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NEURO-COVID-19 : Neuroinvasive potential and neurological complications of SARS-CoV-2

From the earliest days of the COVID-19 pandemic, there have been reports of significant neurological and psychological symptoms following SARS-CoV-2 infection. This research paper is designed to examine the potential psychoneuroendocrine pathogenic mechanisms by which SARS-CoV-2 elicits psychiatric sequelae, as well as to posit potential pharmacologic strategies to address and reverse these pathologies. Following a brief overview of the presence and prevalence of neuropsychiatric manifestation in COVID-19 patients, we address mechanisms by which SARS-CoV-2 could enter or otherwise elicit changes in the CNS.

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Misinterpretations about Covid-19 vaccines

Immunization has become a vital part of public health and disease prevention, yet remain Vaccination is the most effective medical intervention ever a controversial topic. introduced, it has eliminated a large part of the infectious diseases that once killed millions of people. Recently, a number of effective vaccines have been manufactured and proved to be effective against the virus, but a rising incidents was observed of refusing people to take COVID-19 (SARS-CoV-2) vaccine because of the wrong myths they hear about the vaccine or its existing and non-existing side effects. The purpose of this research is to clarify information and remove vagueness about the vaccines and definitively convert fake concepts into facts by answering questions in a scientific method.

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Medical data processing and analysis

Medical data can be defined as obtaining information from patients (such as signals, images, sounds, chemical components and their concentration, body temperature, respiratory rate, blood pressure, and different treatment measurements) to quantify the patient’s status and disease stage. Computer-aided diagnostic (CAD) systems use classical image processing, computer vision, machine learning, and deep learning methods for image analysis. Using image classification or segmentation algorithms, they find a region of interest (ROI) pointing to a specific location within the given image or an outcome of interest in the form of a label pointing to a diagnosis or prognosis. Computer science, with the evolution of artificial intelligence and machine learning techniques, facilitates the modeling and interpretation of results—from carrying out measurements to experiments and observations.

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Inflammation and cancer : Methods and protocols

Discusses the latest findings on the development and characterization of representative research models for chronic immune-based diseases and inflammation-associated cancers.And covers biochemical, molecular, and cellular biological techniques that are commonly used to dissect the molecular mechanisms and cellular processes that drive the pathogenesis of certain disease states.

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How Apollo flew to the moon

Out of the technological battlefield of World War II came a team of gifted German engineers and designers who developed the vengeance weapon, the V-2, which evolved into the peaceful, powerful Saturn V rocket to take men to the Moon. David Woods tells the exciting story, starting from America’s post war astronautical research facilities, that used the V-2 for the development of the robust, resilient and reliable Saturn V launcher. He describes the initial launches through manned orbital spaceflights, comprehensively detailing each step, including computer configuration, the role of ground control, trajectory planning, lunar orbiting, separation of the lander, walking and working on the Moon, retrieval of the lunar astronauts and returning to Earth in this massive technical accomplishment.

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Herbal immunity boosters against COVID-19

Provides an introduction to COVID-19 and herbal medications that boost the human immune system against SARS-CoV-2. The topics are covered in 7 chapters starting with an introduction to the disease, followed by notes on nutraceuticals and common herbal medicines that have therapeutic potential by enhancing the patient’s immune response. Special topics such as COVID-19 risk factors and Indian traditional medicines are also included to supplement the contents. The editors have taken advantage of the vast body of knowledge accumulated since the start of the COVID-19 pandemic in 2019.

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Differential Equations Driven by Rough Paths : Ecole d’Eté de Probabilités de Saint-Flour XXXIV-2004

The goal of these notes is to provide a straightforward and self supporting but minimalist account of the key results forming the foundation of the theory of rough paths.

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Detection and analysis of SARS Coronavirus : Advanced biosensors for pandemic viruses and related pathogens

The highly contagious SARS CoV-2 pathogen has challenged health systems around the world as they struggle to detect and monitor the spread of the pathogen. In Detection and Analysis of SARS Coronavirus: Advanced Biosensors for Pandemic Viruses and Related Pathogens expert chemists Chaudhery Mustansar Hussain and Sudheesh K. Shukla deliver a practical analysis of how contactless coronavirus detectors may be developed using existing biosensor technology.

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Dental care and oral health during the COVID-19 pandemic

Disseminates relevant knowledge of the recent SARS-Cov-2 pandemic with a focus on related applications in the fields of medicine and dentistry. Different types of manuscripts concerning these topics will be considered, including clinical studies, trials, systematic reviews, prospective studies, and proposals of new protocols or scientific evidence regarding dental clinics and SARS-Cov-2 infections.

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COVID-19: Diagnosis and Treatment

The global coronavirus disease 2019 (COVID- 19) has presented major challenges for clinical laboratories, from initial diagnosis to patient monitoring and treatment. Initial response to this pandemic involved the development, production, and distribution of diagnostic molecular assays at an unprecedented rate, leading to minimal validation requirements and concerns regarding their diagnostic accuracy in clinical settings. In addition to molecular testing, serological assays to detect antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are now becoming available from numerous diagnostic manufacturers. In both cases, the lack of peer-reviewed data and regulatory oversight, combined with general misconceptions regarding their appropriate use, have highlighted the importance of laboratory professionals in robustly validating and evaluating these assays for appropriate clinical use.

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COVID-19 in dentistry and dental education

Dentistry has already been shown to be a hazardous occupation due to the numerous infectious and health risks associated with it. Over the past year and a half, this risk has only grown because of the highly transmissible nature of the Coronavirus. Dentistry, being a profession where the operator and the assistants are in close contact with the patients, has seen numerous changes. Not only this, but even dental education has been impacted as most of the teaching over the pandemic period has been conducted online. Furthermore, dental education has been highly impacted as a major part of it involves hands-on training. Due to this, there are several social, financial, and health-related repercussions that must be analyzed and understood. This Special Issue invited manuscripts, both research and review, that analyze the SARS-CoV-2 situation with regard to dentistry and dental education.

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COVID-19 in Alzheimer's disease and dementia

COVID-19 in Alzheimer’s Disease and Dementia crucially summarizes the current status of the coronavirus in patients suffering from these conditions, describing why they are a common cause of morbidity among those with COVID-19. The first section includes chapters that provide a general description of COVID-19, including SARS-CoV-2 structure, function, and biology, and its impact on the elderly with chronic conditions include hypertension, diabetes, obesity, kidney disease, respiratory illnesses, and infectious diseases. Also discussed are effects of the virus on the immune system. The second section shifts to the impact of COVID-19 on those with dementia or Alzheimer’s disease, with special emphasis on age, gender, ethnic background, and lifestyle.

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COVID-19 & Cardiovascular Complications

A highly pathogenic human coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been recently recognized in Wuhan, China, as the cause of the coronavirus disease 2019 (COVID-19) outbreak which has spread rapidly from China to other countries in the world, causing a pandemic with alarming morbidity and mortality. The emerging epidemiological data about COVID-19 patients suggest an association between cardiovascular diseases (CVD) and SARS-CoV-2 infection, in term of clinical features at hospital admission and prognosis for disease severity. The aim of our review is to describe the cardiological features of COVID-19 patients at admission, the acute cardiac presentation, the clinical outcome for patients with underlying CVD and the pharmacological implications for disease management.

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Coronavirus therapeutics ; Vol. II : Clinical management and public health

Provides the most comprehensive review on contemporary knowledge on the consequences during the outbreak of Coronavirus. This also describes the clinical features, diagnostic evaluation and management of Coronavirus patients. Using an integrative approach to the understanding of paradigm gap in host-pathogen interaction studies to the management of Coronavirus patients in the Intensive Care Unit to the current challenges for the effective management of Coronavirus pandemic risk factors including diabetes, hypertension, obesity and repercussion on the central and peripheral nervous system.

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Coronavirus therapeutics ; Vol. I : Basic science and therapy development

Provides the most comprehensive review on contemporary knowledge on the origin and structural biology and molecular aspects of Coronaviruses. This also describes the etiology and pathogeny and therapeutic targets including vaccine drug candidates against Coronaviruses in the light of current scientific knowledge. Using an integrative approach to the understanding of Coronaviruses structure, function and immunobiology, the contributors provide a synopsis of novel mechanisms by which Coronaviruses can be treated.

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Longs COVID-19 patients

Nearly 250 million people around the world have recovered from Covid-19. But here, the word "recovered" refers only to the acute phase of the illness. Approximately 10 and 40 percent of Covid patients continue to experience symptoms several weeks to months after falling sick, a nebulous condition now referred to as post-Covid condition, or long Covid. In long Covid, we are witnessing the emergence of a legitimate new illness, officially recognized by the World Health Organization's International Classification of Diseases...

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Clinical microbiology made ridiculously simple

Is a brief, clear, thorough, and updated approach to clinical microbiology, brimming with mnemonics, humor, summary charts, and illustrations. Topics include Ebola, AIDS, flesh-eating bacteria, mad cow disease, hantavirus, anthrax, smallpox, and tuberculosis; the latest antibiotics; pandemic flu, including H7N9; SARS-like coronavirus; hepatitis C treatment options; HIV diagnostics and approved HIV meds; Zika virus; measles; and a new chapter on the latest emerging infectious diseases and drug-resistant bacteria. The major update to this book is the addition of a new chapter on the SARS-COV-2 virus and COVID-19 disease, which delves into the nature of the virus such as infectivity within the body, transmission between individuals, timeline of infectivity, symptoms, risk factors, therapeutics, and vaccines approved for use.

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Cilia : Methods and protocols

Covers the latest advancements in the study of ciliary complexity. Protocols cover genomic, proteomic, imaging, and functional analysis of different ciliated tissues and their wide applicability in cilia biology. Chapters in this book primarily focus on methods to study multiciliated cells, and discuss topics such as SARS-CoV-2 infections of human primary nasal multiciliated epithelial cells; expansion microscopy of ciliary proteins; live-imaging centriole amplification in mouse brain multiciliated cells; biophysical properties of cilia motility; and mucociliary transport device construction. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

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Alzheimer’s and new horizon

Alzheimer's disease (AD) is characterized by progressive loss of memory and other cognitive functions. This study aims to discuss Alzheimer's disease (AD) and its increasing incidence and related huge fund to take care of such patients and will understand the pathophysiology in order to successfully fight this enigmatic illness and the goal of is the treatment for individuals with AD. Our study will also focus on the mutualistic relationship between AD and SARS- COV-2 infection and its correlation with cancer will be also discussed...

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