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No More Muddling Through : Mastering Complex Projects in Engineering and Management

Systems Engineering (SE) is a systematic way of thinking and a methodology to guide demanding problem-solving processes in the fields of management and engineering. This book explains the most important principles and elements of Systems Engineering and three planning cases demonstrate the practical application.

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Nimesulide - Actions and Uses

Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) which acts as a cyclooxygenase- 2 inhibitor but also has other novel pharmacological features which account for its effect in the control of pain and inflammation. It has become a leading NSAID in over 50 countries worldwide. This book provides a comprehensive and fully up-to-date critical review of the published literature on nimesulide, including comparisons with anti-inflammatory, analgesic and antipyretic agents. The emphasis is on the action of nimesulide in relation to its therapeutic and side effects in comparison with other established NSAIDs, including the new class of Coxibs.

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Nicotinic Acetylcholine Receptor Signaling in Neuroprotection

Presents the roles and mechanisms of signal transduction triggered by nicotinic acetylcholine receptors (nAChRs) stimulation in neuroprotection against toxic effects of risk factors of neurodegenerative diseases. Accumulating evidence suggests that nAChRs in the CNS play important roles not only in excitatory neurotransmission but also in neuronal survival and related functions. Neuroprotection mediated by nAChRs in neurodegenerative diseases such as Alzheimer's disease is the major topic of this book. In response to rapidly evolving areas in clinical and laboratory neuropharmacology and neurochemistry, this volume provides in-depth coverage of neuroprotection in basic research and future developments in the clinical application of effective neuroprotective strategies in neurodegenerative diseases. This work appeals to both basic and clinical researchers in several fields, such as neuroscience, neurology, and pharmacology.

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Next Generation Supply Chains : A Roadmap for Research and Innovation

This book explores supply chains strategies to help companies face challenges such as societal emergency, digitalization, climate changes and scarcity of resources. The book identifies industrial scenarios for the next decade based on the analysis of trends at social, economic, environmental technological and political level, and examines how they may impact on supply chain processes and how to design next generation supply chains to answer these challenges.

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Newman and Carranza's Clinical Periodontology and Implantology

Provides detailed, up-to-date information on the etiology and pathogenesis of periodontal disease. Basic and advanced evidence-based information on the various treatment modalities employed in periodontics and implantology is presented in an easy-to-read format, with callout boxes throughout the text highlighting the clinical relevance of foundational basic science information. Full-color photos and radiographic images depict periodontal conditions and procedures, and the Atlas of Periodontal Pathology is one of the most comprehensive ever compiled in a periodontal textbook. Written by a team of leading experts led by Michael G. Newman, this text not only demonstrates how to perform periodontal procedures but explains the evidence supporting each treatment and provides knowledge on how to achieve the best possible outcomes of periodontal therapy and implant treatment. An eBook version is included with print purchase, providing access to all the text, figures, and references, plus the ability to search, customize content, make notes and highlights, and have content read aloud.

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New Trends in Macroeconomics

This volume does exactly what its title says: it acquaints with 'New Trends in Macroeconomics'. More specifically, it contains eleven chapters covering different aspects of modern macroeconomics: short-run fluctuations, long-run growth, monetary economics, international finance, macroeconometrics and complex dynamics. All chapters break new grounds in their area while at the same time remain very accessible. The book contains also an excellent mixture of new techniques, interesting applications and methodological arguments. A valuable reference for both practitioners and researchers, it will also be of great help to gradutate students seeking to bring themselves to the frontier of one of the most fascinating fields of economics

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New Trends in Cancer for the 21st Century

It is difficult to imagine anyone who has not heard of cancer. This disease can affect families, friends or any one of us at any time in our lives. Every year nearly 3 million Europeans are diagnosed with cancer, leading to around 800,000 deaths per year. These deaths occur not only in aging populations, but also in children and adults who are in the most active period of their lives. This represents a tremendous problem that cannot be ignored by politicians or citizens. Fortunately, there is a constantly growing awareness that although cancer is a problem to be dealt with by clinicians, it should also be the concern of everyone. This volume contains the lectures held at the International Symposium on Cancer "New Trends in Cancer for the 21st Century". Fundamental researchers, politicians and representatives from patient coalitions share here their knowledge and interests as well as their concerns and experiences. Not only do these papers provide state-of-the-art information on cancer, they are also an opportunity to look at the problem from different points of view. It can be encouraging to realise that we are not alone in this fight.

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New Results in Numerical and Experimental Fluid Mechanics V ; Contributions to the 14th STAB/DGLR Symposium Bremen, Germany 2004

This volume contains the contributions to the 14. Symposium of the STAB (German Aerospace Aerodynamics Association). The volume gives a broad overview over the ongoing work in this field in Germany, with the topics being high-aspect ratio wings, low aspect-ratio wings, bluff bodies, laminar flow control and transition, active flow control, hypersonic flows, aeroelasticity, aeroacoustics, mathematical fundamentals/ numerical simulation, physical fundamentals, and facilities.

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New pharmacological hypothesis for cancer therapy and treatment

Despite the considerable development of new cancer drugs the mortality remains high and the improvement in survival rate remains poor compared to the number of new concepts of cancer therapy in which we will review in our study and we will focus on two possible reasons for that delay in success such as the limitation of diagnostic tools to perform early detection for the tumor in a stage where it can be well treated or even cured as it is often a silent disease in the start phase of it...

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New Perspectives on Aloe

The contents include a brief introduction of aloe, isolation, purification, and structural analysis of components, and various physiological effects of those components for possible use as health foods or drugs. Various functions identified were wound healing, angiogenesis, anti-allergy, skin whitening, stimulation of cell proliferation such as liver or kidney, protection against nephrotoxicity, and immune modulation. Moreover, we suggest standardization and quality control procedures for manufacturing raw aloe, and how to develop related products for successful application of aloe. This is important in Korea because last year the Korean government listed aloe as a health food for which the government establishes regulatory laws. Therefore, many scientists in Korea who are interested in studying health foods would be interested in this kind of text. Other major fields related to this kind of research will be medicine, biology, pharmaceutics, natural products and analytics.

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New perspectives in critical data studies: the ambivalences of data power

Examines the ambivalences of data power. Firstly, the ambivalences between global infrastructures and local invisibilities challenge the grand narrative of the ephemeral nature of a global data infrastructure. They make visible local working and living conditions, and the resources and arrangements required to operate and run them. Secondly, the book examines ambivalences between the state and data justice. It considers data justice in relation to state surveillance and data capitalism, and reflects on the ambivalences between an “entrepreneurial state” and a “welfare state”. Thirdly, the authors discuss ambivalences of everyday practices and collective action, in which civil society groups, communities, and movements try to position the interests of people against the “big players” in the tech industry.

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New Horizons of Parallel and Distributed Computing

Parallel and distributed computing is one of the foremost technologies for shaping future research and development activities in academia and industry. Hyperthreading in Intel processors, hypertransport links in next generation AMD processors, multicore silicon in today’s high-end microprocessors, emerging cluster and grid computing, has moved parallel/distributed computing into the mainstream of computing. New Horizons of Parallel and Distributed Computing is a collection of self-contained chapters written by pioneers and researchers to provide solutions for newly emerging problems in this field. This volume will not only provide novel ideas, work in progress and state-of-the-art techniques in the field, but also stimulate future research activities in the area of parallel and distributed computing with applications. New Horizons of Parallel and Distributed Computing is intended for researchers and graduate students in computer science and electrical engineering, as well as researchers and developers in industry. This book can be used as a textbook and a reference for use by students, researchers, and developers.

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New Directions and Applications in Control Theory

This volume contains a collection of papers in control theory and applications presented at a conference in honor of Clyde Martin on the occasion of his 60th birthday, held in Lubbock, Texas, November 14-15, 2003.

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New Dimensions of Business Reporting and XBRL

The authors of this book analyse the social and technical nature and role of XBRL in information supply chains and capital markets as well as the XBRL standard and taxonomies. They provide a critical view of XBRL from a research perspective, present different projects in the XBRL area and indicate future directions for XBRL research. Current research questions are taken up and discussed from different perspectives. From a technical point of view, the research spectrum encompasses the internal perspective up to the final user layer. Apart from these technical issues, there are also key socio-technical aspects which are vital to the understanding of XBRL use.

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New Developments in Parsing Technology

Parsing can be defined as the decomposition of complex structures into their constituent parts, and parsing technology as the methods, the tools, and the software to parse automatically. Parsing is a central area of research in the automatic processing of human language. Parsers are being used in many application areas, for example question answering, extraction of information from text, speech recognition and understanding, and machine translation. New developments in parsing technology are thus widely applicable. This book contains contributions from many of today's leading researchers in the area of natural language parsing technology. The contributors describe their most recent work and a diverse range of techniques and results. This collection provides an excellent picture of the current state of affairs in this area. This volume is the third in a series of such collections, and its breadth of coverage should make it suitable both as an overview of the current state of the field for graduate students, and as a reference for established researchers.

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New Developments in Computational Fluid Dynamics ; Proceedings of the Sixth International Nobeyama Workshop on the New Century of Computational Fluid Dynamics, Nobeyama, Japan, April 21 to 24, 2003

This volume contains 20 papers in Nobeyama Workshop focuses on predicting the next one hundred years of development of Fluid Dynamics, accounting for the current status and future trends of high performance computation and communication.

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New Developments in Classification and Data Analysis ; Proceedings of the Meeting of the Classification and Data Analysis Group (CLADAG) of the Italian Statistical Society, University of Bologna, September 22-24, 2003

This volume contains revised versions of selected papers presented during the biannual meeting of the Classification and Data Analysis Group of SocietA Italiana di Statistica, which was held in Bologna, September 22-24, 2003. The scientific program of the conference included 80 contributed papers. the conference provided a large number of scientists and experts from home and abroad with an attractive forum for discussions and mutual exchange of knowledge. The talks in the different sessions focused on methodological developments in supervised and unsupervised classification and in data analysis, also p- viding relevant contributions in the context of applications. This suggested the presentation of the 43 selected papers in three parts as follows: CLASSIFICATION AND CLUSTERING Non parametric classification Clustering and dissimilarities MULTIVARIATE STATISTICS AND DATA ANALYSIS APPLIED MULTIVARIATE STATISTICS Environmental data Microarray data Behavioural and text data Financial data

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New Challenges in Superconductivity : Experimental Advances and Emerging Theories ; Proceedings of the NATO Advanced Research Workshop, held in Miami, Florida, 11-14 January 2004

This volume contains the proceedings of the 2004 University of Miami Workshop on Unconventional Superconductivity. The workshop was the fourth in a series of successful meetings on High-T Superconductivity and C related topics, which took place at the James L. Knight Physics Building on the University of Miami campus in Coral Gables, Florida, in January 1991, 1995, 1999, and 2004. The workshop consisted of two consecutive events: 1. NATO Advanced Research Workshop (ARW) on New Challenges in Superconductivity: Experimental Advances and Emerging Theories, held on January 11-14, 2004; 2. Symposium on Emerging Mechanisms for High Temperature Superconductivity (SEMHTS), held on January 15-16, 2004.

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New Carbon Based Materials for Electrochemical Energy Storage Systems : Batteries, Supercapacitors and Fuel Cells

This NATO-ARW volume contains a diverse collection of papers addressing the role of carbon in some key electrochemical systems, both conventional and emerging. These papers discuss the latest issues associated with development, synthesis, characterization and use of new advanced carbonaceous materials for electrochemical energy storage. Such systems include: metal-air primary and rechargeable batteries, fuel cells, supercapacitors, cathodes and anodes of lithium-ion and lithium polymer rechargeable batteries, as well as nanocarbon materials of the future.

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New Algorithms for Macromolecular Simulation

Molecular simulation is a widely used tool in biology, chemistry, physics and engineering. This book contains a collection of articles by leading researchers who are developing new methods for molecular modelling and simulation. Topics addressed here include: multiscale formulations for biomolecular modelling, such as quantum-classical methods and advanced solvation techniques; protein folding methods and schemes for sampling complex landscapes; membrane simulations; free energy calculation; and techniques for improving ergodicity. The book is meant to be useful for practitioners in the simulation community and for those new to molecular simulation who require a broad introduction to the state of the art.

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