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Novel Carrier Systems for Targeted and Controlled Drug Delivery
Presents novel carrier systems for the targeted and controlled drug delivery for the treatment of various diseases which are difficult to be treated with conventional drug delivery systems like cancer, autoimmune disorders, and emerging infectious diseases. It also reviews the origins and applications of stimuli-responsive polymer systems and polymer therapeutics such as polymer-protein and polymer-drug conjugates. The book also explores the potential applications of the parenteral route of administration for the delivery of active pharmaceutical substances with a narrow therapeutic index and poor bioavailability. Further, the book presents common routes of administration for the systemic delivery of peptides and proteins. It also examines the applications of various implantable systems in drug delivery. The book also covers the important colloidal drug delivery systems, including liposomes and niosomes and solid lipid nanoparticles, and nanostructured lipid carriers.
Novel Biotechnologies for Biocontrol Agent Enhancement and Management
This multidisciplinary group, having backgrounds in the diff- ent aspects of biotechnologies (transgenic enhancement, molecular biology, formulation, genetics, risk assessment, new technology, biochemistry, and physiology), presented highly advanced lectures during the 10-day-ASI, in order to allow students to improve their capability to enhance and manage - ological control agents. This approach will allow ASI attendees to bring new ideas, new approaches, or new methodologies coming from different ?elds of application to their own ?eld of expertise.
Novel algorithms and techniques In telecommunications, automation and industrial electronics
Novel Algorithms and Techniques in Telecommunications, Automation and Industrial Electronics includes a set of rigorously reviewed world-class manuscripts addressing and detailing state-of-the-art research projects in the areas of Industrial Electronics, Technology & Automation, Telecommunications and Networking.
Notions of Convexity
The first two chapters of this book are devoted to convexity in the classical sense, for functions of one and several real variables respectively. This gives a background for the study in the following chapters of related notions which occur in the theory of linear partial differential equations and complex analysis such as (pluri-)subharmonic functions, pseudoconvex sets, and sets which are convex for supports or singular supports with respect to a differential operator. In addition, the convexity conditions which are relevant for local or global existence of holomorphic differential equations are discussed, leading up to Trépreau’s theorem on sufficiency of condition (capital Greek letter Psi) for microlocal solvability in the analytic category.
Notes on Set Theory
This is introduction to axiomatic set theory, viewed both as a foundation of mathematics and as a branch of mathematics with its own subject matter, basic results, open problems.
Notes on Coxeter Transformations and the McKay Correspondence
One of the beautiful results in the representation theory of the finite groups is McKay's theorem on a correspondence between representations of the binary polyhedral group of SU(2) and vertices of an extended simply-laced Dynkin diagram. The Coxeter transformation is the main tool in the proof of the McKay correspondence, and is closely interrelated with the Cartan matrix and Poincaré series. The Coxeter functors constructed by Bernstein, Gelfand and Ponomarev plays a distinguished role in the representation theory of quivers.
Notch Signaling in Embryology and Cancer : Notch Signaling in Cancer
This thoroughly revised second edition is an up-to-date overview of the current knowledge of Notch and Notch signaling in embryology and cancer. It discusses this topic from Notch’s role in the development of the embryo to the Notch signaling pathway’s role in the development of a number of cancers, including breast cancer, malignant melanoma, Non-melanoma skin cancer, intestinal cancer and others. In the years since the previous edition, there have been numerous developments and insights within this rapidly moving field, making this new edition urgently needed. This volume also features discussions of current insights on Notch’s role in senescence, the regulation of Notch signaling by microRNAs, Notch’s role in the microbiome, diet and its influence on Notch signaling and more.
Nostalgia and Hope : Intersections between Politics of Culture, Welfare, and Migration in Europe
This book shows how the politics of migration affect community building in the 21st century, drawing on both retrogressive and progressive forms of mobilization. It elaborates theoretically and shows empirically how the two master frames of nostalgia and hope are used in local, national and transnational settings, in and outside conventional forms of doing politics.
Norwegian Shipping in the 20th Century : Norway's Successful Navigation of the World's Most Global Industry
This open access book discusses how Norwegian shipping companies played a crucial role in global shipping markets in the 20th century, at times transporting more than ten per cent of world seaborne trade. Chapters explore how Norway managed to remain competitive, despite being a high labour-cost country in an industry with global competition. Among the features that are emphasised are market developments, business strategies and political decisions The Norwegian experience was shaped by the main breaking points in 20th century world history, such as the two world wars, and by long-term trends, such as globalization and liberalization. The shipping companies introduced technological and organizational innovations to build or maintain a competitive advantage in a rapidly changing world. The growing importance of offshore petroleum exploration in the North Sea from the 1970s was both a threat and an opportunity to the shipping companies. By adapting both business strategies and the political regime to the new circumstances, the Norwegian shipping sector managed to maintain a leading position internationally.
Northern Lights on Civic and Citizenship Education : A Cross-national Comparison of Nordic Data from ICCS
This book presents an in depth analysis of data from ICCS. An international group of scholars critically address the state of civic and citizenship education in the four Nordic countries that participated in the IEA International Civic and Citizenship Education Study (ICCS) in 2009 and 2016. The findings are of particular relevance to educators at all levels, from school education through to teacher education.
Northeast Asia : Ripe for Integration?
Can regional mechanisms better institutionalize the increasing complexity of economic and security ties among the countries in Northeast Asia? As the international state system undergoes dramatic changes in both security and economic relations in the wake of the end of the Cold War, the Asian financial crisis, and the attack of 9/11, this question is now at the forefront of the minds of both academics and policymakers. Still, little research has been done to integrate the analysis of security and economic analysis of changes in the region within a broader context that will give us theoretically-informed policy insights. Against this backdrop, this book investigates the origins and evolution of Northeast Asia's new institutional architecture in trade, finance, and security from both a theoretical and empirical perspective.
Normal Development of Voice in Children : Advances in Evidence-Based Standards
With updated acoustical measures of voice profiles (phonetograms, the audiogram of the voice) and the fundamental frequency of the tone range, new standards have been reached . In particular, the comparison to normal pediatric and hormonal development highlights the statistical scientific validity of voice parameters. The relation to hormones and the predictive values for voice development open new and interesting perspectives for experts. This book offers valuable insight into acoustical, physiological and biological measures that compare boys and girls and are based on prospective and stratified studies.
Nordic Mediation Research
Presents twelve unique studies on mediation from researchers in Denmark, Finland, Norway and Sweden, respectively. Each study highlights important aspects of mediation, including the role of children in family mediation, the evolution and ambivalent application of restorative justice in the Nordic countries, the confusion of roles in court-connected mediation, and the challenges in dispute systems.
Nordic consumer culture : State, market and consumers
Unpacking the complexities of Nordic consumer culture, this edited collection responds to the growing interest in regionalism within consumer research and marketing. By taking a closer look at the interaction between the state and the market in Nordic countries, The authors examine how consumer behaviour is impacted by the region’s unique context. Important elements of Nordic culture are explored, Such as its underlying element of mythology and the concept of ‘hygge,’ an object of global consumption.
Non-Vitamin K Antagonist Oral Anticoagulants : A Concise Guide
An essential guide to the medical treatment of thrombosis and presents core principles of anticoagulant therapeutics as well as drug recommendations. Written by recognized experts in the field, this concise, accessible handbook provides a unique and valuable resource in the cardiovascular field, both for those currently in training, and for those already in clinical or research practice.
Non-viral Gene Therapy: Gene Design and Delivery
The development of gene medicine based on the concept of molecular therapy has opened new medical horizons. Among the many techniques in gene medicine, gene design and delivery are especially significant in clinical applications. This book presents state-of-the-art information on non-viral gene-delivery techniques, covering a broad spectrum of disciplines that include chemistry, molecular biology, cell biology, and pharmacokinetics
Non-University Higher Education in Europe
This book represents the first-of-its-kind comprehensive discussion of the non-university higher education sector in Europe. Higher education throughout the world is facing rapid change. Despite the enormous attention devoted to that reality, this volume fills an important void. It describes and offers critical comparisons between the systems in 10 European countries. The book brings together the thinking of leading scholars on the non-university sectors in Austria, Belgium, Finland, Germany, Ireland, the Netherlands, Norway, Portugal, Spain, and the United Kingdom, with a chapter devoted to each country. National case studies are presented for the non-university sector in these countries that address issues such as historical developments, policy changes, governance structures, levels of institutional autonomy and future trends.
Nonunion of the Long Bones : Diagnosis and treatment with compression-distraction techniques
The primary purpose of this book is to discuss currently available tools for diagnosing long bone nonunions, to illustrate the means of prevention, and to specify the indications for management using compression-distraction techniques.
Non-Surgical Control of Periodontal Diseases : A Comprehensive Handbook
Designed for practicing dental clinicians and students, which includes dental hygienists, general dentists, periodontists, and students of dental hygiene and dentistry who are responsible for treating patients with a broad spectrum of periodontal diseases.
Nonstandard Analysis
The book is an introduction with emphasis on those more advanced applications in analysis which are hardly accessible by other methods. Examples of such topics are a deeper analysis of certain functionals like Hahn-Banach limits or of finitely additive measures: From the viewpoint of classical analysis these are strange objects whose mere existence is even hard to prove. From the viewpoint of nonstandard analysis, these are rather 'explicit' objects.
