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EAES Guidelines for Endoscopic Surgery : Twelve Years Evidence-Based Surgery in Europe
This work allows readers to gain an overview of cutting edge surgical research. All recommendations describe exactly the proven benefit of each surgical procedure and technique. Most guidelines contain key statements. All chapters follow a structured format to allow quick identification of all recommendations. In summary, this work provides a perfect overview of the achievements in laparoscopic surgery throughout the last decade.
Dynamical Entropy in Operator Algebras
The book including quantum dynamical systems and applications of operator algebras and ergodic theory. Although the authors assume a basic knowledge of operator algebras, they give precise definitions of the notions and in most cases complete proofs of the results which are used.
Dynamic Population Models
The book is well organized and clearly written so that it is accessible to those with only a minimal knowledge of calculus. It begins with a review of fixed rate population models, from the basic life table to multistate stable populations. The process of convergence to stability is described, and the regularities underlying change in the size and composition of any population are explored. Techniques for estimating rates from multistate population distributions are presented, and new multi-age, multistate dynamic models are developed.
Dynamic General Equilibrium Modelling : Computational Methods and Applications
Modern business cycle theory and growth theory uses stochastic dynamic general equilibrium models. Many mathematical tools are needed to solve these models. The book presents various methods for computing the dynamics of general equilibrium models. In part I, the representative-agent stochastic growth model is solved with the help of value function iteration, linear and linear quadratic approximation methods, parameterised expectations and projection methods. In order to apply these methods, fundamentals from numerical analysis are reviewed in detail. Part II discusses methods for solving heterogeneous-agent economies. In such economies, the distribution of the individual state variables is endogenous. This part of the book also serves as an introduction to the modern theory of distribution economics. Applications include the dynamics of the income distribution over the business cycle or the overlapping-generations model.
Dual Income Tax : A Proposal for Reforming Corporate and Personal Income Tax in Germany
In its Annual Report 2003/2004, the German Council of Economic Experts launched a dual income tax as an option for a fundamental tax reform in Germany. In February 2005, the German government appointed the Council to prepare a detailed report on economic effects of a business tax reform, with special emphasis on a dual income tax. With regard to the latter, conceptual problems of tax law and of tax administration were to be addressed as well as possible transitional problems when implementing a dual income tax. This book presents an English version of the original report completed in April 2006.
Drug target selection and validation
Focuses on the computational aspects of early drug discovery, drug target identification, and validation. It revises current classical paradigms in target and phenotypic-based drug design with still ingrained approximations and concepts and discusses the research in the new network approach concept that include kinetic selectivity and metabolic analysis. Many often-overlooked approximations and concepts in drug discovery are fully covered. Drug Target Selection and Validation includes both introductory sections and research-based sections to be of use to both students and research scientists in drug discovery, design, kinetics and metabolic analysis. Pharmaceutical scientists, pharmaceutics, drug developers, pharmacologists, biomedical researchers in computer science, medicinal chemists, and precision medicine developers benefit from the information provided. The book concludes with a chapter on chemical and structural databases.
Drug discovery and GBCR – Related CNS Disorders
Neurodegenerative diseases are a large group of neurological disorders with diverse etiological and pathological phenomena. However, current therapeutics rely mostly on symptomatic relief while failing to target the underlying disease pathobiology. G-protein-coupled receptors (GPCRs) are one of the most frequently targeted receptors for developing novel therapeutics for central nervous system (CNS) disorders. Many currently available antipsychotic therapeutics also act as either antagonists or agonists of different GPCRs. Therefore, GPCR-based drug development is spreading widely to regulate neurodegeneration and associated cognitive deficits through the modulation of canonical and noncanonical signals.
Drug Addiction : From Basic Research to Therapy
Drug Addiction: From Basic Research to Therapy provides a comprehensive overview of physiological, biochemical, genetic and behavioral pathways underlying drug addiction. Focusing on fundamental neurophysiological processes that overlap between drug addiction and other CNS disorders, this volume covers the translation of basic research into novel therapies, not only of drug addiction but a spectrum of related CNS disorders, including pain. Chapters are written by leading scientists with widely ranging expertise in synthetic and computational chemistry, molecular biology, genetics, neurosciences, drug discovery and development, drug targeting, and quantitative therapeutics, providing an unprecedented overview of a complex field of high societal signficance.
Drop acid
Our most respected scientific literature is bursting with evidence that elevated uric acid levels lie at the root of many pervasive health conditions, but mainstream medicine for the most part remains unaware of this connection. This is especially alarming because many people don’t know they are suffering from sky-high levels, putting them at risk for developing or exacerbating potentially life-threatening illnesses.
Drawn to Design : Analyzing Architecture Through Freehand Drawing
A guide for students and teachers to understand the need for, the role of and the methods and techniques of freehand analytical sketching in architecture. The presentation focuses on drawing as an approach to and phase of architectural design. The conceptual goal of this approach is to use drawing not as illustration or depiction, but as exploration. The first part of the book discusses underlying concepts of freehand sketching in design education and practice as a complement to digital technologies. The main component is a series of chapters that constitute a typology of fundamental issues in architecture and urban design; for instance, issues of "façade" are illustrated with sketch diagrams that show how façades can be explored and sketched through a series of specific questions and step-by-step procedures.
Drawn to Design : Analyzing Architecture Through Freehand Drawing
A guide for students and teachers to understand the need for, the role of and the methods and techniques of freehand analytical sketching in architecture. The presentation focuses on drawing as an approach to and phase of architectural design. The conceptual goal of this approach is to use drawing not as illustration or depiction, but exploration. The first part of the book discusses underlying concepts of freehand sketching in design education and practice as a compliment to digital technologies. The main component is a series of chapters that constitute a typology of fundamental issues in architecture and urban design; for instance, issues of "facade" are illustrated with sketch diagrams that show how facades can be explored and sketched through a series of specific questions and step-by-step procedures.
Drawing imagining building : Embodiment in architectural design practices
Drawing Imagining Building focuses on the history of hand-drawing practices to capture some of the most crucial and overlooked parts of the process. Using 80 black and white images to illustrate the examples, it examines architectural drawing practices to elucidate the ways drawing advances the architect’s imagination.
Do Exclusionary Rules Ensure a Fair Trial? : A Comparative Perspective on Evidentiary Rules
This publication discusses exclusionary rules in different criminal justice systems. It is based on the findings of a research project in comparative law with a focus on the question of whether or not a fair trial can be secured through evidence exclusion. Part I explains the legal framework in which exclusionary rules function in six legal systems: Germany, Switzerland, People’s Republic of China, Taiwan, Singapore, and the United States. Part II is dedicated to selected issues identified as crucial for the assessment of exclusionary rules. These chapters highlight the delicate balance of interests required in the exclusion of potentially relevant information from a criminal trial and discusses possible approaches to alleviate the legal hurdles involved.
Distributed computing and networking ; 9th International Conference, ICDCN 2008, Kolkata, India, January 5-8, 2008. Proceedings
This book constitutes the refereed proceedings of the 9th International Conference on Distributed Computing and Networking, ICDCN 2008 - formerly known as IWDC (International Workshop on Distributed Computing) - held in Kolkata, India, in January 2008.
Disruptive trends in automation technology
The industrial sector is being transformed by the convergence of information technology and operational technology. The latter is another name for automation technology and covers established systems such as supervisory control and data acquisition (SCADA), programmable logic controllers (PLC), fieldbuses, and automation and control systems. As this technology is connected to the Internet and 5G networks, some monitoring, control, and analytic functionalities are deployed to the edge or cloud, and researchers are challenged to ensure the security, dependability, real-time performance, and maintainability of the resulting systems. The big data that is accessible from these systems create opportunities for artificial intelligence applications that can further disrupt the established practices in the automation domain.
Directions in strong motion instrumentation ; Proceedings of the NATO SFP Workshop on Future Directions in Instrumentation for Strong Motion and Engineering Seismology, Kusadasi, Izmir, May 17-21, 2004
This book, which contains papers by invited authorities, represents a unique interaction between seismologists and earthquake engineers who examine issues of mutual concern in an overlapping area of major interest. The papers have been grouped around three major areas. -Seismic Hazard and Extreme Motions -Engineering Uses of Strong Motion Seismograms -Arrays and Observations.
Dilated Cardiomyopathy : From Genetics to Clinical Management
This book presents a comprehensive overview of dilated cardiomyopathy, providing readers with practical guidelines for its clinical management. The first part of the book analyzes in detail the disease’s pathophysiology, its diagnostic work up as well as the prognostic stratification, and illustrates the role of genetics and gene-environment interaction. The second part presents current and future treatment options, highlighting the importance of long-term and individualized treatments and follow-up.
Digital Libraries : Achievements, Challenges and Opportunities ; 9th International Conference on Asian Digial Libraries, ICADL 2006, Kyoto, Japan, November 27-30, 2006, Proceedings
The primary mission of ICADL, like the Joint Conference on Digital Libraries (JCDL) and European Conference on Digital Libraries (ECDL), is to serve as a forum for exchange of new advanced te- nologies and ideas among researchers and practitioners. In addition, ICADL as a conference based in Asia is an important event not only for people in dev- oped countries but also in developing countries where there is large diversity in culture, language and development. ICADL 2006received170papersubmissionsfrom23countries.Everysubm- sion was reviewed by at least three reviewers. The Program Committee selected 46 full papers and 14 short papers based on the quality and contribution to digital library research.
Digital cities III : Information technologies for social capital: Cross-cultural Perspectives ; 3rd international digital cities workshop, Amsterdam, The Netherlands, September 18-19, 2003, Revised Selected Papers
Digital cities constitutes a multidisciplinary field of research and development, where researchers, designers and developers of communityware interact and collaborate with social scientists studying the use and effects of these kinds of infrastructures and systems in their local application context. The field is rather young. After the diffusion of ICT in the world of organizations and companies, ICT entered everyday life. And this also influenced ICT research and development. The 1998 Workshop on Communityware and Social Interaction in Kyoto was an early meeting in which this emerging field was discussed.
Differential Optical Absorption Spectroscopy : Principles and Applications
This book reviews the basics of atmospheric chemistry, radiation transport, and optical spectroscopy before detailing the principles underlying DOAS. The second part of the book describes the design and application of DOAS instruments as well as the evaluation and interpretation of spectra. The recent expansion of DOAS application to the imaging of trace gas distributions by ground, aircraft, and satellite-based instruments is also covered.
