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Lentil : An ancient crop for modern times
Presents the most comprehensive and up to date review of research on lentil production systems, biotic and abiotic stresses management, quality seed production, storage techniques and lentil growing around the world. This book will be of great value to legume breeders, scientists, nutritionists, academic
Lemurs : Ecology and Adaptation
In this comprehensive volume, written by experts in the field, information gathered on lemur ecology and adaptation over the past 15 years is presented by both seasoned and newer lemur researchers, and provides us with further knowledge concerning both well-studied and rarely studied extant species, as well as insights into the ecology and adaptation of some of the recently extinct lemurs.
Left-right asymmetry in vertebrate development
A host of studies has unravelled the involvement of many genes in the left right patterning pathway. Based on this knowledge the genetic basis of human laterality defects are beginning to be revealed. It is a major challenge now to understand how all these genes control left right development as well as the complex set of interactions established between them.
Lectins
In the intervening years well over 10,000 articles have appeared with lectins as the main subject, and more than twice as many in which they were touched upon, as well as around 20 books. In particular, great strides have been made in several areas of lectin research, about which little was known until the late 1980s. One prominent example is animal lectins, many of which have been discovered only during the last decade and the functions of several of which have been clarified, especially as to their key role in innate immunity.
Le Distilbène trente ans après : Les enfants des 2èmes et 3èmes générations = Distilbene thirty years later : The children of the 2nd and 3rd generations
The various consequences on the anatomy and physiology of the female genitalia, as well as male, of children exposed in utero are reviewed. The impact on girls is greater than on boys: modification of the uterine cervix, reduction in the volume of the uterus with its consequences on fertility and the progress of pregnancies, risk of cancer of the vagina and the cervix. . The potential repercussions on the third generation are analyzed from experimental studies. Finally, the medico-legal implication is studied from the various trials that took place in the United States and from the first French trial that took place in Nanterre in November 2003. This work is the result of the collaboration of several experts recognized for their competence in this field. It will be of interest to all obstetrician gynecologists, urologists, but also public health physicians and midwives.
Le dépistage du cancer du sein : un enjeu de santé publique = Breast cancer screening: a public health issue
Fifteen years after the first experiments, the breast cancer screening program was rolled out in France in 2004. It is aimed at more than eight million women aged 50 to 74. Public health action on such a scale is exemplary in Europe and especially in France where the health system is not centralized. The new edition of this book takes stock of the current state of the program and its initial results. It updates technical and radiological aspects, assessment indicators, communication and forensic problems and finally the progress of foreign programs. The history of the French program is detailed from the 1990s until 2006, with the publication of the latest version of the specifications by the Directorate General of Health. The short and medium term objectives are re-specified: to increase the participation of women, to retain them and to further improve the quality of practices. The challenge is to combine the performance of screening and therapeutic management to finally achieve a clear reduction in mortality, which has remained stable for twenty years.
Le cancer du sein = Breast cancer
The reader will find there both a synthetic summary of the current state of knowledge of epidemiology, risk factors and pathological aspects as well as a presentation of the surgical aspects, in particular, of the new approach that constitutes the sentinel node procedure. Radiotherapy, in a practical view, is divided into essential clinical questions. The medical treatment is then discussed according to the different situations encountered on a daily basis. Particular attention is of course paid to recent data both with the contribution of hormone therapy and targeted therapies. Finally, the symptomatic treatments and especially the psychological care of these patients are not forgotten.
Latency Strategies of Herpesviruses
This is the first book dealing with the intricate epigenetic mechanisms (DNA methylation, histone modification, alteration of chromatin structure) that regulate latency-associated transcription. Special attention is given to immune evasion "tricks" blocking immune responses to herpesvirus infected cells and viral RNAs and proteins involved in malignant transformation.
Lassativi : Impiego razionale dei lassativi nella stipsi = assatives : Rational use of laxatives in constipation
An extensive compendium on laxatives. It covers all aspects of the clinical use of laxatives complete with physiological information related to constipation. The mechanisms of action of the main classes of laxatives are widely described. The text contains illustrations that help to understand the origins of plant laxatives and the pharmacology of the most interesting ones. Doctors, pharmacists, herbalists, nurses and students will find this volume interesting and useful.
Landscape Pattern Analysis for Assessing Ecosystem Condition
Landscape Pattern Analysis for Assessing Ecosystem Condition presents a new method for assessing spatial pattern in raster land cover maps based on satellite imagery in a way that incorporates multiple pixel resolutions. This is combined with more conventional single-resolution measurements of spatial pattern and simple non-spatial land cover proportions to assess predictability of both surface water quality and ecological integrity within watersheds of the state of Pennsylvania (USA).
Landscape Ecological Applications in Man-Influenced Areas : Linking Man and Nature Systems
This book also includes several case studies concerning landscape analysis and evaluation using spatial analysis and landscape modelling for establishing sustainable management strategy in urban and agricultural landscapes. The subtitle of the book suggests the integrative and ubiquitous landscape planning considering harmony of man and nature systems in the socio-economic and cultural background.
La scuola dell’atopia = The school of atopy
The need to clarify the current concepts of atopy, which for too long have oscillated between a primitive purely clinical vision and a subsequent purely immunological one, had been ripe for some time. Understanding that the role of immunoglobulins E is not exhaustive and accepting the Solomonic division between intrinsic and extrinsic atopy were the first two fundamental steps. Recent discoveries of the role of innate immunity, and therefore of antimicrobial peptides, have opened fundamental spaces for understanding in atopy and beyond. What now appears clear is that atopy is not the disease of an organ but rather a defect in the membranes that delimit our "self". The fact that these membranes are called skin, intestines, conjunctiva, bronchi or whatever has artificially fragmented the understanding and treatment of a unitary phenomenon. This book seeks to summarize the different experiences but above all to be a stimulus to ensure that medicine focuses constructively on the same target. If this is the case, we will no longer see "religious wars" between scientists and practicing doctors or, even worse, between the different specialists vying for the patient. If atopy, as we believe, is a global problem, it can only be adequately addressed in a multidisciplinary context and in a collaborative atmosphere, not only between doctor and doctor but also between doctor and patient.
La riabilitazione dei disturbi cognitivi nella sclerosi multipla = The rehabilitation of cognitive disorders in multiple sclerosis
Multiple sclerosis is one of the most frequent causes of chronic disability in young adults. It mainly affects individuals between 20 and 50 years of age, with a peak of incidence around the age of 30. This disease is characterized by the presence of demyelinating lesions of an inflammatory nature disseminated in the central nervous system. The different localization of these lesions is at the basis of the variability of clinical symptoms which can be characterized by motor, sensory, neurovegetative and cognitive disorders. The latter concern about half of the patients affected by this pathology and have a significant impact on the personal, family and work situation of these patients.
La respirazione artificiale : Basi e pratica = The artificial respiration: Basi e pratica
Mechanical respiration is a procedure with an intensive medicine physician and specialized specialist in the discipline of general medicine if I must daily confront. The volume is described in detail and foundation of the clinical practice: starting from the basic anatomy and physiology of the mechanical respiration and the variety of forms of respiratory insufficiency. metodi alternativi and il management delle malattie specifiche dell'apparato respiratorio. We are here to discuss the latest technology for respiratory therapy and non-invasive mechanical respiration.
La réanimation neurochirurgicale = Neurosurgical resuscitation
«decade of the brain », s’est ajouté en clinique humaine le développement des nouvelles techniques d’imagerie. Ceci a permis d'enterrer enfin certaines idées anciennes et de développer de nouvelles stratégies thérapeutiques fondées sur une meilleure compréhension des mécanismes physiopathologiques de l’agression cérébrale en transposant les résultats de la recherche fondamentale dans la pratique de tous les jours. Il ne fait aucun doute que le médecin, qu'il soit anesthésiste, réanimateur, urgentiste, qui serait passé « à côté » de cette période concernant la prise en charge globale du cerveau agressé se retrouverait distancé face à la prise en charge actuelle et n’aurait pas en main les moyens d’en comprendre sa justification. L’association de neuro-anesthésie réanimation de langue Française
La phytocosmétologie thérapeutique = Herapeutic phytocosmetology
Deals with restorative cosmetology. This is understood through the eyes of the doctor specializing in phytotherapy. Three main aspects are discussed: the diagnosis of disturbance of the skin and integuments, external treatment with natural substances, as well as oral treatment (internal treatment). Oral cosmetology has no official recognition, yet the effects of plant extracts on the condition of the skin and integuments are well known. After an introduction to the physiology of the skin, the dosage and the phenomena of skin deterioration, the author discusses different types of treatment depending on the extracts used while explaining their mode of action. This work was written by a doctor, Doctor Paul Goetz, teacher in clinical phytotherapy, and a pharmacist, Doctor Christian Busser, pharmaceutical and scientific advisor, doctor in ethnology and ethnopharmacologist.
La lombalgie en 2007 : Aspects pratiques = Low back pain in 2007 : Practical aspects
Low back pain is one of the main reasons for consultation, whether in general or specialized medicine. It poses a real public health problem. This "back pain", which can despair patients and doctors by its sometimes rebellious character, explains the multiplicity of examinations sometimes practiced and the treatments implemented. This work is a collection of the most recent developments in terms of physiopathological knowledge of disc involvement, clinical examination and the place of surgery and in particular disc prostheses. An update concerns the indications and contributions of additional examinations; some formidable diagnostic traps are mentioned. Medical treatments such as infiltrations, manipulations, the benefit of restraints and the provision of acupuncture are being developed. Also discussed are the latest scientific data on isokinetic evaluation and retraining, as well as the role of sports activity as a factor in the prevention or aggravation of low back pain. Finally, the medico-legal aspect is dealt with in the context of work accidents, and the assessment after trauma. This book is the result of the collaboration and experience of undisputed specialists in this field.
L’insuffisance rénale aiguë = Acute renal failure
The aim of this book is to make current data from the experimental and clinical literature accessible to readers. More than a thousand articles are published each year on the theme and the authors aim to synthesize this information. These data relate in particular to the identification of early markers of renal dysfunction without which screening, recognition of the main pathophysiological determinants and prevention remain uncertain. This book focuses attention on clinical situations characterized by the renal impact of the main dysfunctions of vital functions, the prognosis of which is worsened by the occurrence of this renal failure. The following will be treated in particular: the renal consequences of oxidative stress, the renal consequences of respiratory dysfunction, cardiac dysfunction, hepatic dysfunction, alterations in hemostasis, septic shock and hemorrhagic shock. Finally, the physiopathological data from experimental models are gradually finding their echo in the clinical field, opening up therapeutic avenues whose recent evaluations will be analyzed.
Key Clinical Trials in Erectile Dysfunction
Represents a critical appraisal of the major clinical trials that have had a significant impact on clinical research and practice during the last decade. Each trial follows a strict format, starting with reference to the original source of publication, details on the key investigators and their methods of research. The strengths and weaknesses of each trial are discussed as well as their influence on clinical practice. Articles are complemented by a diagrammatic summary of the trial design and the key findings.
Kaposi Sarcoma Herpesvirus : New Perspectives
Since the identificationof two sequences fromKSHV,wehave learnedmuch about this pathogen as reflected in this book. As it turned out, KSHV itself encodes for a number of cytokines, and induces cellular cytokine secretion, contributing to tumour growth. Moreover, KSHV vFLIP targets the IKKNFκB axis to encourage the inflammatory microenvironment observed by Gallo and his colleagues. KSHV continues to elucidate both mechanisms of viral oncogenesis, and cellular and immune pathways involved in non-viral driven neoplasia.
