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Open access databases and datasets for drug discovery
With an overview of 90 freely accessible databases and datasets on all aspects of drug design, development, and discovery, Open Access Databases and Datasets for Drug Discovery is a comprehensive guide to the vast amount of “free data” available to today’s pharmaceutical researchers. The applicability of open-source data for drug discovery and development is analyzed, and their usefulness in comparison with commercially available tools is evaluated. The most relevant databases for small molecules, drugs and druglike substances, ligand design, protein 3D structures (both experimental and calculated), and human drug targets are described in depth, including practical examples of how to access and work with the data. The first part is focused on databases for small molecules, followed by databases for macromolecular targets and diseases. The final part shows how to integrate various open-source tools into the academic and industrial drug discovery and development process.
Natural Language Processing and Information Systems ; Vol. 3999 ; 11th International Conference on Applications of Natural Language to Information Systems, NLDB 2006, Klagenfurt, Austria, May 31 - June 2, 2006, Proceedings
This book constitutes the refereed proceedings of the 11th International Conference on Applications of Natural Language to Information Systems, NLDB 2006, held in Klagenfurt, Austria in May/June 2006 as part of UNISCON 2006. The book presents 17 revised full papers and 5 revised short papers, organized in topical sections on concepts extraction and ontology, ontologies and task repository utilization, query processing, information retrieval and dialog processing, and NLP techniques.
Morphometrics with R
The R language and environment offers a single platform to perform a multitude of analyses from the acquisition of data to the production of static and interactive graphs. This offers an ideal environment to analyze shape variation and shape change. This open-source language is accessible for novices and for experienced users. Adopting R gives the user and developer several advantages for performing morphometrics: evolvability, adaptability, interactivity, a single and comprehensive platform, possibility of interfacing with other languages and software, custom analyses, and graphs. The book explains how to use R for morphometrics and provides a series of examples of codes and displays covering approaches ranging from traditional morphometrics to modern statistical shape analysis such as the analysis of landmark data, Thin Plate Splines, and Fourier analysis of outlines.
Modeling and Simulation in Scilab
Scilab is a free open-source software package for scientific computation. It includes hundreds of general purpose and specialized functions for numerical computation, organized in libraries called toolboxes, which cover such areas as simulation, optimization, systems and control, and signal processing. One important Scilab toolbox is Scicos. Scicos provides a block diagram graphical editor for the construction and simulation of dynamical systems. The objective of this book is to provide a tutorial for the use of Scilab/Scicos with a special emphasis on modeling and simulation tools. The book is divided into two parts. The first part concerns Scilab and includes a tutorial covering the language features, the data structures and specialized functions for doing graphics, importing, exporting data and interfacing external routines. It also covers in detail Scilab numerical solvers for ordinary differential equations and differential-algebraic equations. Even though the emphasis is placed on modeling and simulation applications, this part provides a global view of Scilab. The second part is dedicated to modeling and simulation of dynamical systems in Scicos. This type of modeling tool is widely used in industry because it provides a means for constructing modular and reusable models. This part contains a detailed description of the editor and its usage, which is illustrated through numerous examples.
High-Performance Modelling and Simulation for Big Data Applications: Selected Results of the COST Action IC1406 cHiPSet
This book is the final compendium of case studies emanated from “High-Performance Modelling and Simulation for Big Data Applications” (cHiPSet).cHiPSet has created a sustainable reference network linking applied research in High Performance Computing (HPC) and Modelling & Simulation to tangibly address Big Data challenges.cHiPSet has also endeavoured to use and exploit results through Open Science practices, i.e., open access publication, open access to data repositories, and open-source software development. A testament to this philosophy, this compendium is set to become a required reference for the fast-changing fields of HPC, Big Data, and Modelling & Simulation.
Hardware Verification with SystemVerilog : An Object-Oriented Framework
Verification is increasingly complex, and SystemVerilog is one of the languages that the verification community is turning to. However, no language by itself can guarantee success without proper techniques. Object-oriented programming (OOP), with its focus on managing complexity, is ideally suited to this task. With this handbook—the first to focus on applying OOP to SystemVerilog—we’ll show how to manage complexity by using layers of abstraction and base classes. By adapting these techniques, you will write more "reasonable" code, and build efficient and reusable verification components. Both a learning tool and a reference, this handbook contains hundreds of real-world code snippets and three professional verification-system examples.
Hardware Verification with C++ : A Practitioner’s Handbook
Part I makes the case for C++, and shows a standard verification system using object-oriented programming (OOP). Part II presents two open-source C++ libraries that enable efficient verification with C++ -- Teal, a C++ to Verilog interface, and Truss, a standard verification framework. Part III focuses on OOP with examples from real verification projects. Part IV puts it all together showing complete block-level and system-level verification systems. "The handbook provides a clear understanding of object-oriented programming, and how it applies to hardware verification. It is clear to me that C++, together with Teal and Truss, could form a strong platform for the next generation of hardware verification."
Designing with the wind : Climate-derived architecture
This book explores wind-adaptive architectural design blending the parametric design with digital simulations and suggests a novel approach for specific, even extreme conditions, as the first step in creating architecture that can act in response to the nature around. The chapters propose an urban and architectural design that emerges from the specific wind microclimate of the design site and responds to the changes in the ambient wind conditions. The book looks closely at A) the interdisciplinary wind-driven design method for architects, engineers, and urbanists employing open-source software for CFD analysis and B) the tensegrity-membrane adaptive building façades.
Market segmentation analysis : Understanding it, doing it, and making It useful
Offers something for everyone working with market segmentation: practical guidance for users of market segmentation solutions; organisational guidance on implementation issues; guidance for market researchers in charge of collecting suitable data; and guidance for data analysts with respect to the technical and statistical aspects of market segmentation analysis. Even market segmentation experts will find something new, including a vast array of useful visualisation techniques that make interpretation of market segments and selection of target segments easier. The book talks the reader through every single step, every single potential pitfall, and every single decision that needs to be made to ensure market segmentation analysis is conducted as well as possible. All calculations are accompanied not only with a detailed explanation, but also with R code that allows readers to replicate any aspect of what is being covered in the book using R, the open-source environment for statistical computing and graphics.
Car deal : The ultimate used-cars marketplace
This is an effort to represents the design and implementation of a mobile application that serves as a marketplace for buying and selling used cars. The application is developed using Flutter, a popular cross-platform framework, and integrates an Artificial Intelligence (AI) model to predict the price of used cars based on various parameters, such as the car's model, age, mileage, and condition. The report provides a comprehensive overview of the project's development process, including the use of agile methodology and various technologies, such as Firebase, Python, and TensorFlow. The AI model's accuracy is evaluated using statistical metrics, such as Mean Absolute Error (MAE) and Root Mean Squared Error (RMSE).
Beginning Ruby on Rails E-Commerce : From novice to professional
Beginning Ruby on Rails E-Commerce: From Novice to Professional is the first book of its kind to guide you through producing e-commerce applications with Rails, the stacked web framework taking the world by storm. The book dives right into the process of creating a production-level web application using agile methodologies and test-driven development combined with Rails best practices.
Beginning PHP and PostgreSQL 8 : From novice to professional
Beginning PHP and PostgreSQL 8 delves into some of the most popular open-source web development technologies, the PostgreSQL 8 database server and PHP 5 scripting language. You'll learn to reap the benefits of these core technologies by using them in unison to create dynamic, data-driven web applications. This is an ideal read if you are a web designer, programmer, hobbyist, or novice who wants to create applications with PHP 5 and PostgreSQL 8.
Beginning PHP and MySQL : From novice to professional
Beginning PHP and MySQL: From Novice to Professional, Third Edition offers a comprehensive introduction to two of the most prominent open-source technologies on the planet: the PHP scripting language and the MySQL database server. Updated to introduce the features found in MySQL's most significant release to date, readers will learn how to take advantage of the features of both technologies to build powerful, manageable, and stable web applications. Essentially three books in one, readers will not only profit from extensive introductions to the core features of each technology, but also learn how to effectively integrate the two in order to build robust data-driven applications.
Beginning JBoss Seam : From novice to professional
Reacting to the popularity of Java 2.0 Enterprise Edition™ alternatives such as Ruby on Rails and the enterprise Spring Framework, Red Hat JBoss®, Inc. developed JBoss® Seam, a new open-source lightweight Java™ EE 5-based contextual application development framework. Beginning JBoss® Seam: From Novice to Professional gets you started as the first book on this popular framework.
Analyzing computer system performance with Perl::PDQ
Analyzing computer system performance is often regarded by most system administrators, IT professionals and software engineers as a black art that is too time consuming to learn and apply. Finally, this book by acclaimed performance analyst Dr. Neil Gunther makes this subject understandable and applicable through programmatic examples. The means to this end is the open-source performance analyzer Pretty Damn Quick (PDQ) written in Perl As the epigraph in this book points out, Common sense is the pitfall of performance analysis. The performance analysis framework that replaces common sense is revealed in the first few chapters of Part I. The important queueing concepts embedded in PDQ are explained in a very simple style that does not require any knowledge of formal probability theory. Part II begins with a full specification of how to set up and use PDQ replete with examples written in Perl. Subsequent chapters present applications of PDQ to the performance analysis of multicomputer architectures, benchmark results, client/server scalability, and Web-based applications.
Agent Intelligence Through Data Mining
AGENT INTELLIGENCE THROUGH DATA MINING offers a self-contained overview of a relatively young but important area of research: the intersection of agent technology and data mining. This intersection leads to considerable advancements in the area of information technologies, drawing the increasing attention of both research and industrial communities. It can take two forms: a) the more mundane use of intelligent agents for improved data mining and; b) the use of data mining for smarter, more efficient agents. The second approach is the main focus of this volume. this book presents a methodology for developing multi-agent systems, describes available open-source tools to support this process, and demonstrates the application of the methodology on three different cases. AGENT INTELLIGENCE THROUGH DATA MINING is designed for a professional audience composed of researchers and practitioners in industry.
6G Mobile Wireless Networks
Specifically, this book covers the following topics: 6G Use Cases, Requirements, Metrics and Enabling Technologies, PHY Technologies for 6G Wireless, Reconfigurable Intelligent Surface for 6G Wireless Networks, Millimeter-wave and Terahertz Spectrum for 6G Wireless, Challenges in Transport Layer for Tbit/s Communications, High-capacity Backhaul Connectivity for 6G Wireless, Cloud Native Approach for 6G Wireless Networks, Machine Type Communications in 6G, Edge Intelligence and Pervasive AI in 6G, Blockchain: Foundations and Role in 6G, Role of Open-source Platforms in 6G, and Quantum Computing and 6G Wireless.
