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Drug delivery trends ; Vol. 3 : Expectations and realities of multifunctional drug delivery systems
Examines a drift in the pharmaceutical field across the wide range of dosage forms, drug delivery systems (micro and nanoparticulate), at the regulatory front and on new types of therapies in the market. This book covers the challenges on drug delivery systems in terms of preclinical and current ways of determining quality and the options to solve the challenges associated with this. Most small-medium scale industries and academics struggle with initial regulatory challenges so a detailed discussion on regulatory trend covers the necessary basic understanding of regulatory procedures and provides the required guidance.
Domain-driven design with Java, a practitioner's guide : create simple, elegant, and valuable software solutions for complex business problems
Helps you as a developer and architect to put your knowledge to work in order to create elegant software designs that are enjoyable to work with and easy to reason about. You'll begin with an introduction to the concepts of domain-driven design and discover various ways to apply them in real-world scenarios. You'll also appreciate how DDD is extremely relevant when creating cloud native solutions that employ modern techniques such as event-driven microservices and fine-grained architectures. As you advance through the chapters, you'll get acquainted with core DDD's strategic design concepts such as the ubiquitous language, context maps, bounded contexts, and tactical design elements like aggregates and domain models and events. You'll understand how to apply modern, lightweight modeling techniques such as business value canvas, Wardley mapping, domain storytelling, and event storming, while also learning how to test-drive the system to create solutions that exhibit high degrees of internal quality.
DNA Methylation and Cancer Therapy
DNA methylation pat terns emerged as the only component of the chemical structure of DNA that exhibited tissue and cell specificity. This data seemingly provided an attrac tively simple explanation for the longstanding dilemma of how could one identical genome manifest itself in so many different forms in multicellular organisms? The DNA methylation pattern has thus become the only known factor to confer upon DNA a unique cellular identity.
Distributed Embedded Control Systems : Improving Dependability with Coherent Design
Distributed Embedded Control Systems handles the domains encountered when designing a distributed embedded computer control system as an integrated whole. First to be discussed are some basic issues about real-time systems and their properties, specifically safety. Then, system and hardware architectures are dealt.
Distributed computing and internet technology ; 17th International Conference, ICDCIT 2021, Bhubaneswar, India, January 7–10, 2021, Proceedings
This book constitutes the proceedings of the 17th International Conference on Distributed Computing and Internet Technology, ICDCIT 2020, held in Bhubaneswar, India, in January 2021. The 13 full papers presented together with 4 short papers were carefully reviewed and selected from 99 submissions. The papers were organized in topical sections named: invited talks, cloud computing and networks, distributed algorithms, concurrency and parallelism, graph algorithms and security, social networks and machine learning, and short papers.
Dissecting the Molecular Anatomy of Tissue
The book provides an updated overview of molecular analysis of human tissues, and the impact this analysis has on diagnosis and prognosis of human diseases. Special emphasis is placed on human cancer and the future directions of the field. Methods of handling clinical tissue samples, including the impact of handling on subsequent molecular analysis, are also discussed. In addition, detailed protocols for molecular analysis of DNA, RNA and protein, with special emphasis on molecular analysis of highly complex human tissue samples containing mixtures of cell populations, are provided.
Dislocation and Degradation of Proteins from the Endoplasmic Reticulum
The present volume of Current Topics in Microbiology and Immunology c- tains seven chapters that illuminate various aspects of a protein’s genesis and terminal fate in the endoplasmic reticulum (ER). Increased knowledge of the biosynthetic pathways of glycoproteins allowed the identi?cation of the ER as an important site where such quality control decisions were made.
Discoveries in Photosynthesis
Conceived of as a way of summarizing the history of research advances in photosynthesis as of millennium 2000, the book evolved into a majestic and encyclopedic saga involving all of the basic sciences. This book is meant not only for the researchers and graduate students, but also for advanced undergraduates in Plant Biology, Microbiology, Cell Biology, Biochemistry, Biophysics and History of Science.
Discontinuous Finite Elements in Fluid Dynamics and Heat Transfer
Discontinuous Finite Elements in Fluid Dynamics and Heat Transfer offers its readers a systematic and practical introduction to the discontinuous finite element method. It moves from a brief review of the fundamental laws and equations governing thermal and fluid systems, through a discussion of different approaches to the formulation of discontinuous finite element solutions for boundary and initial value problems, to their applicaton in a variety of thermal-system and fluid-related problems, including: heat conduction problems / convection-dominant problems / computational compressible flows / external radiation problems / internal radiation and radiative transfer / free- and moving-boundary problems / micro- and nanoscale heat transfer and fluid flow / thermal fluid flow under the influence of applied magnetic fields.
Directory of microbicides for the protection of materials : A handbook
This edition is divided into two parts. In Part One 23 contributions of worldwide selected experts present extensively diversified information about: -Microbicides with regard to the relationship between chemical structure and mode of action and activity, -Research and development in consideration of registration procedures,Legislative aspects,The use of microbicides in the major application areas (18) which are described in detail.The Microbicide Data is organized into 21 substance classes (e.g. alcohols, aldehydes, acids, amides, etc.) and collected in Part Two.
Digital video and audio broadcasting technology : A practical engineering guide
"Digital Video and Audio Broadcasting Technology – A Practical Engineering Guide" deals with all the most important digital television, sound radio and multimedia standards such as MPEG, DVB, DVD, DAB, ATSC, T-DMB, DMB-T, DRM and ISDB-T. The book provides an in-depth look at these subjects in terms of practical experience.
Digital transformation in semiconductor manufacturing ; Proceedings of the 1st and 2nd European advances in digital transformation Conference, EADTC 2018, Zittau, Germany and EADTC 2019, Milan, Italy
This book reports on cutting-edge electrical engineering and microelectronics solutions to foster and support digitalization in the semiconductor industry.
Digital Signal Processing with Field Programmable Gate Arrays
Field-Programmable Gate Arrays (FPGAs) are revolutionizing digital signal processing as novel FPGA families are replacing ASICs and PDSPs for front-end digital signal processing algorithms. So the efficient implementation of these algorithms is critical and is the main goal of this book. It starts with an overview of today's FPGA technology, devices, and tools for designing state-of-the-art DSP systems. A case study in the first chapter is the basis for more than 40 design examples throughout. The following chapters deal with computer arithmetic concepts, theory and the implementation of FIR and IIR filters, multirate digital signal processing systems, DFT and FFT algorithms, advanced algorithms with high future potential, and adaptive filters. Each chapter contains exercises. The VERILOG source code and a glossary are given in the appendices. This edition has a new chapter on microprocessors, new sections on special functions using MAC calls, intellectual property core design and arbitrary sampling rate converters, and over 100 new exercises.
Digital Holography and Three-Dimensional Display : Principles and Applications
Digital (or electronic) holography and its application to 3-D display is one of the formidable problems of evolving areas of high technology that has been receiving great attention in recent years. The realization of life-size interactive 3-D displays has been a seemingly unobtainable goal. Technology is not quite at that level yet, but advances in 3-D display now allow us to take important steps toward the achievement of this objective. The reader is presented with the state-of-the-art developments in both digital holography and 3-D display techniques. The book contains a large amount of research material as well as reviews, new ideas and insights that will be useful for graduate students, scientists, and engineers working in the field.
Digital Holography : Digital Hologram Recording, Numerical Reconstruction, and Related Techniques
This book presents a self-contained treatment of the principles and major applications of digital hologram recording and numerical reconstruction (Digital Holography). The first part deals with optical foundations and the theory of holography. The next section describes how to record holograms directly with an electronic sensor (CCD) and describes the various reconstruction techniques. A special chapter is designated to digital holographic interferometry with applications in deformation and shape measurement and refractive index determination. Applications in imaging and microscopy are also described. The next part discusses special techniques such as digital light-in-flight holography, holographic endoscopy, information encrypting and comparative holography. In the last chapter related techniques of speckle metrology are treated briefly.
Diffusion in Condensed Matter : Methods, Materials, Models
Diffusion as the process of particle transport due to stochastic movement is a phenomenon of crucial relevance for a large variety of processes and materials. This comprehensive, handbook-style survey of diffusion in condensed matter gives detailed insight into diffusion as the process of particle transport due to stochastic movement. Leading experts in the field describe in 23 chapters the different aspects of diffusion, covering microscopic and macroscopic experimental techniques and exemplary results for various classes of solids, liquids and interfaces as well as several theoretical concepts and models. Students and scientists in physics, chemistry, materials science, and biology will benefit from this detailed compilation.
Dictyostelium discoideum : Methods and protocols
Discusses the latest advancements and techniques used to study Dictyostelium discoideum. The chapters in this book cover topics such as cytokinesis, membrane function and damage, and nutrient/bacterial processing; autophagy activation and function; protein localization, interaction, and activation; cell migration and contact guidance for quantification of cytoskeletal dynamics; and global mutational screening, transcriptome analyses, and proteomics that apply to all stages of the Dictyostelium life cycle and that may generalize to human disease models. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Diagnosis of pathogenic microorganisms : Causing infectious diseases
Infectious diseases are caused by the pathogenic microbial organisms. These microbes can multiply and can cause an infection, once they enter the body. Infectious diseases are transmissible, and may cause mild to life-threatening illnesses. It can be airborne, waterborne, foodborne, and soilborne. It can be spread through direct contact (human to human, animal to human). It has also been one of the leading causes of human deaths. Therefore, there is a need to have rapid diagnostic methods to prevent and control these diseases. This book titled “Diagnosis of Pathogenic Microorganisms Causing Infectious Diseases” will help the scientific community to understand the transmission dynamics of some infectious diseases of public health importance.
Developing secure auto-scaling military postponement e-service in Syria
This study is about developing a secure, autoscaling military postponement e-service in Syria, that allows Syrian citizens to conveniently access services provided by the Syrian Recruitment Department conveniently through their smartphones. Currently, many Syrian citizens need to use the services offered by the Recruitment Department, resulting in overcrowding in a single location for similar purposes. This situation places a significant burden on both citizens and the government. The mobile application will facilitate various services such as enlistment and postponing military service by employing a well-designed software architecture that ensures scalability and efficient distribution of these services.
Designing with the wind : Climate-derived architecture
This book explores wind-adaptive architectural design blending the parametric design with digital simulations and suggests a novel approach for specific, even extreme conditions, as the first step in creating architecture that can act in response to the nature around. The chapters propose an urban and architectural design that emerges from the specific wind microclimate of the design site and responds to the changes in the ambient wind conditions. The book looks closely at A) the interdisciplinary wind-driven design method for architects, engineers, and urbanists employing open-source software for CFD analysis and B) the tensegrity-membrane adaptive building façades.
