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CADD and informatics in drug discovery
Updates knowledge on recent advances in computational and bioinformatics tools/techniques and their practical applications in modern drug design and discovery programme. Also it encompasses fundamental principles, advanced methodologies and applications of various CADD approaches including several cutting-edge areas / presenting recent developments covering ongoing trends in the field of computer-aided drug discovery. Having contributions by a global team of experts, the book is expected to be an ideal resource for drug discovery scientists, medicinal chemists, pharmacologists, toxicologists, phytochemists, biochemists, biologists, RandD personnel, researchers, students, teachers and those working in the field of drug discovery. It will fill the knowledge gaps that exist in the current CADD approaches and methodologies/ protocols being widely used in both academic and research practices. Further, a special focus on current status of various computational drug design approaches (SBDD, LBDD, De-novo drug design, Pharmacophore-based search), bioinformatics tools and databases, computational screening and modeling of phytochemicals/natural products, artificial intelligence and machine learning, and network pharmacology and system biology would certainly guide researchers, students or readers to conduct their research in the emerging area(s) of interest. It is also expected to be highly beneficial to different stakeholders working in the pharmaceutical and biotechnology industries (RandD), the academic as well as research sectors. .
Bioinformatics of genome regulation and structure II
The conference was organized by the Laboratory of Theoretical Genetics, Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia. The material covers the most recent topics in bioinformatics, including (i) regulatory genomic sequences: databases, knowledge bases, computer analysis, modeling, and recognition; (ii) large-scale genome analysis and functional annotation; (iii) gene structure detection and prediction; (iv) comparative and evolutionary genomics; (v) computer analysis of genome polymorphism and evolution; computer analysis and modeling of transcription, splicing, and translation; structural computational biology: structure- function organization of genomic DNA, RNA, and proteins; (vi) gene networks, signal transduction pathways, and genetically controlled metabolic pathways: databases, knowledge bases, computer analysis, and modeling; principles of organization, operation, and evolution; (vii) data warehousing, knowledge discovery and data mining; and (viii) analysis of basic patterns of genome operation, organization, and evolution.
Bioinformatics and systems biology : Collaborative research and resources
Collaborative research in bioinformatics and systems biology is a key element of modern biology and health research. This book highlights and provides access to many of the methods, environments, results and resources involved, including integral laboratory data generation and experimentation and clinical activities. Collaborative projects embody a research paradigm that connects many of the top scientists, institutions, their resources and research worldwide, resulting in first-class contributions to bioinformatics and systems biology. Central themes include describing processes and results in collaborative research projects using computational biology and providing a guide for researchers to access them. The book is also a practical guide on how science is managed. It shows how collaborative researchers are putting results together in a way accessible to the entire biomedical community.
Applied Bioinformatics : An Introduction
In this book, anyone who can operate a PC, standard software and the Internet will learn to understand the biological basis of bioinformatics of the existence as well as the source and availability of bioinformatics software how to apply these tools and interpret results with confidence.This is aided by introductory chapters to important aspects of bioinformatics, detailed bioinformatics exercises, including solutions and a glossary of definitions and terminology relating to bioinformatics.
Mastering Oracle SQL and SQL*Plus
This exceptional book explains fundamentals in detail, supported by realistic examples, while most other books on the market do not properly cover such basics. If you work with relational databases you need to understand the SQL language. And you will gain full competence to define, access, and manipulate data in an Oracle database, if you do so following this book's guidance.
Managing Cyber Threats : Issues, Approaches, and Challenges
Brings together the latest techniques for managing cyber threats, developed by some of the world’s leading experts in the area. The book includes broad surveys on a number of topics, as well as specific techniques. It provides an excellent reference point for researchers and practitioners in the government, academic, and industrial communities who want to understand the issues and challenges in this area of growing worldwide importance.
Machine Learning Techniques and Analytics for Cloud Security
covers new methods, surveys, case studies, and policy with almost all machine learning techniques and analytics for cloud security solutions
Machine Learning for Multimedia Content Analysis
Challenges in complexity and variability of multimedia data have led to revolutions in machine learning techniques. Multimedia data, such as digital images, audio streams and motion video programs, exhibit richer structures than simple, isolated data items. A number of pixels in a digital image collectively conveys certain visual content to viewers. A TV video program consists of both audio and image streams that unfold the underlying story. To recognize the visual content of a digital image, or to understand the underlying story of a video program, we may need to label sets of pixels or groups of image and audio frames jointly.
Machine learning for data streams : With practical examples in MOA
The book first offers a brief introduction to the topic, covering big data mining, basic methodologies for mining data streams, and a simple example of MOA. More detailed discussions follow, with chapters on sketching techniques, change, classification, ensemble methods, regression, clustering, and frequent pattern mining. Most of these chapters include exercises, an MOA-based lab session, or both. Finally, the book discusses the MOA software, covering the MOA graphical user interface, the command line, use of its API, and the development of new methods within MOA.
Long-Term Preservation of Digital Documents : Principles and Practices
Key to our culture is that we can disseminate information, and then maintain and access it over time. While we are rapidly advancing from vulnerable physical solutions to superior, digital media, preserving and using data over the long term involves complicated research challenges and organization efforts. Uwe Borghoff and his coauthors address the problem of storing, reading, and using digital data for periods longer than 50 years. They briefly describe several markup and document description languages like TIFF, PDF, HTML, and XML, explain the most important techniques such as migration and emulation, and present the OAIS (Open Archival Information System) Reference Model. To complement this background information on the technology issues the authors present the most relevant international preservation projects, such as the Dublin Core Metadata Initiative, and experiences from sample projects run by the Cornell University Library and the National Library of the Netherlands. A rated survey list of available systems and tools completes the book.
Logical Data Modeling : What it is and How to do it
LOGICAL DATA MODELING: What It Is and How To Do IT is directed toward three groups of people: (1) Business subject matter experts, (2) information technology professionals, (3) advanced students in Computer Science, Management Information Systems, and e-Business. Its purpose is to outline the basics of logical data modeling—specifically, data modeling for relational database management systems—in simple, practical terms and in a business context. The focus on relational data modeling is consciously made because it is superior in modeling real business activities.
Logical and Relational Learning
This textbook covers logical and relational learning in depth, and hence provides an introduction to inductive logic programming (ILP), multirelational data mining (MRDM) and (statistical) relational learning (SRL). These subfields of data mining and machine learning are concerned with the analysis of complex and structured data sets that arise in numerous applications, such as bio- and chemoinformatics, network analysis, Web mining, natural language processing, within the rich representations offered by relational databases and computational logic.
LINQ for Visual C# 2008
Every C# programmer needs to learn about LINQ (Language–Integrated Query), Microsoft's breakthrough technology for simplifying and unifying data access from any data source. With LINQ, you can write more elegant and flexible code—not just to access databases and files, but to manipulate data structures and XML. This book is a short, yet comprehensive guide to the major features of LINQ and the significant enhancements introduced with .NET 3.5. There is no better source for getting a head–start on the future of these technologies than this book.
LINQ for Visual C# 2005
LINQ for Visual C# 2005 is a short, yet comprehensive guide to the major features of LINQ. It thoroughly covers LINQ to Objects, LINQ to SQL, LINQ to DataSet, and LINQ to XML. It also details significant enhancements to C#, .NET, and ADO.NET.
Linked Open Data -- Creating Knowledge Out of Interlinked Data : Results of the LOD2 Project
Linked Open Data (LOD) is a pragmatic approach for realizing the Semantic Web vision of making the Web a global, distributed, semantics-based information system. This book presents an overview on the results of the research project “LOD2 -- Creating Knowledge out of Interlinked Data”. LOD2 is a large-scale integrating project co-funded by the European Commission within the FP7 Information and Communication Technologies Work Program. Commencing in September 2010, this 4-year project comprised leading Linked Open Data research groups, companies, and service providers from across 11 European countries and South Korea.
Knowledge graphs and big data processing
This book is part of the LAMBDA Project (Learning, Applying, Multiplying Big Data Analytics), funded by the European Union, GA No. 809965. Data Analytics involves applying algorithmic processes to derive insights.
Knowledge and Skill Chains in Engineering and Manufacturing : Information Infrastructure in the Era of Global Communications
Explores knowledge and skill chains in engineering and manufacturing in the age of global communications. Information infrastructure involves a range of activities from product planning, engineering, and manufacturing trough transportation, marketing, and repair/upgrade to returns and recycling/disposal. Distinct from the traditional engineering database, life-cycle support information has its own characteristic requirements, -- flexible extensibility, distributed architecture, multiple viewpoints, long-time archiving, and product usage information. Several authors address the architecture of the information infrastructure, its services and its requirements. Other papers focus on the knowledge and skill chains that develop in a variety of situations: the supply chain, the factory floor, the man-system interaction, etc. For each of these, state-of-the-art and state-of-research scenarios for various industrial sectors address both engineering and operations requirements in the current socio-economic environment.
Knowledge and Data Management in GRIDs
Knowledge and Data Management in GRIDs is the third volume of the CoreGRID series and brings together scientific contributions by researchers and scientists working on storage, data, and knowledge management in GRID and Peer-to-Peer systems. This volume presents the latest GRID solutions and research results in key areas of knowledge and data management such as distributed storage management, GRID databases, Semantic GRID and GRID-aware data mining.
Journal on Data Semantics XI
The LNCS Journal on Data Semantics is devoted to the presentation of notable work that, in one way or another, addresses research and development on issues related to data semantics. The scope of the journal ranges from theories supporting the formal definition of semantic content to innovative domain-specific applications of semantic knowledge. The journal addresses researchers and advanced practitioners working on the semantic web, interoperability, mobile information services, data warehousing, knowledge representation and reasoning, conceptual database modeling, ontologies, and artificial intelligence.
Journal on Data Semantics X
Web semantics and semi-structured data , Semantic caching , Data warehousing and semantic data mining , Spatial, temporal, multimedia and multimodal semantics , Semantics in data visualization , Semantic services for mobile users , Supporting tools , Applications of semantic-driven approaches These topics are to be understood as specifically related to semantic issues. Contributions submitted to the journal and dealing with semantics of data will be considered even if they are not from the topics in the list. While the physical appearance of the journal issues is like the books from the we- known Springer LNCS series, the mode of operation is that of a journal. Contributions can be freely submitted by authors and are reviewed by the Editorial Board.
