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Flow and microreactor technology in medicinal chemistry

The ultimate dream for medicinal chemists is the ability to synthesize new drug-like compounds with the push of a button. The key to synthesizing chemical compounds more quickly and accurately lies in computer-controlled technologies that can be optimized by machine learning. Recent developments in computer-controlled automated syntheses that rely on miniature flow reactors—with integrated analysis of the resulting products—provide a workable technology for synthesizing new chemical substances very quickly and with minimal effort.

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Flood Risk Management : Hazards, Vulnerability and Mitigation Measures

Floods are of increasing public concern world-wide due to increasing damages and unacceptably high numbers of injuries. Previous approaches of flood protection led to limited success especially during recent extreme events. Therefore, an integrated flood risk management is required which takes into consideration both the hydrometeorogical and the societal processes. Moreover, real effects of risk mitigation measures have to be critically assessed. The book draws a comprehensive picture of all these aspects and their interrelations. It furthermore provides a lot of detail on earth observation, flood hazard modelling, climate change, flood forecasting, modelling vulnerability, mitigation measures and the various dimensions of management strategies. In addition to local and regional results of science, engineering and social science investigations on modelling and management, transboundary co-operation of large river catchments are of interest.

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FinFETs and Other Multi-Gate Transistors

FinFETs and Other Multi-Gate Transistors provides a comprehensive description of the physics, technology and circuit applications of multigate field-effect transistors (FETs). It explains the physics and properties of these devices, how they are fabricated and how circuit designers can use them to improve the performances of integrated circuits.

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Fine- and Coarse-Grain Reconfigurable Computing

The FPGA technology is defined, which includes architecture, logic block structure, interconnect, and configuration methods and existing fine-grain reconfigurable architectures emerged from both academia and industry. Additionally, the implementation techniques and CAD tools developed to facilitate the implementation of a system in reconfigurable hardware by the industry and academia are provided.

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Field Manual of Techniques in Invertebrate Pathology : Application and Evaluation of Pathogens for Control of Insects and other Invertebrate Pests

The Field Manual of Techniques in Invertebrate Pathology is designed to provide background and instruction on a broad spectrum of techniques and their use in the evaluation of entomopathogens in the field. The second edition of the Field Manual provides updated information and includes two additional chapters and 12 new contributors. The intended audience includes researchers, graduate students, practitioners of integrated pest management (IPM), regulators and those conducting environmental impact studies of entomopathogens. Although it can function as a stand alone reference, the Field Manual is complementary to the laboratory oriented Manual of Techniques in Insect Pathology and to comprehensive texts in insect pathology.

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Feedforward Amplifiers for Wideband Communication Systems

Feedforward Amplifiers for Wideband Communication Systems has been possible thanks to the research carried out throughout several years in the field of the linearization techniques applied to digital communication systems, particularly to those with high spectral efficient modulation techniques. This challenge is enshrined in one of the present wideband communication systems, but all the recommended design guidelines are perfectly reusable in the future wideband applications.

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Fault-Tolerance Techniques for SRAM-Based FPGAs

This book discusses fault-tolerance techniques for SRAM-based Field Programmable Gate Arrays (FPGAs). It starts by showing the model of the problem and the upset effects in the programmable architecture. In the sequence, it shows the main fault tolerance techniques used nowadays to protect integrated circuits against errors. A large set of methods for designing fault tolerance systems in SRAM-based FPGAs is described. Some presented techniques are based on developing a new fault-tolerant architecture with new robustness FPGA elements. Other techniques are based on protecting the high-level hardware description before the synthesis in the FPGA.

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Fault Diagnosis of Analog Integrated Circuits

Fault Diagnosis of Analog Integrated Circuits is a textbook for advanced undergraduate and graduate level students as well as practicing engineers. The objective of this book is to study the testing and fault diagnosis of analog and analog part of mixed signal circuits. A background in analog integrated circuit, artificial neural network is desirable but not essential.

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Experimental Aspects of Quantum Computing

Practical quantum computing still seems more than a decade away, and researchers have not even identified what the best physical implementation of a quantum bit will be. There is a real need in the scientific literature for a dialog on the topic of lessons learned and looming roadblocks. These papers, which appeared in the journal of "Quantum Information Processing" are dedicated to the experimental aspects of quantum computing These papers highlight the lessons learned over the last ten years, outline the challenges over the next ten years, and discuss the most promising physical implementations of quantum computing.

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Existence and Regularity Properties of the Integrated Density of States of Random Schrödinger Operators

The theory of random Schrödinger operators is devoted to the mathematical analysis of quantum mechanical Hamiltonians modeling disordered solids. Apart from its importance in physics, it is a multifaceted subject in its own right, drawing on ideas and methods from various mathematical disciplines like functional analysis, selfadjoint operators, PDE, stochastic processes and multiscale methods. The present text describes in detail a quantity encoding spectral features of random operators: the integrated density of states or spectral distribution function. Various approaches to the construction of the integrated density of states and the proof of its regularity properties are presented.

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Evidence-based decision making in dentistry : Multidisciplinary management of the natural dentition

Covers all aspects of the evidence-based decision making process in multidisciplinary management of the natural dentition. Individual chapters focus specifically, and in detail, on endodontic, periodontal, and prosthetic considerations, identifying aspects that need to be integrated into decision making and treatment planning. Evidence-based decision making with regard to preservation of the natural tooth versus extraction and implant placement is then discussed, and a concluding chapter examines likely future trends in dentistry and how they may affect clinical decision making.

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Event-Triggered and Time-Triggered Control Paradigms

Event-Triggered and Time-Triggered Control Paradigms presents a valuable survey about existing architectures for safety-critical applications and discusses the issues that must be considered when moving from a federated to an integrated architecture. The book focuses on one key topic--the amalgamation of the event-triggered and the time-triggered control paradigm into a coherent integrated architecture. The architecture provides for the integration of independent distributed application subsystems by introducing multi-criticality nodes and virtual networks of known temporal properties.

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Evaluation of text summaries based on linear optimization of content metrics

Covers both theoretical contributions and practical applications in security system design by applying the Internet of Things (IoT) and CI. It further explains the application of IoT in the design of modern security systems and how IoT blended with computational intel- ligence can make any security system improved and realizable. Key features: Focuses on the computational intelligence techniques of security system design Covers applications and algorithms of discussed computational intelligence techniques Includes convergence-based and enterprise integrated security systems with their applications Explains emerging laws, policies, and tools affecting the landscape of cyber security Discusses application of sensors toward the design of security systems This book will be useful for graduate students and researchers in electrical, computer engineering, security system design and engineering

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Esthetic and functional management of Diastema : A multidisciplinary approach

Offers detailed guidance on integrated orthodontic, periodontal, and restorative solutions for the treatment of diastema, highlighting the advantages of such a multidisciplinary approach and presenting suitable clinical protocols for esthetic reconstruction and functional improvement.

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Essentials of human disease in dentistry

Takes an integrated approach to dentistry and how it relates to general medicine, surgery, pharmacology, therapeutics, pathology and microbiology.

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Essentials of Computer Organization and Architecture

Addresses all necessary organization and architecture topics, but concise enough to be appropriate for a single-term course. Its focus on real-world examples and practical applications encourages students to develop a “big-picture” understanding of how essential organization and architecture concepts are applied in the computing world. In addition to direct correlation with the ACM/IEEE guidelines for computer organization and architecture, the text exposes readers to the inner workings of a modern digital computer through an integrated presentation of fundamental concepts and principles.

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Essential Issues in SOC Design : Designing Complex Systems-on-Chip

SOC design is fast becoming the key area of focus that engineers and researchers from the Electronic Design Automation field are focusing on in their quest to further develop Integrated Circuit technology. The more systems and even networks that we can integrate on one piece of silicon, the faster, cheaper, more powerful and efficient the technology will become. Essential Issues in SOC Design contains valuable academic and industrial examples for those involved with the design of complex SOCs, all contributors are selected from a region of the world that is generally known to lead the "SOC-Revolution", namely Asia.

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ESD Protection Device and Circuit Design for Advanced CMOS Technologies

ESD Protection Device and Circuit Design for Advanced CMOS Technologies is intended for practicing engineers working in the areas of circuit design, VLSI reliability and testing domains.

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Environmentally-Friendly Product Development: Methods and Tools

Presents a survey of eco-friendly product design. This work is aimed at researchers and academics in design engineering and practitioners and managers in the industry

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Environmental History of the Rhine-Meuse Delta : An ecological story on evolving human–environmental relations coping with climate change and sea-level rise

This book presents the environmental history of the Delta of the lowland rivers Rhine and Meuse, an ecological story on evolving human–environmental relations coping with climate change and sea-level rise. It offers a combination of in-depth ecology and environmental history, dealing with exploitation of land and water, the use of everything nature provided, the development of fisheries and agriculture, changes in biodiversity of higher plants, fish, birds, mammals and invasive exotics. It is the first comprehensive book written in English on the integrated environmental history of the Delta, from prehistoric times up to the present day. It covers the l- acy of human intervention, the inescapable fate of reclaimed, nevertheless subs- ing and sinking polders, ‘bathtubs’ attacked by numerous floods, reclaimed in the Middle Ages and unwittingly exposed to the rising sea level and the increasing amplitude between high and low water in the rivers. The river channels, constricted and regulated between embankments, lost their flood plains, silted up, degraded and incised. Cultivation of raised bog deposits led to oxidation and compacting of peat and clay, resulting in progressive subsidence and flooding; arable land had to be changed into grassland and wetland. For millennia muscular strength and wind and water powers moulded the country into its basic form. From 1800 onwards, acceleration and scaling up by steam power and electricity, and exponential popu- tion growth, resulted in the erection of human structures ‘fixed forever’, and severe pressure on the environment.

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