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Human Drug Metabolism
The third edition of this comprehensive book covers basic concepts of teaching drug metabolism, starting from extreme clinical consequences to systems and mechanisms and toxicity. It provides an invaluable introduction to the core areas of pharmacology and examines recent progress and advances in this fast moving field and its clinical impact.
Hormonal Carcinogenesis IV
Uniquely, Hormonal Carcinogenesis IV, integrates salient aspects of hormone-related cancers of interest to epidemiologists, basic researchers, and clinicians. The most recent advances in the major hormone-related cancers are presented by leaders of their specialty. The chapters in this volume deal with the causation, dependence, and resistance of endocrine-related cancers with particular emphasis on the most common neoplasms occuring in men and woman world wide, such as breast, prostate, uterine, and ovarian cancers.
Homo Oeconomicus : The Economic Model of Behaviour and Its Applications in Economics and Other Social Sciences
The economic model of behaviour is fundamental not only in economic theory, but also in modern approaches of other social sciences, above all in political science and law. This book provides a comprehensive treatise of the general model, its philosophical and methodological foundations and its applications in different fields. In addition to the basic model, extensions to its assumptions are examined to account for complex applications like low-cost situations with moral behaviour. Finally, the book takes a broader perspective by evaluating the impact of the model on economic policy and on the development of the field of social science as a whole, such as the competition between individualistic and collectivist approaches.
HIV and AIDS : Basic elements and priorities
This volume is an excellent reference for science graduates and post graduates, medical students, research scholars and scientists across the world. This book is recommended by the World Health Organization Eastern Mediterranean Region Office (WHO-EMRO) as a basic resource for medical faculty libraries.
H-infinity control and estimation of state-multiplicative linear systems
This monograph embodies a comprehensive survey of the relevant literature with basic problems being formulated and solved by applying various techniques including game theory, linear matrix inequalities and Lyapunov parameter-dependent functions.
Hilbert-Huang Transform Analysis Of Hydrological And Environmental Time Series
The Hilbert-Huang Transform ((HHT) is a recently developed technique which is used to analyze nonstationary data. Hydrologic and environmental series are, in the main, analyzed by using techniques which were developed for stationary data. This has led to problems of interpretation of the results. Environmental and hydrologic series are quite often nonstationary. The basic objective of the material discussed in this book is to analyze these data by using methods based on the Hilbert-Huang transform. These results are compared to the results from the traditional methods such as those based on Fourier transform and other classical statistical tests.
Highway engineering : Planning, design, and operations ; 2nd ed.
Presents a clear and rigorous exposition of highway engineering concepts, including project development and the relationship between planning, operations, safety and highway types. The book includes important topics such as corridor selection and traverses, horizontal and vertical alignment, design controls, basic roadway design, cross section elements, intersection and interchange design, and the integration of new vehicle technologies and trends. It also presents end of chapter exercises to further aid understanding and learning. This edition has been fully updated with the current design policies and reference manuals essential for highway, transportation, and civil engineers who are required to work to these standards.
High-Resolution Methods for Incompressible and Low-Speed Flows
This book covers the basic techniques for simulating incompressible and low-speed flows with high fidelity in conjunction with high-resolution methods. This includes techniques for steady and unsteady flows with high-order time integration and multigrid methods.
Highly Sensitive Optical Receivers
Highly Sensitive Optical Receivers primarily treats the circuit design of optical receivers with external photodiodes. Continuous-mode and burst-mode receivers are compared. The monograph first summarizes the basics of III/V photodetectors, transistor and noise models, bit-error rate, sensitivity and analog circuit design, thus enabling readers to understand the circuits described in the main part of the book. In order to cover the topic comprehensively, detailed descriptions of receivers for optical data communication in general and, in particular, optical burst-mode receivers in deep-sub-µm CMOS are presented. Numerous detailed and elaborate illustrations facilitate better understanding.
High-Energy Spectroscopic Astrophysics : Saas Fee Advanced Course 30. Lecture Notes 2000. Swiss Society for Astrophysics and Astronomy
After three decades of intense research in X-ray and gamma-ray astronomy, the time was ripe to summarize basic knowledge on X-ray and gamma-ray spectroscopy for interested students and researchers ready to become involved in new high-energy missions. This volume exposes both the scientific basics and modern methods of high-energy spectroscopic astrophysics. The emphasis is on physical principles and observing methods rather than a discussion of particular classes of high-energy objects, but many examples and new results are included in the three chapters as well.
High Thermal Conductivity Materials
High thermal conductivity materials play an important role in addressing thermal management issues. This volume provides readers a basic understanding of the thermal conduction mechanisms in these materials and discusses how the thermal conductivity may be related to their crystal structures as well as microstructures developed as a result of their processing history. The techniques for accurate measurement of these properties on large as well as small scales have been reviewed. Detailed information on the thermal conductivity of diverse materials including aluminum nitride (AlN), silicon carbide (SiC), diamond, as well as carbon nanotubes has been presented. The emphasis is on developing basic understanding of the inter-relationships between thermal conductivity and processing such that the readers can conduct their own research in this exciting field of high thermal conductivity materials.
High Power Diode Lasers : Technology and Applications
In a very comprehensive way this book covers all aspects of high power diode laser technology for materials processing. Basics as well as new application oriented results obtained in a government funded national German research project are described in detail.
High performance computing in science and engineering, Garching 2004 ; Transaction of the KONWIHR Result Workshop, October 14-15, 2004, Technical University of Munich, Garching, Germany
This volume of High Performance Computing in Science and Engineering is fully dedicated to the final report of KONWIHR, the Bavarian Competence Network for Technical and Scientific High Performance Computing. It covers projects from basic research in computer science to develop tools for high performance computing as well as applications from biology, chemistry, electrical engineering, geology, mathematics, physics, computational fluid dynamics, materials science and computer science.
High Energy Polarized Proton Beams : A Modern View
This monograph begins with a review of the basic equations of spin motion in particle accelerators. It then reviews how polarized protons can be accelerated to several tens of GeV using as examples the preaccelerators of HERA, a 6.3 km long cyclic accelerator at DESY / Hamburg. Such techniques have already been used at the AGS of BNL / New York, to accelerate polarized protons to 25 GeV. But for acceleration to energies of several hundred GeV as in RHIC, TEVATRON, HERA, LHC, or a VLHC, new problems can occur which can lead to a significantly diminished beam polarization. For these high energies, it is necessary to look in more detail at the spin motion, and for that the invariant spin field has proved to be a useful tool. This is already widely used for the description of high-energy electron beams that become polarized by the emission of spin-flip synchrotron radiation. It is shown that this field gives rise to an adiabatic invariant of spin-orbit motion and that it defines the maximum time average polarization available to a particle physics experiment.
High dilution effects : Physical and biochemical basis
this volume provides evidence in support of effects from control clinical studies, and in vitro tests without any organisms (Chapter II). An overview of the methods for preparing drugs at ultra high dilution is also provided as well as the basic principles of homeopathy, (Chapter I). Chapter III provides physical basis of high dilutions as evidence from the NMR, IR, UV and fluorescence spectra of those drugs.Chapter IV focuses on the mechanism of action of potentized drugs in the living system, discussing the structure of the cell, the plasma membrane, the integral proteins on the membrane, the interaction between these proteins and high dilutions and the manifestations of the therapeutic effects of high dilutions.
Hexagonal image processing : A practical approach
Hexagonal Image Processing provides an introduction to the processing of hexagonally sampled images, includes a survey of the work done in the field, and presents a novel framework for hexagonal image processing (HIP) based on hierarchical aggregates. Digital image processing is currently dominated by the use of square sampling lattices, however, hexagonal sampling lattices can also be used to define digital images. The strengths offered by hexagonal lattices over square lattices are considerable: • higher packing density, • uniform connectivity of points (pixels) in the lattice, • better angular resolution by virtue of having more nearest neighbours, and • superlative representation of curves. The utility of the HIP framework is demonstrated by implementing several basic image processing techniques (for the spatial and frequency domain) and some applications. The HIP framework serves as a tool for comparing processing of images defined on a square vs hexagonal grid, to determine their relative merits and demerits. The theory and algorithms covered are supplemented by attention to practical details such as accommodating hardware that support only images sampled on a square lattice. Including a Foreword written by Professor Narendra Ahuja, an eminent researcher in the field of Image Processing and Computer Vision, the book’s fresh approach to the subject offers insight and workable know-how to both researchers and postgraduates.
Hepatitis C Virus Disease
Emphasizes the most recent advances on the Hepatitis C virus infection (HCV) moving from basic research to clinical application. In spite of the numerous studies on HCV infection, its pathogenesis and medical treatment have not been fully explained. The first chapters of this volume analyize the full spectrum of immune responses to HCV taking into account either innate or adoptive immunity involvement. The volume also includes a series of contributions which explain the state of art of IFN-alpha treatment in HCV patients and the effectiveness of therapy also in relation to HCV genotypes. The use and applications of pegylated IFNs will also be discussed as well as the complicated HCV disease and its treatment. Hepatitis C Virus Disease: Immunobiology and Clinical Applications is an ideal volume for researchers, scientists, professionals, clinicians, physicians and graduate students in the fields of infectious disease, immunology, virology, microbiology, pharmacology and medicine.
Hedgehog-Gli Signaling in Human Disease
Hedgehog-GLI Signaling in Human Disease represents the first compilation of up-to-date reviews by top-level scientists in this important field of research. The chapters cover a wide spectrum of related interests, from the molecular bases of morphogen function, to human genetics to cancer research. The aim of the book is to disseminate information on this exciting field, to allow students, scientists and the public in general to gain access current information from research leaders and to provide a book that encompasses different aspects of research showing the fusion of basic research in model systems and medicine. This is a timely primer on how a system of cell communication, Hedgehog-GLI signaling, plays a critical role in human disease and thus provides the background for the development of novel and rational therapies.
Heating, cooling, lighting : Sustainable design methods for architects
Helps architects minimize mechanical systems and energy usage over the life of the building by siting, building design, and landscaping to maximize natural heating, cooling, and lighting. This new fourth edition includes new information on integrated design strategies and designing for the Tropics. Resources include helpful case studies, checklists, diagrams, and a companion website featuring additional cases, an image bank, and instructor materials. Designing buildings that require less energy to heat, cool, and light means allowing the natural energy of the sun and wind to reduce the burden on the mechanical and electrical systems. Basic design decisions regarding size, orientation, and form have a great impact on the sustainability, cost, and comfort of a building. Heating, Cooling, and Lighting provides detailed guidance for each phase of a design project.
Heat and Mass Transfer
This comprehensive textbook provides readers with a firm foundation in the principles of heat and mass transfer and shows them how to solve problems by applying modern methods. The basic theory is developed systematically, and the solution methods to all important problems are covered in detail. The second edition incorporates state-of-the-art findings on heat and mass transfer correlations. Therefore, this book will be useful not only to upper- and graduate-level students, but also to practicing scientists and engineers. Many worked-out examples and numerous exercises with their solutions will facilitate learning and understanding, and an appendix includes data on key properties of important substances.
