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Cellular Automaton Modeling of Biological Pattern Formation: Characterization, Applications, and Analysis

This book focuses on a challenging application field of cellular automata: pattern formation in biological systems, such as the growth of microorganisms, dynamics of cellular tissue and tumors, and formation of pigment cell patterns. These phenomena, resulting from complex cellular interactions, cannot be deduced solely from experimental analysis, but can be more easily examined using mathematical models, in particular, cellular automaton models.

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Cathodic Arcs : From Fractal Spots to Energetic Condensation

Cathodic Arcs: From Fractal Spots to Energetic Condensation is the first book in over a decade dedicated to the physics and technology of cathodic arcs. It includes a detailed account of arc history, a textbook-like introduction to cathode phenomena, and some basic physics of expanding plasmas; it deals with the infamous macroparticle issue and describes a host of practical plasma filter solutions. In contrast to previous books on cathodic arcs, the focus is on the relation of arc plasmas and their properties to surface modification and thin film deposition. The book contains sections on basic plasma physics and thin film materials science. It also deals with practical issues of coatings such as stress control and the often-underrated issue of the coating’s color. By stressing the fractal nature of cathode spots, the theme of fluctuations can be found throughout the book: fluctuations affect all plasma properties and thereby have consequences for plasma-based surface modifications and film growth.

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Casting : An Analytical Approach

For a long time, the die cast industry has used trial and error as a leading development method, resulting in tremendous growth in the utilisation of available CFD (computational fluid dynamics) software. This software allows the development of better products that maximise the advantages the die cast process has to offer. Casting: An Analytical Approach will refresh knowledge of the governing laws of the fluid dynamics that have an effect on die cast die and die cast process design. MATLAB® (MathWorks, Inc.) and Visual Basic® (Microsoft) code are listed in Casting: An Analytical Approach for every stage of product, die and die cast process design; providing better understanding of die and process design and simplifying calculations of the die cast die as well as the die cast process. Gas ventilation system calculations and fundamentals of compressible gas flow are also included.

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Career development in bioengineering and biotechnology : Roads well laid and paths less traveled

Career Development in Bioengineering and Biotechnology is an indispensable guide to some of the most exciting career and professional growth opportunities in science, engineering, and beyond, and a "must read" for anyone interested in a career related to this burgeoning field.

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Carbon : The future material for advanced technology applications

Carbon-based materials and their applications constitute a burgeoning topic of scientific research among scientists and engineers attracted from diverse areas such as applied physics, materials science, biology, mechanics, electronics and engineering. Further development of current materials, advances in their applications, and discovery of new forms of carbon are the themes addressed by the frontier research in these fields. This book covers all the fundamental topics concerned with amorphous and crystalline C-based materials, such as diamond, diamond-like carbon, carbon alloys, carbon nanotubes. The goal is, by coherently progressing from growth - and characterisation techniques to technological applications for each class of material, to fashion the first comprehensive state-of-the-art review of this fast evolving field of research in carbon materials.

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Cancer

The last decade has seen a dramatic shift in anticancer drug research towards agents that aim to target selectively key regulatory and signaling processes known to drive tumorigenesis. A number of these newer agents have now been introduced into clinical practice. This volume reviews advances in cancer chemotherapy research over the last 10 years and will be of interest to scientists engaged in drug research in the pharmaceutical industry, biotechnology and startup companies, academia and government institutions. Chapters written by leading experts in their field reflect a range of current medicinal chemistry approaches to small molecule drugs, including anti-hormonal therapy, growth factor inhibition, survival signaling, cell cycle inhibition, anti-angiogenics and anti-nvasives. Each chapter aims to cover the drug target and biological rationale, chemotypes, clinical status and future prospects in this rapidly developing area of drug research.

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Calibrating the Cosmos : How Cosmology Explains Our Big Bang Universe

Calibrating the Cosmos describes hard science, but is gently written. It explains in clear, non-mathematical language the measurements and the interpretation of the resulting data that have led to the current understanding of the origin, evolution and properties of our expanding Big Bang universe. Many people have a sketchy idea of the work of cosmologists, but Professor Levin’s experience in teaching both scientific and liberal arts students has enabled him to impart much of our current thinking without resorting to difficult mathematics. Theoretical concepts are emphasized, in particular the symmetries of homogeneity and isotropy enjoyed by our universe on the largest scales, how these symmetries lead to only one quantity being needed to describe the growth of the universe from its infancy to the present time, and how the so-called parameters of the universe are the ingredients used to construct the model universes to which ours – the real thing – is compared.

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Browning Agents and Active Particles : Collective Dynamics in the Natural and Social Sciences

Lays out a vision for a coherent framework for understanding complex systems'' (from the foreword by J. Doyne Farmer). By developing the genuine idea of Brownian agents, the author combines concepts from informatics, such as multiagent systems, with approaches of statistical many-particle physics. This way, an efficient method for computer simulations of complex systems is developed which is also accessible to analytical investigations and quantitative predictions. The book demonstrates that Brownian agent models can be successfully applied in many different contexts, ranging from physicochemical pattern formation, to active motion and swarming in biological systems, to self-assembling of networks, evolutionary optimization, urban growth, economic agglomeration and even social systems.

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Bone Morphogenetic Proteins : From Local to Systemic Therapeutics

Tissue engineering is gaining interest as it is applied for regeneration of organs to attain their lost function. Although resorbable scaffolds and progenitor cell types are required principles to engineer a functional tissue locally, the inductive signal is a prerequisite to trigger the growth and differentiation of responding cells in space and time. Bone morphogenetic proteins (BMPs), also called growth and differentiation factors (GDFs), originally identified from bone have been successfully used to regenerate the bone in humans. Most recent preclinical data suggests that BMPs have a potential to provide protection against inflammation and fibrosis in acute and chronic injury of parenchymal tissues when applied systemically to sustain the function of kidney and liver. The application of BMPs from a local to systemic utility is a rapidly growing field, gaining interest among researchers and biotech entrepreneurs.

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Binary Rare Earth Oxides

The book begins with a brief introduction to binary rare earth oxides, their physical and chemical stabilities, polymorphism, crystal structures and phase transformation and the association with current applications. The book goes on to present the band structure of the oxides using several quantum chemical calculations, which belong to a newly developed area in the binary rare earth oxides. Central to this chapter are the characterizations of electrical, magnetic and optical properties, as well as details of single crystal growth and particle preparation methods that have progressed in recent years. Later chapters concentrate on thermo-chemical properties and trace determination techniques. The final chapter contains a variety of useful applications in various fields such as phosphors, glass abrasives, automotive catalysts, fuel cells, solid electrolytes, sunscreens, iron steels, and biological materials.

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Beauty’s Appeal : Measure and Excess

Beauty fulfils human existence. As it registers in our aesthetic experience, beauty enhances nature’s enchantment around us and our inward experience lifting our soul toward moral elevation. Carried by creative imagination (Imaginatio Creatrix), beauty participates in the moulding of the forms of the intellective constitution of the mind in tandem with praxis and seeks deeper enigmas of the real in the labyrinth of the cosmos. Yet with the evolution of human development and in technological inventions, beauty, while suffusing all modalities of experience, seems to undergo transformations and expansion. Are there perduring norms and modalities of beauty or are we carried along blindly by human development? Is there a measure intrinsic to our human ontopoietic unfolding and the growth of human life that we may follow instead of the whim of fancy and excess? The present collection of art-explorations seeks the elemental ties of Human Condition. Together, the authors aim to answer the questions posed above.

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Asian-Pacific coasts and their management : States of environment

The Asia-Pacific region is home to the world’s largest region of coral reefs and mangroves. It accommodates two-thirds of the world’s human population and its economic activities have the highest growth rate in the world. Ongoing degradation of the environment, resulting from coastal development, deforestation, desertification and over-harvesting, are becoming a matter of great concern, as floods and droughts occur as a result of this degradation. Threats of global environmental change, such as climate change and sea-level rise, will exacerbate such problems. Therefore, appropriate policies and measures are needed for coastal management, to address both the local and global trends. This book gives an overview of the state-of-the-art understanding on the drivers, state, and responses to coastal environmental changes in the Asia-Pacific region. It provides excellent perspectives on current and anticipated environmental changes in the region’s coastal areas, to researchers, students, policy makers, coastal managers and other stakeholders.

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Asian century … on a knife-edge : A 360 degree analysis of Asia's recent economic development

This book delves into the widely held belief that the 21st century will be the "Asian Century" by examining the Asia's rapid economic development in the post-war era and the challenges it faces in forging ahead of world leaders in the West. The impact of the current turbulent global political climate on Asia is critically analyzed, employing a holistic and multidisciplinary approach, combining economic, social, political and geopolitical perspectives. Written in an accessible style, the book offers students, business, government, and civil society players powerful insights on Asia.

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Applying the Kaizen in Africa : A New Avenue for Industrial Development

At present, how to develop industries is a burning issue in Africa, where population growth remains high and economic development has thus far failed to provide sufficient jobs for many, especially young people and women. The creation of productive jobs through industrial development ought to be a central issue in steering economic activity across the continent.The authors of this book, consisting of two development economists and five practitioners, argue that the adoption of Kaizen management practices, which originated in Japan and have become widely used by manufacturers in advanced and emerging economies, is decisively the most effective first step for industrial development in Africa.This open access book discusses what Kaizen management is, why it is applicable to Africa, and why it can provide Africa with a springboard for sustainable economic growth and employment generation.

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Applications of random matrices in physics

Random matrices are widely and successfully used in physics for almost 60-70 years, beginning with the works of Dyson and Wigner. Although it is an old subject, it is constantly developing into new areas of physics and mathematics. It constitutes now a part of the general culture of a theoretical physicist. Mathematical methods inspired by random matrix theory become more powerful, sophisticated and enjoy rapidly growing applications in physics. Recent examples include the calculation of universal correlations in the mesoscopic system, new applications in disordered and quantum chaotic systems, in combinatorial and growth models, as well as the recent breakthrough, due to the matrix models, in two dimensional gravity and string theory and the non-abelian gauge theories. The book consists of the lectures of the leading specialists and covers rather systematically many of these topics.

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An Oral History of the Special Olympics in China ; Vol.2 : The Movement

This book contains the oral histories that were inspired by the work of the Special Olympics in conjunction with the 50th anniversary of its founding. The foreword and prefatory materials provide an overview of the Special Olympics and its growth in the People’s Republic of China.

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Agriculture and Climate Beyond 2015 : A New Perspective on Future Land Use Patterns

Interactions between agriculture, climate and patterns of land use are complex. Major changes in agriculture, and land use patterns are foreseen in the next couple of decades in response to shifts in climate, greenhouse gas management initiatives, population growth and other forces. The book explores key interactions between changes in agriculture, patterns of land use and efforts to reduce greenhouse emissions from agriculture. The volume is based on inter-disciplinary science and policy interactions, exploring the way land use may aid in addressing or be affected by the onset of climate change and alterations in food demand. Future forces shaping land use decisions are examined, and its sensitivity to climate change is highlighted. Patterns of land use and the agricultural role in climate change mitigation are explored. Also, policy and social responses to the new perspectives on future land use patterns are identified. The perspective of the book is beyond the year 2015.

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Advances in statistical methods for the health sciences : Applications to cancer and AIDS studies, genome sequence analysis, and survival analysis

This volume, an outgrowth of an "International Conference on Statistical Methods in Health Sciences," covers a wide range of topics pertaining to new statistical methods and novel applications in the health sciences.

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Advances in Mathematical and Statistical Modeling

Enrique Castillo is a leading figure in several mathematical, statistical, and engineering fields, having contributed seminal work in such areas as statistical modeling, extreme value analysis, multivariate distribution theory, Bayesian networks, neural networks, functional equations, artificial intelligence, linear algebra, optimization methods, numerical methods, reliability engineering, as well as sensitivity analysis and its applications. Organized to honor Castillo's significant contributions, this volume is an outgrowth of the International Conference on Mathematical and Statistical Modeling and covers recent advances in the field. Also presented are applications to safety, reliability and life-testing, financial modeling, quality control, general inference, as well as neural networks and computational techniques.

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Advances in Dynamic Games: Applications to Economics, Finance, Optimization, and Stochastic Control

This book focuses on various aspects of dynamic game theory, presenting state-of-the-art research and serving as a guide to the vitality and growth of the field and its applications. The selected chapters, written by experts in their respective disciplines, are an outgrowth of presentations originally given at the 9th International Symposium of Dynamic Games and Applications. Featured throughout are useful tools for researchers and practitioners who use game theory for modeling in many disciplines.

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