five common patient scenarios, including pediatric, adult, and geriatric patients. A targeted approach for patient assessment is provided and applied to each scenario, showing how to rapidly identify important clues to distinguish among common diagnoses, including both benign and malignant causes of pain. Standard treatment regimens are then provided for each patient, along with patient-friendly educational flyers for each common pain condition. Figures and drawings help provide ready identification of these common chronic pain syndromes.

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Handhelds in medicine : A practical guide for clinicians

Handheld computers are emerging as the stethoscopes of the twenty-first century, and no clinician should be without! These small, easy-to-use devices are now powerful enough to help clinicians manage information and make medical decisions at the point of care. Here, Drs. Stayer, Reynolds and Ebell, practicing physicians and nationally recognized handheld computing experts, show you how to make the most of a handheld computer in your medical practice. This comprehensive how-to guide targets all levels of handheld computer users from novices to experts. It is designed with easy-to-understand hands-on exercises that walk readers through each new skill presented. For beginners, the first section is devoted to "getting to know your handheld," choosing or upgrading a handheld computer, and the basics of handheld operation. There's also a comprehensive chapter on downloading and installing software. Futher sections delve into different types of medical and nonmedical software, Internet and evidence-based resources for medical handheld computing, and, finally, advanced topics such as designing custom software and going wireless. Even the most advanced user will find a lot to learn in this book.

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Handbook of Radiopharmaceuticals : Methodology and Applications ; 2nd ed.

A comprehensive review of the field, presenting up-to-date coverage of central topics such as radionuclide production, synthetic methodology, radiopharmaceutical development and regulations, and a wide range of practical applications. A valuable reference work for those new to the Radiopharmaceutical Sciences and experienced professionals alike, this volume explores the latest concepts and issues involving both targeted diagnostic and therapeutic radiopharmaceuticals. Contributions from a team of experts from across sub-disciplines provide readers with an immersive examination of radiochemistry, nuclear medicine, molecular imaging, and more. Features extensive new and revised content throughout Covers key areas of application for diagnosis and therapy in oncology, neurology, and cardiology Emphasizes the multidisciplinary nature of Radiopharmaceutical Sciences Discusses how drug companies are using modern radiopharmaceutical imaging techniques to support drug discovery Examines current and emerging applications of Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT)

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Handbook of nanoencapsulation : Preparation, characterization, delivery, and safety of nutraceutical nanocomposites

Nutraceutical encapsulation envelopes protection of products from oxidative damage, controlled delivery of nanoencapsulated nutraceuticals and improved nutraceutical bioavailability as well as biological action. It is a promising technique to ensure the stabilization of such labile compounds and to protect the core ingredients from premature reactions and interactions In a comprehensive manner, the Handbook of Nanoencapsulation: Preparation, Characterization, Delivery and Safety of Nutraceutical Nanocomposites presents various nanosystems/nanocarriers, physical and chemical techniques used in encapsulation of various nutraceuticals, and the targeted delivery of various significant nutraceuticals.

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Handbook of molecular force spectroscopy

Modern materials science and biophysics are increasingly focused on studying and controlling intermolecular interactions on the single-molecule level. Molecular force spectroscopy was developed in the past decade as the result of several unprecedented advances in the capabilities of modern scientific instrumentation, and defines a number of techniques that use mechanical force measurements to study interactions between single molecules and molecular assemblies in chemical and biological systems. Examples of these techniques, which typically target a specific range of experimental systems and geometries, include atomic force microscopy, optical tweezers, surface forces apparatus, and magnetic tweezers.

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Handbook of In Vivo Chemistry in Mice : From Lab to Living System

The Handbook of In Vivo Chemistry in Mice: From Lab to Living System introduces readers to general information about live animal experiments and detection methods commonly used for these animal models. It focuses on chemistry-based techniques to develop selective in vivo targeting methodologies, as well as strategies for in vivo chemistry and drug release.

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Half-metallic Alloys : Fundamentals and Applications

Half-metals are particular ferromagnetic materials which can be considered as hybrids between metals and semiconductors. A particular feature of these materials is that electrons at the Fermi level show complete spin polarization making them prime targets for research into suitable divices for spin electronics. This book is both an introduction and state-of-art survey of the latest advances in the understanding and applications of Heusler alloys and related compounds.

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Guide your education website

This platform is targeting more than one segment in the Damascene community and its suburbs. But first, I need to acknowledge mission of my work as a helping tool segmented in the educational sector to save time and effort of the users in finding the thing they are looking for by offering the right program that meets their own needs in a professional and efficient way. Thus, this will lead to the main purpose of my vision; me as an MIS graduated I dream of being the first facilitator in offering the right platform to the right people in the best way. That is why my slogan is “availability of information is for everyone”.

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Guide to Biomolecular Simulations

Molecular dynamics simulations have become instrumental in replacing our view of proteins as relatively rigid structures with the realization that they were dynamic systems, whose internal motions play a functional role. Over the years, such simulations have become a central part of biophysics. Applications of molecular dynamics in biophysics range over many areas. They are used in the structure determination of macromolecules with x-ray and NMR data, the modelling of unknown structures from their sequence, the study of enzyme mechanisms, the estimation of ligand-binding free energies, the evaluation of the role of conformational change in protein function, and drug design for targets of known structures.

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Guide to Assembly Language Programming in Linux

This unique guide provides comprehensive coverage of the key elements of Assembly language programming with in-depth coverage of the Linux operating system, which is the fastest-growing operating system with an estimated 18 million Linux users worldwide. The book specifically targets professionals who would like to learn Assembly and intend or expect to move to the Linux operating system. This highly useful guidebook comes complete with all the necessary software (Linux, NASM, debugger), making it an extremely valuable resource tool for all those who want to learn Assembly programming and Linux. Readers need only have a basic knowledge of any structured, high-level language such as C to obtain the full benefits of this guidebook.

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Group interventions in schools : Promoting mental health for at-risk children and youth

Children who are labeled at-risk often suffer from severe deficiencies in cognitive, affective, and behavioral skills that, if unaddressed, may lead to limited prospects for future success and well-being. Tapping into the therapeutic potential of groups, this volume presents the theory and practice of cognitive-oriented group-centered counseling – combining intrinsic motivation, efficacy retraining, and targeted play therapy and social role-playing – that can be implemented to help children build core social skills and emotional regulation to complement their classroom instruction.

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GPCRs as Therapeutic Targets ; 2-Vol. Set

Delivers an authoritative and in-depth compendium of a vibrant and active area of academic and industrial drug discovery. The book serves as an important reference for new and experienced researchers studying G protein-coupled receptors and discusses the molecular pharmacology of this important target class. It also includes up-to-date material on GPCR structures and structure-based drug design.

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GPCRs : From Deorphanization to Lead Structure Identification

The book highlights the following topics: Structure of GPCRs, Design of GPCR Ligands, GPCR Signalling, Deorphanization and Assay Development. All chapters are written by leading experts in the field, discussing the most recent state of the art. They give insight into the approaches taken by industry and academia to address GPCRs and depict how mature this target class-oriented research has become in the last decade. The book reflects the actual trends in the fast-emerging field of GPCR research in academia and industry.

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Glutamate Receptors in Peripheral Tissue : Excitatory Transmission Outside the CNS

The book is divided into three sections— Part I is on general concepts and concentrates on the distribution and cell-specific localiza­ tion of glutamate receptors, their transporters, and the pharmacology in peripheral tissues and organs. Part II emphasizes the presence and implications of these receptors in specific target tissues, organs, and systems, including liver, lungs, endocrine tissues, bone, immune system, etc. Part III focuses on glutamate receptors in plants to illustrate their presence beyond the animal kingdom.

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