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Neurocutaneous disorders : A clinical, ciagnostic and therapeutic approach

Provides extensive data on the more common and many of the more rare congenital and hereditary syndromes that manifest in the nervous system and skin. Though often complex and multi-systemic, these disorders can frequently be diagnosed using a combination of simple visual inspection and sound clinical expertise. Drawing on fully referenced information from thousands of articles, the international editorial team has prepared a comprehensive overview that includes historical perspectives, clinical features, the pathogenesis, and diagnostic and therapeutic strategies. In addition, it addresses the biochemical, molecular, and genetic basis of the disorders.

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Neuroactive Steroids in Brain Function, Behavior and Neuropsychiatric Disorders : Novel Strategies for Research and Treatment

Over the past few decades the involvement of neurosteroids in brain function and mental health has attracted much interest, not only from a neuroscience perspective, but also from clinical and therapeutic aspects. In recent years, much of the research has focused on the multifunctional position of neurosteroids in the nervous system. The areas that have been explored, in particular, are the cellular and molecular mechanisms involved in the activity of neurosteroids in the brain, the role of neurosteroids in brain development, neurodegeneration and neuroplasticity, and their pharmacological properties. The large increase in the number of publications highlights this amplified interest in neurosteroids. Over the last 7 years at least 400 papers have been published describing the putative role of neurosteroids in the modulation of basic brain function and in the etiology and treatment of psychiatric and neurological disorders.

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Neuroacanthocytosis Syndromes II

Awareness of neuroacanthocytosis disorders has increased significantly in recent years. There have been a number of important developments in the field since the publication of the first volume, Neuroacanthocytosis Syndromes. This book contains the latest research in this area. Recent advances have identified the range of mutations in the causative genes, shedding light on potential phenotype­genotype correlations. Studies of the proteins affected in these disorders have resulted in increased understanding of their functions and distribution. In vitro studies have identified potential protein interactions, which have important implications for pathophysiology. Work on erythrocyte membranes suggests mechanisms for the generation of acanthocytes. Animal models are being generated which will greatly facilitate understanding the role of gene mutations in humans, and provide the foundation for possible therapeutic interventions. In addition, advances in other neurodegenerative disorders, such as Huntington’s and Parkinson’s diseases, have implications for neuroacanthocytosis.

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Neural Network Driven Artificial Intelligence : Decision Making Based On Fuzzy Logic

Artificial Intelligence, Computer Science and Internet, Computer Science, Technology and Applications, Mathematics Research Developments

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Neural Crest Induction and Differentiation

Neural Crest Induction and Differentiation, written by an international panel of recognized leaders in the field, discusses all aspects of modern neural crest biology from its evolutionary significance, to its specification, migration, plasticity and contribution to multiple lineages of the vertebrate body, to the pathologies associated with abnormal neural crest development and function. Each chapter provides an invaluable resource for information on the most current advances in the field, with discussion of controversial issues and areas of emerging importance.

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Networking and Mobile Computing ; 3rd International Conference, ICCNMC 2005, Zhangjiajie, China, August 2-4, 2005, Proceedings

The objective of this conference was to address and capture highly innovative and stateof-the-art research and work in the networks and mobile computing industries. ICCNMC 2005 allowed sharing of the underlying theories and applications, and the establishment of new and long-term collaborative channels aimed at developing innovative concepts and solutions geared to future markets. The highly positive response to ICCNMC 2001 and ICCNMC 2003, held in Beijing and Shanghai, respectively, encouraged us to continue this international event. In its third year, ICCNMC 2005 continued to provide a forum for researchers, professionals, and industrial practitioners from around the world to report on new advances in computer network and mobile computing, as well as to identify issues and directions for research and development in the new era of evolving technologies.

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Networked Neighbourhoods : The Connected Community in Context

The setting for this book is the networked community. The treatment of the subject matter is broad and interdisciplinary, with contributions from computer science, sociology, design, human factors and communication technology. The chapter contributors, drawn from across Europe and North America, offer a varied prospectus of commentary, critique, sociological enquiry, technological development and research findings, which provides a rounded account of the progressive intermingling of social and electronic networks.

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Networked Embedded Sensing and Control ; Workshop NESC'05 : University of Notre Dame, USA, October 2005 Proceedings

Recent technological developments in sensing, communications, control and computation have created an emerging class of complex systems hereon called networked embedded systems. These systems can be roughly described as collections of spatially distributed sensors, actuators and controllers whose behaviour is coordinated through wired or wireless communication links. This integration between different technologies and scientific domains presents new and challenging fundamental problems underlying the theoretical foundations for this class of systems. This workshop aims at bringing together researchers working of different aspects of networked embedded systems in order to exchange research experiences and to identify the main scientific challenges in this exciting new area.

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Networked Control Systems: Theory and Applications

Networked Control Systems presents the most recent results in stability and robustness analysis as well as new developments related to networked fuzzy and optimal control. Many of the chapters contain details of case-studies, experimental, simulation and/or other application-related work showing how the theories put forward can be implemented in real systems.

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Network-Centric Collaboration and Supporting Frameworks ; IFIP TC 5 WG 5.5, Seventh IFIP Working Conference on Virtual Enterprises, 25-27 September 2006, Helsinki, Finland

This book contains a number of selected articles from PRO-VE’06, the seventh working conference on virtual enterprises held in Helsinki, Finland, which was sponsored by the International Federation for Information Processing (IFIP) and the Society of Collaborative Networks (SOCOLNET). Being recognized as the most focused scientific and technical conference on Collaborative Networks, PRO-VE continues offering the opportunity for presentation and discussion of both the latest research developments as well as the practical application case studies. Following the vision of IFIP and SOCOLNET, the PRO-VE conference offers a forum for collaboration and knowledge exchange among experts from different regions of the world.

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Net-Centric Approaches to Intelligence and National Security

Net-Centric Approaches to Intelligence and National Security considers the web architectures and recent developments that make net-centric approaches for intelligence and national security possible. The development of net-centric approaches for intelligence, national & homeland security applications has become a major concern in many areas such as defense intelligence and national and international law enforcement agencies, especially since the terrorist attacks of 9/11. Net-Centric Approaches to Intelligence and National Security presents developments in information integration and recent advances in web services including the concept of the semantic web. Discovery analysis and management of web-available data pose a number of interesting challenges for research in web-based management systems. Intelligent agents and data mining are among the techniques employed. A number of specific systems that are net-centric based in various areas of military applications, intelligence and law enforcements are presented utlilizing one or more of such techniques Net-Centric Approaches to Intelligence and National Security is designed for a professional audience of researchers and practitioners in industry. This volume is also suitable for graduate-level students in computer science.

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Net Neutrality or Net Neutering : Should Broadband Internet Services Be Regulated

The subject of this book – whether or not to extend traditional telecommunications regulation to high-speed or "broadband" access to the Internet – is perhaps the most important issue now facing the Federal Communications Commission. The issue is also very contentious, with influential economic interests as well as academics on both sides of the question. Content providers – Microsoft and Amazon, for instance – argue that broadband providers should be treated as common carriers, required to transmit all content in a nondiscriminatory way. The broadband providers – the telephone and cable companies – argue that no bottleneck monopoly exists to justify such regulation and that, if imposed, it would stifle development of the Internet.

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Nephrology Worldwide

This book presents contributions from leading international experts in the field of nephrology. Each chapter is independent and discusses nephrology in the author’s country, including the history of nephrology development, kidney disease epidemiology, clinical nephrology, dialysis practice in acute and chronic renal failure settings (hemodialysis, hemodiafiltration, peritoneal dialysis), pediatric nephrology, and kidney transplantation. In addition, the book covers topics such as the job market for nephrologists, reimbursement, nephrology education, and the number of professionals in the private and public sectors.

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Neonatal Pain : Suffering, Pain and Risk of Brain Damage in the Fetus and Newborn

Until the 1980s it was denied that fetuses and neonates feel pain. With the advent of a deeper understanding of the pathophysiology and new diagnostic tools, the last 30 years have seen great developments in this field. This volume aims to give an overview of current knowledge in the field.

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Neonatal Immunity

New advances in cellular immunology, molecular biology, recombinant DNA and proteins, and the function of cytokines and chemokines have revolutionized the study of neonatal immune responsiveness. In Neonatal Immunity, Constantin Bona, MD, critically reviews the classic, as well as most recent-and quite seminal-findings concerning the phenotypic and molecular characteristics of both fetal and neonatal B and T cells, the cells that mediate antibody and cellular immune responses in newborns and infants. Dr. Bona shows how the antibody response of neonates is modulated by maternal antibodies and how, in certain cases, this can cause transient or life-threatening neonatal autoimmune disease. He also describes the characteristics of neonatal tolerance induced by foreign allo- and self-antigens, which are the basis for understanding impaired infant immune response and which provide a rationale for the development of efficient neonatal vaccines. By making clear the characteristics and differences between the immune system and the immune responses of both newborns and infants, compared to those of adults, Dr. Bona offers insights and challenging hypotheses that promise to help overcome the poor responses of neonates to various antigens. Authoritative and forward-looking, Neonatal Immunity critically reviews what we know of the neonatal immune response today, and how this is dramatically opening new therapeutic horizons in such areas as infant vaccination, stem cells, gene therapy, and transplantation.

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Neighbourhoods in Transition : Brownfield Regeneration in European Metropolitan Areas

This book is focused on the intersection between urban brownfields and the sustainability transitions of metreopolitan areas, cities and neighbourhoods. It provides both a theoretical and practical approach to the topic, offering a thorough introduction to urban brownfields and regeneration projects as well as an operational monitoring tool.

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Neglected tropical diseases and phytochemicals in drug discovery

Neglected Tropical Diseases and Phytochemicals in Drug Discovery delivers a comprehensive exploration of the drug discovery process as it pertains to neglected tropical diseases. The book covers recent advancements in drug discovery, as well as druggable targets and new challenges facing the industry. It offers readers expansive discussions of specific diseases, including protozoan, helminth, bacterial, viral, fungal, and ectoparasitic infections.

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Nearrings and Nearfields ; Proceedings of the Conference on Nearrings and Nearfields, Hamburg, Germany July 27 - August 3, 2003

This present volume is the Proceedings of the 18th International Conference on Nearrings and Nearfields held at the Helmut-Schmidt-Universitat, Universitat der Bundeswehr Hamburg, from July 27-August 3, 2003. It contains the written versions of the lectures by the five invited speakers. These concern recent developments of planar nearrings, nearrings of mappings, group nearrings and loop-nearrings. One of them is a long and very substantial research paper "The Z-Constrained Conjecture". These are followed by 13 contributions reflecting the diversity of the subject of nearrings and related structures. Besides the purely algebriac structure theory, these papers show many connections of nearring theory with group theory, combinatorics, geometries, and topology, and all contain original research.

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Neanderthals Revisited : New Approaches and Perspectives

This volume presents cutting-edge research by leading scientists re-examining the major debates in Neanderthal research with the use of innovative state-of-the art methods and exciting new theoretical approaches.Topics addressed include the re-evaluation of Neanderthal anatomy, inferred adaptations and habitual activities, developmental patterns, phylogenetic relationships, and the Neanderthal extinction; new methods include computer tomography, 3D geometric morphometrics, ancient DNA and bioenergetics. The diverse contributions offer fresh insights and advances in Neanderthal and modern human origins research.

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Nb3Sn Accelerator Magnets : Designs, Technologies and Performance

This book is written by world-recognized experts in the fields of applied superconductivity and superconducting accelerator magnet technologies. It provides a contemporary review and assessment of the experience in research and development of high-field accelerator dipole magnets based on Nb3Sn superconductor over the past five decades. The reader attains clear insight into the development and the main properties of Nb3Sn composite superconducting wires and Rutherford cables, and details of accelerator dipole designs, technologies and performance. Special attention is given to innovative features of the developed Nb3Sn magnets. The book concludes with a discussion of accelerator magnet needs for future circular colliders.

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