Life - As a Matter of Fat : The Emerging Science of Lipidomics

Life - As a Matter of Fat : The Emerging Science of Lipidomics

Author
Ole G. Mouritsen
Publication Year
2005
Publisher
Springer
Language
English
Document Type
Book
Faculty / Subject Heading
Physics

Lipids are as important for life as proteins, sugars, and genes. The present book gives a multi-disciplinary perspective on the physics of life and the particular role played by lipids and the lipid-bilayer component of cell membranes. The book is aimed at undergraduate students and young research workers within physics, chemistry, biochemistry, molecular biology, nutrition, as well as pharmaceutical and biomedical sciences. The emphasis is on the physical properties of lipid membranes seen as soft and molecularly structured interfaces. By combining and synthesizing insights obtained from a variety of recent studies, an attempt is made to clarify what membrane structure is and how it can be quantitatively described. Furthermore, it is shown how biological function mediated by membranes is controlled by lipid membrane structure and organization on length scales ranging from the size of the individual molecule, across molecular assemblies of proteins and lipid domains in the range of nanometers, to the size of whole cells. Applications of lipids in nano-technology and biomedicine are also described.


Keywords: Physics and Astronomy / Cells / Cholesterol / Fatty acids / Lipid bilayer / Lipid membrane / Proteins / Soft interfaces