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Micro-Place Homicide Patterns in Chicago : 1965 - 2017

This brief examines 36,263 homicides in Chicago over a 53-year study period, 1965 through 2017, at micro place grid cells of 150 by 150 meters. This study shows not only long-term historical patterns of homicides in Chicago, but also places that historical context of homicide in reference to the dramatic increases in homicides in 2016-2017. It uses several different inequality metrics, as well as kernel density maps to demonstrate that homicides were more clustered in the 1960’s compared to later periods. Using zero inflated group-based trajectory models, it demonstrates the long-term temporal stability of homicides at micro places. This brief will be of interest to researchers in policing, homicide, and research methods in criminology.

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Microfluidic Technologies for Miniaturized Analysis Systems

Microfluidic Technologies for Miniaturized Analysis Systems provides a comprehensive overview of the fluidic aspects of Lab-on-a-Chip technology. This book describes the most important and state-of-the-art microfluidic technologies and the underlying principles utilized in the implementation of fluidic protocols of miniaturized analysis systems. This book discusses many of the effects, outcomes, and techniques which are unique to microfluidic systems. The specific components of this technology toolbox are elucidated through research and examples presented by some of the most renowned experts in the field.

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Microbial Linear Plasmids

Microbial Linear Plasmids constitutes the first attempt to comprehensively assemble current knowledge of different types of such elements, highlight recent developments in the field, and challenge the distinction between viruses and linear plasmids.

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Microarrays in Inflammation

The book is of interest to academic and industrial researchers but also clinicians who are working on inflammation related topics and would like to extend their knowledge about microarrays and the application thereof. After reading the book a researcher or clinician should be in the position to plan, perform and analyse or to critically review microarray experiments related to inflammation research.

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Micro-, Meso- and Macro-Connectomics of the Brain

Highlights cutting-edge methods that can accelerate progress in elucidating static ‘hard-wired’ circuits of the brain as well as dynamic interactions that are vital for brain function. The power of connectomic approaches in characterizing abnormal circuits in the many brain disorders that afflict humankind is considered. Experts in computational neuroscience and network theory provide perspectives needed for synthesizing across different scales in space and time. Altogether, this book provides an integrated view of the challenges and opportunities in deciphering brain circuits in health and disease.

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Methods of Celestial Mechanics: Vol. I: Physical, Mathematical, and Numerical Principles

G. Beutler's Methods of Celestial Mechanics is a coherent textbook for students in physics, mathematics and engineering as well as an excellent reference for practitioners. This Volume I gives a thorough treatment of celestial mechanics and presents all the necessary mathematical details that a professional would need. After a brief review of the history of celestial mechanics, the equations of motion (Newtonian and relativistic versions) are developed for planetary systems (N-body-problem), for artificial Earth satellites, and for extended bodies (which includes the problem of Earth and lunar rotation). Perturbation theory is outlined in an elementary way from generally known mathematical principles without making use of the advanced tools of analytical mechanics. The variational equations associated with orbital motion - of fundamental importance for parameter estimation (e.g., orbit determination), numerical error propagation, and stability considerations - are introduced and their properties discussed in considerable detail. Numerical methods, especially for orbit determination and orbit improvement, are discussed in considerable depth. The algorithms may be easily applied to objects of the planetary system and to Earth satellites and space debris.

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Methods of Celestial Mechanics ; Vol. II : Application to Planetary System, Geodynamics and Satellite Geodesy

G. Beutler's Methods of Celestial Mechanics is a coherent textbook for students as well as an excellent reference for practitioners. Volume II is devoted to the applications and to the presentation of the program system CelestialMechanics. Three major areas of applications are covered: (1) Orbital and rotational motion of extended celestial bodies. The properties of the Earth-Moon system are developed from the simplest case (rigid bodies) to more general cases, including the rotation of an elastic Earth, the rotation of an Earth partly covered by oceans and surrounded by an atmosphere, and the rotation of an Earth composed of a liquid core and a rigid shell (Poincaré model). (2) Artificial Earth Satellites. The oblateness perturbation acting on a satellite and the exploitation of its properties in practice is discussed using simulation methods (CelestialMechanics) and (simplified) first order perturbation methods. The perturbations due to the higher-order terms of the Earth's gravitational potential and resonant perturbations are considered thereafter. Special attention is paid to satellites of the Global Navigation Satellite Systems and to geostationary satellites. The characteristics of and models for the two most important non-gravitational forces, atmospheric drag and radiation pressure, are presented as well as the most relevant forces acting on high- and low-orbiting satellites. (3) Evolution of the Planetary System. The outer planetary system consisting of the planets Jupiter to Pluto is studied over long time intervals using simulation methods and spectral analysis (CelestialMechanics). The properties of the inner systems, in particular of the Earth's orbit, are made visible by integrating the entire system over long time intervals relevant for climate change. The distribution of minor planets and their orbital properties, regular orbits, and chaotic orbits are easily generated and analyzed using CelestialMechanics. The volume concludes with the discussion of important mathematical tools of the program system and of the principles of spectral analysis.

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Methods in Nonlinear Analysis

Nonlinear analysis has developed rapidly in the last three decades. Theories, techniques and results in many different branches of mathematics have been combined in solving nonlinear problems. This book collects and reorganizes up-to-date materials scattered throughout the literature from the methodology point of view, and presents them in a systematic way. It contains the basic theories and methods with many interesting problems in partial and ordinary differential equations, differential geometry and mathematical physics as applications.There are five chapters that cover linearization, fixed-point theorems based on compactness and convexity, topological degree theory, minimization and topological variational methods. Each chapter combines abstract, classical and applied analysis. Particular topics included are bifurcation, perturbation, gluing technique, transversality, Nash–Moser technique, Ky Fan's inequality and Nash equilibrium in game theory, set­valued mappings and differential equations with discontinuous nonlinear terms, multiple solutions in partial differential equations, direct method, quasi­convexity and relaxation, Young measure, compensation compactness method and Hardy space, concentration compactness and best constants, Ekeland variational principle, infinite-dimensional Morse theory, minimax method, index theory with group action, and Conley index theory.

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Metastasis of Prostate Cancer

Without metastasis, prostate cancer would be both tolerable and treatable. The high incidence of indolent and organ confined disease is testament to this sweeping generalisation. Equally, if molecular markers of metastatic spread can be identified, then the choice of treatment for many patients would be easier and more radical, even curative. However, should prevention and treatment of the primary tumors prove difficult or impossible.

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Metaheuristics for Hard Optimization : Methods and Case Studies

Metaheuristics for Hard Optimization comprises of three parts. The first part is devoted to the detailed presentation of the four most widely known metaheuristics: the simulated annealing method, tabu search, the evolutionary algorithms, and ant colony algorithms. Each one of these metaheuristics is actually a family of methods, of which the essential elements are discussed. In the second part, the book presents some other less widespread metaheuristics, then, extensions of metaheuristics and some ways of research are described . The problem of the choice of a metaheuristic is posed and solution methods are discussed. The last part concentrates on three case studies from telecommunications, air traffic control, and vehicle routing.

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Metaheuristic Optimization via Memory and Evolution : Tabu Search and Scatter Search

Tabu Search (TS) and, more recently, Scatter Search (SS) have proved highly effective in solving a wide range of optimization problems, and have had a variety of applications in industry, science, and government. The goal of METAHEURISTIC OPTIMIZATION VIA MEMORY AND EVOLUTION: Tabu Search and Scatter Search is to report original research on algorithms and applications of tabu search, scatter search or both, as well as variations and extensions having "adaptive memory programming" as a primary focus. Individual chapters identify useful new implementations or new ways to integrate and apply the principles of TS and SS, or that prove new theoretical results, or describe the successful application of these methods to real world problems.The chapters of this book provide a series of landmarks along the way as we investigate and seek to better understand the elements of tabu search and scatter search that account for their successes in an astonishingly varied range of applications.

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Memories in Wireless Systems

This book is a guide which treats many components used in mobile communications, and in particular focuses on non-volatile memories. It emerges following the conducting line of the non-volatile memory in the wireless system: On the one hand it develops the foundations of the interdisciplinary issues needed for design analysis and testing of the system. On the other hand it deals with many of the problems appearing when the systems are realized in industrial production. These cover the difficulties from the mobile system to the different types of non-volatile memories.

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Medication problems and consequences due to the misuse of chronic drugs

All medicines can cause harm as well as benefit. Without systematic scientific evidence of benefit, no harmful effect, however rare, is worth the risk. This message is hardly revolutionary; it is one of the key principles of drug regulation Across all care environments, pharmacists play an essential role in the care of people who use and misuse of drug Medication history errors potentially clinically important, Improved physician training, accessible community pharmacy databases and closer teamwork between patients, physicians and pharmacists could reduce the frequency of these errors.

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Medical Retina

Although the treatment of retinal diseases remains one of the most challenging fields in ophthalmology, the standard of knowledge has improved substantially over the past few years. The insight into basic mechanisms of disease has been expanded and novel diagnostic and therapeutic strategies have been developed, bridging the gap between laboratory and clinical science.

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Medical Malpractice : A Physician's Sourcebook

In Medical Malpractice: A Physician's Sourcebook, a panel of physicians, attorneys, academics, researchers, and insurance industry experts consider these and other questions about the origin, nature, and ramifications of the medical malpractice litigation crisis, as well as possible solutions and alternatives to the current system. The authors focus on the clinical face of litigation from the perspective of the practicing physician in a variety of specialties, ranging from family and emergency medicine to anesthesiology, obstetrics, gynecology, and plastic surgery. Special consideration is given to breast cancer and Pap smear litigation, risk management for the family physician, and the importance of effective patient communication.. Authoritative and wide-ranging, Medical Malpractice: A Physician's Sourcebook gets to the heart of issues facing physicians and surgeons today. It focuses on the practical aspects of medical malpractice lawsuits, and prepares physicians and surgeons to participate in the public policy debate by addressing current topics that will help them understand the crisis, the threat to healthcare access, and the possibilities for legal reform.

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Mechanics of Biological Tissue

The mechanics of biological tissues is a multidisciplinary and rapidly expanding area of research. This book highlights some important research directions that combine mechanical sciences with exciting new developments in biology. This collection of papers should be of interest to theoretical, computational and experimental researchers and doctoral students in the area of biomechanics and in related areas of engineering, biology and medicine.

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Mechanical Ventilation

This book represents a state-of-the-art review by the leading experts in this field and covers a number of important topics including epidemiology, underlying physiological concepts, and approaches to monitoring. The pros and cons of various modes of ventilation are reviewed, as are novel forms of ventilation that may play a role in the future management of patients with respiratory failure. The importance of patient-ventilator synchrony and ventilator-induced lung injury are reviewed, with a focus on recent clinical trials and the challenges of implementing the results into clinical practice.

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Mechanical Behaviour of Engineering Materials : Metals, Ceramics, Polymers, and Composites

How do engineering materials deform when bearing mechanical loads? To answer this crucial question, the book bridges the gap between continuum mechanics and materials science. The different kinds of material deformation (elasticity, plasticity, fracture, creep, fatigue) are explained in detail. The book also discusses the physical processes occurring during the deformation of all classes of engineering materials (metals, ceramics, polymers, and composites) and shows how these materials can be strengthened to meet the design requirements. It provides the knowledge needed in selecting the appropriate engineering material for a certain design problem. The reader will thus learn how to critically employ design rules and thus to avoid failure of mechanical components.

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Mathematics of Financial Markets

This book presents the mathematics that underpins pricing models for derivative securities, such as options, futures and swaps, in modern financial markets. The idealized continuous-time models built upon the famous Black-Scholes theory require sophisticated mathematical tools drawn from modern stochastic calculus. However, many of the underlying ideas can be explained more simply within a discrete-time framework. This is developed extensively in this substantially revised second edition to motivate the technically more demanding continuous-time theory, which includes a detailed analysis of the Black-Scholes model and its generalizations, American put options, term structure models and consumption-investment problems. The mathematics of martingales and stochastic calculus is developed where it is needed.

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Mathematics Education and Language Diversity : The 21st ICMI Study

This book examines multiple facets of language diversity and mathematics education. It features renowned authors from around the world and explores the learning and teaching of mathematics in contexts that include multilingual classrooms, indigenous education, teacher education, blind and deaf learners, new media and tertiary education. Each chapter draws on research from two or more countries to illustrate important research findings, theoretical developments and practical strategies.

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