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Therapeutic Lipidology ; 2nd ed.
The chapters focus on recent advances in the field including novel biomarkers and the microbiome, genomics of cardiovascular risks, PCSK9 inhibitors, imaging technologies, and epidemiology of atherosclerotic cardiovascular disease. The book describes new guidelines, novel therapeutic agents, and changes in the understanding of specific lipoproteins and subclasses with regard to their relationships to cardiovascular disease risk. The second edition contains more than thirty chapters covering such topics as the history of lipidology, lipoprotein metabolism and vascular biology, disorders of lipid metabolism, lifestyle/dietary and pharmacologic management for dyslipidemia, the management of dyslipidemia in certain subgroups (e.g., women, children, older patients) and lipid testing, as well as an examination of other biomarkers and testing procedures related to atherosclerosis and cardiovascular disease.
Therapeutic drug targets and phytomedicine For triple negative breast cancer
Provides an overview of TNBC etiology, its treatment strategies and prognostic markers to identify the outcome of standard therapies. Signalling pathways namely cell proliferation, angiogenesis, invasion and metastasis, apoptosis, autophagy and others involved in complicating the disease have been described in the chapters to convey an understanding about the disease mechanisms. All the possible drugs either in pre-clinical or clinical stages have also been mentioned with data that depicts their efficiency in targeting altered genes. Introduces the reader to herbal medicine exhibiting high potency to target TNBC, their synthetic analogs used during chemotherapy and their ability to fight against chemoresistance. The concept of phytonanotechnology has also been discussed. Helps create awareness among a broad range of readers about TNBC. It points to prioritizing the upgradation of health care facilities and re-designing future treatment strategies to provide maximum benefit to breast cancer patients.
Theory of Quantum Transport in Metallic and Hybrid Nanostructures
A new science emerges at the intersection of modern physics, computer s- ence,andmaterialscience. Thestruggletofurtherminiaturizeisputtingna- technology to the verge of creating single-electron and/or single-spin devices that operate by moving a single electron (spin) and can serve as transistors, memory cells, and for logic gates. These devices take advantage of quantum physics that dominates nanometer size scales. The devices that utilize met- based hybrid nanostructures may possess signi?cant advantages over those exploiting purely semiconducting materials. First, the chemistry of metals is typically simpler than that of semiconductors. Second, the electric properties of metals are much less sensitive to the structural defects and impurities than those of semiconductors. Next, metallic devices allow better electric and th- mal contacts. Another important plus point is that in metals the electron de Broigle wavelength is smaller by many orders of magnitude as compared to that in semiconductor
Theory of Copper Oxide Superconductors
This is an advanced textbook for graduate students and researchers wishing to learn about high temperature superconductivity in copper oxides, in particular the Kamimura-Suwa (K-S) model. Because a number of models have been proposed since the discovery of high temperature superconductivity by Bednorz and Müller in 1986, the book first explains briefly the historical development that led to the K-S model. It then focuses on the physical background necessary to understand the K-S model and on the basic principles behind various physical phenomena such as electronic structures, electrical, thermal and optical properties, and the mechanism of high temperature superconductivity.
Theory and Practice of Model Transformations ; 1st International Conference, ICMT 2008, Zürich, Switzerland, July 1-2, 2008 Proceedings
This book includes different issues related with: process and engineering of model transformations; model transformations supporting concurrency and time; matching and mapping within model transformation rules; language support for model transformation reuse and modularity; and correctness and analysis of model transformations.
Theories of Perception in Medieval and Early Modern Philosophy
Sense perception is one of the classical themes in philosophy. It is traditionally considered a necessary preamble to many important topics, such as the mind-body relationship, consciousness, knowledge, and scepticism. Perception is also a phenomenon which itself raises philosophical questions, such as what is perceptible, what the content of perception is, whether this content is conceptual and how perception is related to epistemic attitudes. While the philosophy of mind and philosophical psychology are the main areas in which perception is dealt with in contemporary philosophy, it is also discussed in the theory of knowledge, cognitive science, philosophical aesthetics and metaphysics. In recent years, the rich tradition of various philosophical theories of perception has been increasingly studied by scholars of the history of philosophy of mind.
Theories in and of Mathematics Education : Theory Strands in German Speaking Countries
This survey provides an overview of German meta-discourse on theories and mathematics education as a scientific discipline, from the 1970s to the 1990s. Two theory strands are offered: a semiotic view related to Peirce and Wittgenstein (presented by Willibald Dörfler), and the theory of learning activity by Joachim Lompscher (presented by Regina Bruder and Oliver Schmitt). By networking the two theoretical approaches in a case study of learning fractions, it clarifies the nature of the two theories, how they can be related to inform practice and renew TME-issues for mathematics education as a scientific discipline.
Theoretical Aspects of Transition Metal Catalysis
This volume, organized into eight chapters written by leading scientists in the field, illustrates the progress made during the last decade. The reader will obtain a deep insight into the present state of quantum chemical research in transition metal catalysis. Transition metal catalysis belongs to the most important chemical research areas because a ubiquitous number of chemical reactions are catalyzed by transition metal compounds. Many efforts are being made by industry and academia to find new and more efficient catalysts for chemical processes. Transition metals play a prominent role in catalytic research because they have been proven to show an enormous diversity in lowering the activation barrier for chemical reactions.
Theoretical Aspects of Local Search
Local search has been applied successfully to a diverse collection of optimization problems. It's appreciated for its basic conceptual foundation, its general applicability, and its power to serve as a source for new search paradigms. The typical characteristics of combinatorial optimization problems to which local search can be applied, its relation to complexity theory, and the combination with randomized search features have led to a wealth of interesting theoretical results. However, these results are scattered throughout the literature. This is the first book that presents a large collection of theoretical results in a consistent manner, thus providing the reader with a coherent overview of the achievements obtained so far, but also serving as a source of inspiration for the development of novel results in the challenging field of local search.
The Welfare of Sheep
The book begins with a discussion of current welfare thinking and how this might be relevant to sheep husbandry. The adaptations of wild sheep to diverse environments, and how their behaviour and physiology has developed to deal with these conditions is described and compared to conditions in modern sheep husbandry. The varied welfare demands of disease, nutrition and metabolism, farming systems and management practices are then discussed by specialists in those areas. The book concludes by considering the economics of improved welfare, and by describing breeding goals and new challenges and opportunities for good sheep husbandry. This book will be of interest to students and academics in animal welfare, animal production, and veterinary medicine, and those with a particular interest in or concern for sheep.
The Vehicle Routing Problem : Latest Advances and New Challenges
The Vehicle Routing Problem (VRP) has been an especially active and fertile area of research. Over the past five to seven years, there have been numerous technological advances and exciting challenges that are of considerable interest to students, teachers, and researchers. The Vehicle Routing Problem: Latest Advances and New Challenges will focus on a host of significant technical advances that have evolved over the past few years for modeling and solving vehicle routing problems and variants. New approaches for solving VRPs have been developed from important methodological advances. These developments have resulted in faster solution algorithms, more accurate techniques, and an improvement in the ability to solve large-scale, complex problems.
The Urban Mosaic of Post-Socialist Europe : Space, Institutions and Policy
The book explores urban dynamics in post-socialist Europe 15 years after the fall of communism. The ‘urban mosaic’ metaphor expresses the complexity, diversity and uniqueness of the processes and spatial outcomes in post-socialist cities. The book examines the urban development and the policy and planning processes that have resulted from the socio-economic, political, and institutional transformations characterizing the move to markets and democracy.
The Teleological and Kalam Cosmological Arguments Revisited
This book moves the discussion ahead in a significant way by devising an original deductive formulation of the Teleological Argument (TA) which demonstrates that the following are the only possible categories of hypotheses concerning fine-tuning and order: (i) chance, (ii) regularity, (iii) combinations of regularity and chance, (iv) uncaused, and (v) design. This book also demonstrates that there are essential features of each category such that, while the alternatives to design are unlikely, the Design Hypothesis is not, and that one can argue for design by exclusion without having to first assign a prior probability for design.
The Structure and Function of Plastids
Provides a comprehensive look at the biology of plastids, the multifunctional biosynthetic factories that are unique to plants and algae. The book is divided into five sections: (I): Plastid Origin and Development; (II): The Plastid Genome and Its Interaction with the Nuclear Genome; (III): Photosynthetic Metabolism in Plastids; (IV): Non-Photosynthetic Metabolism in Plastids; (V): Plastid Differentiation and Response to Environmental Factors. Each chapter includes an integrated view of plant biology from the standpoint of the plastid.
The Sphere of Attention : Context and Margin
The phone call came mid-afternoon in February of 1996. The program chair for the annual meeting for the Southern Society of Philosophy and Psychology wanted to make sure he had the facts right. “This is somewhat unusual…” he began. “You’re a philosophy professor who wants to present to psychologists in the psychology portion of the meeting.” “That’s right.” “Well your paper was accepted for that part of the program but the others just wanted me to check and make sure that’s where you want to be presenting.” “That’s right.” Reassured, the professor wished me luck and said good-bye. In my session at the meeting, I was the last to present. As my time approached, the medium-sized room slowly became crowded. I dreamed that these psychologists had left their other meetings early to make sure to catch my presentation on the use of metaphors in attention research. As I arose to present I noticed that the half-full room had become standing room only! Finally, after years of feeling as if I was struggling alone in promoting and defending a phenomenology of attention, I had an eager audience for my message. My persistence had paid off. I delivered my message with passion.
The Social Metabolism of Spanish Agriculture, 1900–2008 : The Mediterranean Way Towards Industrialization
Provides a panoramic view of the evolution of Spanish agriculture from 1900 to the present, offering a more diverse picture to the complex and multidimensional reality of agrarian production.
The Seventeen Provers of the World : Foreword by Dana S. Scott
Commemorating the 50th anniversary of the first time a mathematical theorem was proven by a computer system, Freek Wiedijk initiated the present book in 2004 by inviting formalizations of a proof of the irrationality of the square root of two from scientists using various theorem proving systems. The 17 systems included in this volume are among the most relevant ones for the formalization of mathematics. The systems are showcased by presentation of the formalized proof and a description in the form of answers to a standard questionnaire. The 17 systems presented are HOL, Mizar, PVS, Coq, Otter/Ivy, Isabelle/Isar, Alfa/Agda, ACL2, PhoX, IMPS, Metamath, Theorema, Leog, Nuprl, Omega, B method, and Minlog.
The Semantic Web: Research and Applications ; Vol. 4011 ; 3rd European Semantic Web Conference, ESWC 2006, Budva, Montenegro, June 11-14, 2006, Proceedings
"PrefaceThis volume contains the main proceedings of the 3rd Annual European Se-mantic Web Conference (ESWC 2006) held in Budva, Montenegro, June 11-14,2006. ESWC 2006 showcased the latest results in research and application of Se-mantic Web technologies – moving us closer to the vision of creating a machineinterpretable web.Following the success of the previous conferences, it ensured that only papers of thehighest quality were accepted. The final acceptance of 48 papers for publicationand presentation at the conference out of the 181 submissions resulted in anacceptance rate of 26%."
The Semantic Web ; 3rd Asian Semantic Web Conference, ASWC 2008, Bangkok, Thailand, December 8-11, 2008. Proceedings.
Address the latest results in the research and applications of Semantic Web technologies and cover topics including: scalable reasoning and logic, ontology mapping, ontology modelling and management, ontologies and tags, human language technologies and machine learning, querying, semantic Web services and semantic Web applications.
The semantic web : Research and applications ; Vol. 3532 ; 2nd European Semantic Web Conference, ESWC 2005, Heraklion, Crete, Greece, May 29--June 1, 2005, Proceedings
The vision of the Semantic Web is to enhance today’s Web via the exploi- tion of machine-processable metadata. The explicit representation of the sem- tics of data, accompanied with domain theories (ontologies), will enable a web that provides a qualitatively new level of service. It will weave together an - crediblylargenetworkofhumanknowledgeandwillcomplementitwithmachine processability. Various automated services will help the user to achieve goals by accessing and providing information in a machine-understandable form. This process may ultimately create extremely knowledgeable systems with various specialized reasoning services systems. Many technologies and methodologies are being developed within arti?cial intelligence, human language technology, machine learning, databases, software engineering and information systems that can contribute to the realization of this vision.
