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Integral Methods in Science and Engineering : Theoretical and Practical Aspects

The quantitative and qualitative study of the physical world makes use of many mathematical models governed by a great diversity of ordinary, partial differential, integral, and integro-differential equations. An essential step in such investigations is the solution of these types of equations, which sometimes can be performed analytically, while at other times only numerically. This edited, self-contained volume presents a series of state-of-the-art analytic and numerical methods of solution constructed for important problems arising in science and engineering, all based on the powerful operation of (exact or approximate) integration.It covers a wide variety of topics, from the theoretical development of boundary integral methods to the application of integration-based analytic and numerical techniques that include integral equations, finite and boundary elements, conservation laws, hybrid approaches, and other procedures.

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Inorganic Constituents in Soil : Basics and Visuals

A must-read for students of and beginners in soil science. In a well-organized and easy-to-follow manner, it provides basic outlines of soil minerals, new methods and recent developments in the field, with a special focus on visual aids. The chapters on primary minerals, secondary minerals, non-crystalline inorganic constituents and inorganic constituents sensitive to varying redox conditions will help readers understand the basic components of soils. Further, readers are introduced to new analytical methods with the aid of microscopy and recent developments in the field. Uniquely, the book features case studies on the identification and isolation methods for vivianite crystals from paddy field soils, as well as a identical procedure for identifying noncrystalline constituents such as volcanic glasses and plant opals, which can also be applied to other soils depending on the local conditions.

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Innovation Policy in a Knowledge-Based Economy : Theory and Practice

Why Analyze Innovation Policies From a Knowledge- Based Perspective? It is broadly accepted that we have moved (or are moving) to a knowled- based economy, characterized at least by two main features: that knowl­ edge is a major factor in economic growth, and innovation processes are systemic by nature. It is not surprising that this change in the economic paradigm requires new analytical foundations for innovation policies. One of the purposes of this book is to make suggestions as to what they should include. Underpinning all the chapters in this book is a conviction of the impor­ tance of dynamic and systemic approaches to innovation policy. Nelson and Arrow saw innovation and the creation of new knowl­ edge as the emergence and the diffusion of new information, characterized essentially as a public good. The more recent theoretical literature regarded the rationale for innovation policies as being to provide solutions to "mar­ ket failures". Today, however, knowledge is seen as multidimensional (tacit vs. codified) and open to interpretation. Acknowledging that the creation, coordination and diffusion of knowledge are dynamic and cumu­ lative processes, and that innovation processes result from the coordination of distributed knowledge, renders the "market failure" view of innovation policies obsolete. Innovation policies must be systemic and dynamic

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Information theory and machine learning

The recent successes of machine learning, especially regarding systems based on deep neural networks, have encouraged further research activities and raised a new set of challenges in understanding and designing complex machine learning algorithms. New applications require learning algorithms to be distributed, have transferable learning results, use computation resources efficiently, convergence quickly on online settings, have performance guarantees, satisfy fairness or privacy constraints, incorporate domain knowledge on model structures, etc. A new wave of developments in statistical learning theory and information theory has set out to address these challenges.

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Immunogenetics of Autoimmune Disease

Utoimmunity is the downstream outcome of a rather extensive and coordinated series of events that include loss of self-tolerance, peripheral lymphocyte Aactivation, disruption of the blood-systems barriers, cellular infiltration into the target organs and local inflammation. Cytokines, adhesion molecules, growth factors, antibodies, and other molecules induce and regulate critical cell functions that perpetuate inflammation, leading to tissue injury and clinical phenotype. The nature and intensity of this response as well as the physiological ability to restore homeostasis are to a large extent conditioned by the unique amino acid sequences that define allelic variants on each of the numerous participating mol­ ecules. Therefore, the coding genes in their germline configuration play a primary role in determining who is at risk for developing such disorders, how the disease progresses, and how someone responds to therapy. Although genetic components in these diseases are clearly present, the lack of obvious and homogeneous modes of transmission has slowed progress by prevent­ ing the full exploitation of classical genetic epidemiologic techniques. Furthermore, autoimmune diseases are characterized by modest disease risk heritability and m- tifaceted interactions with environmental influences. Yet, several recent discoveries have dramatically changed our ability to examine genetic variation as it relates to human disease. In addition to the development of large-scale laboratory methods and tools to efficiently recognize and catalog DNA diversity, over the past few years there has been real progress in the application of new analytical and data-manage­ ment approaches

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Immobilisation of DNA on Chips II

DNA chips are gaining increasing importance in different fields ranging from medicine to analytical chemistry with applications in the latter in food safety and food quality issues as well as in environmental protection. In the medical field, DNA chips are frequently used in arrays for gene expression studies to identify diseased cells due to over- or under-expression of certain genes, to follow the response of drug treatments, or to grade cancers), for genotyping of individuals, for the detection of single nucleotide polymorphisms, point mutations, and short tandem reports, or moreover for genome and transcriptome analyses in the quasi post-genomic sequencing era. Furthermore, due to some unique properties of DNA molecules, self-assembled layers of DNA are promising candidates in the field of molecular electronics.the main focus of these two volumes is on the immobilization chemistry, considering the various aspects of the immobilization process itself, since different types of nucleic acids, support materials, surface activation chemistries and patterning tools are of key concern.

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Imaging Technologies and Transdermal Delivery in Skin Disorders

This important, timely book covers the latest understanding about today's major skin disorders, the development of imaging technologies for skin diagnosis, and the applications of micro/nano-technologies for the treatment of skin complications. It also places great emphasis on the critical role that interdisciplinary science occupies to achieve the requisite level of understanding of skin conditions and their management, which is essential to creating technologies that work.

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Hydropower Economics

HYDROPOWER ECONOMICS examines sustainable alternate energy sources beginning with modeling hydropower and extending the model to include thermal power and wind power. The book will use various econometric measures, equilibrium metrics, OR methods, and DEA/productivity analyses to analyze and model the optimal use of these alternate energy sources. Because these problems are dynamic in nature, dynamic methods are used to model the problems. The book derives results on the allocation of the amounts of alternate sources of energy (water, thermal, and wind) required to produce electricity at acceptable levels over time. Graphic illustrations of the analytical and mathematical modeling used to reach research conclusions are used throughout the book.

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Homotopy-Based Methods in Water Engineering

Exploring the concept of homotopy from topology, different kinds of homotopy-based methods have been proposed for analytically solving nonlinear differential equations, given by approximate series solutions. Homotopy-Based Methods in Water Engineering attempts to present the wide applicability of these methods to water engineering problems. It solves all kinds of nonlinear equations, namely algebraic/transcendental equations, ordinary differential equations (ODEs), systems of ODEs, partial differential equations (PDEs), system of PDEs, and integro-differential equations using the homotopy-based methods

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Heat Conduction : Mathematical Models and Analytical Solutions

Many phenomena in social, natural and engineering fields are governed by wave, potential, parabolic heat-conduction, hyperbolic heat-conduction and dual-phase-lagging heat-conduction equations. The focus of the present monograph is on these equations: their solution structures, methods of finding their solutions under various supplementary conditions, as well as the physical implication and applications of their solutions.

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Health Care Benchmarking and Performance Evaluation : An Assessment using Data Envelopment Analysis (DEA)

One of the most pressing problems in today's health care system is performance evaluation. Performance evaluation in health care goes well beyond financial and efficiently issues directly to matters of life and death. HEALTH CARE BENCHMARKING AND PERFORMANCE EVALUATION applies the analytical framework of Data Envelopment Analysis methodology to provide health care administrators with specific benchmarking tools for performance evaluation. Most importantly, the book provides health care practitioners and administrators with information of what is lacking in specific aspects of performance and then outlines the ways how these performance inadequacies can be improved.

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Handbook on Decision Support Systems 1 : Basic Themes

Decision support systems have experienced a marked increase in attention and importance over the past 25 years. The aim of this book is to survey the decision support system (DSS) field – covering both developed territory and emergent frontiers. It will give the reader a clear understanding of fundamental DSS concepts, methods, technologies, trends, and issues. It will serve as a basic reference work for DSS research, practice, and instruction. To achieve these goals, the book has been designed according to a ten-part structure, divided in two volumes with chapters authored by well-known, well-versed scholars and practitioners from the DSS community.

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Handbook of soil analysis : Mineralogical, organic and inorganic methods

This new book by Marc Pansu and Jacques Gautheyrou provides a synopsis of the analytical procedures for the physicochemical analysis of soils. It is written to conform to analytical standards and quality control. It focuses on mineralogical, organic and inorganic analyses, but also describes physical methods when these are a precondition for analysis. It will help a range of different users to choose the most appropriate method for the type of material and the particular problems they have to face. The compiled work is the product of the experience gained by the authors in the laboratories of the Institute of Research for Development (IRD) in France and in tropical countries, and includes an extensive review of the literature. The reference section at the end of each chapter lists source data from pioneer studies right up to current works, such as, proposals for structural models of humic molecules, and itself represents a valuable source of information.

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Handbook of Practical X-Ray Fluorescence Analysis

X-Ray Fluorescence analysis (XRF) is a reliable multi-elemental and nondestructive analytical method widely used in research and industrial applications. This practical handbook provides self-contained modules featuring XRF instrumentation, quantification methods, and most of the current applications. The book gives a survey of the theoretical fundamentals, analytical instrumentation, software for data processing, various excitation regimes including gracing incidents and microfocus measurements, quantitative analysis, applications in routine and micro analysis, mineralogy, biology, medicine, criminal investigations, archeology, metallurgy, abrasion, microelectronics, environmental air and water analysis. It gives the basic knowledge on this technique, information on analytical equipment and guides the reader to the various applications.

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Handbook of pharmaceutical wet granulation : Theory and practice in a quality by design paradigm

Handbook of Pharmaceutical Wet Granulation: Theory and Practice in a Quality by Design Paradigm offers a single and comprehensive reference dedicated to all aspects of pharmaceutical wet granulation, taking a holistic approach by combining introductory principles with practical solutions. Chapters are written by international experts across industry, academic and regulatory settings, and cover a wide spectrum of relevant and contemporary wet granulation topics, techniques and processes. The books' focus on process analytical technology, quality by design principles, granulation equipment, modeling, scale-up, control and real time release makes it a timely and valuable resource for all those involved in pharmaceutical wet granulation.

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Handbook of modern sensors. physics, designs, and applications

Presents a comprehensive and up-to-date account of the theory (physical principles), design, and practical implementations of various sensors for scientific, industrial, and consumer applications. This latest edition focuses on the sensing technologies driven by the expanding use of sensors in mobile devices. These new miniature sensors will be described, with an emphasis on smart sensors which have embedded processing systems. The chapter on chemical sensors has also been expanded to present the latest developments.

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Handbook of marketing analytics : Methods and applications in marketing management, public policy, and litigation support

Shows analytical marketing methods and their high-impact real-life applications in marketing management, Public policy, and litigation support. Fourteen chapters present an overview of specific marketing analytic methods in technical detail, While 22 case studies present thorough examples of the use of each method. Multidisciplinary in scope, This handbook covers experimental methods, non-experimental methods, and their digital-era extensions. It explores topics such as : Classical and bayesian econometrics, Causality, Machine learning, Optimization, And recent advancements in conjoint analysis.

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Handbook of high field dynamic nuclear polarization

This comprehensive handbook is a compendium of the current state-of-the art of high field Dynamic Nuclear Polarization—from long-proven, early developments, up to today’s hot topics. It covers all the relevant subjects that have made a direct or indirect contribution toward advancing this field, and focuses on topics such as: the theory behind the effects seen within DNP; instrumentation required for carrying out DNP; and specific applications of DNP including protein monitoring, catalysis, nanoparticles, biological and clinical studies.

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Handbook of Drug Monitoring Methods : Therapeutics and Drugs of Abuse

In Handbook of Drug Monitoring Methods: Therapeutics and Drug Abuse, authors discuss the different analytical techniques used in today’s practice of therapeutic drug monitoring and drugs of abuse as well as alcohol testing with relevant theory, mechanism, and in-depth scientific discussion on each topic.

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Halogen bonding : Fundamentals and applications

The articles in this volume specifically address halogen bonding, and two aspects of it … . The contributions to this volume are reasonably up-to-date … . each chapter begins with a detailed table of contents and most of them also provide a list defining abbreviations. In summary, this is a very useful book that contains a great deal of information.

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