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Developmental Neurobiology
The text will serve as a readily tractable source for advanced undergraduate neuroscience majors and beginning graduate students who will benefit from a single source to begin their study of a more detailed understanding of neural development. Each chapter is peppered with a sound mixture of historical context and descriptions from both the vertebrate and invertebrate literature that best illustrate specific aspects of development. The liberal use of simple diagrams and tables, which readily illustrate complex issues, is a welcome addition for instructor and student alike.
Developmental Biology of Neoplastic Growth
In this book, tumour growth is perceived as a deviation from the normal development of the human organism. The molecular, cellular, and tissue determinants of different tumours are discussed showing that each is a different disease, often corresponding to a particular developmental stage. The natural history of several cancers illustrates how clinical incidence can be just the visible part of the iceberg, while the first changes at the tissue level sometimes occur several years before tumour growth becomes manifest.
Development of the Inner Ear
This book describes the embryonic development of the vertebrate inner ear in six chapters that span all aspects of inner ear development, In each chapter, a particular aspect of development of the inner ear is examined in terms of both classic embryologic experiments and more recent advances using molecular biological techniques.
Development and Plasticity in Sensory Thalamus and Cortex
This book intends to bring together systems and molecular approaches on various fundamental issues on thalamocortical development and plasticity. Functional cortical circuits cannot be appreciated without thalamocortical circuits and cortical development cannot be considered without thalamocortical pathway development. The 16 chapters address key questions with diversity of techniques; ranging from molecular genetics, in vitro and in vivo methods to classical anatomical, electrophysiological and imaging procedures. The conceptual approaches formulated in these chapters should be a rich source for future research in this area.
Designing Urban Food Policies : Concepts and Approaches
This book is for scientists and experts who work on urban food policies. It provides a conceptual framework for understanding the urban food system sustainability and how it can be tackled by local governments. Written by a collective of researchers, this book describes the existing conceptual frameworks for an analysis of urban food policies, at the crossroads of the concepts of food system and sustainable city.
Deoxynucleoside Analogs in Cancer Therapy
Emerging as an important new volume in the renowned Cancer Drug Discovery and Development™ series, Deoxynucleoside Analogs in Cancer Therapy expertly summarizes the current status of development and application of deoxynucleoside analogs. Authoritative up-to-date reviews are presented by scientists well known in their specific areas and all contributions include valuable sound advice on structure and topics. Organized into several sections, the first part covers general aspects of drug uptake and metabolism and explains how novel technology has enabled a rapid expansion of this field. The second part is concerned with a number of specific drugs including cytarabine, gemcitabine, troxacitabine, clofarabine and Ara-G. The final section covers pharmacokinetics, prodrugs, and specific applications such as radiosensitization, gene therapy, and the use of deoxynucleoside analogs as tracers
Dental pulp derived mesenchymal stromal cells
Presents an evaluation of stem cells from human dental pulp as a reliable stem cell source for cell-based therapy to stimulate tissue regeneration. In this thoroughly updated and expanded second edition, the author covers mesenchymal stem cell (MSC) biology, various sources of MSCs, and the therapeutic potential of MSCs. Tooth regeneration, dental pulp-derived MSC, and the therapeutic potential of dental pulp derived stem cells is also covered.
Dental Materials in Operative Dentistry
Outlines the clinical advantages and disadvantages as well as indications and contraindications of different materials. Topics include finishing and polishing restorations and the use of dental curing lights.
Dental gold alloys and gold nanoparticles for biomedical applications
Focuses on recent advances in dental gold alloys and gold nanoparticles (GNPs) for biomedical applications. Dental gold alloys combine several highly desirable mechanical properties, such as high strength, ductility, and elasticity, with an extremely robust chemical stability in the mouth.
Dendritic Neurotransmitter Release
This book presents recent developments in the neurophysiology of dendritic release of several chemical classes of transmitters in a number of different areas of the mammalian central nervous system. Once released from a neuron, these substances can act as neurotransmitters and/or neuromodulators, to autoregulate the original neuron, its synaptic inputs, and adjacent cells or, by volume transmission, to affect distant cells.
Dendritic Cells in Clinics
Great advances have taken place in basic research and the clinical usefulness of dendritic cells (DCs). It has now been clearly established, for instance, that these cells play a crucial role in immune responses against infectious diseases and cancers. Antigen-presenting DCs are widely distributed in the body and regulate both immunity and immune tolerance. Experimental studies have provided important insights into DCs and how they can be used for treating animal models of various diseases that occur in humans. The role of these cells in pathogenesis and the treatment of human diseases is elaborately set forth in this valuable book. Researchers in the field are optimistic that DCs, already in use for treating patients with cancers, soon can be used therapeutically for patients with chronic infections, autoimmune diseases, and allergic manifestations. This volume provides a working definition of DCs and also explains the phenotypes and functions of DCs so that these can be readily understood not only by clinicians but by immunologists, researchers, and students as well.
Deformable Models : Theory and Biomaterial Applications
Deformable Models: Theory and Biomaterial Applications is the second installation in the two-volume set Deformable Models which provides a wide cross-section of the methods and algorithms of variational and PDE methods in biomedical image analysis. The chapters are written by well-known researchers in this field, and the presentation style goes beyond an intricate abstraction of the theory into real application of the methods and description of the algorithms that were implemented. As such these chapters will serve the main goal of the editors of the volumes in bringing down to earth the latest in variational and PDE methods in modeling of soft tissues, covering the theory, algorithms, and applications of level sets and deformable models in medical image analysis.
Deformable Models : Biomedical and Clinical Applications
Deformable Models: Biomedical and Clinical Applications is the first entry in the two-volume set which provides a wide cross-section of the methods and algorithms of variational and Partial-Differential Equations (PDE) methods in biomedical image analysis. The chapters of Deformable Models: Biomedical and Clinical Applications are written by the well-known researchers in this field, and the presentation style goes beyond an intricate abstraction of the theory into real application of the methods and description of the algorithms that were implemented. As such these chapters will serve the main goal of the editors of these two volumes in bringing down to earth the latest in variational and PDE methods in modeling of soft tissues.
Defending Life : The Nature of Host-Parasite Relations
Defending Life discusses the relationship between hosts and parasites. A major contention of the book is that the immune system depends ontologically on the ecosystem in which it is embedded; it would not have the features it has if it was not related in one way or other to parasitic agents and to the host’s own cells and tissues. To sustain the argument, life is investigated at all layers – from molecules up through cells, organisms and ecosystems. Together with the inverse course, which goes from ecological contingencies down to gene-expression profiles, the approach facilitates an advanced understanding of immunocompetence as well as its converse, immunoincompetence. The emphasis on analytical abstractions, coherent patterns and generative mechanisms makes possible the distinction between genuine causality and coincidental associations, and thus increases the understanding of why we observe what we observe. The book contains detailed descriptions of the immune system and the microbial world as well as methodological and conceptual clarifications.
Defects of Secretion in Cystic Fibrosis
This book brings together physicians, physiologists, and other scientists involved in basic research, from molecular biology to drug design and introduces novel investigative and therapeutic aspects of secretion disorders relevant in cystic fibrosis and related diseases. This book will be of interest to Molecular biologists, physiologists, scientists working in pharmaceutical research and drug developement, physicians and researchers in Cystic fibrosis and related diseases.
Deep-water Coral Reefs : Unique Biodiversity Hot-Spots
Provides a useful overview of various aspects of deep-water coral reefs and carbonate mounds, providing insights into the physical processes, and inspire and stimulate further research into these fascinating natural systems. This book, presents and discusses only a selection of the world’s discovered deep-water coral reefs.
Deep Learning, Machine Learning and IoT in Biomedical and Health Informatics : Techniques and Applications
Examines and demonstrates state-of-the-art approaches for IoT and Machine Learning based biomedical and health related applications. This book aims to provide computational methods for accumulating, updating and changing knowledge in intelligent systems and particularly learning mechanisms that help us to induce knowledge from the data. It is helpful in cases where direct algorithmic solutions are unavailable, there is lack of formal models, or the knowledge about the application domain is inadequately defined. In the future IoT has the impending capability to change the way we work and live. These computing methods also play a significant role in design and optimization in diverse engineering disciplines. With the influence and the development of the IoT concept, the need for AI (artificial intelligence) techniques has become more significant than ever.
Decision Support for Forest Management
While earlier books concerning forest planning have tended to focus on linear programming, economic aspects, or specific multi-criteria decision aid tools, this book provides a much broader range of tools to meet a variety of planning situations. The methods themselves cover a range of decision situations – from cases involving single decision makers, through group decision making, to participatory planning. They include traditional decision support tools, from optimization to utility functions, as well as methods that are just gaining ground in forest planning – such as problem structuring methods and social choice theory. Including examples which illustrate the application of each technique to specific management planning problems, the book offers an invaluable resource for both researchers and advanced students specializing in management and planning issues relating to forestry.
Decision science for future earth : Theory and practice
Provides a theoretical framework and case studies on decision science for regional sustainability by integrating the natural and social sciences. The cases discussed include solution-oriented transdisciplinary studies on the environment, disasters, health, governance and human cooperation.
Deciphering Growth
Growth is a complex process that is essential to life. Not only does size play an important role in the process of cellular proliferation, but body size is also a critical factor in determining which organisms live longer. In mammals, the major factors involved in the regulation of body growth are known. The combined knowledge concerning the endocrine and paracrine aspects of growth have led to the introduction of treatment regimens, most effective in GH-deficient children.
