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Bioanalytics : Analytical methods and concepts in biochemistry and molecular biology

Analytical methods are the essential enabling tools of the modern biosciences. This book presents a comprehensive introduction into these analytical methods, including their physical and chemical backgrounds, as well as a discussion of the strengths and weakness of each method. It covers all major techniques for the determination and experimental analysis of biological macromolecules, including proteins, carbohydrates, lipids and nucleic acids.

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Bioactive egg compounds

Hen eggs have exceptional potential as an inexhaustible source for a variety of products with unique properties. These products are valuable to human health and nutrition and can be used as raw materials for diverse purposes in the cosmetics and pharmaceutical industries. Bioactive Egg Compounds presents the latest results and concepts in the biotechnological use of egg compounds. Following an introduction to the different compounds of egg white, yolk and shell, the nutritive value of egg compounds is discussed. Procedures for processing egg compounds to improve their nutritive value are described, including the concept of so-called enriched eggs. Also described is the isolation and application of egg compounds with special properties, such as antibiotic action.

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Bee products : Chemical and biological properties

Presents an updated discussion on the chemical composition and biological properties of the main bee products, which until now have been presented separately in different editions This book scoops out studies about bee products most used in marketing and in traditional medicine such as honey, royal jelly, propolis, bee pollen and bee venom Discusses chemical composition and biological function of the different bee products on topics such as nutrition, aging and age-related diseases, cancer, neurodegenerative diseases and pathogen infections Bee products are rich in several essential nutrients and non essential nutrients, as sugars, minerals, proteins, free amino acids, vitamins, enzymes and polyphenols, that seem to be closely related to their biological functions. The effects of these products in nutrition, aging and age-related diseases, cancer, neurodegenerative diseases and pathogen infections are discussed.

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Basic methods for the biochemical lab

Covers : quantitative methods (proteins, nucleic acids, phospholipids and carbohydrates), electrophoresis (several polyacrylamide and agarose systems, 2D-PAGE, detection methods and affinity electrophoresis), chromatographic protocols (thin-layer chromatography, GPC, IEC, affinity chromatography, HPLC), immunochemical protocols (hapten-carrier and enzyme conjugation, immunization and antibody purification, immune affinity chromatography, ELISA), centrifugation (differential and density gradient centrifugation for cells and cellular fractions), radioactivity (labeling and counting), buffers (buffer properties and compositions).

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Anti-viral metabolites from medicinal plants

Covers general concepts of anti-viral metabolites, classifications, ethnopharmacology, chemistry, clinical and preclinical studies focusing on different medicinal plants against various types of viral infections. Various plants have been used in medicine since ancient times and are known for their strong therapeutic effects. The book will describe potential antiviral properties of medicinal plants against a diverse group of viruses, and provide an insight to the potential plants possess for broad-spectrum antiviral effects against emerging viral infections.The book aims to target a broad audience including virologists, molecular biologist, microbiologist and scientists working with natural products as well as researchers, students, healthcare experts involved in pharmaceutical and medical field.

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Antimalarial natural products

Begins with a short history of malaria and follows with a summary of its biology. It then traces the fascinating history of the discovery of quinine for malaria treatment, and then describes quinine’s biosynthesis, its mechanism of action, and its clinical use, concluding with a discussion of synthetic antimalarial agents based on quinine’s structure. It also covers the discovery of artemisinin and its development as the source of the most effective current antimalarial drug, including summaries of its synthesis and biosynthesis, its mechanism of action, and its clinical use and resistance. A short discussion of other clinically used antimalarial natural products leads to a detailed treatment of additional natural products with significant antiplasmodial activity, classified by compound type.

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Alzheimers disease : Cellular and molecular aspects of Amyloid beta

This book contains a survey of present-day research into the biomedical fundamentals of Alzheimer’s disease (AD). It contains 20 chapters dealing with widely ranging topics, all of which have a bearing upon the understanding and treatment of AD. Starting with a broad survey of the contribution that the various microscopical techniques (light microscopy, electron microscopy, atomic force microscopy)

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Alzheimers Disease : Advances in genetics, molecular and cellular biology

Alzheimer’s Disease: Advances in Genetics, Cellular and Molecular Biology provides exciting, comprehensive and up-to-date summaries of the most important recent advances in the genetic, molecular, biochemical, and cell biological studies of AD. The studies and advances described in this volume will help to accelerate the process of rational drug discovery and soon serve to extend and enhance the mental health and lifespan of our burgeoning elderly population.

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Advances in Molecular Breeding Toward Drought and Salt Tolerant Crops

Advances in Molecular Breeding toward Drought and Salt Tolerant Crops seeks to integrate the most recent findings about key biological determinants of plant stress tolerance with modern crop improvement strategies. This volume is unique because is provides exceptionally wide coverage of current knowledge and expertise being applied in drought and salt tolerance research, spanning the scientific hierarchy from physiology, biochemistry, development, and genetics, to the newest technologies being used to manipulate drought and salinity associated traits for germplasm improvement. This book will be an invaluable reference for educators and researchers in agronomy and horticulture, crop breeding, molecular genetics, and biotechnology.

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Advances in Alzheimer’s and Parkinson’s Disease : Insights, Progress, and Perspectives

Proceedings of the 7th International Conference on Alzheimer’s Disease and Parkinson’s Disease (ADPD), held March 9-13, 2005 in Sorrento, Italy.The subject matter of the ADPD conferences is unique in that it deals not only with issues related individually to Alzheimer’s disease and Parkinson’s disease, but also with the integration of these and other related diseases. The most up-to-date techniques and research findings are illustrated in this volume, covering topics such as immunology, neuroscience, pharmacology, genetics, molecular biology, biochemistry and the history, epidemiology, clinical phenomenology, diagnosis, imaging, treatment ,and future perspectives of Alzheimer’s and Parkinson’s Diseases.

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Advanced chemical biology : chemical dissection and reprogramming of biological systems

Organized around the central dogma of life, progressing from genes to proteins and higher-order cellular structures, including core application areas such as imaging, chemical genetics, activity-based protein profiling, and natural product discovery and biosynthesis. Advanced topics and applications in, e. g., microbiology, developmental biology, and neurobiology, are covered in separate sections.

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Adrenomedullin in Cardiovascular Disease

Adrenomedullin in Cardiovascular Disease is an up-to-date review of the most relevant aspects of adrenomedullin. It encompasses a broad range of fields including biochemistry, molecular biology, physiology, pharmacology, pathophysiology of cardiovascular disease and clinical applications of adrenomedullin to cardiovascular disease.

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Actin-Binding Proteins and Disease

This volume, written by experts in the field, is the first to deal with the relationship between human disease and the actin cytoskeleton. It provides overviews of actin and selected actin-binding proteins, and then focuses on diseases that involve these proteins. Specific chapters deal with actin, cofilin, profilin, gelsolin and thymosin ¾4. Other chapters discuss the roles of multiple actin-binding proteins in cancer and metastasis, leukocyte disorders, and heart failure, and there is a chapter that describes how intracellular pathogens use the host actin cytoskeleton. This seminal volume is intended for researchers, clinicians, physicians, and graduate students in the fields of biochemistry, cell biology, microbiology, immunology, and genetics.

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Abeta Peptide and Alzheimers Disease : Celebrating a Century of Research

Abeta Peptide and Alzheimer’s Disease summarizes current knowledge of beta-amyloid peptide (Aß) and its role as the major culprit in Alzheimer’s Disease (AD), shown by recent advances in genetics and brain biochemistry.the book covers fundamental biochemical studies on the Aß peptide, the genetic impact on Aß expression and processing, and various AD therapeutic strategies that target Aß. Although specifically focusing on Aß and AD, there is also some discussion on the similarity and differences of this peptide and AD with other amyloidogenic diseases.

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A Legacy for Living Systems : Gregory Bateson as Precursor to Biosemiotics

This book represents a major attempt to revise this deficiency. Scholars from ecology, biochemistry, evolutionary biology, cognitive science, anthropology and philosophy discuss how Bateson's thinking might lead to a fruitful reframing of central problems in modern science. Most important perhaps, Bateson's bioanthropology is shown to play a key role in developing the set of ideas explored in the new field of biosemiotics. The idea that organismic life is indeed basically semiotic or communicative lies at the heart of the biosemiotic approach to the study of life.The only book of its kind, this volume provides a key resource for the quickly-growing substratum of scholars in the biosciences, philosophy and medicine who are seeking an elegant new approach to exploring highly complex systems.

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Algorithms in Bioinformatics ; 8th International Workshop, WABI 2008, Karlsruhe, Germany, September 15-19, 2008. Proceedings

This book constitutes the refereed proceedings of the 8th International Workshop on Algorithms in Bioinformatics, WABI 2008, held in Karlsruhe, Germany, in September 2008 as part of the ALGO 2008 meeting.

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Anatomy : Regional, Surgical, and Applied

Presents a concise, accessible guide to regional and clinically applied anatomy, which clearly demonstrates to students the level of knowledge required for medical and healthcare-related curricula / Uses high-quality clinical and intraoperative images integrated into the text to emphasizes important topics through bullet points / Features logically arranged sections, each devoted to a body region or system, which includes a self-test quiz, with the single best answer and spotter-style questions

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Mathematical Modeling of Biological Systems ; Vol. I : Cellular Biophysics, Regulatory Networks, Development, Biomedicine, and Data Analysis

This two-volume, interdisciplinary work is a unified presentation of a broad range of state-of-the-art topics in the rapidly growing field of mathematical modeling in the biological sciences. Highlighted throughout both works are mathematical and computational approaches to examine central problems in the life sciences, ranging from the organizational principles of individual cells to the dynamics of large populations.

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Marine Biotechnology I

Oceans, which occupy up to two thirds of the surface of our planet, were not really approached from scientific point of view until the second half of the 19th century and even the 20th with regard to microbial and unicellular life. Today, the importance of marine biodiversity has been fully recognized. It is, indeed, one of the aspects which, over the two past decades, have made a major contribution to our knowledge and vision of the living planetThis volume of Advances in Biochemical Engineering/Biotechnology illustrates several topics in line with the following broad objectives: thinking ofmarine biotechnology as the controlled production and use of marine organisms and molecules for useful purposes, firstly by exploring aspects of marine biodiversity and exploitation of biomass, then considering the identification, production and processing of marine products.

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Low Molecular Mass Gelators : Design, Self-Assembly, Function

Chapter 1 presents the physical principles of the growth mechanism of fiber and fiber network with LMGs, as treated on the basis of the heterogeneous nucleation model. in Chaps. 2 and 3, respectively. These chapters are intended to outline useful synthetic guidelines for the generation of an ever-increasing variety of molecular architectures within these two families of gelators. Recent developments in the chemistry of nucleobase-containing LMGs are described in Chap. 4. Hydrogen-bonding within these molecular systems involves complementary base pair formation, a process relevant to DNA double-helix formation The self-assembly of chiral organo- or hydrogelators is the subject of Chap. 5. result from the orthogonal self-assembly of liquid crystals and LMGs are presented in Chap. 6. The volume concludes with Chap. 7, a review of the emerging field of dendritic gels.

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