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Singular Perturbation Theory : Mathematical and Analytical Techniques with Applications to Engineering
Singular Perturbation Theory introduces all the background ideas to this subject, designed for those with only the most superficial familiarity with university-level mathematics. The methods are developed through worked examples and set exercises (with answers); the latter part of the book is devoted to applications drawn from: mechanics, physics, semi- and superconductor theory, fluid mechanics, thermal processes, chemical and biochemical reactions. In a novel approach, these are grouped together so that the reader with particular interests can readily access them.
Single Molecules and Nanotechnology
Focuses on recent advances in the rapidly evolving field of single molecule research. These advances are of importance for the investigation of biopolymers and cellular biochemical reactions, and are essential to the development of quantitative biology. Written by leading experts in the field, the articles cover a broad range of topics, including : quantum photonics of organic dyes and inorganic nanoparticles / their use in detecting properties of single molecules / the monitoring of single molecule (enzymatic) reactions / single protein (un) / olding in nanometer-sized confined volumes / the dynamics of molecular interactions in biological cells
Formal Methods in Systems Biology ; 1st International Workshop, FMSB 2008, Cambridge, UK, June 4-5, 2008. Proceedings
This book constitutes the refereed proceedings of the First International Workshop on Formal Methods in Systems Biology, FMSB 2008, held in Cambridge, UK, in June, 2008.The 9 revised full papers presented were carefully reviewed and selected from the workshop lectures that all were invited contributions. The purpose of this meeting was to identify techniques for the specification, development and verification of biological models. It also focused on the design of tools to execute and analyze biological models that can significantly advance our understanding of biological systems.
Enzymes and drugs
Enzyme dysfunction, an essential catalyst for the smooth running of biochemical reactions and the maintenance of vital processes, is at the root of many pathologies that have paved the way for the development of numerous drugs. Aimed at pharmacists, biologists, biochemists, doctors, veterinarians, medicinal chemists and students from a wide range of disciplines, Enzymes and Drugs brings together, for the first time, extensive documentation highlighting the relationships between a large number of drugs and enzymes. The book also highlights new prospects for therapeutic discoveries offered by enzyme targeting. Numerous applications have been developed thanks to strategies for studying enzyme inhibition or activation, as well as the development of allosteric effectors, presented with their advantages and disadvantages. Various rare diseases, known as "orphan" diseases, have resulted from enzyme deficiency or absence. For their treatment, the introduction of substitute enzymes has led to major therapeutic advances.
Computational methods in systems biology ; Vol. 4210 ; International Conference, CMSB 2006, Trento, Italy, October 18-19, 2006, Proceedings
This book constitutes the refereed proceedings of the International Conference on Computational Methods in Systems Biology, CMSB 2006, held in Trento, Italy, in October 2006. The papers present a variety of techniques from computer sciences, such as language design, concurrency theory, software engineering, and formal methods.
Computational methods in systems biology ; International Conference CMSB 2007, Edinburgh, Scotland, September 20-21, 2007, Proceedings
This book presented present a variety of techniques from computer science, such as language design, concurrency theory, software engineering, and formal methods, for biologists, physicists, and mathematicians interested in the systems-level understanding of cellular processes.
Computational methods in systems biology ; 6th International Conference CMSB 2008, Rostock, Germany, October 12-15, 2008. Proceedings
This book constitutes the refereed proceedings of the 6th International Conference on Computational Methods in Systems Biology, CMSB 2008, held in Rostock, Germany, in September 2008.
Bioinformatics drug discovery
Quantitative tools are becoming increasingly important in order to understand complex cascade of signal transduction events, pathways or biochemical reactions. The book showcases how computational techniques and algorithms are applied to biological data analysis, interpretation, and modelling. It covers applications in drug design and discovery, immune systems, phylogenetic analysis and protein structures.
Biochemistry
Biochemistry and the organization of cells -- Water : the solvent for biochemical reactions -- Amino acids and peptides -- The three-dimensional structure of proteins -- Protein purification and characterization techniques -- The behavior of proteins : enzymes -- The behavior of proteins : enzymes, mechanisms, and control -- Lipids and proteins are associated in biological membranes -- Nucleic acids : how structure conveys information -- Biosynthesis of nucleic acids : replication -- Transcription of the genetic code : the biosynthesis of RNA -- Protein synthesis : translation of the genetic message -- Nucleic acid biotechnology techniques -- Viruses, cancer, and immunology -- The importance of energy changes and electron transfer in metabolism -- Carbohydrates -- Glycolysis
