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Bacterial virulence factors and Rho GTPases

The authors of this volume present the synthesis on how the various host cellular Rho GTPases activities are manipulated by bacteria to fulfill their virulence.

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Bacterial Biofilms

This volume tends to focus on the biology of biofilms that affect human disease. It opens with chapters that provide the reader with current perspectives on biofilm development, physiology, environmental and regulatory effects, the role of quorum sensing, and resistance/phenotypic persistence to antimicrobial agents during biofilm growth. The next chapters are devoted to common problematic biofilms, those that colonize venous and urinary catheters. The final series of chapters examines biofilm formation by four species that are important pathogens and well studied models, one of which, Yersinia pestis, cleverly adopts a biofilm state of growth within its insect vector to promote disease transmission to mammalian hosts.

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Bacterial and Bacteriophage Genetics

Genetic investigations and manipulations of bacteria and bacteriophage have made vital contributions to our basic understanding of living cells and to the development of molecular biology and biotechnology. This volume is a survey of the genetics of bacteria and their viruses, and it provides students with a comprehensive introduction to this rapidly changing subject. The book is written for upper level undergraduates and beginning graduate students, particularly those who have had an introductory genetics course.

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Cellulose : Molecular and Structural Biology : Selected Articles on the Synthesis, Structure, and Applications of Cellulose

Cellulose: Molecular and Structural Biology is an up-to-date treatise on the most advanced and provocative research into the biosynthesis, structure, and applications of nature’s most abundant macromolecule and renewable resource, cellulose.Molecular, biochemical, and evolutionary aspects of cellulose biosynthesis are reviewed in a variety of living organisms, including cyanobacteria, eubacteria, (Acetobacter, Salmonella, and E. coli), vascular plants (including Arabidopsis, forest trees, and maize), and tunicates.

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Cell Culture Engineering

Many patients suffering with life-threatening diseases or chronic dysfunctions, which were medically untreatable not long ago, can attest to the wonder these drugs have achieved. Although the first generation of p- tein therapeutics was produced in recombinant Escherichia coli, most recent products use mammalian cells as production hosts. Not long after the first p- duction of recombinant proteins in E. coli, it was realized that the complex tasks of most post-translational modifications on proteins could only be efficiently carried out in mammalian cells.

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