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An Introduction to Copulas

Copulas are functions that join multivariate distribution functions to their one-dimensional margins. The study of copulas and their role in statistics is a new but vigorously growing field. In this book the student or practitioner of statistics and probability will find discussions of the fundamental properties of copulas and some of their primary applications. The applications include the study of dependence and measures of association, and the construction of families of bivariate distributions.

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An Introduction to continuous-time stochastic processes : Theory, models, and applications to finance, biology, and medicine

This book is introduction to the theory of continuous-time stochastic processes. A balance of theory and applications, the work features concrete examples of modeling real-world problems from biology, medicine, industrial applications, finance, and insurance using stochastic methods. No previous knowledge of stochastic processes is required. Key topics covered include: * Interacting particles and agent-based models: from polymers to ants * Population dynamics: from birth and death processes to epidemics * Financial market models: the non-arbitrage principle * Contingent claim valuation models: the risk-neutral valuation theory * Risk analysis in insurance

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An Interactive Multimedia Introduction to Signal Processing

A didactic concept is undertaken for microelectronics, computer technology and communication engineering, which deals with the visualization of signals and processes in addition to graphical programming of signal processing systems. Through the utilization of a professional and globally supported software for metrology and control engineering, DasyLab, useful applications can be developed, modified and optimized. Computer supported processing of real signals is made possible over the sound card and the parallel port. Over two hundred pre-programmed signal engineering systems and design transparencies are provided. Pictures also play a dominant rule in this book: there are numerous introduction-videos, one for every chapter, more than 250 high-quality pictures and - most important – all the "living" experiments and their results are visualized. With this learning system, readers can now make use of "equipment" and software, which was practically unaffordable for individuals in the past. What's more, here is a very new concept for learning Signal Processing, not only from the physically-based scientific fundamentals, but also from the didactic perspective, based on modern results of brain research.

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An Integrated Approach to Software Engineering

An Integrated Approach to Software Engineering introduces software engineering to advanced-level undergraduate and graduate students of computer science. It emphasizes a case-study approach whereby a project is developed through the course of the book, illustrating the different activities of software development. The sequence of chapters is essentially the same as the sequence of activities performed during a typical software project. All activities, including quality assurance and control activities, are described in each chapter as integral activities for that phase of development. Similarly, the author carefully introduces appropriate metrics for controlling and assessing the software process. Chapters in this revised edition, updated for today’s standards, include these new features: Software Process, Requirements Analysis and Specification, Software Architecture, Project Planning, Object Oriented Design, Coding,Testing,

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An Illustrated Guide to Furniture History

Provides upper-level students and instructors with an alternative visual analytical approach to learning about furniture history from Antiquity to Postmodernism. Following an immersive teaching model, it presents a Nine-Step Methodology to help students strengthen their visual literacy and quickly acquire subject area knowledge. Moving chronologically through key periods in furniture history and interior design, such as the Renaissance, the Arts and Crafts Movement, and Modernism, it traverses Europe to America to present a comprehensive foundational guide to the history of furniture design.

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An Energy Analysis of Household Consumption : Changing Patterns of Direct and Indirect Use in India

The book presents a novel socio-economic approach to analysing the - ergy system and energy consumption in India from a household persp- tive. In doing so, it views households as the ultimate end-consumers and estimates and analyses the direct and indirect energy requirements of household consumption, both at an aggregate national level as well as at a disaggregate household level. In addition, the work incorporates two c- cial aspects often ignored by many energy studies that are characteristic of most developing countries, namely the importance of non-commercial sources of biomass energy in the energy systems of these countries, and the enormous diversity and inequity in the patterns of energy access and use across households with different lifestyles and levels of well being.

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An ecological and societal approach to biological control

Biological control is among the most promising methods for control of pests (including vectors), diseases and weeds. In this book ecological and societal aspects are for the first time treated together. In an ecological approach the aim is to evaluate the significance of certain biological properties like biodiversity and natural habitats. Also, it is important to see biological control from an organic (or ecological) farming point of view. In a societal approach terms like ‘consumer’s attitude’, ‘risk perception’, ‘learning and education’ and ‘value triangle’ are recognised as significant for biological production and human welfare.

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Amino acid biosynthesis : Pathways, regulation and metabolic engineering

Amino Acids Biosynthesis presents the current knowledge of fundamental as well as applied microbiology of amino acids. Topics discussed are the amino acid biosynthetic pathways, their genetic and biochemical regulation, transport of amino acids and genomics of producing microorganisms. The characterization of the control mechanisms of amino acid biosynthesis has revealed insights into principles of genetic and biochemical regulation, such as transcriptional regulators and a new class of regulatory elements, the riboswitch. The volume further deals with the metabolic engineering of microorganisms for the biotechnological production of amino acids for use as pharmaceuticals and, particularly, as food and feed additives.

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Ambisonics : A Practical 3D Audio Theory for Recording, Studio Production, Sound Reinforcement, and Virtual Reality

Provides a concise explanation of the fundamentals and background of the surround sound recording and playback technology Ambisonics. It equips readers with the psychoacoustical, signal processing, acoustical, and mathematical knowledge needed to understand the inner workings of modern processing utilities, special equipment for recording, manipulation, and reproduction in the higher-order Ambisonic format. The book comes with various practical examples based on free software tools and open scientific data for reproducible research. The book includes an extensive mathematical appendix. The book offers readers a deeper understanding of Ambisonic technologies, and will especially benefit scientists, audio-system and audio-recording engineers.

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Ambient Intelligence ; European Conference, AmI 2007, Darmstadt, Germany, November 7-10, 2007, Proceedings

This book presented sections on mobility and sensing, applications of AmI, activity and location sensing, AmI and artificial intelligence, AmI middleware and infrastructure, and interaction with the environment. The book is rounded off by a section on case studies and lessons learned, presenting a high level selection of current research reports and papers that reflect the most important activities of current ambient intelligence research.

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Ambient intelligence : A novel paradigm

Ambient Intelligence (AmI) is an integrating technology for supporting a pervasive and transparent infrastructure for implementing smart environments. Such technology is used to enable environments for detecting events and behaviors of people and for responding in a contextually relevant fashion. AmI proposes a multi-disciplinary approach for enhancing human machine interaction. The authors start with a description of the iDorm as an example of a smart environment conforming to the AmI paradigm, and introduces computer vision as an important component of the system. Other computer vision examples describe visual monitoring for the elderly, classic and novel surveillance techniques using clusters of cameras installed in indoor and outdoor application domains, and the monitoring of public spaces. Face and speech recognition systems are also covered as well as enhanced LEGO blocks for novel educational purposes. The book closes with a provocative chapter on how a cybernetic system can be designed as the backbone of a human machine interaction.

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Amartya Sens Capability Approach: Theoretical Insights and Empirical Applications

Kuklys examines how Nobel Prize-winning economist Amartya Sen’s approach to welfare measurement can be put in practice for poverty and inequality measurement in affluent societies such as the UK. Sen argues that an individual’s welfare should not be measured in terms of her income, but in terms what she can actually do or be, her capabilities. In Chapters 1 and 2, Kuklys describes the capability approach from a standard welfare economic point of view and provides a comprehensive literature review of the empirical applications in this area of research. In the remaining chapters, novel econometric techniques are employed to operationalise the concepts of functionings and capability to investigate inequality and poverty in terms of capability in the UK. Kuklys finds that capability measurement is always a useful complement to traditional monetary analysis, and particularly so in the case of capability-deprived disabled individuals.

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Alzheimer's disease : Peptide vaccine and immunotherapy

Peptide vaccines and immunotherapies against aggregating proteins involved in the pathogenesis and progression of Alzheimer's disease (AD) the ẞ-amyloid peptide (Aẞ) and tau are promising therapeutic avenues against AD. Two decades of effort has led to the controversial United States Food and Drug Administration (FDA) approval of the monoclonal antibody Aducamumab (Aduhelm), which has subsequentially sparked the revival and expedited review of promising monoclonal antibody immunotherapies that target Aẞ.

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Alzheimer's Disease

Alzheimer is a disease which has not a cure yet, and about 10% of the population worldwide will suffer from it. However younger people may also develop this disease mainly at 45 years old mainly women who has double the rate of incidence since 1 if five women will certainly develop it. Therefore the goal of our research is to study first of all the history of such popular disease and its risk factors and current therapies or iagnostic tools and more important we will introduce a test which was discovered few months ago to predict the risk of developing Alzheimer few decades before it occurs and we will apply it in our laboratories in Syria as well. Beside this preventive test we will add also a very important diet to follow up by people who has a family history.

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Alzheimers Disease

Alzheimer’s disease (AD) is a neurodegenerative disease that robs the minds of our elderly population. Approximately one in every eight adults over the age of 65 and nearly half of those over 85 are afflicted with this disease. The aging population in developed societies will impose an ever increasing socioeconomic threat in the future. Current medicines for AD patients are mainly symptomatic treatments and a huge unmet medical need exists to slow the progression of this disease. A great deal of research has been dedicated to understanding the pathogenesis of AD from which comes many ideas for intervening with its progression. Some of these ideas have been fast-tracked to clinical trials due to the availability of medicines with proven clinical efficacies for other diseases (e.g. atorvastatin, simvastatin, rosiglitazone and clioquinol) while others represent novel chemical entities (e.g. glycogen synthase kinase-3 inhibitors).

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Alternatives to Animal Testing : Proceedings of Asian Congress 2016

This book presents recent advances in the pure sciences that are of significance in the quest for alternatives to the use of animals in research and describes a variety of practical applications of the three key guiding principles for the more ethical use of animals in experiments – replacement, reduction, and refinement, collectively known as the 3Rs. Important examples from across the world of implementation of the 3Rs in the testing of cosmetics, chemicals, pesticides, and biologics, including vaccines, are described, with additional information on relevant regulations. The coverage also encompasses emerging approaches to alternative tests and the 3Rs.

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Alternatives Considered But Not Disclosed : The Ambiguous Role of PowerPoint in Cross-Project Learning

This study investigates the role of PowerPoint in organizational communication, particularly in terms of a functional dilemma between its application for documentation as opposed to presentation purposes. The theoretical part of the analysis combines insights from both organizational communication studies (J. R. Taylor et al.) and social systems theory (N. Luhmann et al.). The empirical analysis shows that PowerPoint documents created for cross-project learning purposes contribute to an invisibilization rather than a visibilization of decision processes and their contingency.

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Alternative Splicing and Disease

Splicing of primary RNA transcript, i.e. removal of introns and joining of exons to produce mature mRNAs competent for translation into proteins, is a quasi-systematic step of gene expression in higher organisms. However, this process is not unequivocal but can follow alternate pathways. Alternative splicing of a given transcript can therefore yield several distinct mRNAs encoding as many different proteins. Its full biological significance has not been appreciated until it was recognized that alternative splicing is so general as to affect about 75% of all human genes. Therefore, alternative splicing not only vastly increases protein diversity but also offers numerous opportunities for aberrant splicing events with pathological consequences.

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Alternative pseudodifferential analysis : With an application to modular forms

This volume introduces an entirely new pseudodifferential analysis on the line, the opposition of which to the usual (Weyl-type) analysis can be said to reflect that, in representation theory, between the representations from the discrete and from the (full, non-unitary) series, or that between modular forms of the holomorphic and substitute for the usual Moyal-type brackets. This pseudodifferential analysis relies on the one-dimensional case of the recently introduced anaplectic representation and analysis, a competitor of the metaplectic representation and usual analysis.

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Alternative Education : Global Perspectives Relevant to the Asia-Pacific Region

Alternative streams of education have been and remain an important but difficult theme for teachers, parents, policy-makers, and scholars. By focusing on case studies of six countries (Bolivia, Thailand, Australia, USA, The Netherlands, and Denmark), and by comprehensively analysing these by means of international comparative methodologies, the author approaches the nuts and bolts issues of alternative and mainstream education systems. The case studies include Charter Schools in the USA and Waldorf Schools in Australia. The study presents not only an insightful analysis of alternative forms of education with regard to actual issues in societies and also legal and administrative features of education. It provides insights into the kind of school development that could be appropriate in the 21st century and the types of educational communities we should seek to create in the age of globalisation.

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