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Clinical Neuroanatomy : A Neurobehavioral Approach
This book begins with a traditional review of the basic internal and external morphology, major nerve and fiber tracts, behavioral correlates, and clinical syndromes associated with spinal cord, brain stem, and cerebellum designed to reacquaint students and practicing clinicians with the functional anatomy of the subtentorial central nervous system. However, as the text was specifically geared to meet the needs of those practitioners whose primary interest is in what might be termed "higher order cognitive-behavioral function," the main focus of the text is on the brain itself. Borrowing heavily from a Lurian tradition, the central chapters reflect an attempt to offer more detailed, integrated, and, at times, theoretical models of cortical systems and their internal organization. Additional chapters highlight vascular anatomy and associated pathology, as well as neurochemical systems and their potential clinical relevance.
Clinical microbiology made ridiculously simple
Is a brief, clear, thorough, and updated approach to clinical microbiology, brimming with mnemonics, humor, summary charts, and illustrations. Topics include Ebola, AIDS, flesh-eating bacteria, mad cow disease, hantavirus, anthrax, smallpox, and tuberculosis; the latest antibiotics; pandemic flu, including H7N9; SARS-like coronavirus; hepatitis C treatment options; HIV diagnostics and approved HIV meds; Zika virus; measles; and a new chapter on the latest emerging infectious diseases and drug-resistant bacteria. The major update to this book is the addition of a new chapter on the SARS-COV-2 virus and COVID-19 disease, which delves into the nature of the virus such as infectivity within the body, transmission between individuals, timeline of infectivity, symptoms, risk factors, therapeutics, and vaccines approved for use.
Clinical cases in pediatric dentistry ; 2nd ed.
Features comprehensive updates to all 66 cases to include the latest diagnostic and treatment techniques. Each chapter also includes brand-new cases, for a total of 13 entirely new cases. The most current references to the literature, best practices, and evidence based clinical guidelines, plus new and updated self‐assessment questions with detailed answers and explanations, have been added to all the cases. Presents updated content, clinical guidelines, and references in existing cases, with thirteen brand new case scenarios Takes an easy-to-follow format, with patient history and diagnostics, questions, and answers, and explanations for each case Part of the "Clinical Cases" series applying both theory and practice to actual clinical cases Includes access to a companion website featuring additional case studies, charts, tables, web links, and the figures from the book in PowerPoint
Climatic Change and its Impacts : An Overview Focusing on Switzerland
This book focuses upon climate processes, variability and change and applies the general principles related to these issues, particularly in Switzerland. Although a small country, Switzerland is characterized by complex topography where climatic processes are often enhanced due to the presence of the Alps. In addition, there is a remarkable density of observational data in both the natural and social sciences that enable a comprehensive assessment of climate processes, their long-term trends and their impacts. This book is intended for students from the undergraduate level onwards and researchers interested in climate issues specific to the alpine region.
Class 2 Transferases I : EC 2.1.1
This new, second edition reflects considerable progress in enzymology: many enzymes are newly classified or reclassified. Each entry is correlated with references and one or more source organisms. New datafields are created: application and engineering (for the properties of enzymes where the sequence has been changed). The total amount of material contained in the Handbook has more than doubled so that the complete second edition consists of 39 volumes as well as a Synonym Index. In addition, starting in 2009, all newly classified enzymes are treated in Supplement Volumes. Springer Handbook of Enzymes is an ideal source of information for researchers in biochemistry, biotechnology, organic and analytical chemistry, and food sciences, as well as for medicinal applications
Class 2 · Transferases IV EC 2.4.1.1. -2.4.1.89 ; Vol.31
Springer Handbook of Enzymes provides data on enzymes sufficiently well characterized. It offers concise and complete descriptions of some 5,000 enzymes and their application areas. Data sheets are arranged in their EC-Number sequence and the volumes themselves are arranged according to enzyme classes. This new, second edition reflects considerable progress in enzymology: many enzymes are newly classified or reclassified. Each entry is correlated with references and one or more source organisms. New datafields are created: application and engineering (for the properties of enzymes where the sequence has been changed). The total amount of material contained in the Handbook has more than doubled so that the complete second edition consists of 39 volumes as well as a Synonym Index. In addition, starting in 2009, all newly classified enzymes are treated in Supplement Volumes.
Class 1 Oxidoreductases XI : EC 1.14.11 - 1.14.14
This new, second edition reflects considerable progress in enzymology: many enzymes are newly classified or reclassified. Each entry is correlated with references and one or more source organisms. New datafields are created: application and engineering (for the properties of enzymes where the sequence has been changed). The total amount of material contained in the Handbook has more than doubled so that the complete second edition consists of 39 volumes as well as a Synonym Index. In addition, starting in 2009, all newly classified enzymes are treated in Supplement Volumes. Springer Handbook of Enzymes is an ideal source of information for researchers in biochemistry, biotechnology, organic and analytical chemistry, and food sciences, as well as for medicinal applications.
Class 1 Oxidoreductases X : EC 1.9 - 1.13
This new, second edition reflects considerable progress in enzymology: many enzymes are newly classified or reclassified. Each entry is correlated with references and one or more source organisms. New datafields are created: application and engineering (for the properties of enzymes where the sequence has been changed). The total amount of material contained in the Handbook has more than doubled so that the complete second edition consists of 39 volumes as well as a Synonym Index. In addition, starting in 2009, all newly classified enzymes are treated in Supplement Volumes. Springer Handbook of Enzymes is an ideal source of information for researchers in biochemistry, biotechnology, organic and analytical chemistry, and food sciences, as well as for medicinal applications.
Children's diabetes
Diabetes in infants, toddlers, older children, and adolescents poses serious physical, mental, and emotional challenges. Striking a balance among hypoglycemia/hyperglycemia, growth/development, and other life factors is not easy for health care providers, patients, or families. In addition, personal, family, or environmental conditions present before the onset of diabetes may compound the delicate balance needed to maintain good glycemic control. Therefore, there is a great need, especially at the time of initial diagnosis, to assess the developmental, behavioral, and psychosocial history of children with diabetes and their families.
Childlessness in Europe : Contexts, Causes, and Consequences
This open access book provides an overview of childlessness throughout Europe. It offers a collection of papers written by leading demographers and sociologists that examine contexts, causes, and consequences of childlessness in countries throughout the region.The book features data from all over Europe. It specifically highlights patterns of childlessness in Germany, France, the United Kingdom, Finland, Sweden, Austria and Switzerland. An additional chapter on childlessness in the United States puts the European experience in perspective.
Chernobyl - What Have We Learned? : The Successes and Failures to Mitigate Water Contamination Over 20 Years
Twenty million people have been exposed to Chernobyl radionuclides through the Dnieper River aquatic pathways. This book presents a 20-year historical overview and comprehensive study results of the aquatic environment affected by the 1986 Chernobyl nuclear accident. During this time, many water quality management practices and countermeasures were enacted. The book presents in-depth analyses of these water remediation actions, using current science and mathematical modeling, and discusses why some were successful, but many others failed. The chapter entitled Where Do We Go From Here? incorporates a comprehensive discussion of the planned New Safe Confinement (NSC) structure to cover the Chernobyl plant. The book closes with a summary and conclusions drawn from these analyses, making it a valuable reference tool for the future. This book will be of interest to engineers, scientists, decision-makers, and those involved in radiation protection and radioecology, environmental protection and risk assessment, water remediation and mitigation measures, and radioactive waste disposal. In addition, the detailed, almost day-to-day, emergency responses to the Chernobyl accident described in this book will also be useful to people developing emergency and long-term responses to accidental or intentional (by terrorists) releases of radionuclides, toxic chemicals and biological agents.
Chance Rules : An informal guide to probability, risk and statistics
This second edition of Chance Rules again recounts the story of chance through history and the various ways it impacts on our lives. Here you can read about the earliest gamblers who thought that the fall of the dice was controlled by the gods, as well as the modern geneticist and quantum theory researcher trying to integrate aspects of probability into their chosen speciality. Example included in the first addition such as the infamous Monty Hall problem, tossing coins, coincidences, horse racing, birthdays and babies remain, often with an expanded discussion, in this edition. Additional material in the second edition includes, a probabilistic explanation of why things were better when you were younger, consideration of whether you can use probability to prove the existence of God, how long you may have to wait to win the lottery, some court room dramas, predicting the future, and how evolution scores over creationism. Chance Rules lets you learn about probability without complex mathematics.
Challenges to the second law of thermodynamics : Theory and experiment
The second law of thermodynamics is considered one of the central laws of science, engineering and technology. For over a century it has been assumed to be inviolable by the scientific community. Over the last 10-20 years, however, more than two dozen challenges to it have appeared in the physical literature - more than during any other period in its 150-year history. The number and variety of these represent a cogent threat to its absolute status. This is the first book to document and critique these modern challenges. Written by two leading exponents of this rapidly emerging field, it covers the theoretical and experimental aspects of principal challenges. In addition, unresolved foundational issues concerning entropy and the second law are explored. This book should be of interest to anyone whose work or research is touched by the second law.
Challenges and negotiations for women in higher education
There is much ambivalence in women’s experience of the academy as teachers and students. Although today many more women follow academic careers than in the past, they do not find the welcome that they had hoped for and expected. Additionally, women students find that whilst they can now enter through the doors of universities, academic space remains embedded in structures and cultures of gender and social class. This book is a clear and accessible exploration of lifelong learning and educational opportunities for women in higher education. It has been developed from work undertaken by members of the Women in Higher Education Network with chapters organised in three thematic sections: Ambivalent Positions in the Academy / Process and Pedagogy at Work / Career – Identity – Home
Cell therapy stem cells and regenerative medicine
Provides an overview of cell-based therapy for human diseases including the definition, history, and clinical applications of human stem cells and their use in regenerative medicine. It covers human pluripotent stem cells (human embryonic stem cells and human induced pluripotent stem cells), mesenchymal stem/stromal cells, and hematopoietic stem cells, bone marrow mononuclear cells. In terms of clinical applications, this book also provides an update on recent human trials using these cells to treat various diseases, including neurological disorders, pulmonary dysfunctions, metabolic/endocrine-related diseases, frailty, and cancer treatment. In addition, it discusses the authors’ clinical trial experiences related to these conditions in a clinical setting to provide additional insight into regenerative medicine, especially cell-based therapy.
Cell Division Control in Plants
The molecular mechanisms controlling cell cycle progression are highly conserved in eukaryotes. In addition to the basic protein machinery involved in cell cycle regulation, higher plants have also evolved unique molecular mechanisms that allow integration of environmental, physiological, and developmental signals into networks to control proper cell division and expansion. Rapid and exciting research progress in these fields has been achieved from experimental observations on plants over the past decade. The scope of this volume is focused on the molecular basis of all aspects of cell division and cytokinesis in plants. It is an essential reference book for instructors and scientists working in the areas of molecular, cell, and developmental biology of plants. The editors of this book are veterans in the field of plant molecular biology and highly respected worldwide.
Career options in the pharmaceutical and biomedical industry : An insider’s guide
Divided into five parts: Part 1 provides an academic perspective that focuses on the specific preparation required in the final years of study to embark on a successful career in the pharmaceutical and biomedical industries. In Part 2, industry experts discuss employment possibilities all along the drug or product life cycle,from discovery research and development to commercialisation. Part 3 follows, highlighting opportunities in support functions such as regulatory affairs or quality assurance. Part 4 focuses on additional opportunities in the wider biomedical sector, while Part 5 contains practical tips and training opportunities for entering the pharmaceutical and biomedical industries. In the epilogue, the authors reflect on this fascinating field and its career prospects.
Cardiac Safety of Noncardiac Drugs : Practical Guidelines for Clinical Research and Drug Development
The authors explain the parameters of cardiac safety at all stages of clinical research and drug development, including both the preclinical and pharmacogenomic aspects generally and the clinical methodologies and technical aspects for investigational drugs based on cardiac repolarization, as defined by the duration of the QTc interval. Additional chapters comprehensively review the application of electrocardiology in clinical research
Cardiac drug therapy
Cardiac Drug Therapy, 7th ed., addresses the pharmacology and therapeutic application of drugs used to treat heart diseases and hypertension. Additions and updates to the sixth edition include six new chapters on current controversies in cardiac drug therapy such as the beta blocker issue many cardiologists are presently grappling with. The book provides practical advice on how to manage cardiac diseases and addresses the choice of one particular cardiac agent vs. another. In addition to providing core knowledge in cardiovascular therapeutics, the text assists in resolving some of the issues surrounding cardiac drugs. Cardiac Drug Therapy provides practical information including properties, dosage, side effects, potential salutary benefits, and drawbacks on virtually all commercially available cardiac drugs.
Carbon monoxide in drug discovery, basics, pharmacology, and therapeutic potential
Carbon monoxide, one of the smallest organic natural molecules, is widely known for its toxicity. Formation of CO via incomplete combustion is a major contributing factor to accidental or intentional CO poisoning, leading to severe health consequences or death. In addition, CO is a by-product of tobacco smoking, and has been associated with some of the harmful effects of smoking. However, less known and probably far more important is the recognition of the essential physiological roles of CO as a signaling molecule in mammals. Against over more than a century of negative connotation, the last few decades have proven that CO possesses a multitude of physiological roles and therapeutic functions including regulation of the immune response, cellular proliferation, and control of cell survival. This concept is supported by the discovery that CO is produced by all cells and more so under conditions of stress. This book comprehensively summarizes key aspects of CO's endogenous roles, therapeutic functions, and challenges that we face in its development as a therapeutic agent. We hope this preface will provide a thread for reading this book and a birds-eye view of the landscape for understanding this field, and more importantly lay out the challenges ahead in understanding the detailed mechanisms of action of CO and in its development as a therapeutic agent.
