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Nanostructured Materials by High-Pressure Severe Plastic Deformation

Recently, it was reported that nanostructured materials processed under high pressure by HPT and ECAP have an extraordinary combination of both high strength and high ductility, which are two desirable, but rarely co-existing properties. These findings indicate that high-pressure is a critical factor that can be employed to process nanostructured materials with superior mechanical, and possibly also physical, properties. It is the objective of this workshop to review our current knowledge, identify issues for future research, and discuss future directions on the processing and properties of nanostructured materials via SPD techniques, with a special emphasis on high-pressure effects.

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Nanostructured Coatings

Controlling the performance of structures and components of all sizes and shapes through the use of engineered coatings has long been a key strategy in materials processing and technological design. The ever-increasing sophistication of en- neered coatings and the rapid trend toward producing increasingly smaller devices with greater demands on their fabrication, properties and performance have led to signicant progress in the science and technology of coatings, particularly in the last decade or two. Nanostructured coatings constitute a major area of sci- ti?c exploration and technological pursuit in this development.Nanostructured coatings demand study in a highly interdisciplinary research arena which encompasses: surface and interface science study of defects modern characterization methodologies cutting-edge experimental developments to deposit.

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Nanostructured and advanced materials for applications in sensor, optoelectronic and photovoltaic technology ; Proceedings of the NATO Advanced Study Institute on nanostructured and advanced materials for applications in sensors, optoelectronic and photovoltaic technology ; Sozopol, Bulgaria, 6-17 September 2004

Nanotechnology is an emerging scientific field receiving significant worldwide attention. On a nanometer scale, materials or structures may possess new and unique physical properties. Some of these are now known to the scientific community, but there may well be many properties not yet known to us, rendering it as a fascinating area of research and a suitable subject for a NATO ASI. Yet another aspect of the field is the possibility for creating meta-stable phases with unconventional properties and the ultra-miniaturization of current devices, sensors, and machines. Such nanotechnological and related advanced materials have an extremely wide range of potential applications, viz. nanoscale electronics, sensors, optoelectronics, photonics, nano-biological systems, na- medicine, energy storage systems, etc. This is a wide-ranging subject area and therefore requires the formation of multi-disciplinary teams of physicists, chemists, materials scientists, engineers, molecular biologists, pharmacologists, and others to work together on the synthesis and processing of materials and structures, the understanding of their physical properties, the design and fabrication of devices.

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Nanoscaled Semiconductor-on-Insulator Structures and Devices

This proceedings volume constitutes an archive of the contributions of the key-speakers who attended the NATO Advanced Research Workshop on “Nanoscaled Semiconductor-On-Insulator Structures and devices” held in the Tourist and Recreation Centre “Sudak” (Crimea, Ukraine) from 15 to 19 October 2006. The semiconductor industry has sustained a very rapid growth during the last three decades through impressive technological developments which have resulted in products with higher performance and lower cost per function. After many years of development it is now confidently predicted that semiconductor-on-insulator materials will enter and increasingly be used by manufacturing industry. The wider use of semiconductor (es- cially silicon) on insulator materials will not only enable the benefits of these materials to be demonstrated but, also, will drive down the cost of substrates which, in turn, will stimulate the development of other novel devices and applications.

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Nanoscale Transistors : Device Physics, Modeling and Simulation

The book is a useful reference for senior-level or graduate-level courses on nanoelectronics, modeling and simulation. Chapter 1 reviews some basic concepts, and Chapter 2 summarizes the essentials of traditional semiconductor devices, digital circuits, and systems. This material provides a baseline against which new devices can be assessed. Chapters 3 and 4 present a non-traditional view of the MOSFET using concepts that are valid at nanoscale. Chapter 5 applies the same concepts to nanotube FET as an example of how to extend the concepts to revolutionary nanotransistors. Chapter 6 explores the limits of devices by discussing conduction in single molecules.

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Nanoscale Phenomena : Basic Science to Device Applications

Nanotechnology is the result of the continuing technological trend toward device miniaturization and the characterization, manipulation, and fine control of structure and function at diminishing length scales. A large class of nanoscale materials can be stable even though they are far from the lowest-energy thermodynamic state, and many possess novel properties unattainable in bulk. These trends are supported by the increasing sophistication of characterization and fabrication tools such as the scanning tunneling microscope and the transmission electron microscope, which allow the resolution and manipulation of single atoms and molecules.

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Nanoscale Assembly : Chemical Techniques

Recent advances have pushed the limits of lithography firmly into the sub-100 nm domain, with smallest feature sizes around 10 nm. However, compared to living organisms, devices fabricated using nanolithography are not nearly as complex, as they are essentially 2D and contain only a limited number of chemical elements. For centuries, Nature has been a major inspiration for science. First of all to learn how Life functions at cellular level, but increasingly, as a blueprint for designing non-natural devices where the building blocks and their assembly are inspired by biological examples. The key tool in translating these examples into the domain of engineering, has been self-assembly or self-organization. This book gathers a spectrum researchers who have not only furthered our knowledge of self-assembly using small molecules, polymers and colloidal particles as building blocks, but who have also shown it to be a practical tool in the assembly of an astonishing variety of devices, ranging from molecular electronics to biosensors.

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Nanopharmaceuticals ; Vol.1 : Expectations and realities of multifunctional drug delivery systems

Reviews advances in the drug delivery field via nanovehicles or nanocarriers that offer benefits like targeted therapy and serves as a single dose magic bullet for multiple drug delivery with improved drug efficiency at a lower dose, transportation of the drug across physiological barriers as well as reduced drug-related toxicity. The chapters are written by a diverse group of international researchers from industry and academia. The series Expectations and Realities of Multifunctional Drug Delivery Systems examines the fabrication, optimization, biological aspects, regulatory and clinical success of wide range of drug delivery carriers. This series reviews multifunctionality and applications of drug delivery systems, industrial trends, regulatory challenges and in vivo success stories. Throughout the volumes discussions on diverse aspects of drug delivery carriers, such as clinical, engineering, and regulatory, facilitate insight sharing across expertise area and form a link for collaborations between industry-academic scientists and clinical researchers. Expectations and Realities of Multifunctional Drug Delivery Systems connects formulation scientists, regulatory experts, engineers, clinical experts and regulatory stake holders. The wide scope of the book ensures it as a valuable reference resource for researchers in both academia and the pharmaceutical industry who want to learn more about drug delivery systems.

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Nanopharmaceuticals : Vol.3 : Principles and applications

Focuses on the recent advances of nanopharmaceuticals in cancer, dental, dermal and drug delivery applications and presents their safety, toxicity and therapeutic efficacy. The book also includes the transport phenomenon of nanomaterials and important pathways for drug delivery applications. It goes on to explain the toxicity of nanoparticles to different physiological systems and methods used to assess this for different organ systems using examples of in vivo systems.

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Nanoparticles in Biomedical Imaging : Emerging Technologies and Applications

Fundamental Biomedical Technologies features titles in multidisciplinary, technology-driven areas, providing the foundations for breakthrough advances in medicine and biology. The term technology refers, in a vigorously unrestrictive sense, to a broad array of engineering disciplines, the sciences of computation and informatics, mathematical models exploiting and advancing methods of mathematical physics, and the development of novel, experimental discovery devices. Titles in this series are designed and selected to provide high-level visionary input for specialists, while presenting overviews of emerging fields for those in related areas. Volumes in this series aim to provide technologists with the material to gain competent entry into biomedical research and biomedical researchers to understand and embrace novel technological foundations and tools.

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Nanoparticle-Based Drug Delivery in Cancer Treatment

Discusses nanotechnological developments of interfering RNA-based nanoparticles, delivery vehicles, and validated therapeutic RNAi–molecular target interactions and explains the results of clinical and preclinical trials. The book also gives strategies for universal methods of constructing hybrid organic–inorganic nanomaterials that can be widely applied in the biomedical field. Focuses on : Recent advances of nanoparticle-mediated siRNA delivery systems and their application in clinical trials for cancer therapy Material platforms that establish NPs and both localized and controlled gene silencing The most promising systems for clinical application Surveys progress in nanoparticle-based nanomedicine in cancer treatment The most advanced of the nonviral nanocarriers for delivery of oligonucleotides to malignant blood cancer cells

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Nanomedicine : Innovations, applications, and breakthroughs in the quest for health and medicine's future

Revolutionizing healthcare, by providing innovative solutions to some of the most challenging issues in medicine. This book provides an in-depth overview of nanoscale materials and devices that are advancing diagnostics, therapeutics, and personalized care in medical field. It focuses on nanomedicine’s impact on vaccine efficacy as well as innovative diagnosis and therapy for various type of cancer while addressing concerns about safety and toxicity. It examines how nanotechnology is enhancing drug delivery by precisely targeting medicines to specific cells or tissues, thereby increasing treatment efficacy with reduced side effects. Explores how nanoparticles are advancing medical imaging for earlier and more accurate disease detection, and how nanosensors allow real-time biomarker monitoring for faster and more reliable diagnoses. Additionally, it explores nanomedicine's role in managing cardiovascular diseases, improving bone health through nano-extracellular vesicles, and regenerative medicine, including ongoing clinical trials and ethical considerations.

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Nanomaterials for Application in Medicine and Biology

This volume contains research reports presented during the NATO Advanced Research Workshop (ARW) “Materials for Application in Medicine and Biology” held in Bonn, Germany, from October 4 to 6, 2006 at the center of advanced european studies and research (caesar). The application of nanomaterials in medicine and biology can be understood as the gathering and use of our current knowledge on nanoscale features of b- logical systems in order to learn how to design nanodevices for biomedical uses.

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Nanomaterials and Nanosystems for Biomedical Applications

The book includes expert reviews on the advances and current problems associated with the implants and nanodevices along with their applications in medicine, pharmaceutics, cancer therapy, gene transfer and drug delivery. The editor, M. R. Mozafari (PhD), has been working in the field of nanobiotechnology for the past 14 years and has produced more than 60 publications.

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Nanomaterials and Nanochemistry

Nanomaterials are a fast developing field of research and applications lie in many separate domains, such as in hi-tech (optics, electronics, biology, aeronautics), but also in consumer industries (automotive, concrete, surface treatments (including paints), cosmetics, etc.).

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Nanoinformatics

Brings out the state of the art on how informatics-based tools are used and expected to be used in nanomaterials research. There has been great progress in the area in which “big-data” generated by experiments or computations are fully utilized to accelerate discovery of new materials, key factors, and design rules. Data-intensive approaches play indispensable roles in advanced materials characterization. "Materials informatics" is the central paradigm in the new trend. "Nanoinformatics" is its essential subset, which focuses on nanostructures of materials such as surfaces, interfaces, dopants, and point defects, playing a critical role in determining materials properties. There have been significant advances in experimental and computational techniques to characterize individual atoms in nanostructures and to gain quantitative information. The collaboration of researchers in materials science and information science is growing actively and is creating a new trend in materials science and engineering.

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Nanocomposites : Ionic Conducting Materials and Structural Spectroscopies

Nanocomposites have been receiving more and more attention given the improvement of synthesis techniques and the availability of powerful characterization techniques. The aim of the book is to introduce nanocomposite materials using a broad range of inorganic and organic solids. Furthermore, it is intended to present recent and not very common developments in especially spectroscopic characterization techniques, including Mössbauer, EXAFS, NMR. This should make the book attractive for a broad range of readers, including chemists and physicists.

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Nanocatalysis

Nanocatalysis is one of the most exciting subfields to have emerged from nanoscience. Its central aim is the control of chemical reactions by changing the size, dimensionality, chemical composition and morphology of the reaction center and by changing the kinetics using nanopatterning of the reaction centers. This approach opens up new avenues for atom-by-atom design of nanocatalysts with distinct and tunable chemical activity, specificity, and selectivity. This book is intended to give a pedagogical and methodological overview of this exciting and growing field and to highlight specific examples of current research. In this way, it serves both as an instructive introduction for graduate students who plan to enter the field and as a reference work for scientists already active in this and related areas.

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Nanocarrier Technologies : Frontiers of Nanotherapy

Nanobiotechnology is one of the key technologies of the 21st century. It is a combination of nanoscience and biotechnology and covers areas ranging from gene transfer and nanoencapsulation to food technology. Nanocarriers are a leading nanobiotechnology tool with the ability to provide protection, site-specific delivery, enhanced bioavailability and controlled release of pharmaceuticals, genetic material, imaging agents, nutraceuticals and cosmetics to name a few. For this reason, the study of nanocarriers, their properties and applications has attracted a great deal of interest over recent years. Designed as an advanced survey of the field, this book describes the key research parameters of nanocarrier technologies including their preparation methods, evaluation of their safety and efficiency, their interaction with biologicals and their application in biotechnology, drug delivery, gene therapy and food technology areas.

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NanoBiotechnology : BioInspired Devices and Materials of the Future

NanoBioTechnology: BioInspired Devices and Materials of the Future is a groundbreaking text that will assist scientists and students in learning the fundamentals and cutting-edge nature of this new and emerging science. Focusing on materials and building blocks for nanotechnology, leading scientists from around the world share their knowledge and expertise in this authoritative volume. The volume is broken into five sections. The first section presents an overview of nanotechnology and describes the many aspects of the field. Section 2 details biological materials serving as nanotemplates for bottom-up fabrication. Section 3 covers the use of biological macromolecules for electron transfer and computation. Section 4 presents a brief overview of the extensive and rapidly growing field of nanomedicine. Finally, Section 5 details de-novo designed structures and the various approaches different scientific groups take with molecular level training and language

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