Page 38
Page 38
Photomorphogenesis in plants and bacteria : Function and signal transduction mechanisms
Plants as sessile organisms have evolved fascinating capacities to adapt to changes in their natural environment. Arguably, light is by far the most important and variable environmental factor. The quality, quantity, direction and duration of light is monitored by a series of photoreceptors covering spectral information from UVB to near infrared. The response of the plants to light is called photomorphogenesis and it is regulated by the concerted action of photoreceptors. The combined techniques of action spectroscopy and biochemistry allowed one of the important photoreceptors – phytochrome – to be identified in the middle of the last century.
Photobiology : The Science of Life and Light
The book starts with the physics and chemistry of light, and how to handle light in the laboratory and measure it in the field, the properties of daylight, and new uses of light in research. It deals with the evolution of photosynthesis and with the mechanisms of its primary steps. Four chapters deal with how organisms use light for their orientation in space and time: the biological clock and its resetting by light, the light-dependent magnetic compass, and photoperiodism in animals and plants. There are also several medically oriented chapters and two chapters specifically aimed at the photobiology educator.
Philosophys Higher Education
In sociology it was the dualism of the individual and society. The question most asked in our classes was always regarding which aspect of the dualism dominated the other. The answer we always leaned towards was that both were mutually affected by the other. The answer seemed to lie somewhere in the middle. It was only at university, first as an undergraduate and then as a postgraduate, that I came across the idea of the dialectic. Slowly I began to recognise that the dualisms which plagued social theory—I and we, self and other, good and evil, modernity and post-modernity, autonomy and heteronomy, freedom and nature, truth and relativism, and so many more—were not only dialectical in being thought about, but also that the thought of them being dialectical had an even stranger quality. It was the same experience as being at school.
Philosophy, Science, Education and Culture
Currents such as epistemological and social constructivism, postmodernism, and certain forms of multiculturalism that had become fashionable within science education circles in the last decades lost sight of critical inquiry as the core aim of education. In this book we develop an account of education that places critical inquiry at the core of education in general and science education in particular. Since science constitutes the paradigm example of critical inquiry, we explain the nature of science, paying particular attention to scientific methodology and scientific modeling and at the same time showing their relevance in the science classroom. We defend a universalist, rationalist, and objectivist account of science against epistemological and social constructivist views, postmodernist approaches and epistemic multiculturalist accounts.
Philosophy of race : An introduction
Philosophy of Race: An Introduction provides plainly written access to a new subfield that has been in the background of philosophy since Plato and Aristotle. Part I provides an overview of ideas of race and ethnicity in the philosophical canon, egalitarian traditions, race in biology, and race in American and Continental Philosophy. Part II addresses race as it operates in life through colonialism and development, social constructions and institutions, racism, political philosophy, and gender. This book constructs an outline that will serve as a resource for students, nonspecialists, and general readers in thinking, talking, and writing about philosophy of race.
Philosophy of Chemistry : Synthesis of a New Discipline
This comprehensive volume marks a new standard in scholarship in the still emerging field of the philosophy of chemistry. With selections drawn from a wide range of scholarly disciplines, philosophers, chemists, and historians of science here converge to ask some of the most fundamental questions about the relationship between philosophy and chemistry. What can chemistry teach us about longstanding disputes in the philosophy of science over such issues as reductionism, autonomy, and supervenience? And what new issues may chemistry bring to the forefront now that it has joined physics and biology as a serious topic for philosophical reflection.
Philosophy and Religion in German Idealism
This book contains the selected proceedings of a conference on Religion in German Idealism which took place in Nij- gen (Netherlands) in January 2000. The conference was - ganized by the Centre of German Idealism, which co-or- nates the research on classical German philosophy in the Netherlands and in Belgium. Generous support of the Dutch Organisation for Scientific Research (NWO) has made this conference possible. A few months after the conference Ludwig died, and this circumstance unexpectedly delayed efforts to bring the proceedings of the conference to p- lished form. We are now happy to present those proce- ings, dedicated to the memory of the founding father of the Centre.
Philosophical Lectures on Probability
Philosophical Lectures on Probability contains the transcription of a series of lectures held by Bruno de Finetti (one of the fathers of subjective Bayesianism) and collected by the editor Alberto Mura at the Institute for Advanced Mathematics in Rome in 1979. The book offers a live in-context outlook on de Finetti’s later philosophy of probability. On several points de Finetti’s remarks revise widespread interpretations of his thought and reveal to be topical in the light of recent developments. The book is enriched by an essay of Maria Carla Galavotti, introducing de Finetti’s philosophy of probability as well as biographical essential information. Moreover, it contains more than 180 editor’s notes, aimed at helping the reader to properly appreciate de Finetti’s thought and its impact on recent philosophical developments about probability.
Phenomenology of Life. Meeting the Challenges of the Present-Day World
Philosophy has been always received or bypassed for its resonance or aloofness with the spirit of the time. Should not philosophy/phenomenology of life be expected to do more to ascertain its validity? Should it not pass the pragmatic test, that is to respond directly to the life-concerns of its time? What is the role of the philosopher and philosophy today? Due to the ever-advancing scientific, technological, social and cultural changes that are shaping human life and the life-world-in-transformation, we are desperately seeking a measure to estimate life's unfolding, a compass to stir the course between Scylla and Charibda to maintain human-hood and creative insight for laying the cornerstones for the unforeseeable unfolding of life dynamisms. It is this challenge which philosophy/phenomenology of life meets with underlying ontopoietic unraveling of the hidden logoic concatenations of beingness-in-becoming.
Phenomenology of life - From the animal Soul to the human mind ; Book I : In search of experience
Transcendental phenomenology presumed to have overcome the classic mind-body dichotomy in terms of consciousness, yet, according to progress in scientific studies, the biological functions of the brain seem to appropriate significant functions attributed traditionally to consciousness. Should we indeed dissolve the specificity of human consciousness by explaining human experience in its multiple sense-giving modalities through the physiological functions of the brain? The present collection of studies addresses this crucial question challenging such "naturalizing" reductionism from multiple angles.
Phénoménologie de la religion et herméneutique théologique dans la pensée du jeune Heidegger : Commentaire analytique des Fondements philosophiques de la mystique médiévale (1916-1919) = Phenomenology of religion and theological hermeneutics in the thought of the young Heidegger : Analytical commentary on the Philosophical Foundations of Medieval Mysticism (1916-1919)
Deals with the unknown from Heidegger's texts (Philosophical Bases of Medieval Mysticism) to many scholars / Gives the first in-depth interpretation of the text mentioned above - which, moreover, is not translated into French however - in all languages / Connects two goals: reconstructing Heidegger's early phenomenology of religion but also trying to propose a new kind of phenomenology of religion outside of Heidegger / Not a single comment, but also a real essay in religious phenomenology / Shows how Heidegger's early phenomenology of religion is compatible with a specific theological hermeneutics; thus making Heidegger's thought useful for further-philosophical research such as theology and "Religionswissenschaft"
Phenolic Compound Biochemistry
This book is written for researchers, instructors, advanced undergraduate students and beginning graduate students in the life sciences who wish to become more familiar with these and many other intriguing aspects of phenolic compounds. Topics covered include nomenclature, chemical properties, biosynthesis, including an up-to-date overview of the genetics controlling phenolic metabolism, isolation and characterization of phenolic compounds, phenolics used in plant defense, and the impact of phenolics on human health. The book is written in an accessible style, and assumes only basic knowledge of organic chemistry, biochemistry and cell physiology. More than 300 chemical structures and reaction schemes illustrate the text.
Phase Resetting in Medicine and Biology : Stochastic Modelling and Data Analysis
Presents a new theoretical approach to phase resetting and stimulation-induced synchronization and desynchronization in a population of oscillators. The author uses stochastic methods from statistical mechanics and applies his theory to models of practical importance in physiology and neuroscience. He makes the book accessible to readers not familiar with the mathematical formalism. The results are presented and additionally explained without formulae, particularly with a view to the interests of neuroscientists. The author also proposes improvements to stimulation techniques as used by neurologists and neurosurgeons in the context of Parkinson's disease and MEG/EEG data analysis. The book is written for researchers and graduate students but it can also benefit medical practitioners.
Pharmacology of immunotherapeutic drugs
Focus on pharmacology and mechanisms of immunotherapeutic agents in various immune disorders / Includes a comprehensive table of drug classes that affect the immune system / Chapters feature novel case studies with practice questions / Bench to Bedside" sections describe the discovery and clinical investigation of several therapies regulating immune system function / The Pharmacology of Immunotherapeutic Drugs is a reference for immunologists and clinicians (medical doctors, pharmacists, nurses) examining the modulation of inflammatory processes by a variety of medications targeting the cells and mediators of our immune system.
Pharmacology of Immunosuppression
Provides a guide and detailed review of immunosuppression in terms of molecular mechanisms of action, side effects and clinical trials that validated their utility. This includes their use in solid organ transplantation, bone marrow transplantation and autoimmune diseases and inflammatory diseases. This book is a critical review of these topics and a vital resource. Provides all information on clinical and basic aspects of immunosuppression and its role in a variety of diseases. State of the art information by leaders in the field.
Pharmacology of antifungal agents
Fungal infections are associated with significant morbidity and mortality, and their management is restricted to a variety of agents from five established classes of antifungal medication. In practice, existing antifungal agents are often constrained by dose-limiting toxicities, drug interactions, and the routes of administration. An increasing prevalence of fungal infections along with rising rates of resistance and the practical limitations of existing agents has created a demand for the development of new antifungals, particularly those with novel mechanisms of action. This article reviews antifungal agents currently in various stages of clinical development. In addition to systemic and superficial fungal diseases.
Pharmacology in drug discovery and development : Understanding drug response
An introductory resource illustrating how pharmacology can be used to furnish the tools necessary to analyze different drug behavior and trace this behavior to its root cause or molecular mechanism of action. The concepts discussed in this book allow for the application of more predictive pharmacological procedures aimed at increasing therapeutic efficacy that will lead to more successful drug development. Chapters logically build upon one another to show how to characterize the pharmacology of any given molecule and allow for more informed predictions of drug effects in all biological systems. New chapters are dedicated to the interdisciplinary drug discovery environment in both industry and academia, and special techniques involved in new drug screening and lead optimization. This edition has been fully revised to address the latest advances and research related to real time kinetic assays, pluridimensional efficacy, signaling bias, irreversible and chemical antagonism, allosterically-induced bias, pharmacokinetics and safety, target and pathway validation, and much more.
Pharmacological Mechanisms in Alzheimers Therapeutics
Alzheimer’s is the most common dementia in the elderly. The need for effective therapy of dementia is greater than ever, but there is not, as yet, a drug therapy which can stop or reverse the clinical consequences. The book should be of interest to medical professionals and basic scientists alike since it provides ideas about current trends in Alzheimer’s therapeutics to the general public.
Pharmacokinetics and toxicokinetic considerations - Vol II ; 1st ed.
Explains the central principles, cutting-edge methodologies, and incipient thought processes applied to toxicology research. As part of the Advances in Pharmaceutical Product Development and Research series, the book provides expert literature on dose, dosage regimen and dose adjustment, medication errors, and approaches for its prevention, the concept of pharmacotherapy, and managed care in clinical interventions. It expounds on strategies to revamp the pharmacokinetics of the drug and the factors affecting the stability of drugs and their metabolites in biological matrices. Finally, the book offers focused elaborations on various bioanalytical methods for bioavailability and bioequivalence assessment and integrates the wide-ranging principles and concepts shared by toxicokinetics and pharmacodynamics as mutual crosstalk rather than isolated observations. It will be helpful to researchers and advanced students working in the pharmaceutical, cosmetics, biotechnology, food, and related industries including toxicologists, pharmacists, and pharmacologists.
Pharmacokinetics : Basics to applications
Covers all the essential elements of pharmacokinetics, from basics to applications. It describes authoritative equations and methods on pharmacokinetic evaluation procedures with their importance. Each chapter of the book is supplemented with numerous illustrations and figures for easy understanding of the subject.
