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DNA and RNA origami : methods and protocols
Detials diverse methodological approaches on the assembly and applications of DNA origami assemblies. Chapters guide readers through different synthetic and computational methods, isolation and structural characterization of 2D and 3D DNA origami nanoarchitectures, nanophotonics, drug delivery, biophysics, and synthetic biology.Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.
Dictyostelium discoideum : Methods and protocols
Discusses the latest advancements and techniques used to study Dictyostelium discoideum. The chapters in this book cover topics such as cytokinesis, membrane function and damage, and nutrient/bacterial processing; autophagy activation and function; protein localization, interaction, and activation; cell migration and contact guidance for quantification of cytoskeletal dynamics; and global mutational screening, transcriptome analyses, and proteomics that apply to all stages of the Dictyostelium life cycle and that may generalize to human disease models. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Data Processing in Precise Time and Frequency Applications
The book describes the data processing at various levels: design of the time and frequency references, characterization of the time and frequency references, applications involving precise time and/or frequency references. The metrological properties stability, accuracy and reproducibility are defined and the processes leading to their characterization are shown.
Creep Mechanics ; 2nd ed.
The monograph offers an overview of other experimental investigations in creep mechanics. Rules for specifying irreducible sets of tensor invariants, scalar coefficients in constitutive and evolutional equations, and tensorial interpolation methods are also explained.
Corporate and Investment Banking : Preparing for a Career in Sales, Trading, and Research in Global Markets
Provides unique information to prepare graduates and newly hired corporate and investment banking professionals for a career in the global markets environment of large universal and international investment banks. It shows the interrelationship between the three specific business functions of sales, trading, and research, as well as the interaction with corporate and institutional clients. The book fills a gap in the available literature by linking financial market theory to the practical aspects of day-to-day operations on a trading floor and offers a taxonomy of the current banking business, providing an in-depth analysis of the main market participants in the global markets ecosystem. Engaging the reader with case studies, anecdotes, and industry color, the book addresses the risks and opportunities of the global markets business in today’s global financial markets both from a theoretical and from a practitioner’s perspective and focuses on the most important fixed-income financial instruments from a pricing, risk-management, and client-marketing perspective.
Coping with Uncertainty : Modeling and Policy Issues
Ongoing global changes bring fundamentally new scientific problems requiring new concepts and tools. A key issue concerns a vast variety of practically irreducible uncertainties, which challenge our traditional models and require new concepts and analytical tools. The complexity of new problems does not allow to achieve enough certainty by increasing the resolution of models or by bringing in more links. Hence, new tools for modeling and management of uncertainty are needed, as given in this book.
Contemporary Medical Acupuncture : A Systems Approach
Contemporary Medical Acupuncture aims to bridge the gap between classical acupuncture therapy and contemporary medicine to achieve their ultimate integration. Based on updated reviews and systematic analyses, the meridians are actually systems of physiological and pathological reflexes in the body, and whole body reflex zones is proposed, which may efficiently inherit and clarify the meridian system. The systems methodology, together with the authors’ clinical expertise of 40 years, is applied to raise the reproducibility of effectiveness in treating various indications of acupuncture, especially intractable cases. Outstanding features of the book are its incisive and concrete descriptions about theories and techniques of clinical acupuncture, a novel systems approach, and a great deal of case studies.
Conics and Cubics : A Concrete Introduction to Algebraic Curves
Its focus on curves of degree at most three keeps results tangible and proofs transparent. Theorems follow naturally from high school algebra and two key ideas: homogenous coordinates and intersection multiplicities. By classifying irreducible cubics over the real numbers and proving that their points form Abelian groups, the book gives readers easy access to the study of elliptic curves. It includes a simple proof of Bezout's Theorem on the number of intersections of two curves.The book is a text for a one-semester course on algebraic curves for junior-senior mathematics majors. The only prerequisite is first-year calculus.
Computer Aided Systems Theory – EUROCAST 2007 ; 11th International Conference on Computer Aided Systems Theory, Las Palmas de Gran Canaria, Spain, February 12-16, 2007, Revised Selected Papers
This book presented formal approaches, Computation and Simulation in Modelling Biological Systems, Intelligent Information Processing, Computers in Education, Grid Computing, Applied Formal Verification, Cellular Automata, Computer Vision, Heuristic Problem So.
Computer Aided Systems Theory – EUROCAST 2005 ; 10th International Conference on Computer Aided Systems Theory, Las Palmas de Gran Canaria, Spain, February 7-11, 2005, Revised Selected Papers
The concept of CAST, computer aided systems Theory, was introduced by F. Pichler of Linz in the late 1980s to include those computer theoretical and practical developments used as tools to solve problems in system science. It was considered as the third component (the other two being CAD and CAM) that would provide for a complete picture of the path from computer and systems sciences to practical developments in science and engineering. Selected papers were published as Springer Lecture Notes in Computer Science vols. 410, 585, 763, 1030, 1333, 1728, 2178 and 2809 and in several special issues of Cybernetics and Systems: an lnternational
Materials Syntheses : A Practical Guide
Materials syntheses are generally more complex than syntheses of inorganic or organic compounds, and specific characterization methods play a more important role. Materials synthesis protocols often suffer from unclarities, irreproducibility, lack in detail and lack in standards. The need to change this situation is the main motivation for this book. A number of detailed protocols has been collected, ranging from organic polymers to carbonaceous and ceramic materials, from gels to porous and layered materials and from powders and nanoparticles to films. Preparation methods include intercalation and flux methods, sol-gel processing, templating methods for porous materials, sonochemistry or spray pyrolysis.
Magnetic Functions Beyond the Spin-Hamiltonian
Using the spin-Hamiltonian formalism the magnetic parameters are introduced through the components of the Lambda-tensor involving only the matrix elements of the angular momentum operator. The energy levels for a variety of spins are generated and the modeling of the magnetization, the magnetic susceptibility and the heat capacity is done. Theoretical formulae necessary in performing the energy level calculations for a multi-term system are prepared with the help of the irreducible tensor operator approach. The goal of the programming lies in the fact that the entire relevant matrix elements (electron repulsion, crystal field, spin-orbit interaction, orbital-Zeeman, and spin-Zeeman operators) are evaluated in the basis set of free-atom terms. The modeling of the zero-field splitting is done at three levels of sophistication. The spin-Hamiltonian formalism offers simple formulae for the magnetic parameters by evaluating the matrix elements of the angular momentum operator in the basis set of the crystal-field terms. The magnetic functions for dn complexes are modeled for a wide range of the crystal-field strengths.
Low Thermal Expansion Glass Ceramics
Describes the fundamental principles, the manufacturing process, and applications of low thermal expansion glass ceramics. The composition, structure, and stability of polycrystalline materials having a low thermal expansion are described, and it is shown how low thermal expansion glass ceramics can be manufactured from appropriately chosen glass compositions. Examples illustrate the formation of this type of glass ceramic by utilizing normal production processes together with controlled crystallization. Thus glass ceramics with thermal coefficients of expansion of less than 0.3 x 10(-6)K(-1) can be obtained. Even for the mass production of high-quality cooktop panels (Ceran®., oven windows, and other household appliances a high reproducibility of the properties is achieved. Special glass ceramics (Zerodur®. for technological and scientific applications such as high-precision optics or large astronomical mirrors are likewise discussed. The completely revised edition also features new sections on glass-ceramic applications, with details on their performance, CDC-grinding, and laser gyroscopes containing Zerodur®..
Liver carcinogenesis : Methods and protocols
Discusses the latest advancements in modern methodologies used to study liver carcinogenesis. The first half of this book describes pertinent preclinical models of hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA), established either through orthotopic induction of ectopic implantation. The second half of this book covers a diverse array of techniques applied to characterize the biochemical and cellular composition of hepatic malignancies that operate at the single-cell and histological levels. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Lie Theory Vol.229 : Unitary Representations and Compactifications of Symmetric Spaces
It focuses on two fundamental questions in the theory of semisimple Lie groups: the geometry of Riemannian symmetric spaces and their compactifications; and branching laws for unitary representations, i.e., restricting unitary representations to (typically, but not exclusively, symmetric) subgroups and decomposing the ensuing representations into irreducibles.Ji's introductory chapter motivates the subject of symmetric spaces and their compactifications with carefully selected examples. A discussion of Satake and Furstenberg boundaries and a survey of the geometry of Riemannian symmetric spaces in general provide a good background for the second chapter, namely, the Borel–Ji authoritative treatment of various types of compactifications useful for studying symmetric and locally symmetric spaces. Borel–Ji further examine constructions of Oshima, De Concini, Procesi, and Melrose, which demonstrate the wide applicability of compactification techniques. Kobayashi examines the important subject of branching laws. Important concepts from modern representation theory, such as Harish–Chandra modules, associated varieties, microlocal analysis, derived functor modules, and geometric quantization are introduced. Concrete examples and relevant exercises engage the reader.
Les thérapies ciblées = Targeted therapies
We are at the start of the development of new therapeutic classes, directed against new molecular targets (EGFR, VEGF, IGFR, Rank, etc.) Several diseases such as kidney, colon or breast cancer, GIST, have a natural history now modified thanks to these therapies. This practical book takes stock of the current use of these molecules.
Lactic acid bacteria : Methods and protocols
This updated volume presents experimentation-based approaches to lactic acid bacteria (LAB) research. Split into three parts, the book explores techniques for analyzing lactic acid bacteria metabolism and characteristics, applications for food-related industries, such as yogurt production, beer, and wine making, and functions of LAB in human health. Written for the highly successful Methods in Molecular Biology series, chapters include introduction to their respective topic, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Clinical applications of mass spectrometry in drug analysis : Methods and protocols
This fully updated volume describes methods and protocols for a number of drugs and toxins in a stepwise manner. Exploring the versatility and flexibility of mass spectrometry, the book covers the advantages of this technology, which typically include elimination of the need for special reagents such as antibodies, increased sensitivity and specificity, and multi-component analysis enabling the screening of tens to hundreds of compounds in a single assay run. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls.
Classifications and lists in oral and maxillofacial surgery
Contains a concise collection of the most important oral and maxillofacial surgery classifications and lists. Such classifications help to describe diseases in a comprehensible, measurable, validated and reproducible manner and are the first step towards a systematic approach for treating specific conditions. Elsewhere in this book, lists provide clinical guidance on key subspecialty topics. Using subdivisions such as trauma, head and neck cancer, and orthognathic surgery, this is a succinct and easy-to-use guide for the head and neck clinician.
Cilia : Methods and protocols
Covers the latest advancements in the study of ciliary complexity. Protocols cover genomic, proteomic, imaging, and functional analysis of different ciliated tissues and their wide applicability in cilia biology. Chapters in this book primarily focus on methods to study multiciliated cells, and discuss topics such as SARS-CoV-2 infections of human primary nasal multiciliated epithelial cells; expansion microscopy of ciliary proteins; live-imaging centriole amplification in mouse brain multiciliated cells; biophysical properties of cilia motility; and mucociliary transport device construction. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
