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Drugs, the brain, and behavior : The pharmacology of therapeutics and drug use disorders
Provides a comprehensive overview of the brain and explores the clinical and pharmacological issues surrounding drug abuse and dependence. Dr Brick provides definitions, historic discoveries about the nervous system, and original, eye-catching illustrations to discuss the brain/behavior relationship, basic neuroanatomy, neurophysiology, and the mechanistic actions of mood-altering drugs. Topics include: how psychoactive drugs affect cognition, behavior, and emotion; the brain/behavior relationship; the specific effects of major addictive and psychoactive drug groups; new definitions and thinking about abuse and dependence; and the medical uses of drugs, such as cannabinoids. A new chapter on biobehavioral markers explores how markers can guide the clinician in the diagnosis of some disorders. This book offers a quick reference guide which uses a balance of instruction, illustrations, tables, and formulas, that will give you a broad, lasting introduction to this intriguing subject.
Drugs quality control (theoretical foundation and practical application) : The coursebook
Presents the basics of drugs quality control in accordance with regulatory documents (pharmacopoeia of Europe, USA, Japan, Russia) and new data from current scientific periodicals, monographs The features of the physical, spectral and chemical quality control of medicines according to the indicators «identification», «tests» and «assay» are described in detail. Part II presents a workbook, which includes questions for the self-control of the material studied and tasks for a laboratory workshop. The Course book contains reference material and samples of pharmacopoeial articles. The Course book is designed for students of the specialty «Pharmacy».
Drug interactions in infectious diseases : Mechanisms and models of drug interactions
Provides a comprehensive review of basic clinical pharmacology with a focus on metabolism and transporter-mediated drug interactions. The chapters address materials that cannot be retrieved easily in the medical literature, including materials focused on the complex interrelationship of acute infection, inflammation, and the risk of drug interactions in the Drug-Cytokine chapter. The Food-Drug and Herb-Drug interactions chapters remain definitive resources. A new chapter on in vitro modeling of drug interactions is included along with updates on design and data analysis of clinical drug interaction studies. Authoritative discussion of models for regulatory decision-making on drug-drug interactions provides the necessary framework to aid antimicrobial drug development. This concise review of the mechanisms and models of drug interactions provides important insights to health care practitioners as well as scientists in drug development
Drug delivery trends ; Vol. 3 : Expectations and realities of multifunctional drug delivery systems
Examines a drift in the pharmaceutical field across the wide range of dosage forms, drug delivery systems (micro and nanoparticulate), at the regulatory front and on new types of therapies in the market. This book covers the challenges on drug delivery systems in terms of preclinical and current ways of determining quality and the options to solve the challenges associated with this. Most small-medium scale industries and academics struggle with initial regulatory challenges so a detailed discussion on regulatory trend covers the necessary basic understanding of regulatory procedures and provides the required guidance.
Drug Addiction : From Basic Research to Therapy
Drug Addiction: From Basic Research to Therapy provides a comprehensive overview of physiological, biochemical, genetic and behavioral pathways underlying drug addiction. Focusing on fundamental neurophysiological processes that overlap between drug addiction and other CNS disorders, this volume covers the translation of basic research into novel therapies, not only of drug addiction but a spectrum of related CNS disorders, including pain. Chapters are written by leading scientists with widely ranging expertise in synthetic and computational chemistry, molecular biology, genetics, neurosciences, drug discovery and development, drug targeting, and quantitative therapeutics, providing an unprecedented overview of a complex field of high societal signficance.
Drawing with a tablet : Easy techniques for mastering digital drawing on location
learn step by step how to create amazing drawings while on the go. Shows sketchers how to take their digital drawing to the next level. Whether you are new to sketching or wish to try the latest technology, this useful guide shares expert tips and techniques for drawing on a tablet. With a focus on using the ProCreate tool, but with information that is relevant to other digital platforms, you will start with the basics, such as opening your file, choosing your resolution, determining your palette, and how to simplify your tools by creating a preferred set of brushes.Covers using layers and groups of layers, and shows you how to create a sketch from start to finish.
Drawing Ideas
Focuses on the three key types of drawing, explanatory sketches, notational sketches and visual narratives that help designers think through and communicate their ideas. Through these three fundamentals, Drawing Ideas provides a thorough course in creating clear graphic layouts and diagrams, including expressive human forms, thumbnailing a process, adding effective colour and text and more. In addition, a drawing boot camp provides a refesher course in accurately drawing geometric forms. By getting back to the basics, readers will not only benefit from updated freehand drawing skills, but will also succeed in presenting and explaining their drawings and designs to others.
Drawing for Interior Design ; 2nd ed.
Covers all stages of visual presentation as part of the interior design process, from the most basic initial sketches to fully developed computer-generated visualizations. Following a brief introduction four chapters take the reader through the design process, from the basics to conception, presentation and production. This second edition includes more practical advice on techniques, more case studies, step-by-step sequences and updated examples. With a varied and comprehensive range of images, this book is an invaluable, inspirational and practical resource for interior design students.
Doppler Ultrasound in Obstetrics and Gynecology
Doppler Ultrasound in Obstetrics & Gynecology encompasses the full spectrum of clinical applications of Doppler ultrasound for the practicing obstetrician-gynecologist, including the latest advances in 3D and color Doppler and the newest techniques in 4D fetal echocardiography. Written by preeminent experts in the field, the book covers the basic and physical principles of Doppler ultrasound; the use of Doppler for fetal examination, including fetal cerebral circulation; Doppler echocardiography of the fetal heart; and the use of Doppler for postdated pregnancy and in cases of multiple gestation. Chapters on the use of Doppler for gynecologic investigation include ultrasound in ectopic pregnancy, for infertility, for benign disorders and for gynecologic malignancies.
Doormaking : Materials, Techniques, and Projects for Building Your First Door
Starts first by addressing the fundamentals: the basics of good design and proper construction technique, the pros-and-cons of common materials including wood and sheet goods, interior and exterior finishes, hardware and the fine points of hanging doors. Once those key elements are covered, it offers project chapters that walk the reader step-by-step through the construction of eight essential doors, explaining design and material choices in specific contexts, tool options and other considerations. The first four projects are easly accessible to a beginner while the the remaining projects offer up some more challenging details for the intermediate woodworker. Also included are sidebars containing amusing anecdotes and mistake stories each delivering tips as well as details for hanging a door and an inspiring gallery of doors that are sure to inspire.
Don’t Panic with Mechanics! : Fun and success in the "loser discipline" of engineering studies!
The ultimate companion in the classical horror discipline of engineering science! Contents of the book are the basics of mechanics as treated in engineering and physical sciences: Statics, Elastostatics, Kinematics & Kinetics in unconventional, humorous presentation with many cartoons, funny explanations and a chapter containing several exercises with detailed solutions.
DOM Scripting : Web Design with JavaScript and the Document Object Model
There are three main technologies married together to create usable, standards-compliant web designs: XHTML for data structure, Cascading Style Sheets for styling your data, and JavaScript for adding dynamic effects and manipulating structure on the fly using the Document Object Model. This book is about the latter of the three. DOM Scripting: Web Design with JavaScript and the Document Object Model gives you everything you need to start using JavaScript and the Document Object Model to enhance your web pages with client-side dynamic effects. Jeremy Keith starts off by giving you a basic crash course in JavaScript and the DOM, then moves on to provide you with several real-world examples built up from scratch, including dynamic image galleries and dynamic menus. Then, he shows you how to manipulate web page style using the CSS DOM, and create markup on the fly.
DNA Methylation : Development, Genetic Disease and Cancer
It has become apparent that the genomes of many organisms are characterized by unique patterns of DNA methylation which can differ from genome segment to genome segment and cell type to cell type. These patterns can be instrumental in determining cell type and function. Thus, it is not surprising that studies on the role of DNA methylation now occupy center stage in many fields of biology and medicine such as developmental biology, genetic imprinting, genetic disease, tumor biology, gene therapy, cloning of organisms and others. Once again, basic research in molecular biology has provided the essential foundation for investigations of biomedical problems.
DNA Methylation : Basic Mechanisms
The structural and functional importance of the correct patterns of DNA methylation in all parts of a mammalian genome is not well understood. The stability, inheritability, and developmental flexibility of these patterns point to a major role that these patterns appear to play in determining structure and function of the genome.
DNA manipulation and analysis
Details technologies on recombinant DNA and nucleic acid manipulation that underpin much of the biological sciences and instructions on how to conduct them successfully. Chapters guide the reader through the basics of oligonucleotide synthesis and DNA sequencing; recombinant DNA plasmid work; cell-free experiments and the latest developments in CRISPR approaches to genome modification.
Distributed Embedded Control Systems : Improving Dependability with Coherent Design
Distributed Embedded Control Systems handles the domains encountered when designing a distributed embedded computer control system as an integrated whole. First to be discussed are some basic issues about real-time systems and their properties, specifically safety. Then, system and hardware architectures are dealt.
Distributed Computing and Internet Technology ; 4th International conference, ICDCIT 2007, Bangalore, India, December, 17-20, 2007, Proceedings
The book is covering a range of issues from basic technology, through services and engineering, to applications, from development issues, through middleware support, to actual delivery of e-Society services.
Disorders of the Respiratory Tract : Common Challenges in Primary Care
In Disorders of the Respiratory Tract: the author covers the range of knowledge needed to provide excellent care for patients with respiratory disease, from the basics of pulmonary function testing to understanding and caring for common respiratory illnesses, including chronic obstructive pulmonary disease, asthma, allergic rhinitis, and pneumonia. Less common illnesses.
Discovering Mathematics with Magma : Reducing the Abstract to the Concrete
This volume celebrates the first decade of the Computer Algebra system Magma. With a design based on the ontology and semantics of algebra, Magma enables users to rapidly formulate and perform calculations in the more abstract parts of mathematics. The book range over much of Magma's coverage of algorithmic algebra: from number theory and algebraic geometry, via representation theory and group theory to some branches of discrete mathematics and graph theory. A basic introduction to the Magma language is given in an appendix. The book is simultaneously an invitation to learn a new programming language in the context of contemporary research problems, and an exposition of the types of problem that can be investigated using computational algebra.
Discoveries in Photosynthesis
Conceived of as a way of summarizing the history of research advances in photosynthesis as of millennium 2000, the book evolved into a majestic and encyclopedic saga involving all of the basic sciences. This book is meant not only for the researchers and graduate students, but also for advanced undergraduates in Plant Biology, Microbiology, Cell Biology, Biochemistry, Biophysics and History of Science.
