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Handbook of Radiopharmaceuticals : Methodology and Applications ; 2nd ed.

A comprehensive review of the field, presenting up-to-date coverage of central topics such as radionuclide production, synthetic methodology, radiopharmaceutical development and regulations, and a wide range of practical applications. A valuable reference work for those new to the Radiopharmaceutical Sciences and experienced professionals alike, this volume explores the latest concepts and issues involving both targeted diagnostic and therapeutic radiopharmaceuticals. Contributions from a team of experts from across sub-disciplines provide readers with an immersive examination of radiochemistry, nuclear medicine, molecular imaging, and more. Features extensive new and revised content throughout Covers key areas of application for diagnosis and therapy in oncology, neurology, and cardiology Emphasizes the multidisciplinary nature of Radiopharmaceutical Sciences Discusses how drug companies are using modern radiopharmaceutical imaging techniques to support drug discovery Examines current and emerging applications of Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT)

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Forensic neuropathology and associated neurology

Incorporating the most recent literature and state-of-the-art methods, this practical work and atlas covers the entire domain of neuropathology for forensic pathologists as well as for specialists in associated fields. Its concise, direct style provides the reader with succinct and easy-to-find answers to forensic, pathological, pathophysiological, biomechanical, and molecular biology problems.

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Feldman and Pike's vitamin D; Vol. 2 : Health, disease and therapeutics

Covers the evidence for new roles of vitamin D, ranging from organ transplantation to cancer, diabetes, inflammatory bowel disease, multiple sclerosis, and renal disease. The coverage is appropriately broad, drawing on aspects of internal medicine, pediatrics, nutrition, orthopedics, oncology, neurology, obstetrics and gynecology, and immunology, as well as, new areas for vitamin D including sports medicine, opthalmology, veterinary medicine and ICU care – including COVID-19. Clinical researchers will gain a strong understanding of the molecular basis for a particular disease and better understand future directions for research in this still-growing field.

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Evoked Spinal Cord Potentials : An illustrated Guide to Physiology, Pharmocology, and Recording Techniques

This book surveys the neurophysiological and neuropharmacological bases of evoked SCPs with reference to animal studies and to recording those potentials mainly from the spinal epidural space. Generous use of illustrations promotes understanding of the neurophysiological and neuropharmacological backgrounds of monitoring spinal cord functions, and case studies provide additional insight into the monitoring and diagnosis of spinal cord dysfunction and disease.

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Evidence-based positron emission tomography : Summary of recent meta-analyses on PET

This book summarizes the findings of recent evidence-based articles (meta-analyses) on the use of positron emission tomography (PET) for various clinical indications. It is divided into five main sections, starting with an introduction to PET and meta-analysis.

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Evidence based practice in Neuro-oncology

This book provides evidence-based management in neuro-oncology covering all aspects such as pathology, radiology, surgery, radiation, and chemotherapy.The field of neuro-oncology is rapidly evolving and new evidence is coming out every day towards the optimal management of brain tumors. This necessitates a requirement of a complete guide that shall provide an evidence-based and personalized approach towards dealing with patients. This book also covers recent advances in personalized treatment formed through the relevant basis of anatomy, imaging, radiology, surgical, radiation and systemic treatment of brain and spinal tumors. In addition it also covers the , practical aspects of the planning of the Gamma knife and other radio surgical aspects.

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Évaluation des troubles neuropsychologiques en vie quotidienne = Assessment of neuropsychological disorders in daily life

Neurological diseases such as stroke, head trauma, Alzheimer's disease pose a public health problem. They affect all ages, from children to the elderly. They affect the possibilities of autonomy in daily life, the possibilities of social or professional integration. In these pathologies, neuropsychological disorders: disorders of language, memory, attention, etc., are the source of crucial difficulties. Cognitive tests performed by psychologists are essential for their diagnosis, but do not on their own make it possible to prejudge the difficulties encountered by people in their everyday life. This book presents an original approach to neuropsychological disorders, by describing specific assessments describing difficulties in daily life, in order to better understand them and to quantify their impact. The second part of the book develops the consequences in clinical practice in particular populations - children and the elderly - or the social objective of the evaluation, in particular school integration, professional integration and driving. Finally, the relevance of these assessments in the context of recent laws on disabled people as well as the development of compensation for bodily injury after an accident are also discussed.

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Essential Practice Guidelines in Primary Care

This book is an excellent summary of the most important evidence-based, nationally recognized, clinical guidelines, with aim to improve the quality of medical care. It represents understandable, useful, easy to implement, one source for questions arises that is best answered by an existing clinical guideline. Together with electronic (PDA) version, should facilitate the implementation of nationally recognized clinical guidelines by primary care physicians.

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Encyclopedia of Pain

The Encyclopedia of Pain includes more than 3,000 entries and provides clear, detailed and up-to-date coverage of the current state of research, and treatment of pain. In addition, detailed essays provide in-depth information on all aspects of nociception and pain, including substrates, causes, pathophysiology, symptoms and signs, diagnoses and treatment. A thousand color figures enhance understanding of this too-little-understood topic.

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Electronic engineering for neuromedicine

Advances in electronics have revolutionized diagnostic tools and created mobile medicine, touch-sensitive prosthetics, remote surgery, and artificial organs such as hearts, retinas, and bionic skins. This reference text shows the number of ways in which electronic engineering feeds into neuromedicine namely: the modelling and simulation of the brain, providing access to the brain, analysis of the signals and activities of the brain and influencing the function of the brain for therapeutic purposes. The areas of electronic engineering considered are electronic circuits, spectral analysis, filtering of signals, electromagnetic fields and wave propagation. The book is a valuable source to medical students and practitioners as well as electronic engineering and physics students and graduates.

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Electrical Diseases of the Heart : Genetics, Mechanisms, Treatment, Prevention

Electrical Diseases of the Heart is a thorough clinical reference on the current status of cardiac electrophysiological disease,emphasizing common and diverse clinical features. The latest developments in the field of experimental and clinical cardiac electrophysiology, genetics, pharmacology, and interventional therapies of various clinical arrhythmogenic entities are featured and discussed in terms of recent advances in basic and clinical science.

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Diseases of the Brain, Head and Neck, Spine 2020–2023 : Diagnostic Imaging

This book offers an essential overview of brain, head and neck, and spine imaging. Over the last few years, there have been considerable advances in this area, driven by both clinical and technological developments.

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Diagnostic Criteria in Neurology

The criteria cover a wide spectrum of neurological conditions whose diagnosis does not depend solely on histopathology (e.g., brain tumors), including cerebrovascular diseases, dementias and behavioral disorders, demyelinating disorders, and disorders of consciousness and brain death.

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Coordination : Neural, Behavioral and Social Dynamics

One of the most striking features of Coordination Dynamics is its interdisciplinary character. The problems we are trying to solve in this field range from behavioral phenomena of interlimb coordination and coordination between stimuli and movements (perception-action tasks) through neural activation patterns that can be observed during these tasks to clinical applications and social behavior. It is not surprising that close collaboration among scientists from different fields as psychology, kinesiology, neurology and even physics are imperative to deal with the enormous difficulties we are facing when we try to understand a system as complex as the human brain.

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Conscious in a Vegetative State? A Critique of the PVS Concept

This book traces the origins of prevailing perceptions about PVS and submits these to critical examination. In doing this it comes to the conclusion that inadequate attention has been paid to acknowledging what is not known about affected individuals and that assumptions have consistently come to be traded as facts. Re-examination of the basis of the PVS and the adoption of a more scientific approach is long overdue and is owed to the community at large which has generally been provided by many medical practitioners with a 'dumbed-down' account of the condition.

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Cognitive Behavioral Treatment of Insomnia : A Session-by-Session Guide

Cognitive behavior therapy which has been adapted to treat so many problems, has also brought data-driven and data-yielding treatment to insomnia. Focusing on this evidence-based modality, Cognitive Behavioral Treatment of Insomnia is a much-needed treatment manual that provides clinicians with the why’s and how’s of this approach in concise and practical terms.

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Clinical PET and PET

A practical manual covering the full spectrum of PET and PET/CT imaging, now in common clinical practice, this book includes images of normal variants, artifacts, and pathologic conditions. Indications for and the relative clinical value of PET in the armamentarium of diagnostic medical imaging are reviewed. The information in the book is organized to be brief, concise, easy-to-understand and readily accessed.

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Clinical Pathways in Stroke Rehabilitation : Evidence-based Clinical Practice Recommendations

This book focuses on practical clinical problems that are frequently encountered in stroke rehabilitation. Consequences of diseases, e.g. impairments and activity limitations, are addressed in rehabilitation with the overall goal to reduce disability and promote participation.

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Magnetic Resonance of Myelination and Myelin Disorders

The book has been extensively revised and expanded to do justice to the rapid advances in MR technology, molecular biochemistry, and genetics and the discovery of new disease entities with prominent white matter involvement. Forty chapters have been added, and the number of illustrations has risen considerably. The ability to confirm the presence of genetic alterations in a number of disorders allows more advantageous presentation of the phenotypic variation as expressed in differ.

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Machine learning for brain disorders

Organized into five parts. Part One presents the fundamentals of ML. Part Two looks at the main types of data used to characterize brain disorders, including clinical assessments, neuroimaging, electro- and magnetoencephalography, genetics and omics data, electronic health records, mobile devices, connected objects and sensors. Part Three covers the core methodologies of ML in brain disorders and the latest techniques used to study them. Part Four is dedicated to validation and datasets, and Part Five discusses applications of ML to various neurological and psychiatric disorders.

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