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Free-Radical-Induced DNA Damage and Its Repair : A Chemical Perspective
Understanding of the molecular basis of DNA damage and its repair has increased dramatically in recent years, and substantial knowledge now exists concerning the products arising from free-radical attack on DNA. Free-radical DNA damage may lead to mutations, cancer, and cell death. Free radicals have various sources, notably ionizing radiation and oxidative stress. In radiotherapy for cancer and with some anticancer drugs, use is made of cell death by excessive DNA damage. The mechanisms leading to products of free-radical attack which have been studied in models and with small double-stranded DNA fragments are discussed in detail, and the basics of the underlying free-radical chemistry are dealt with in separate chapters.
Free Energy Calculations : Theory and Applications in Chemistry and Biology
This volume sets out to present a coherent and comprehensive account of the concepts that underlie different approaches devised for the determination of free energies. The reader will gain the necessary insight into the theoretical and computational foundations of the subject and will be presented with relevant applications from molecular-level modelling and simulations of chemical and biological systems. Both formally accurate and approximate methods are covered using both classical and quantum mechanical descriptions. A central theme of the book is that the wide variety of free energy calculation techniques available today can be understood as different implementations of a few basic principles.
Frailty and Kidney Disease : A Practical Guide to Clinical Management
This book is of importance in nephrology, specifically nephrogeriatrics, since frailty is a condition affecting many elderly patients and which is becoming increasingly common in medical practice. As such, there is a considerable need for information to assist professionals treating these patients. The book includes chapters on the frailty syndrome (definition, evaluation and treatment), the main geriatric syndromes (gait disorder, falls, incontinence, and delirium), the main renal syndromes (acute renal injury, chronic kidney disease) as well as dialysis and kidney transplant, and the relationship between geriatrics and renal syndromes.
Fragility fracture nursing : Holistic care and management of the orthogeriatric patient
Aims to provide a comprehensive but practical overview of the knowledge required for the assessment and management of the older adult with or at risk of fragility fracture. It considers this from the perspectives of all of the settings in which this group of patients receive nursing care.
Fractures du genou = Knee fractures
Provides a comprehensive yet practical overview of the management of knee fractures and their complications. The editorial team comprises specialists from France, Switzerland, Belgium, the United States, and Ireland, many of whom are members of the AO group. Imaging strategies, assessment, classification, and anatomical variations are reviewed for each anatomical location. All therapeutic approaches are discussed without exception: conventional implants, intramedullary nailing, minimally invasive techniques, including the role of external fixation, and newer technologies such as the LISS. These approaches are subjected to critical analysis to identify the best options based on the indications and individual circumstances. The patellar apparatus is addressed in its functional unity. Postoperative management, influenced by functional prognosis, is also covered, as is the management of malunion, stiffness, and other complications. Finally, very specific problems are discussed, such as pediatric injuries, patellectomies, periprosthetic fractures, often complex projectile injuries, the role of immediate arthroplasty and massive grafts, but also associated injuries which sometimes have a heavy impact on the final prognosis.
Fractal Geometry, Complex Dimensions and Zeta Functions : Geometry and Spectra of Fractal Strings
Number theory, spectral geometry, and fractal geometry are interlinked in this in-depth study of the vibrations of fractal strings, that is, one-dimensional drums with fractal boundary. Key Features The Riemann hypothesis is given a natural geometric reformulation in the context of vibrating fractal strings Complex dimensions of a fractal string, defined as the poles of an associated zeta function, are studied in detail, then used to understand the oscillations intrinsic to the corresponding fractal geometries and frequency spectra Explicit formulas are extended to apply to the geometric, spectral, and dynamical zeta functions associated with a fractal Examples of such explicit formulas include a Prime Orbit Theorem with error term for self-similar flows, and a geometric tube formula The method of Diophantine approximation is used to study self-similar strings and flows Analytical and geometric methods are used to obtain new results about the vertical distribution of zeros of number-theoretic and other zeta functions Throughout new results are examined. The final chapter gives a new definition of fractality as the presence of nonreal complex dimensions with positive real parts, and discusses several open problems and extensions.
Foundations of Popfly : Rapid Mashup Development
Author Eric Griffin shows you how to mix applications and share your hybrids with the world, using the Popfly Mashup Creator and Popfly Web Page Creator.
Foundations of plasma physics for physicists and mathematicians
Foundations of Plasma Physics for Physicists and Mathematicians covers the basic physics underlying plasmas and describes the methodology and techniques used in both plasma research and other disciplines such as optics and fluid mechanics.
Foundations of Intelligent Systems ; Vol. 3488 ; 15th International Symposium ISMIS 2005, Saratoga Springs, NY, USA, May 25-28, 2005, Proceedings
This volume contains the papers selected for presentation at the 15th International S- posiumonMethodologiesforIntelligentSystems, ISMIS2005, heldinSaratogaSprings, NewYork,25-28May,2005. ThesymposiumwasorganizedbySUNYatAlbany. Itwas sponsored by the Army Research Of?ce and by several units of the University at Albany including its Division for Research, College of Arts and Sciences, Department of C- puter Science, and Institute for Informatics, Logics, and Security Studies (formerly the Institute for Programming and Logics). The Program Committee selected the following major areas for ISMIS 2005: intelligent information systems, knowledge discovery and data mining, knowledge - formation and integration, knowledge representation, logic for arti?cial intelligence, soft computing, Web intelligence, Web services, and papers dealing with applications of intelligent systems in complex/novel domains. The contributed papers were selected from almost 200 full draft papers by the Program Committee members.
Foundations of Computer Security
Foundations of Computer Security provides a succinct, yet authoritative introduction to the underlying theory, history, vocabulary, and concepts that drive this pivotal area of computer science. With its user-friendly approach and clarity of style, the text conveys—in simple terms—the core principles and developments underlying computer security in its many ramifications in the rapidly evolving computing arena. Following its opening framework laid out in a broad preface and introductory chapter, the book features chapters dedicated to a wide array of security-related subtopics: physical security, viruses and worms, malware and spyware, privacy and trust, and cryptography.
Foundation Expression Blend 2 : Building applications in WPF and silverlight
This book shows you how to take full advantage of Blend's interface, together with and Silverlight's vastly improved designer-developer workflow, guiding you through every step of development from downloading and installing of the development environment through creating finished, functional projects. You'll learn how to create simple drawing applications with the InkCanvas, make tabbed and scrollable interfaces, as well as build fully featured media players, photo galleries, and interactive 3D designs. Each chapter discusses major WPF and Silverlight features, provides a hands-on tutorial, and explains how that feature is implemented in the real world. In the end, you will have a collection of impressive WPF and Silverlight applications that can be added to your portfolio.
Foundation ASP for Dreamweaver 8
Dreamweaver 8 takes a lot of the hard work out of performing tasks such as integrating a database into your website, but it can't do everything. That's why this book not only shows you how to use all of Dreamweaver's functions, but also shows you how the underlying code functions, so you can then work around Dreamweaver's shortcomings. There's no attempt to turn you into a code guru, but you'll come away with sufficient knowledge of basic ASP to have the confidence to dive into the Dreamweaver code and tweak it to your own requirements. The emphasis is exclusively on ASP, so you don't waste any time on information that's not relevant to what you want to do.
Forming the mind : Essays on the internal senses and the Mind/Body problem from avicenna to the medical enlightenment
The book collects essays from some of the foremost scholars in a relatively new and very promising field of research. It stresses how important and fruitful it is to see the time period between 1100 and 1700 as one continuous tradition, and brings together scholars working on the same issues in the Arabic, Jewish and Western philosophical traditions. In this respect, this collection opens up several new and interesting perspectives on the history of the philosophy of mind.
Formative research in social marketing : Innovative methods to gain consumer insights
Brings together the state of the art and current debates in the field of formative research, and examines many of the innovative methods largely overlooked in the available literature. This book will help social marketing to move beyond surveys and focus groups.The book addresses the needs of social marketing academics and practitioners alike by providing a robust and critical academic discussion of cutting-edge research methods, while demonstrating at the same time how each respective method can help us arrive at a deeper understanding of the issues that social marketing interventions are seeking to remedy. Each chapter includes a scholarly discussion of key formative research methods.
Formalization of Banking Supervision : 19th–20th Centuries
Elaborate the formalization phase of banking supervision in eight developed countries—USA, Japan, Sweden, Germany, Switzerland, Belgium, France, and UK. This innovative study in the field of banking supervision history identifies why national histories of banking supervision share similarities, but also remain different and are heavily path dependent. This book will be of great interest not only to financial/economic historians but also to general readers interested in banking supervision, i.e., students, bankers, supervisors, and international officials.
Formal Techniques for Networked and Distributed Systems - FORTE 2008 ; 28th IFIP WG 6.1 International Conference Tokyo, Japan, June 10-13, 2008 Proceedings
This book constitutes the refereed proceedings of the 28th IFIP WG 6.1 International Conference on Formal Techniques for Networked and Distributed Systems, FORTE 2008, held in Tokyo, Japan, in June 2008 co-located with TestCom/FATES 2008.The 19 revised full papers and 1 revised short paper presented together with 1 invited talk were carefully reviewed and selected from 44 submissions. The papers cover new approaches, concepts and experience in the application of formal methods for the specification and verification of distributed systems and applications.
Formal techniques for networked and distributed systems - FORTE 2005 ; 25th IFIP WG 6.1 International Conference, Taipei, Taiwan, October 2-5, 2005, Proceedings
FORTE (Formal Techniques for Networked and Distributed Systems) 2005 was sp- sored by Working Group 6.1, Technical Committee 6 (TC6) of the International Fed- ation for InformationProcessing (IFIP).The conferenceseries started in 1981underthe name PSTV (ProtocolSpeci?cation, Testing, and Veri?cation).In 1988,a second series under the name FORTE was started. Both series merged to FORTE/PSTV in 1996. The conference name was changed to FORTE in 2001. During its 24-year history, many important contributions have been reported in the conference series. The last ?ve me- ings of FORTE were held in Pisa (Italy), Cheju Island (Korea), Houston (USA), Berlin (Germany), and Madrid (Spain). The 25th FORTE was held from Sunday to Wednesday, October 2–5, 2005 on the beautiful campus of the National Taiwan University (NTU), Taipei, Taiwan, ROC.
Formal Methods for Industrial Critical Systems ; 12th International Workshop, FMICS 2007, Berlin, Germany, July 1-2, 2007, Revised Selected Papers
This book constitutes the thoroughly refereed post-workshop proceedings of the 12th International Workshop on Formal Methods for Industrial Critical Systems, FMICS 2007, held in Berlin, Germany, in July 2007 - colocated with CAV 2007, the 19th International Conference on Computer Aided Verification.
Formal Methods for Components and Objects ; Vol. 4111 ; 4th International Symposium, FMCO 2005, Amsterdam, The Netherlands, November 1-4, 2005, Revised Lectures
This book presents 19 revised invited keynote lectures and revised tutorial lectures given by top-researchers at the 4th International Symposium on Formal Methods for Components and Objects, FMCO 2005, held in Amsterdam, Netherlands, in November 2005. The book provides a unique combination of ideas on software engineering and formal methods that reflect the current interest in the application or development of formal methods for large scale software systems such as component-based systems and object systems.
Formal Methods for Components and Objects ; Vol. 3657 ; 3rd International Symposium, FMCO 2004, Leiden, The Netherlands, November 2-5, 2004, Revised Lectures
This book presents revised tutorial lectures given by invited speakers at the Third International Symposium on Formal Methods for Components and Objects, FMCO 2004, held in Leiden, The Netherlands, in November 2004. The 14 revised lectures by leading researchers present a comprehensive account of the potential of formal methods applied to large and complex software systems such as component-based systems and object systems. The book provides an unique combination of ideas on software engineering and formal methods that reflect the expanding body of knowledge on modern software systems.
