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Omics sudies of medicinal plants
Herbal drugs play a pivotal role in modern medicine and pharmaceutical care; however, only limited biotechnology applications have been seen in medicinal plants. Revolutions in high-throughput approaches emphasize omics approaches, such as genomics, transcriptomics, proteomics, and metabolomics. A volume in the Exploring Medicinal Plants series, this book provides a comprehensive and in-depth analysis of breakthroughs in high-throughput approaches for the research of medicinal plants.
Metabolomics : The frontier of systems biology
Metabolism is the sum of the chemical reactions in cells that produce life-sustaining chemical energy and metabolites. In the post-genome era, metabolism has taken on new significance for biological scientists: metabolites are the chemical basis of phenotypes that are final expressions of genomic information. This book covers research on metabolomics, ranging from the development of specialized chemical analytical techniques to the construction of databases and methods for metabolic simulation. The authors have been directly involved in the development of all the subject areas, including capillary electrophoresis, liquid chromatography, mass spectrometry, metabolic databases, and metabolic simulation. Breakthrough achievements and the future of metabolome studies are described, making this book a valuable source for researchers in metabolomics in diverse fields, such as plant, animal, cellular, microbial, pharmaceutical, medical, and genetic sciences.
Metabolomics : A powerful tool in systems biology
This book brings together the latest results in the field of metabolomics. It comprehensively presents the current state of the metabolomics field by underscoring experimental methods, analysis techniques, standardization practices, and advances in specific model systems. As a result, it significantly broadens our perspective on the principles and strategies underpinning this emerging field.
Impact of drug-microbiome interactions on drug response
Explains the mechanisms of drug-microbiome interactions, as well as the role of multiomic approaches, including metagenomics, metabolomics, and 16S rRNA sequencing to assess drug response variability. Findings suggest that integrating microbiome profiling into precision medicine could enhance personalized drug therapy, minimize adverse effects and optimize treatment outcomes.
Foodborne bacterial pathogens : Methods and protocols
This updated volume presents a compilation of various representative techniques and approaches currently used to study bacterial foodborne pathogens. Chapters guide the reader through bacterial pathogen detection and quantification in food, molecular, phenotypic, metabolic characterization of food pathogens, and ecology of foodborne bacterial pathogens. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.
Encyclopedia of Human Nutrition
Provides updated information on the foundations of nutrition science, along with the biology and functions of vitamins and other essential nutrients present in the human diet. The book's content offers a modern understanding of the links between diet and health effects, including diseases of recognized nutritional etiology. This overview of the genetic and molecular aspects of nutrient-health interrelationships includes important content on topics like nutrigenomics, metabolomics and the microbiome. In addition, the book provides global context, particularly on the issue of food production, sustainability and climate change.
Comprehensive biochemistry for dentistry : Textbook for dental students
Combines fundamental concepts of biochemistry and the dental sciences to provide an authentic, coherent and comprehensive text for dental students. It describes in simple language the intricate pathophysiology of biomolecules in health and in diseases of dental and oral tissues. This book also describes the evolution of biochemistry in a chronological order, provides information about the fundamental chemical structure, classification and biological significance of biomolecules, vitamins and hormones, enriched with flow charts and diagrams for easy understanding and quick reference. It includes chapters on nucleic acids, nutrition and serum enzymes and organ function tests, and offers an innovative approach to familiarize dental students with the biochemical composition of enamel, dentine, cementum and saliva, explaining the biochemical basis of dental caries, periodontal diseases, role of fluorides in caries prophylaxis, fluoride toxicity, and the role of amino acids as anti-hypersensitive agents
Clinical metabolomics applications in genetic diseases
Helps readers discover the forefront of personalized medicine on clinical metabolomics and its applications in genetic diseases. This comprehensive guide offers a functional relationship map between cell components and genetic variations in various diseases, providing insights that can be applied to personalized medicine. Covers the latest developments in metabolomics for health, with practical guidance for clinical experts looking to advance their laboratory techniques and career. The metabolomics profile is a powerful tool that has revolutionized our understanding of the relationship between genetics, clinical readouts, and disease outcomes. By integrating metabolomics with genomics and clinical phenotypes, the authors have developed diagnostic and prediction models that have vastly improved patient outcomes and deepened the understanding of disease mechanisms.
