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Lung Pathology

Learning the diagnostic elements of lung pathology requires not only great familiarity with a wide diversity of cases, but also a sharp eye for analyzing pictorial images. In Lung Pathology: A Consultative Atlas, leading experts offer a novel and substantive approach to the teaching of pulmonary pathology. Drawing on 263 challenging, yet exemplary, referral cases taken from files collected over 20 years by internationally renowned lung pathologist, Dr. Eugene Mark, the authors introduce his state-of-the-art approach to the interpretation of pulmonary pathology. This text includes the primary and/or differential diagnosis and the pertinent histological features of each case, as well as clinical history, when available. Key words or phrases in the text are highlighted and digitally hyperlinked to associated images or regions of interest within those images to assist the readers in their correlation. Novel and user friendly, Lung Pathology: A Consultative Atlas describes a cutting-edge diagnostic approach to pulmonary pathology, describing its principles and demonstrating its application in text and full-color illustrations drawn from 263 difficult cases of human lung pathologies.

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Clinical Neuro-Ophthalmology : A Practical Guide

Clinical Neuro-Ophthalmology is a challenge for residents and experienced clinicians alike. This book covers all relevant techniques of diagnosis as well as interpretations of clinical signs. All information is highly structured, highlighting ‘definition’, ‘note’ and ‘pearl’, so that it can also be used by the physician during the patient encounter. The included flow chart posters remind the physician of the most important information.

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Clinical Cardiac MRI

MRI has become the preferred noninvasive imaging modality for the heart and great vessels. The substantial technological progress achieved in recent years has provided the user with state of the art MRI systems, but their optimal use can be limited by restricted awareness of the potential patient benefit and the necessity for teaching. This extensively illustrated volume, has been specifically compiled to meet these needs. Essential theoretical background information is provided, and imaging acquisition and potential pitfalls are considered in detail. Most importantly, structured guidelines are provided on the interpretation of clinical data in the wide range of cardiac pathology that can be encountered. Throughout, the emphasis is on the implementation of cardiac MRI in clinical practice.

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Chemical Leasing Goes Global : Selling Services Instead of Barrels : A Win-Win Business Model for Environment and Industry

Chemical Leasing is an innovative business model within the sustainable management of chemicals. The economic benefit is achieved by selling chemicals services instead of increasing the sales volume. This book contains detailed descriptions and evaluations based on existing projects in Austria, Egypt, Russia and Mexico where in a broard range of sectors and companies the application of Chemical leasing was assisted. The book also contains political and scientific interpretations and analyses.

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Cardiovascular MRI in practice : A teaching file approach

This text resource outlines the systematic approach to CMR interpretation. The depiction of a "core exam" and the modifications used for a variety of patient circumstances are demonstrated using simple visual assessment of the images. Special emphasis on the advantages of CMR relative to other modalities reinforces practical learning objectives, organized so that the reader starts with patient images – as one would in a clinical scenario – and works back to the didactic material.

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Cancer Informatics in the Post Genomic Era : Toward Information-Based Medicine

Medical information science requires analytic tools. This is achieved by developing and assessing methods and systems for the acquisition, processing, and interpretation of patient data, aided by scientific discovery. Cancer Informatics in Post-Genomic Era provides both the necessary methodology and practical information tools.Key challenges include integrating research and clinical care, sharing data, and establishing partnerships within and across sectors of patient diagnosis and treatment.Addressing important clinical questions in cancer research will benefit from expanding computational biology.

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Blood traces : Interpretation of deposition and distribution

Blood Traces provides an authoritative resource that reviews many of the aspects of the interpretation of blood traces that have not been treated with the thoroughness they deserve. With strict adherence to the scientific method, the authors — noted experts on the topic — address the complexities encountered when interpreting blood trace configurations. The book provides an understanding of the scientific basis for the use of blood trace deposits, i.e. bloodstain patterns, at crime scenes to better reconstruct a criminal event.

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Bioinformatics drug discovery

Quantitative tools are becoming increasingly important in order to understand complex cascade of signal transduction events, pathways or biochemical reactions. The book showcases how computational techniques and algorithms are applied to biological data analysis, interpretation, and modelling. It covers applications in drug design and discovery, immune systems, phylogenetic analysis and protein structures.

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Basic & Clinical Biostatistics

Provides medical students, researchers, and practitioners with the knowledge needed to develop sound judgment about data applicable to clinical care. This fifth edition has been updated throughout to deliver a comprehensive, timely introduction to biostatistics and epidemiology as applied to medicine, clinical practice, and research. Particular emphasis is on study design and interpretation of results of research.

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Analytical Techniques in Forensic Science

Analytical Techniques in Forensic Science is a comprehensive guide written in accessible terms that examines the interface between analytical chemistry and trace evidence in forensic science. With contributions from noted experts on the topic, the text features a detailed introduction analysis in forensic science and then subsequent chapters explore the laboratory techniques grouped by shared operating principles. For each technique, the authors incorporate specific theory, application to forensic analytics, interpretation, forensic specific developments, and illustrative case studies.

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Analysis file of drug-induced lung injury : expert opinion for analysis of big data

Describes the pathologic conditions of drug-induced lung injuries, monitoring strategies, and guides on how to interpret the evidence. It also dives into particular drugs that caused the disorder, such as EGFR inhibitors, anti-EGFR antibodies, mTOR inhibitors, proteasome inhibitors, immune checkpoint inhibitors, neoangiogenesis inhibitors, and other molecular targeted drugs. It outlines the analysis and interpretation of the post-marketing survey on surveillance of each drug for inducing pulmonary lesions presenting diffuse haziness. The data and analysis from this survey are valuable since a guideline is yet to be established due to limited clinical evidence and cases. As new drugs are developed, establishing treatment and event management is crucial.

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A History of Limb Amputation

This book traces humanity’s long experience of natural amputations due to congenital absence, disease, frostbite, toxins, domestic and wild animal trauma, and for non-medical reasons related to punitive, ritual, and legal actions, ultimately leading to the development of elective surgical amputation. While the evolution of surgical techniques forms a major chapter in the book, many ancillary problems are addressed including the control of hemorrhage and infection, the approach to pain relief, the development of suitable instruments and equipment, and the invention of prostheses, all suitably illuminated with case histories and relevant illustrations. In addition, alternative procedures designed to avoid amputation, increasingly important in the last two centuries, are debated, and factors associated with self-amputation in extremis, not rare according to press reports, are also examined. A separate chapter considers the philosophy and interpretations of society, patients, and surgeons faced with amputation, particularly before anesthesia.

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Judges and Adjudication in Constitutional Democracies : A View from Legal Realism

Offers contributions to a philosophical and realistic approach to the place of adjudication in contemporary constitutional democracies. Bringing together scholars from different legal and philosophical backgrounds, purports to cast light on the role(s) of judges and the function of judicial interpretation inside of constitutional states, from the standpoint of legal realism as a revisited and sophisticated jurisprudential outlook. In so doing, also copes with a few major jurisprudential issues, like, e.g., determining the ideas that make up the core of legal realism, exploring the relation between legal realism and legal positivism, identifying the boundaries of judicial interpretation as they appear from a realist standpoint, as well as considering some skeptical outlooks on the very claims of contemporary legal realism.​

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Algorithms in Bioinformatics : Theory and Implementation

Explores a comprehensive and insightful treatment of the practical application of bioinformatic algorithms in a variety of fields. Delivers a fulsome treatment of some of the main algorithms used to explain biological functions and relationships. It introduces readers to the art of algorithms in a practical manner which is linked with biological theory and interpretation. The book covers many key areas of bioinformatics, including global and local sequence alignment, forced alignment, detection of motifs, Sequence logos, Markov chains or information entropy. Other novel approaches are also described, such as Self-Sequence alignment, Objective Digital Stains (ODSs) or Spectral Forecast and the Discrete Probability Detector (DPD) algorithm. Readers will also benefit from the inclusion of: A detailed presentation of new methods, such as Self-sequence alignment, Objective Digital Stains and Spectral Forecast ; A treatment of sequence alignment, including local sequence alignment, global sequence alignment and forced sequence alignment with full implementations ; Discussions of position-specific weight matrices, including the count, weight, relative frequencies, and log-likelihoods matrices ; A detailed presentation of the methods related to Markov Chains as well as a description of their implementation in Bioinformatics and adjacent fields ; An examination of information and entropy, including sequence logos and explanations related to their meaning ; A chapter on philosophical transactions that allows the reader a broader view of the prediction process ; Extensive worked examples with detailed case studies that point out the meaning of different results

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Advances and applications of DSmT for information fusion: Collected works ; Vol.3

One of the most comprehensive and flexible fusion theory based on belief functions. It can work in all fusion spaces: power set, hyper-power set, and super-power set, and has various fusion and conditioning rules that can be applied depending on each application. Some new generalized rules are introduced in this volume with codes for implementing some of them. For the qualitative fusion, the DSm Field and Linear Algebra of Refined Labels (FLARL) is proposed which can convert any numerical fusion rule to a qualitative fusion rule. When one needs to work on a refined frame of discernment, the refinement is done using Smarandache s algebraic codification. New interpretations and implementations of the fusion rules based on sampling techniques and referee functions are proposed, including the probabilistic proportional conflict redistribution rule.

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Advances and applications of DSmT for information fusion ; Vol. 4

One of the most comprehensive and flexible fusion theory based on belief functions. It can work in all fusion spaces: power set, hyper-power set, and super-power set, and has various fusion and conditioning rules that can be applied depending on each application. Some new generalized rules are introduced in this volume with codes for implementing some of them. For the qualitative fusion, the DSm Field and Linear Algebra of Refined Labels (FLARL) is proposed which can convert any numerical fusion rule to a qualitative fusion rule. When one needs to work on a refined frame of discernment, the refinement is done using Smarandache s algebraic codification. New interpretations and implementations of the fusion rules based on sampling techniques and referee functions are proposed, including the probabilistic proportional conflict redistribution rule.

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Abstract Computing Machines : A Lambda Calculus Perspective

The book addresses ways and means of organizing computations, highlighting the relationship between algorithms and the basic mechanisms and runtime structures necessary to execute them using machines. It completely abstracts from concrete programming languages and machine architectures, taking instead the lambda calculus as the basic programming and program execution model to design various abstract machines for its correct implementation. The emphasis is on fully normalizing machines based on full-fledged beta-reductions as essential prerequisites for symbolic computations that treat functions and variables truly as first-class objects. Their weakly normalizing counterparts are shown to be functional abstract machines that sacrifice the flavors of full beta-reductions for decidedly simpler runtime structures and improved runtime efficiency. Further downgrading of the lambda calculus leads to classical imperative machines that permit side-effecting operations on the runtime environment.

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A Computational Model of Natural Language Communication : Interpretation, Inference, and Production in Database Semantics

Part I of this book presents a high-level description of an artificial agent which humans can freely communicate with in their accustomed language. Part II analyzes the major constructions of natural language, i.e., intra- and extrapropositional functor - argument structure, coordination, and coreference, in the speaker and the hearer mode. Part III defines declarative specifications for fragments of English, which are used for an implementation in Java.

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25 Years of Model Checking : History, Achievements, Perspectives

Model checking technology is among the foremost applications of logic to computer science and computer engineering. The model checking community has achieved many breakthroughs, bridging the gap between theoretical computer science and hardware and software engineering, and it is reaching out to new challenging areas such as system biology and hybrid systems. Model checking is extensively used in the hardware industry and has also been applied to the verification of many types of software. Model checking has been introduced into computer science and electrical engineering curricula at universities worldwide and has become a universal tool for the analysis of systems.

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Burnt human remains : Recovery, analysis, and interpretation

Presents an in-depth multidisciplinary approach to the detection, recovery, analysis, and identification of thermally altered remains. Bridging the gap between research and practice, this invaluable one-stop reference provides detailed coverage of analytical techniques in forensic medicine and pathology, forensic anthropology, forensic odontology, and forensic chemistry and forensic biology.

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