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The Pendulum : Scientific, Historical, Philosophical and Educational Perspectives
The pendulum is a universal topic in primary and secondary schools, but its full potential for learning about physics, the nature of science, and the relationships between science, mathematics, technology, society and culture is seldom realised.Contributions to this 32-chapter anthology deal with the science, history, methodology and pedagogy of pendulum motion. There is ample material for the richer and more cross-disciplinary treatment of the pendulum from elementary school, to high school, and through to advanced university classes.
The Pathophysiologic Basis of Nuclear Medicine
Deals with molecular imaging. This book includes a separate chapter on the basis of FDG uptake, and offers clinically oriented details on scintigraphic studies, their strengths and limitations in relation to other modalities. It also contains images, illustrations and tables.
The Papillomaviruses
This volume reviews the remarkable confluence of science, medicine, and public health that recently culminated in the approval of vaccines that prevent many human papillomavirus infections, the first vaccines specifically designed to prevent human cancer. Basic laboratory studies of viral DNA replication, gene expression, protein function, and virus-host interactions have provided fundamental insights into these important processes.
The Palgrave Handbook of Twentieth and Twenty-First Century Literature and Science
Illustrates the evolution of literature and science, in collaboration and contestation, across the twentieth and twenty-first centuries. The essays it gathers question the charged rhetoric that pits science against the humanities while also demonstrating the ways in which the convergence of literary and scientific approaches strengthens cultural analyses of colonialism, race, sex, labor, state formation, and environmental destruction.
The Palgrave Handbook of Positive Education
This handbook provides a comprehensive overview of the growing field of positive education, featuring a broad range of theoretical, applied, and practice-focused chapters from leading international experts. It demonstrates how positive education offers an approach to understanding learning that blends academic study with life skills such as self-awareness, emotion regulation, healthy mindsets, mindfulness, and positive habits, grounded in the science of wellbeing, to promote character development, optimal functioning, engagement in learning, and resilience.
The Palgrave Handbook of Critical Menstruation Studies
This handbook, the first of its kind, provides a comprehensive and carefully curated multidisciplinary genre-spanning view of the state of the field of Critical Menstruation Studies, opening up new directions in research and advocacy. It is animated by the central question: ‘“what new lines of inquiry are possible when we center our attention on menstrual health and politics across the life course?” The chapters—diverse in content, form and perspective—establish Critical Menstruation Studies as a potent lens that reveals, complicates and unpacks inequalities across biological, social, cultural and historical dimensions.
The p53 Tumor Suppressor Pathway and Cancer
The current year (2004) marks the Silver Anniversary of the discovery of the p53 tumor suppressor. The emerging ?eld ?rst considered p53 as a viral antigen and then as an oncogene that cooperates with activated ras in transforming primary cells in culture. Fueling the concept of p53 acting as a transforming factor, p53 expression was markedly elevated in various transformed and tumorigenic cell lines when compared to normal cells. In a simple twist of fate, most of the studies conducted in those early years inadvertently relied on a point mutant of p53 that had been cloned from a normal mouse genomic library. A bona ?de wild-type p53 cDNA was subsequently isolated, ironically, from a mouse teratocarcinoma cell line. A decade after its discovery, p53 was shown to be a tumor suppressor that protects against cancer. It is now recognized that approximately half of all human tumors arise due to mutations within the p53 gene. As remarkable as this number may seem, it signil cantly underrepresents how often the p53 pathway is targeted during tumorigenesis. It is my personal view, as well as many in the p53 ?eld, that the p53-signaling pathway is corrupted in nearly 100% of tumors. If you are interested in understanding cancer and how it develops, you must begin by studying p53 and its pathway. After demonstrating that p53 functions as a tumor suppressor the ?eld exploded and p53 became a major focus of scientists around the world.
The Oxford handbook of police and policing
The different sections of the Handbook explore policing contexts, strategies, authority, and issues relating to race and ethnicity. The Handbook also includes reviews of the research methodologies used by policing scholars and considerations of the factors that will ultimately shape the future of policing, Aimed at a wide audience of scholars and students in criminology and criminal justice
The oxford handbook of comparative law
The Handbook contains forty two chapters which are written by experts from around the world. The aim of each chapter is to provide an accessible, original, and critical account of the current state of comparative law in its respective area which will help to shape the agenda in the years to come. Each chapter also includes a short bibliography referencing the definitive works in the field
The Outer Planets and their Moons : Comparative Studies of the Outer Planets prior to the Exploration of the Saturn System by Cassini-Huygens
This volume gives an integrated summary of the science related to the four giant planets in our solar system. It is the result of an ISSI workshop on «A comparative study of the outer planets before the exploration of Saturn by Cassini-Huygens» which was held at ISSI in Bern on January 12-16, 2004. Representatives of several scientific communities, such as planetary scientists, astronomers, space physicists, chemists and astrobiologists have met with the aim to review the knowledge on four major themes: (1) the study of the formation and evolution processes of the outer planets and their satellites, beginning with the formation of compounds and planetesimals in the solar nebula, and the subsequent evolution of the interiors of the outer planets, (2) a comparative study of the atmospheres of the outer planets and Titan, (3) the study of the planetary magnetospheres and their interactions with the solar wind, and (4) the formation and properties of satellites and rings, including their interiors, surfaces, and their interaction with the solar wind and the magnetospheres of the outer planets.
The Origins of Language : Unraveling Evolutionary Forces
Developments in cognitive science indicate that human and nonhuman primates share a range of behavioral and physiological characteristics that speak to the issue of language origins. This volume has three major themes, woven throughout the chapters. First, it is argued that scientists in animal behavior and anthropology need to move beyond theoretical debate to a more empirically focused and comparative approach to language. Second, those empirical and comparative methods are described, revealing underpinnings of language, some of which are shared by humans and other primates and others of which are unique to humans. New insights are discussed, and several hypotheses emerge concerning the evolutionary forces that led to the "design" of language. Third, evolutionary challenges that led to adaptive changes in communication over time are considered with an eye toward understanding various constraints that channeled the process.
The Oceanic Thermohaline Circulation : An Introduction
In this book different aspects of the oceanic thermohaline circulation, the dominant meridionally overturning mode of the global ocean circulation, are presented. The topics, presented in this book, are the aspects of thermodynamics of seawater and geophysical fluid dynamics that are important for the understanding of this current system, basic observational hydrographic methods to study the thermohaline circulation, and a description of the thermohaline circulation, based on observational evidence. This includes the deep circulation in the abyssal basins, global deep upwelling, the shallow return flow to high latitudes, and the formation and descent of high-density deep water masses in these cold regions. This book is intended to be used by advanced undergraduates and graduate students in physical oceanography, climatology, geography and environmental sciences, paleoceanography, marine biology and marine chemistry.
The Nuclear Imperative : A Critical Look at the Approaching Energy Crisis
In this well documented global wake-up call, nuclear physicist Jeff Eerkens explores remedies for the impending energy crisis, when oil and natural gas are depleted. Because burning coal worsens the problem ofglobal warming, alternate energy sources must be instituted. The Nuclear Imperative demonstrates with scientific documentation that solar, wind, and biomass power, while helpful, are incapable of supplying and sustaining the enormous quantities of electricity and heat needed for manufacturing portable synthetic fuels (synfuels) to replace our current use of fossil fuels. Instead, it offers a fresh look at uranium-produced energy as the optimal affordable solution.
The New Retirement : The Ultimate Guide to the Rest of Your Life
The book includes surveys, questionnaires, and worksheets to help readers understand and apply the critical steps affecting retirement planning.
The new Innovation of paracetamol
Active pharmaceutical ingredients (APIs) may exist in various solid forms, which can lead to differences in the intermolecular interactions, Differences in solid forms often lead to differences in thermodynamic parameters and physicochemical properties for example solubility (especially that a lot of drugs are in Class II and IV according to BCS (Biopharmaceutics Classification System) and these classes suffer from poor aqueous solubility and hence low bioavailability},dissolution rate, stability and mechanical properties of APIs and excipients...
The new in peptic ulcer
Peptic ulcer can be defined as mucosal lesions that penetrate the muscularis mucosae layer and form a cavity surrounded by acute and chronic inflammation. It continues to be a source of significant morbidity and mortality worldwide. Approximately two-thirds of patients found to have peptic ulcer disease are asymptomatic. In symptomatic patients, the most common presenting symptom of peptic ulcer disease is epigastric pain, which may be associated with dyspepsia, bloating, abdominal fullness, nausea, or early satiety.
The new histories of international criminal law : retrials
Has considerable traction in global politics, and much of its legitimacy is embedded in apparently 'axiomatic' historical truths. This innovative edited collection brings together some of the world's leading international lawyers with a very clear mandate in mind: to re-evaluate ('retry') the dominant historiographical tradition in the field of international criminal law.
The new astronomy : Opening the electromagnetic window and expanding our view of planet earth : A Meeting to Honor Woody Sullivan on his 60th Birthday
This unique work celebrates the 60th birthday of Professor Woodruff Sullivan III (University of Washington, Seattle). The ‘Woodfest’ conference attracted some of the world’s leading astrobiologists and historians of astronomy, so it is no surprise this book provides a collection of key papers and reviews on the history of astronomy, astrobiology and sundials. The emphasis on radio astronomy in the historical papers is a fitting reminder that Woody is widely acknowledged as the world’s leading authority in this field. But there are also papers on astrobiology, which reflect his intimate involvement in this exciting multidisciplinary field. The papers on sundials reveal another passion and his quest to make Seattle the sundial capital of North America! This book will appeal to professional and amateur astronomers, and is a tribute to one of the world’s most remarkable astronomers.
The NeurIPS '18 Competition : From Machine Learning to Intelligent Conversations
This volume presents the results of the Neural Information Processing Systems Competition track at the 2018 NeurIPS conference. The competition follows the same format as the 2017 competition track for NIPS. Out of 21 submitted proposals, eight competition proposals were selected, spanning the area of Robotics, Health, Computer Vision, Natural Language Processing, Systems and Physics. Competitions have become an integral part of advancing state-of-the-art in artificial intelligence (AI). They exhibit one important difference to benchmarks: Competitions test a system end-to-end rather than evaluating only a single component; they assess the practicability of an algorithmic solution in addition to assessing feasibility.
The mystery of Tamoxifen
Selective estrogen receptor modulators (SERMs) have been shown to reduce the risk of developing estrogen-positive breast cancer. Tamoxifen, a potent SERM, has been successfully administered as adjuvant therapy for breast cancer. However, uterine pathologic changes may develop due to the effect of tamoxifen as both an agonist and antagonist of estrogen on the uterus. Here, we discuss a case of breast cancer treated with tamoxifen to clarify one of the most important complications, namely, endometrial hyperplasia.
