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Aspects of mathematical modelling : Applications in science, medicine, economics and management
The construction of mathematical models is an essential scientific activity. Mathematics has long been associated with developments in the exact sciences and engineering, but more recently mathematical modelling has been used to investigate complex systems that arise in many other fields. The contributors to this book demonstrate the application of mathematics to modern research topics in ecology and environmental science, health and medicine, phylogenetics and neural networks, theoretical chemistry, economics and management. The reader will find some review papers outlining current research directions in hot topics such as pattern formation and applications to medicine, and more targeted research papers on current developments in the various disciplines included.
Aspects of Illegal, Unreported and Unregulated Fishing in the Southern Ocean
Overfishing threatens the viability of high seas living resources. Furthermore, controls to prevent overfishing are inadequate. Illegal, Unreported and Unregulated (IUU) fishing is a product of overfishing and affects all marine fisheries. Southern Ocean fisheries have been particularly targeted by IUU fishing. The efforts of the Convention for the Conservation of Antarctic Marine Living Resources Commission and the Australian government to adopt complementary measures to deter IUU fishing in the Southern Ocean form the basis of this study, although the examination is conducted following a comprehensive review of the legal and other factors contributing to the development of IUU fishing as well as the applicable international law.
Ascochyta blights of grain legumes
Ascochyta blights consistently affect large areas of grain legume production (pea, lentil, chickpea and faba bean) in all countries where they are cultivated. These diseases are capable of causing large yield losses under conducive environmental conditions. This book considers the state of the art by taking a comparative approach of Ascochyta blight diseases of cool season food and feed legumes. Topics considered are pathogen diversity, legume genetics and breeding, and integrated disease management.
Arts and health promotion : Tools and bridges for practice, research, and social transformation
This book offers an overview of the beautiful, powerful, and dynamic array of opportunities to promote health through the arts from theoretical, methodological, pedagogical, and critical perspectives. This is the first-known text to connect the disparate inter-disciplinary literatures into a coherent volume for health promotion practitioners, researchers, and teachers. It provides a one-stop depository for using the arts as tools for health promotion in many settings and as bridges across communities, cultures, and sectors.
Artificial intelligence and machine learning in health care and medical sciences : Best practices and pitfalls
Provides a detailed review of the latest methods and applications of artificial intelligence (AI) and machine learning (ML) in medicine. With chapters focusing on enabling the reader to develop a thorough understanding of the key concepts in these subject areas along with a range of methods and resulting models that can be utilized to solve healthcare problems, the use of causal and predictive models are comprehensively discussed. Care is taken to systematically describe the concepts to facilitate the reader in developing a thorough conceptual understanding of how different methods and resulting models function and how these relate to their applicability to various issues in health care and medical sciences. Guidance is also given on how to avoid pitfalls that can be encountered on a day-to-day basis and stratify potential clinical risks.
Artificial intelligence : A modern approach ; global ed.
Explores the full breadth and depth of the field of artificial intelligence (AI). The 4th edition brings readers up to date on the latest technologies, presents concepts in a more unified manner, and offers new or expanded coverage of machine learning, deep learning, transfer learning, multi agent systems, robotics, natural language processing, causality, probabilistic programming, privacy, fairness, and safe AI
Artificial immune systems ; Vol. 3627 ; 4th International conference, ICARIS 2005, Banff, Alberta, Canada, August 14-17, 2005, Proceedings
Your immune system is unique. It is in many ways as complex as your brain, butit is not centred in one location, like the brain. It is not a single organ—it consistsof many different cell types, diverse methods of intercellular communication, andmany different organs. Its functionality is blurred throughout you—we can’textract the immune system, or point to where it begins and ends. The immunesystem is not separable from the system it protects. It has integral links to everyorgan of our bodies.This has radical implications for the field of Artificial Immune Systems (AIS),that we are only now beginning to comprehend. One of the first insights is thatmodelling the immune system, or developing any kind of immune algorithm, isdifficult. The immune system is one aspect of biology that we find difficult toapply simple reductionist explanations to. We can very successfully extract sub-processes of the whole and create immune algorithms based on those processes.
Artificial immune systems ; 7th International Conference, ICARIS 2008, Phuket, Thailand, August 10-13, 2008. Proceedings
This book constitutes the refereed proceedings of the 7th International Conference on Artificial Immune Systems, ICARIS 2008, held in Phuket, Thailand, in August 2008.
Articulated Motion and Doformable Objects ; 4th International Conference, AMDO 2006, Port d'Andratx, Mallorca, Spain, July 11-14, 2006, Proceedings
The subject of the conference was ongoing research in articulated motionon a sequence of images and sophisticated models for deformable objects. Thegoals of these areas are to understand and interpret the motion of complexobjects that can be found in sequences of images in the real world. The maintopics considered as priority were: geometric and physical deformable models,motion analysis, articulated models and animation, modelling and visualizationof deformable models, deformable models applications, motion analysis applica-tions, single or multiple human motion analysis and synthesis, face modelling,tracking, recovering and recognition models, virtual and augmentedreality, haptics devices, biometrics techniques.
Articulated motion and deformable objects ; 5th International Conference, AMDO 2008, Port d’Andratx, Mallorca, Spain, July 9-11, 2008. Proceedings
This book constitutes the refereed proceedings of the 5th International Conference on Articulated Motion and Deformable Objects, AMDO 2008, held in Port d'Andratx, Mallorca, Spain, in July 2008.
Aromatase Inhibitors
Many breast tumours are dependent upon oestrogen for their development and continued growth. Over the last 25 years hormone therapy has progressed from the irreversible destruction of endocrine glands to the use of drugs that reversibly suppress oestrogen synthesis or action. The inhibition of oestrogen synthesis is most readily achieved by inhibiting the final step in the pathway of oestrogen biosynthesis, the reaction which transforms androgens into oestrogens by creating an aromatic ring in the steroid molecule (hence the enzyme's trivial name, aromatase). Whereas the first aromatase inhibitors to be used therapeutically could be shown to produce drug-induced inhibition of the enzyme and therapeutic benefits in patients with breast cancer, they were not particularly potent and lacked specificity. However, second-generation drugs were developed and most recently third-generation inhibitors have evolved which possess remarkable specificity and potency. Initial results from clinical trials suggest that these agents will become the cornerstones of future endocrine therapy.
Aromatase Inhibitors
Many breast tumours are dependent upon oestrogen for their development and continued growth. Over the last 25 years hormone therapy has progressed from the irreversible destruction of endocrine glands to the use of drugs that reversibly suppress oestrogen synthesis or action. The inhibition of oestrogen synthesis is most readily achieved by inhibiting the final step in the pathway of oestrogen biosynthesis, the reaction which transforms androgens into oestrogens by creating an aromatic ring in the steroid molecule (hence the enzyme's trivial name, aromatase). Whereas the first aromatase inhibitors to be used therapeutically could be shown to produce drug-induced inhibition of the enzyme and therapeutic benefits in patients with breast cancer, they were not particularly potent and lacked specificity. However, second-generation drugs were developed and most recently third-generation inhibitors have evolved which possess remarkable specificity and potency. Initial results from clinical trials suggest that these agents will become the cornerstones of future endocrine therapy.
Arithmetical investigations : Representation theory, orthogonal polynomials, and quantum interpolations
In this volume the author further develops his philosophy of quantum interpolation between the real numbers and the p-adic numbers. The p-adic numbers contain the p-adic integers Zp which are the inverse limit of the finite rings Z/pn. This gives rise to a tree, and probability measures w on Zp correspond to Markov chains on this tree. From the tree structure one obtains special basis for the Hilbert space L2(Zp,w). The real analogue of the p-adic integers is the interval [-1,1], and a probability measure w on it gives rise to a special basis for L2([-1,1],w) - the orthogonal polynomials, and to a Markov chain on "finite approximations" of [-1,1]. For special (gamma and beta) measures there is a "quantum" or "q-analogue" Markov chain, and a special basis, that within certain limits yield the real and the p-adic theories. This idea can be generalized variously. In representation theory, it is the quantum general linear group GLn(q)that interpolates between the p-adic group GLn(Zp), and between its real (and complex) analogue -the orthogonal On (and unitary Un )groups. There is a similar quantum interpolation between the real and p-adic Fourier transform and between the real and p-adic (local unramified part of) Tate thesis, and Weil explicit sums.
Area-wide control of insect pests : From research to field implementation
This new textbook on area-wide control of insect pests collates a series of selected papers that attempts to address various funda- mental components of AW-IPM, e.g. the importance of relevant problem-solving research, the need for essential baseline data, thesignificanceofadequatetoolsforappropri-atecontrolstrategies,andthevalueofpilottri- als, etc.
Architectures of festival in early modern Europe : Fashioning and re-fashioning urban and courtly space
Draws on up-to-date research by a Europe-wide group of academic scholars and museum and gallery curators to provide a unique, intellectually-stimulating and beautifully-illustrated account of temporary architecture created for festivals of the sixteenth and seventeenth centuries, together with permanent architecture pressed into service for festival occasions across major European locations including Italian, French, Austrian, Scottish and German.
Approval Voting
The book proposes a compelling way to elect some 500,000 officials in public elections. After a generation of discussion and debate on the subject, the authors remain convinced that Approval Voting is as relevant today.
Appropriate Dose Selection - How to Optimize Clinical Drug Development
Optimal dose individualization has become more important in improving clinical efficacy and safety, given the variability in drug response, e.g., due to concurrent illnesses or co-medications. Therefore, the role of optimal dose finding in early clinical drug development so as to maximize successful clinical use is emphasized. The continued use of biomarkers – based on the (known) pharmacology of the drug and/or biology of the underlying disease – along with exposure–response evaluation throughout all phases of drug development can quantitatively integrate clinical pharmacology knowledge, provide early proof of concept, and help in rational dose selection and rational drug product labeling for clinical use.
Applied Spatial Data Analysis with R
Applied Spatial Data Analysis with R is divided into two basic parts, the first presenting R packages, functions, classes and methods for handling spatial data, The second part showcases more specialised kinds of spatial data analysis, including spatial point pattern analysis, interpolation and geostatistics, areal data analysis and disease mapping.
Applied Bioinformatics : An Introduction
In this book, anyone who can operate a PC, standard software and the Internet will learn to understand the biological basis of bioinformatics of the existence as well as the source and availability of bioinformatics software how to apply these tools and interpret results with confidence.This is aided by introductory chapters to important aspects of bioinformatics, detailed bioinformatics exercises, including solutions and a glossary of definitions and terminology relating to bioinformatics.
Applications of Membrane Computing
Membrane computing is a branch of natural computing which investigates computing models abstracted from the structure and functioning of living cells and from their interactions in tissues or higher-order biological structures. The models considered, called membrane systems (P systems), are parallel, distributed computing models, processing multisets of symbols in cell-like compartmental architectures. In many applications membrane systems have considerable advantages – among these are their inherently discrete nature, parallelism, transparency, scalability and nondeterminism.
