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Reverse engineering of regulatory networks
Details the development of updated dry lab and wet lab based methods for the reconstruction of Gene regulatory networks (GRN). And guide readers through culprit genes, in-silico drug discovery techniques, genome-wide ChIP-X data, high-Throughput Transcriptomic Data Exome Sequencing, Next-Generation Sequencing, Fuorescence Spectroscopy, data analysis in Bioinformatics, Computational Biology, and S-system based modeling of GRN.
Research in computational molecular biology ; Vol. 3909 ; 10th Annual International Conference, RECOMB 2006, Venice, Italy, April 2-5, 2006, Proceeding
Contains the papers presented at the 10th Annual International Conference on Research in Computational Molecular Biology (RECOMB 2006),which was held in Venice, Italy, on April 2–5, 2006.
Research in computational molecular biology ; 9th Annual international conference, RECOMB 2005, Cambridge, MA, USA, May 14-18, 2005, Proceedings
From RECOMB 2005, the Steering Committee decided to publish the proceedings as a volume of Lecture Notes in Bioinf- matics (LNBI) for which the founders of RECOMB are also the editors. The prominent volume number LNBI 3500 was assigned to this proceedings. The RECOMB conference series is closely associated with the Journal of Compu- tional Biology which traditionally publishes special issues devoted to presenting full versions of selected conference papers.
Research in computational molecular biology ; 12th Annual International Conference, RECOMB 2008, Singapore, March 30 - April 2, 2008. Proceedings
This book constitutes the refereed proceedings of the 19th Annual International Conference on Research in Computational Molecular Biology, RECOMB 2015, held in Warsaw, Poland, in April 2015. The 36 extended abstracts were carefully reviewed and selected from 170 submissions. They report on original research in all areas of computational molecular biology and bioinformatics.
Research in computational molecular biology ; 11th Annunal International Conference, RECOMB 2007, Oakland, CA, USA, April 21-25, 2007, Proceedings
This book constitutes the refereed proceedings of the 11th Annual International Conference on Research in Computational Molecular Biology, RECOMB 2007, held in Oakland, CA, USA in April 2007.The 37 revised full papers address all current issues in algorithmic, theoretical, and experimental bioinformatics.
Reconfigurable computing : Accelerating computation with field-programmable gate arrays
By mapping algorithms directly into programmable logic, FPGA accelerators offer and deliver 10X-100X performance increases over microprocessors for a large range of application domains. Reconfigurable computing is found in virtually every computing milieu, from satellites to supercomputers. This work survey various aspects of the field.
Reasoning Web ; Vol. 4126 ; 2nd International Summer School 2006, Lisbon, Portugal, September 4-8, 2006, Tutorial Lectures
This book presents thoroughly arranged tutorial papers corresponding to lectures given by leading researchers at the Second International Summer School on Reasoning Web in Lisbon, Portugal, in September 2006.
Reasoning Web : 4th International Summer School 2008, Venice, Italy, September 7-11, 2008, Tutorial Lectures
This book is presented provide competent coverage of methods and major application areas such as social networks, semantic multimedia indexing and retrieval, bioinformatics, and semantic web services. They highlight which techniques are already being successfully applied for purposes such as improving the performance of information retrieval algorithms, enabling the interoperation of heterogeneous agents, modelling users profiles and social relations, and standardizing and improving the accuracy of very large and dynamic scientific databases.
Real World Applications of Computational Intelligence
This book presents a careful selection of the field that very well reflects the breadth of the discipline. It covers a range of highly relevant and practical design principles governing the development of intelligent systems in data mining, robotics, bioinformatics, and intelligent tutoring systems.
Quantifying Quality of Life : Incorporating Daily Life into Medicine
This book presents the rise of technology-enabled methods and tools for objective, quantitative assessment of Quality of Life (QoL), while following the WHOQOL model. It is an in-depth resource describing and examining state-of-the-art, minimally obtrusive, ubiquitous technologies. Highlighting the required factors for adoption and scaling of technology-enabled methods and tools for QoL assessment, it also describes how these technologies can be leveraged for behavior change, disease prevention, health management and long-term QoL enhancement in populations at large.
Proteomics of Human Bodyfluids : Principles, Methods, and Applications
In Proteomics of Human Body Fluids: Principles, Methods, and Applications, top experts provide the premier collection of proteomics applications designed to analyze various human body fluids. Beginning with basic principles and strategies then exploring methodologies, recent findings, and clinical applications, this authoritative volume covers its subject in great detail from many angles.
Proteomics for drug discovery
Explores a wide range of experimental and bioinformatic proteomics methods applicable to the drug discovery process. Focused on drug target discovery, validation, characterization, and quantitation, the book delves into bottom-up data-dependent (DDA) shotgun and data-independent acquisition (DIA) proteomics, cell surface proteomics, proteogenomics, chemoproteomics, methodologies focused on posttranslational modifications, single cell proteomics, 3D cell culture proteomics, organoids, and laser capture microdissection (LCM) assisted tissue proteogenomics. Advanced quantitative techniques, which include label-free, mass tagging, and targeted immuno-MRM proteomics, along with top-down proteomics for validation and characterization of selected protein targets, are also described.
Proteomics for Biological Discovery
Proteomics for Biological Discovery begins by discussing the emergence of proteomics technologies and summarizing the potential insights to be gained from proteome-level research. The tools of proteomics, from conventional to novel techniques, are thoroughly covered, from underlying concepts to limitations and future directions. Later chapters provide an overview of the current developments in post-translational modification studies, structural proteomics, biochemical proteomics, applied proteomics, and bioinformatics relevant to proteomics.
Proteomics and Protein-Protein Interactions : Biology, Chemistry, Bioinformatics, and Drug Design
Techniques have been developed to rapidly create protein-protein interactions maps which in turn can be organized into pathways. Proteins serving as hubs in these networks seem to play crucial biological roles. Some of these proteins may provide new pharmalogical targets for an industry which is rapidly running out of the more classical means of finding new markets. Proteomics and Protein-Protein Interactions: Biology, Chemistry, Bioinformatics, and Drug Design aims at providing a comprehensive yet entertaining view of this rapidly evolving and exciting field. It starts with an overview of the importance of protein-protein interaction in biology (Chapter I). Next, the book dives into Proteomics issues (Chapter II) and describes successful applications of the Proteomics approach. Chapter III focuses on the very specific roles that protein modules play in determining and regulating protein-protein interactions while chapter IV addresses the chemical and energetic underpinnings of such macromolecular interactions. The data generated by a Proteomics approach is abundant and will only be made sense of using bio-informatics: chapter V is dedicated to giving a voice to some of the leaders in the bio-informatics field. Finally, in chapter VI, examples are provided to illustrate the great potential that protein-protein interfaces have as targets for pharmaceutical
Proteome Research : Concepts, Technology and Application
This book provides a clear conceptual description of each facet of proteomics, describes recent advances in technology and thinking in each area, and provides details of how these have been applied to a variety of biological problems. It provides junior and experienced researchers with an invaluable proteomic reference, and gives fascinating glimpses of the future of this dynamic field.
Protein Analysis and Purification : Benchtop Techniques
New technologies and the manner in which scientific research is conducted have been fully incorporated into this thoroughly revised second edition of PROTEIN ANALYSIS AND PURIFICATION. Among the many topics introduced to this new edition are the use of robotics in the lab, the impact of the codification of the human genome, functional proteomics, mass spectrometry and the expanding use of bioinformatics as a tool to improve efficiency and productivity
Proteases and cancer : Methods and protocols
Details bioinformatics analysis, biochemical assays, recombinant protein expression and purification, methods to investigate protease activity in cell-based, organoids and in vivo systems, proteomics, transcriptomics, machine learning and novel approaches to target dysregulated protease activity in cancer. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Progress in pattern recognition, image analysis and applications ; 13th Iberoamerican Congress on Pattern Recognition, CIARP 2008, Havana, Cuba, September 9-12, 2008. Proceedings
This book is organized in topical sections on signal analysis for characterization and filtering, analysis of shape and texture, analysis of speech and language, data mining, clustering of images and documents, statistical pattern recognition, classification and description of objects, classification and edition, geometric image analysis, neural networks, computer vision, image coding, associative memories and neural networks, interpolation and video tracking, images analysis, music and speech analysis, as well as classifier combination and document filtering.
Progress in Artificial Life ; 3rd Australian Conference, ACAL 2007 Gold Coast, Australia, December 4-6, 2007 Proceedings
This book constitutes the refereed proceedings of the Third Australian Conference on Artificial Life, ACAL 2007, held in Gold Coast, Australia, in December 2007. Research in Alife covers the main areas of biological behaviour as a metaphor for computational models, computational models that reproduce/duplicate a biological behaviour, and computational models to solve biological problems.
Progress in Artificial Intelligence ; 13th Portuguese Conference on Artificial Intelligence, EPIA 2007, Workshops: GAIW, AIASTS, ALEA, AMITA, BAOSW, BI, CMBSB, IROBOT, MASTA, STCS, and TEMA, Guimarães, Portugal, December 3-7, 2007, Proceedings
This book constitutes the refereed proceedings of the 13th Portuguese Conference on Artificial Intelligence, EPIA 2007, held in Guimaraes, Portugal, in December 2007 as eleven integrated workshops. In accordance with the eleven constituting workshops, the papers are organized in topical sections on a broad range of subjects.
