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Malignant Mesothelioma : Pathogenesis, Diagnosis, and Translational Therapies
(Review from JAMA) Malignant mesothelioma is an uncommon neoplasm usually associated with exposure to asbestos. Because of its low incidence, thorough reviews of the topic are hard to find. Harvey Pass and colleagues have edited an up-to-date, comprehensive book that includes a wide range of information, from a historical perspective to descriptions of the latest treatment. The authors . . . have written chapters on the carcinogenesis, molecular genetics, and clinical aspects of mesothelioma. Malignant Mesothelioma is suitable for a broad audience. Laboratory researchers will use it as a resource for information about the pathogenesis, animal models, molecular genetics, and cell lines of mesothelioma. . . . Clinicians will benefit from this complete guide to the presentation, prognosis, imaging, and treatment of the disease. I highly recommend this book to all who are interested in mesothelioma.
Male Sexual Function : A Guide to Clinical Management
Male Sexual Function: A Guide to Clinical Management, Second Edition, completely updates and reviews newer developments, including linking erectile dysfunction (ED) with lower urinary tract systems, advances in erectile physiology, and the appreciation of ED as a form of endothelial dysfunction and a harbinger of other potentially lethal forms of vascular disease. Treatments of ED as well as the background, causes, associated conditions, and diagnostic tools are also provided. This new updated edition also presents the facts of sexual function and dysfunction so that the practitioner can properly treat basic problems with easily prescribed therapies. Also included is a new chapter on cardiovascular disease as well as chapters on pelvic surgeries, intracavernous injections with vasoactive agents, and vacuum erection devices.
Malaria : Genetic and Evolutionary Aspects
This book was originally conceived at a conference at the University of Turin in Italy. The conference was organized to examine the so-called “Malaria Hypothesis”, that is to say, the higher fitness of t- lassemia heterozygotes in a malarial environment, and to pay tribute to the proponent of that hypothesis, J.B.S. Haldane. Contributors to this book examine certain genetic and evolutionary aspects of malaria which is a major killer of human populations, especially in Africa and Asia. There were attempts to discredit Haldane’s contribution from two directions: (a) it has been suggested that the “Malaria Hypothesis” was known long before Haldane and that there was nothing original about his idea (Lederberg 1999), and that (b) the hypothesis of heterozygote su- riority was first suggested by the Italian biologist Giuseppe Montalenti who communicated his idea to Haldane (Allison 2004).
Macrophytes in Aquatic Ecosystems : from Biology to Management ; Proceedings of the 11th International Symposium on Aquatic Weeds, European Weed Research Society
Macrophytes and macrophytes ecology have gained an added importance with the introduction of, and legal requirement to implement, the European Water Framework Directive. This reflects the valuable role that aquatic plant communities play in assessing the ecological status of water bodies. Significant changes in the status and general abundance of these communities has been recorded in the last three decades, consequent on such factors as global warming and, increasingly, on the spread of aggressive alien species. These changes have been most felt in those waters that are exploited for amenity and recreational pursuits. The increased biomass of aquatic vegetation in water bodies has adversely impacted on leisure use of these systems but has also impacted on their use for agricultural, flood relief, municipal and domestic purposes. The loss to national economies resulting from this excessive plant biomass has been appreciable and has put pressure on water managers to develop weed control procedures that are efficient, environmentally sensitive and cost-effective.
Lung Pathology
Learning the diagnostic elements of lung pathology requires not only great familiarity with a wide diversity of cases, but also a sharp eye for analyzing pictorial images. In Lung Pathology: A Consultative Atlas, leading experts offer a novel and substantive approach to the teaching of pulmonary pathology. Drawing on 263 challenging, yet exemplary, referral cases taken from files collected over 20 years by internationally renowned lung pathologist, Dr. Eugene Mark, the authors introduce his state-of-the-art approach to the interpretation of pulmonary pathology. This text includes the primary and/or differential diagnosis and the pertinent histological features of each case, as well as clinical history, when available. Key words or phrases in the text are highlighted and digitally hyperlinked to associated images or regions of interest within those images to assist the readers in their correlation. Novel and user friendly, Lung Pathology: A Consultative Atlas describes a cutting-edge diagnostic approach to pulmonary pathology, describing its principles and demonstrating its application in text and full-color illustrations drawn from 263 difficult cases of human lung pathologies.
Lunar Orbiter Photographic Atlas of the Near Side of the Moon
Organized to make it easy for astronomers to use, enabling ground-based images and views to be compared with the Orbiter photographs. The photographs are striking for their consistent Sun angles (for uniform appearance). All features are identified with their current IAU-approved names, and each photograph is located in terms of latitude and longitude. To help practical astronomers, all the photographs are systematically related to an Earth-based view.
Low-cost methods for molecular characterization of mutant plants : Tissue desiccation, DNA extraction and mutation discovery : Protocols
Offers low-cost and rapid molecular assays for the characterization of mutant plant germplasm. Detailed protocols are provided for the desiccation of plant tissues; the extraction of high-quality DNA for downstream applications; the extraction of single-strand-specific nucleases for single nucleotide polymorphism; and small insertion/deletion discovery using standard agarose gel electrophoresis. The methods described can be applied in any laboratory equipped for basic molecular biology and do away with the need for expensive freezers and toxic organic compounds.
Lotus japonicus Handbook
Represents the first effort to compile basic descriptions and methods for research in Lotus, including symbiotic processes, cell and molecular biology protocols, functional genomics, mutants, gene tagging and genetic analysis, transformation and reverse genetic analysis, primary and secondary metabolism, and an exhaustive update of the scientific literature available on this plant.
Logical Data Modeling : What it is and How to do it
LOGICAL DATA MODELING: What It Is and How To Do IT is directed toward three groups of people: (1) Business subject matter experts, (2) information technology professionals, (3) advanced students in Computer Science, Management Information Systems, and e-Business. Its purpose is to outline the basics of logical data modeling—specifically, data modeling for relational database management systems—in simple, practical terms and in a business context. The focus on relational data modeling is consciously made because it is superior in modeling real business activities.
Locational Tournaments in the Context of the EU Competitive Environment : A New Institutional Economics Approach to Foreign Direct Investment Policy Competition between Governments in Europe
The last decade has witnessed a dramatic change in attitude towards foreign direct investment (FDI) and a significant increase in competition between governments to attract FDI as a result. These "locational tournaments" are perpetuated not simply by classical factor endowments, but also by government interventions that impact both market imperfections and FDI flows.
Living Rivers : Trends and Challenges in Science and Management
All over the world, sustainable river basin management is a leading principle of policy plans and legal instruments for water management (e.g. the European Water Framework Directive). The evidence, however, to underpin the full scope of sustainability is rather scanty. In this book an integrative perspective on trends and challenges in river science and management is demonstrated. The three pillars underneath sustainable water management, ecology, economy and sociology, are elaborated by experts in their fields. A number of papers integrate the current knowledge on the structure, functioning and management of ‘living rivers’. The book includes data and experiences concerning the rivers Allier, Meuse, Rhine, Sava and Tagliamento in Europe and the river Illinois in the USA. Sustainable river basin management asks for un-orthodox rehabilitation programmes and ecosystem based and transboundary management approaches.
Lipids in Health and Disease
Lipids are functionally versatile molecules. They have evolved from relatively simple hydrocarbons that serve as depot storages of metabolites and barriers to the permeation of solutes into complex compounds that perform a variety of signalling functions in higher organisms. This volume is devoted to the polar lipids and their constituents. We have omitted the neutral lipids like fats and oils because their function is generally to act as deposits of metabolizable substrates. The sterols are also outside the scope of the present volume and the reader is referred to volume 28 of this series which is the subject of cholesterol. The polar lipids are comprised of fatty acids attached to either glycerol or sphingosine. The fatty acids themselves constitute an important reservoir of substrates for conversion into families of signalling and modulating molecules including the eicosanoids amongst which are the prostaglandins, thromboxanes and leucotrienes. The way fatty acid metabolism is regulated in the liver and how fatty acids are desaturated are subjects considered in the first part of this volume. This section also deals with the modulation of protein function and inflammation by unsaturated fatty acids and their derivatives. New insights into the role of fatty acid synthesis and eicosenoid function in tumour progression and metastasis are presented.
Linking Restoration and Ecological Succession
Recognizes the critical roles of disturbance ecology, landscape ecology, ecological assembly, invasion biology, ecosystem health, and historical ecology in habitat restoration and argues that restoration within a successional context will best utilize the lessons from each of these disciplines.
Linking and Aligning Scores and Scales
In this book, experts in statistics and psychometrics describe classes of linkages, the history of score linkings, data collection designs, and methods used to achieve sound score linkages. They describe and critically discuss applications to a variety of domains including equating of achievement exams, linkages between computer-delivered exams and paper-and-pencil exams, concordances between the current version of the SAT® and its predecessor, concordances between the ACT® and the SAT®, vertical linkages of exams that span grade levels, and linkages of scales from high-stakes state assessments to the scales of the National Assessment of Educational Progress (NAEP).
Linear Systems
Linear systems theory plays a broad and fundamental role in electrical, mechanical, chemical and aerospace engineering, communications, and signal processing. A thorough introduction to systems theory with emphasis on control is presented in this self-contained textbook. The book examines the fundamental properties that govern the behavior of systems by developing their mathematical descriptions. Linear time-invariant, time-varying, continuous-time, and discrete-time systems are covered. Rigorous development of classic and contemporary topics in linear systems, as well as extensive coverage of stability and polynomial matrix/fractional representation, provide the necessary foundation for further study of systems and control.
Linear Selection Indices in Modern Plant Breeding
This open access book focuses on the linear selection index (LSI) theory and its statistical properties. It addresses the single-stage LSI theory by assuming that economic weights are fixed and known - or fixed, but unknown - to predict the net genetic merit in the phenotypic, marker and genomic context. Further, it shows how to combine the LSI theory with the independent culling method to develop the multistage selection index theory. The final two chapters present simulation results and SAS and R codes, respectively, to estimate the parameters and make selections using some of the LSIs described. It is essential reading for plant quantitative geneticists, but is also a valuable resource for animal breeders.
Linear Optimization Problems with Inexact Data
Linear programming attracted the interest of mathematicians during and after World War II when the first computers were constructed and methods for solving large linear programming problems were sought in connection with specific practical problems—for example, providing logistical support for the U.S. Armed Forces or modeling national economies. Early attempts to apply linear programming methods to solve practical problems failed to satisfy expectations. There were various reasons for the failure. One of them, which is the central topic of this book, was the inexactness of the data used to create the models. This phenomenon, inherent in most pratical problems, has been dealt with in several ways. At first, linear programming models used "average” values of inherently vague coefficients, but the optimal solutions of these models were not always optimal for the original problem itself. Later researchers developed the stochastic linear programming approach, but this too has its limitations. Recently, interest has been given to linear programming problems with data given as intervals, convex sets and/or fuzzy sets. The individual results of these studies have been promising, but the literature has not presented a unified theory. Linear Optimization Problems with Inexact Data attempts to present a comprehensive treatment of linear optimization with inexact data, summarizing existing results and presenting new ones within a unifying framework.
Linear Models for Optimal Test Design
Begins with a reflection on the history of test design--the core activity of all educational and psychological testing. It then presents a standard language for modeling test design problems as instances of multi-objective constrained optimization. The main portion of the book discusses test design models for a large variety of problems from the daily practice of testing, and illustrates their use with the help of numerous empirical examples. The presentation includes models for the assembly of tests to an absolute or relative target for their information functions, classical test assembly, test equating problems, item matching, test splitting, simultaneous assembly of multiple tests, tests with item sets, multidimensional tests, and adaptive test assembly. Two separate chapters are devoted to the questions of how to design item banks for optimal support of programs with fixed and adaptive tests. Linear Models for Optimal Test Design, which does not require any specific mathematical background, has been written to be a helpful resource on the desk of any test specialist.
Linear Differential Equations and Group Theory from Riemann to Poincaré
A study of how a particular vision of the unity of mathematics, often called geometric function theory, was created in the 19th century. The central focus is on the convergence of three mathematical topics: the hypergeometric and related linear differential equations, group theory, and on-Euclidean geometry. The text for this second edition has been greatly expanded and revised, and the existing appendices enriched with historical accounts of the Riemann–Hilbert problem, the uniformization theorem, Picard–Vessiot theory, and the hypergeometric equation in higher dimensions. The exercises have been retained, making it possible to use the book as a companion to mathematics courses at the graduate level.
Limnology and Aquatic Birds ; Proceedings of the Fourth Conference Working Group on Aquatic Birds of Societas Internationalis Limnologiae (SIL), Sackville, New Brunswick, Canada, August 3-7, 2003
The importance of habitat conservation for the protection of birds has become widely acknowledged and accepted by natural resource managers and the general public. Papers presented in this volume further our understanding of the important role that limnology has in determining habitat suitability for waterbirds. Long-term population monitoring of waterbirds is an important tool in our quest to understand the role waterbirds play in their environment. Continued population declines of many species of aquatic birds indicate the need for additional understanding of how human activities negatively impact water quality and bird populations and what mitigative actions can be taken. The main objective of the Working Group on Aquatic Birds of the International Limnological Society (SIL) is to integrate waterbirds into hydrobiology and treat waterbird studies in a limnological context. To achieve this goal, the Working Group organizes conferences to facilitate communications among limnologists interested in aquatic birds and ornithologists interested in the aquatic habitat. The efforts of the SIL Working Group on aquatic birds has resulted in a new emphasis on the links between aquatic birds and their environment
