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In Vivo Imaging of Cancer Therapy
In Vivo Imaging of Cancer Therapy addresses a variety of cutting-edge imaging techniques, including their use for best practice, and provides examples of results found in both pre-clinical and clinical studies. This comprehensive text covers the entire spectrum of in vivo imaging for oncology, including current approaches to detailed anatomic measurements, MR and optical spectroscopy, and molecular imaging techniques requiring exogenously administered imaging agents. The challenges and approaches to quantification are also outlined. The authors describe technologies and methods that are currently clinically available, and many that are still in a developmental stage or useful only in animal studies.
In Vitro Drug Release Testing of Special Dosage Forms
Covers the in vitro release testing of: lipid based oral formulations; chewable oral drug products; injectables; drug eluting stents; inhalation products; transdermal formulations; topical formulations; vaginal and rectal delivery systems and ophthalmics. The book concludes with a look at regulatory aspects. Covers both oral and non-oral dosage forms Describes current regulatory conditions for in vitro drug release testing Features contributions from well respected global experts in dissolution testing
In Vitro Culture of Mycorrhizas
biologists have made important progress in understanding better the functioning of AM fungi. An in vitro technique has been developed using mycorrhizal root organ cultures, which made it possible to investigate the genetics, cell biology and physiology of AM fungi. We can now be objective enough to critically evaluate the impacts the in vitro technique has had to improve our knowledge on mycorrhizal symbiosis.
In sync with adolescence : The role of morningness-eveningness in development
At the start of every school day, it’s not an unfamiliar sight to see younger children bounding toward school, bright-eyed and bushy-tailed, ready to seize the day. In contrast, adolescents sometimes seem to sleepwalk toward their middle and high schools, often bleary-eyed, cantankerous, and less than enthusiastic to get down to work. Why the difference?
In Silico Immunology
"in silico Immunology" is a book for the future: it will summarize these emergent disciplines and, while focusing on cutting edge developments, will address the issue of synergy as it shows how these three are set to transform immunological science and the future of health care.
In Silico Dreams : How Artificial Intelligence and Biotechnology Will Create the Medicines of the Future
In Silico Dreams: How Artificial Intelligence and Biotechnology Will Create the Medicines of the Future delivers an illuminating and fresh perspective on the convergence of two powerful technologies: AI and biotech. Accomplished genomics expert, executive, and author Brian Hilbush offers readers a brilliant exploration of the most current work of pioneering tech giants and biotechnology startups who have already started disrupting healthcare.
In and Out of Equilibrium 2
The intersection of probability and physics has been a rich and explosive area of growth in the past three decades, specifically covering such subjects as percolation theory, random walks in random environment, disordered systems, interacting particle systems and their many connections to statistical mechanics. The last decade was particularly fruitful for all these topics. This book reflects this development and marks also the first decade of the Brazilian School of Probability. This volume consists of a collection of invited articles, written by some of the most distinguished probabilists, most of whom have been personally responsible for advances in the various subfields of probability.
Impulse Breakdown of Liquids
The book describes the main physical processes and phenomena in pulsed electric breakdown. The knowledge and the control of the electric breakdown of liquids is important not only for the insulation inside power systems but it is also used for the creation and information of high voltage and high current pulses. Such high-voltage micro- and nanosecond pulses find wide application in experimental physics, electro discharge technology, physics of dielectrics, radar detection and ranging, high-speed photography. The nature of charge carriers, mechanism of formation and evolution of the gas phase, and their role in charge ignition (initiation) and development are considered. In particular, the spatiotemporal laws of propagation and parameters of charge channels are described in detail and the boundery conditions of the breakdown initiation are formulated.
Improving image quality in visual cryptography
This book comprehensively covers the important efforts in improving the quality of images in visual cryptography (VC), with a focus on cases with gray scale images. It not only covers schemes in traditional VC and extended VC for binary secret images, but also the latest development in the analysis-by-synthesis approach.
Improving Health Care in Low- and Middle-Income Countries : A Case Book
This book is a collection of 12 case studies capturing decades of experience improving health care and outcomes in low- and middle-income countries. Each case study is written by healthcare managers and providers who have implemented health improvement projects using quality improvement methodology, with analysis from global health experts on the practical application of improvement methods.
Improvements in System Safety ; Proceedings of the Sixteenth Safety-critical Systems Symposium, Bristol, UK, 5-7 February 2008
Improvements in System Safety contains the full complement of papers presented at the sixteenth annual Safety-critical Systems Symposium, held at Bristol, UK, in February 2008.The Symposium is for engineers, managers and academics in the field of safety, across all industry sectors, and so the papers included in this volume offer a wide-ranging coverage of major safety issues as well as a good blend of academic research and industrial experience. They include discussions of some of the most recent developments in the field.
Implementing Strategic Environmental Assessment
More countries are now using Strategic Environmental Assessment (SEA) than ever before. This timely and comprehensive Handbook describes the implementation of SEA in 18 countries around the world, as well as a critical analysis of different SEA methodologies. The Handbook starts by introducing key SEA principles and the legal requirements of the new European SEA Directive (which became law in 2004). It then describes the implementation of SEA in 11 European Union countries, as well as the USA, Canada and New Zealand. This is contrasted with SEA requirements of four developing countries. The Handbook explores public participation issues and the wide-range of SEA methodologies used in terms of resources (soils, water and biodiversity) and sectors of activity (transport, agriculture, waste management and industry). The Handbook concludes with a discussion on best practice, capacity building and the future of SEA.
Implementing semantic web services : The SESA framework
Service-oriented computing has become one of the predominant factors in IT research and development efforts over the last few years. In spite of several standardization efforts that advanced from research labs into industrial-strength technologies and tools, there is still much human effort required in the process of finding and executing Web services.
Implementing Integrated Water Resources Management in Central Asia
This volume reproduces the proceedings of an Advanced Research Workshop held in Bishkek, which brought together all the most senior water resource managers in Central Asia, from Ministers to local experts and eminent academics.
Implementation and Application of Functional Languages ; 19th International Workshop, IFL 2007, Freiburg, Germany, September 27-29, 2007. Revised Selected Papers
This book constitutes the thoroughly refereed post-proceedings of the 19th International Workshop on Implementation and Applications of Functional Languages, IFL 2007, held in Freiburg, Germany in September 2007.The 15 revised full papers presented went through two rounds of reviewing and improvement and were selected from 33 submissions. The papers address all current theoretical and methodological issues on functional and function-based languages such as type checking, contract checking, compilation, parallelism, development and debugging, data structures, parsing as well as various performance related concepts.
Impact of the Environment on Human Migration in Eurasia ; Proceedings of the NATO Advanced Research Workshop, held in St. Petersburg, 15-18 November 2003
Beyond any doubt, the environment played an important role in the life of ancient nomadic populations, forming the basis of their economies and influencing various aspects of their mode of life.
Impact of Information Society Research in the Global South
This book addresses two aspects— Impact of research: How is the research on ICTs in the Global South playing a role in creating an information society? (e.g. policy formulation, media coverage, implementation in practice) and Research on impact: What is the evidence for the impact of ICTs on society? (i.e. the objectives of socio-economic development). This volume brings together a multiplicity of voices and approaches from social scientific research to produce an engaging volume for a variety of stakeholders including academics, researchers, practitioners, policy-makers and those in the business and civil sectors of society.
Impact of globalization and advanced technologies on online business models
Unravels and provides business managers and scholars with new development in managing the ever-increasing global and advance technology change influencing the running of online business
Immunology of fungal infections
Covers all aspects of the immunology of fungal infection. Beyond the basics, coverage includes recent developments in innate and adaptive immunological mechanisms involved in the host response to fungal infection.
Immunogenetics of Autoimmune Disease
Utoimmunity is the downstream outcome of a rather extensive and coordinated series of events that include loss of self-tolerance, peripheral lymphocyte Aactivation, disruption of the blood-systems barriers, cellular infiltration into the target organs and local inflammation. Cytokines, adhesion molecules, growth factors, antibodies, and other molecules induce and regulate critical cell functions that perpetuate inflammation, leading to tissue injury and clinical phenotype. The nature and intensity of this response as well as the physiological ability to restore homeostasis are to a large extent conditioned by the unique amino acid sequences that define allelic variants on each of the numerous participating mol ecules. Therefore, the coding genes in their germline configuration play a primary role in determining who is at risk for developing such disorders, how the disease progresses, and how someone responds to therapy. Although genetic components in these diseases are clearly present, the lack of obvious and homogeneous modes of transmission has slowed progress by prevent ing the full exploitation of classical genetic epidemiologic techniques. Furthermore, autoimmune diseases are characterized by modest disease risk heritability and m- tifaceted interactions with environmental influences. Yet, several recent discoveries have dramatically changed our ability to examine genetic variation as it relates to human disease. In addition to the development of large-scale laboratory methods and tools to efficiently recognize and catalog DNA diversity, over the past few years there has been real progress in the application of new analytical and data-manage ment approaches
