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Neurotransmitter Transporters
The present volume of the Handbook of Experimental Pharmacology gives a representative survey of the current status of the structure, function, regulation and molecular pharmacology of Neurotransmitter Transporters and aims at providing an overview of insights that were generated in the past 5 years. If the volume serves as both, a useful compendium of current concepts and an inspiring starting point, it will have fulfilled its mission and will be a source for students interested in this emerging field as well as for experienced scientists looking for an update. This volume is the brainchild of the editor-in-chief of the HEP series, Klaus Starke, awe-inspiring to all pharmacologists of younger generations.
Neurotransmitter Interactions and Cognitive Function
Cognitive function involves the participation of many different neurotransmitter systems in a variety of brain areas. The centerpiece of investigation regarding cognitive function has classically been the cholinergic system, but it has become increasingly clear that other transmitter systems interact with cholinergic systems to provide the neural basis for cognitive function. This book brings together cutting edge research to determine how the transmitter interactions form the mechanistic bases for attention, learning and memory. This research on transmitter interactions not only provides a more accurate, though complex, picture of how the brain works to provide cognitive function, it also provides important new levels of understanding about the mechanisms of cognitive dysfunction and novel avenues for therapeutic treatment. The researchers who contributed to this volume both reviewed the latest findings but also point to the directions of advancement of the field of neurotransmitter interactions and cognitive function.
Monoaminergic modulation of cortical excitability
Monoaminergic Modulation of Cortical Excitability serves as an integrative and comprehensive comparison of the diverse and complex modulatory action of dopamine, noradrenaline, and serotonin receptors in the cortex. The volume is organized into several sections offering a broad spectrum of opinions on how the monoamine systems affect cortical function from a cellular/sub-cellular level to a system level. The complexity of these interactions are discussed in light of recent data showing how disruption of these systems dramatically affects the memory formation and information processing in the cortex.
Exogenous and endogenous factors affecting happiness, happy mind, happy life
Emotions are the language of the soul. Our brain is the emotional center where every emotion is produced including happiness. Happiness underlying factors are considerable from two dimensions: endogenous factors and exogenous factors Therefore, this research aimed to consider biological factors that underlie happiness. The research is divided into several sub-groups (brain, genetics, neurotransmitters, endocrinology, hormones, drugs, diseases, and other exogenous factors). In spite of difficulties in finding special genes, several genes distributed to emotion and mood. Neuroscience studies showed that some part of brain (e.g. amygdala, hipocamp and limbic system) and neurotransmitters (e.g. dopamine, serotonin, norepinefrine and endorphin) play a role in control of happiness. A few studies pointed to the role of cortisol and adrenaline (adrenal gland) and oxitocin (pituitary gland) in controlling happiness.
Ethnopharmacology of Medicinal Plants : Asia and the Pacific
This book presents several aspects of the pharmacology, chemistry, botany and folkloric use of selected medicinal plants that can be found in Asia and the Pacific. It is generously illustrated with line drawings for many of the plants under discussion, as well as examples of chemical structures.
Drugs for Relapse Prevention of Alcoholism
whet there ought to be a reasonable hope that pharmacological drugs will be developed that interfere with an addiction memory, and as a result, finally lead to a cure? In this book, leading preclinical and clinical experts in the field of alcohol relapse prevention strive to furnish an answer to this question. None of the researchers or clinicians believes in a magic bullet that will be of help to all alcoholic patients in overcoming this disease. However, there is now convi- ing evidence demonstrating that specific subpopulations of alcoholic patients experience satisfactory benefit from currently available treatments.
Drug Addiction : From Basic Research to Therapy
Drug Addiction: From Basic Research to Therapy provides a comprehensive overview of physiological, biochemical, genetic and behavioral pathways underlying drug addiction. Focusing on fundamental neurophysiological processes that overlap between drug addiction and other CNS disorders, this volume covers the translation of basic research into novel therapies, not only of drug addiction but a spectrum of related CNS disorders, including pain. Chapters are written by leading scientists with widely ranging expertise in synthetic and computational chemistry, molecular biology, genetics, neurosciences, drug discovery and development, drug targeting, and quantitative therapeutics, providing an unprecedented overview of a complex field of high societal signficance.
Knowledge, practices, and awareness of safety risks associated with antiemetic use: A cross-sectional study
Highlighted a high prevalence of self-medication, with most participants keeping these drugs at home due to their accessibility and low cost. A strong correlation was observed between educational level and awareness; individuals with higher education were more likely to seek professional advice and carefully read drug leaflets. Conversely, lower educational groups and younger participants showed a greater tendency to repeat doses without consultation or rely on home remedies.
Kindling 6
A broad array of themes concerned with research on epilepsy and kindling is covered in the book: Pathogenesis of kindling, including developmental patterns; electrophysiology; anatomy, morphology, and neural circuitry; genes, species, and strains; synaptic pharmacology and neurochemistry ; Behavioral consequences of kindling ; Drugs and interventions against kindling ; Clinical relevance of kindling for our understanding of epilepsy in patients
Antidepressants Beyond Depression, and Into Bacteria
Antidepressants are one of the most predominant drug groups in the pharmaceutical world, primary care units and the general public. Their original use was majorly for the treatment of depression along with other mental disorders. Today, antidepressant consume over 20% of the medical prescriptions and healthcare plans due to their recently discovered applications outside the psychiatry field. Due to the alarming rise of antibiotic resistance and the slow pace of new drug discovery, the world has been searching frantically for new or alternative drugs with antibacterial activity. Repurposing already FDA- approved drugs for uses that are off-label has become an important preposition in the pharmacy world due to its availability, low risk and low cost.
