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Computational and Statistical Approaches to Genomics
Computational and Statistical Approaches to Genomics, 2nd Edition, aims to help researchers deal with current genomic challenges. During the three years after the publication of the first edition of this book, the computational and statistical research in genomics have become increasingly more important and indispensable for understanding cellular behavior under a variety of environmental conditions and for tackling challenging clinical problems. In the first edition, the organizational structure was: data à analysis à synthesis à application. In the second edition, the same structure remains, but the chapters that primarily focused on applications have been deleted.
Complexity in landscape ecology
Interactions matter. To understand the distributions of plants and animals in a landscape you need to understand how they interact with each other, and with their environment. The resulting networks of interactions make ecosystems highly complex. Recent research on complexity and artificial life provides many new insights about patterns and processes in landscapes and ecosystems. This book provides the first overview of that work for general readers. It covers such topics as connectivity, criticality, feedback, and networks, as well as their impact on the stability and predictability of ecosystem dynamics. With over 60 years of research experience of both ecology and complexity, the authors are uniquely qualified to provide a new perspective on traditional ecology.
Complex Systems Science in Biomedicine
Complex Systems Science in Biomedicine covers the emerging field of systems science involving the application of physics, mathematics, engineering and computational methods and techniques to the study of biomedicine including nonlinear dynamics at the molecular, cellular, multi-cellular tissue, and organismic level. With all chapters helmed by leading scientists in the field, Complex Systems Science in Biomedicine's goal is to offer its audience a timely compendium of the ongoing research directed to the understanding of biological processes as whole systems instead of as isolated component parts.
Complex Systems in Biomedicine
Features contributions from several Italian research groups that are working on the field of biomedicine. Each chapter in this book deals with a specific subfield, with the aim of providing an overview of the subject and an account of the research results.
Complex Intracellular Structures in Prokaryotes
The new series "Microbiology Monographs" begins with two volumes on intracellular components in prokaryotes. In this second volume, "Complex Intracellular Structures in Prokaryotes", the components, labeled complex intracellular structures, encompass a multitude of important cellular functions. Continuing and newly initiated research will provide a clearer understanding of the complex intracellular structures known at present and will bring to light surprising new ones as well.
Competence and Vulnerability in Biomedical Research
In this book, the author develops a novel justificatory framework for making judgments of decisional competence to consent to biomedical research with reference to five groups of cognitively vulnerable individuals - older children and adolescents, adults with intellectual disabilities, adults with depression, adults with schizophrenia and adults with dementia, including Alzheimer’s disease.
Community-Acquired Pneumonia
Community-acquired pneumonia (CAP) is a disease associated with high morbidity and mortality, with at least one third of cases requiring hospitalization, exceeding the numbers admitted for myocardial infarction and stroke. Despite a broad armamentarium of antimicrobials available, it remains an important cause of death in industrialized countries. CAP is caused by a variety of pathogens with their order of importance dependent on the location and population studied. Despite the importance of CAP, reliable data and a recommended evidence-based therapy are lacking, and basic research must be improved. The goal of this volume is to present state-of-the-art knowledge on epidemiology, clinical presentation, immunology, pathology, and diagnosis including the identification of "new pathogens". Therapeutic approaches, antibiotics resistance, disease management and vaccination strategies are also covered. The volume is of interest to researchers and clinicians in virology, epidemiology and biomedicine.
Common Chinese Materia Medica ; Vol.4
Describes 256 species of medicinal plants from 5 families, which are commonly used in Chinese medicine. The most important species are Agrimonia pilosa, Amygdalus persica, Armeniaca mume, Armeniaca vulgaris, Armeniaca sibirica, Chaenomeles sinensis, Eriobotrya japonica of Rosaceae; Chimonanthus praecox of Calycanthaceae；Albizia julibrissin, Archidendron clypearia, Entada phaseoloides, Bauhinia championii of Mimosoideae; Caesalpinia sappan, Cassia tora, Gleditsia sinensis of Caesalpiniaceae; Abrus cantoniensis, Astragalus membranaceus, Astragalus membranaceus, Dalbergia odorifera, Desmodium caudatum, Desmodium styracifolium, Erythrina variegata, Euchresta japonica, Flemingia prostrata, Glycyrrhiza uralensis, Glycyrrhiza inflata, Glycyrrhiza glabra, Lablab purpureus, Sophora japonica and Spatholobus suberectus of Butterflyaceae. In each specie, it introduces the scientific names, medicinal names, morphologies, habitats, distributions, acquisition and processing methods of these medicinal plants, the content of medicinal properties, therapeutic effects, usage and dosage of these medicinal plants, and attaches unedited color pictures and pictures of part herbal medicines of each species. This book series has 10 volumes in total, which covers over 2000 kinds of Chinese medicines that are commonly used. These volumes not only introduce the efficacy function and some prescriptions of the medicines, but also introduce the biological characteristics of them in detail with clear photos of the habitats, so that readers can identify them in the field. Apart from the growing environment, the books expound the distribution areas and other information to facilitate researches and other applications. The volumes are targeted at readers of general interests and it is also of high referential value for scientific researcher and teachers. It can be used as a guide to researchers, clinical doctors, and students in the department of pharmaceutics and traditional Chinese medicine.
Common Chinese materia medica ; Vol.2
Contains 231 species of 40 families of medicinal plants. The most important family of which are Magnoliaceae, such as Magnolia officinalis and Magnolia officinalis subsp. biloba; Schisandra chinensis of Schisandraceae; Cinnamomum aromaticum of Lauraceae, Coptis chinensis Franch., Coptis omeiensis and Coptis teeta of Berberidaceae; Isatis indigotica, Lepidium apetalum and Raphanus sativus of Cruciferae; Rheum palmatum, Rheum officinale and Rheum taguticum of Polygonaceae, etc. In each specie, it introduces the scientific names, herbal medicine names, characteristics, habitats, distributions, Acquisition and processing methods, medicinal traits, tastes, functions, use and dosages, and other information of medicinal plants, and attaches unedited color pictures and pictures of part herbal medicines for each species. This book series has totally 10 volumes, which covers 2000 kinds of Chinese medicines that are commonly seen or used. These volumes not only introduce the efficacy, function and some prescriptions of the medicines, but also introduce the biological characteristics of them in detail with clear photos of the habitats, so that readers can identify them in the field. Apart from the growing environment, the books expound the distribution areas and other information to facilitate researches and other applications. The volumes are targeted at readers of general interests and it is also of high referential value for scientific researcher and teachers. It can be used as a guide to researchers, clinical doctors, and students in the department of pharmaceutics and traditional Chinese medicine.
Clinical Neuroembryology : Development and Developmental Disorders of the Human Central Nervous System
Combines data from human embryology, animal research and developmental neuropathology. This book provides an overview of the development of the human Central Nervous System (CNS) in the context of its many developmental disorders due to genetic, environmental and hypoxic causes. It highlights numerous clinical cases and contains over 400 figures.
Clinical biochemistry and drug development : From fundamentals to output
Focuses on clinical biochemistry fundamentals, cell culture techniques, and drug discovery and development concepts. It deals with three different fields of clinical research: cell culture, clinical biochemistry, and drug discovery and development.
Classical Biological Control of Bemisia tabaci in the United States : A Review of Interagency Research and Implementation
This book reviews the interagency research and development effort on classical biological control in the USA from 1992-2002. The successful exploration, importation, screening, evaluation, rearing, and establishment of at least five exotic Bemisia. tabaci natural enemies in rapid response to the devastating infestations in the USA is a landmark in interagency cooperation and coordination of multiple disciplines. In this volume, the various authors present detailed reviews of natural enemy exploration, introduction, and evaluation efforts that will serve as a guide to support and encourage classical biological control inputs into other integrated pest management systems.
Class 2 Transferases I : EC 2.1.1
This new, second edition reflects considerable progress in enzymology: many enzymes are newly classified or reclassified. Each entry is correlated with references and one or more source organisms. New datafields are created: application and engineering (for the properties of enzymes where the sequence has been changed). The total amount of material contained in the Handbook has more than doubled so that the complete second edition consists of 39 volumes as well as a Synonym Index. In addition, starting in 2009, all newly classified enzymes are treated in Supplement Volumes. Springer Handbook of Enzymes is an ideal source of information for researchers in biochemistry, biotechnology, organic and analytical chemistry, and food sciences, as well as for medicinal applications
Class 1 Oxidoreductases XI : EC 1.14.11 - 1.14.14
This new, second edition reflects considerable progress in enzymology: many enzymes are newly classified or reclassified. Each entry is correlated with references and one or more source organisms. New datafields are created: application and engineering (for the properties of enzymes where the sequence has been changed). The total amount of material contained in the Handbook has more than doubled so that the complete second edition consists of 39 volumes as well as a Synonym Index. In addition, starting in 2009, all newly classified enzymes are treated in Supplement Volumes. Springer Handbook of Enzymes is an ideal source of information for researchers in biochemistry, biotechnology, organic and analytical chemistry, and food sciences, as well as for medicinal applications.
Class 1 Oxidoreductases X : EC 1.9 - 1.13
This new, second edition reflects considerable progress in enzymology: many enzymes are newly classified or reclassified. Each entry is correlated with references and one or more source organisms. New datafields are created: application and engineering (for the properties of enzymes where the sequence has been changed). The total amount of material contained in the Handbook has more than doubled so that the complete second edition consists of 39 volumes as well as a Synonym Index. In addition, starting in 2009, all newly classified enzymes are treated in Supplement Volumes. Springer Handbook of Enzymes is an ideal source of information for researchers in biochemistry, biotechnology, organic and analytical chemistry, and food sciences, as well as for medicinal applications.
Class 1 Oxidoreductases VIII : EC 1.5
Springer Handbook of Enzymes provides data on enzymes sufficiently well characterized. It offers concise and complete descriptions of some 5,000 enzymes and their application areas. Data sheets are arranged in their EC-Number sequence and the volumes themselves are arranged according to enzyme classes. This new, second edition reflects considerable progress in enzymology: many enzymes are newly classified or reclassified. Each entry is correlated with references and one or more source organisms. New datafields are created: application and engineering (for the properties of enzymes where the sequence has been changed). Springer Handbook of Enzymes is an ideal source of information for researchers in biochemistry, biotechnology, organic and analytical chemistry, and food sciences, as well as for medicinal applications.
Class 1 Oxidoreductases VII : EC 1.4
Springer Handbook of Enzymes provides data on enzymes sufficiently well characterized. It offers concise and complete descriptions of some 5,000 enzymes and their application areas. Data sheets are arranged in their EC-Number sequence and the volumes themselves are arranged according to enzyme classes. This new, second edition reflects considerable progress in enzymology: many enzymes are newly classified or reclassified. Each entry is correlated with references and one or more source organisms. New datafields are created: application and engineering (for the properties of enzymes where the sequence has been changed). Springer Handbook of Enzymes is an ideal source of information for researchers in biochemistry, biotechnology, organic and analytical chemistry, and food sciences, as well as for medicinal applications.
Class 1 Oxidoreductases IX : EC 1.6 - 1.8
Springer Handbook of Enzymes provides data on enzymes sufficiently well characterized. It offers concise and complete descriptions of some 5,000 enzymes and their application areas. Data sheets are arranged in their EC-Number sequence and the volumes themselves are arranged according to enzyme classes. This new, second edition reflects considerable progress in enzymology: many enzymes are newly classified or reclassified. Each entry is correlated with references and one or more source organisms. New datafields are created: application and engineering (for the properties of enzymes where the sequence has been changed). Springer Handbook of Enzymes is an ideal source of information for researchers in biochemistry, biotechnology, organic and analytical chemistry, and food sciences, as well as for medicinal applications.
Cigarette Smoke and Oxidative Stress
From a public health point of view, there is little doubt that one of the most important preventable causes of disease worldwide is tobacco smoking. From a scientifc point of view, we found it of interest to make a comprehensive ov- view of what we presently know about oxidative stress and tobacco smoke, because sm- ing is presently the best-known common condition associated with oxidative stress, and it may serve as a model for others. To this end, we have asked distinguished researchers from the public and the private sectors to evaluate the present scientifc status in their particular area. Authors were selected purely because of their scientifc merits.
Chronic Viral and Inflammatory Cardiomyopathy
This publication constitutes the outcome of an ESRF meeting held together with the German Research Foundation. Clinical researchers, immunologists, virologists and molecular biologists provide the latest findings in their fields, advancing our understanding of what causes chronic viral and inflammatory cardiomyopathy, why it affects a subset of individuals while sparing the majority, how we can develop better therapies, and whether the disease can be prevented. Special emphasis is placed on the role of viruses in the aetiology and pathogenesis of cardiomyopathy.
