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Cell Signaling in Vascular Inflammation

Although inflammatory disease of the vascular bed of the lung is a major cause of morbidity and mortality in both adult and pediatric age groups, the importance of vascular biology to its understanding, and in developing novel therapeutics, has been overlooked. In Cell Signaling in Vascular Inflammation, leading basic and clinical researchers review the signal transduction mechanisms responsible for lung inflammation, including vascular hyperpermeability, white cell accumulation, and vascular remodeling. The authors cut across disciplines to bring together a broad-based presentation of inflammatory challenge, both in the initial phases of the inflammatory response, as well as in the more prolonged phase of genomic involvement.

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Biomarkers as targeted herbal drug discovery : A pharmacological approach to nanomedicines

Looks at the applications of biomarkers as important tools for herbal drug discovery, presenting research on phytoconstituents with advanced nanotechnological applications for healthcare benefits. Herbal drug discovery based on biomarkers is an emerging area in complementary and alternative medicine that has tremendous potential in healthcare. Conventional medications have limited efficacy and high toxicity, whereas herbal drugs are said to provide wide structural diversity that is not usually seen with conventional/synthetic drug molecules. Recognition of various herbal constituents, such as terpenoids, fatty acids, flavonoids and steroids, are well explored in the management and treatment of various disorders in this volume. These agents target various biomarkers such as nitric oxide (NO), cytokines, chemokines, adhesion molecules, NF- kβ, lipoxygenase (LOX), and arachidonic acid. Reviews the literature on inflammatory biomarkers in the treatment of diseases Looks at the development of herbal drug discovery based on biomarkers Explores emerging concepts of nanomedicines for herbal drug delivery Takes an interdisciplinary approach, with application to disciplines related to medical, pharmaceutical, biotechnological, Ayurvedic, Unani and biomedical engineering fields

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Advanced concepts in fluorescence sensing ; Part A : Small molecule sensing

"This volume incorporates authoritative small molecule analytical fluorescence sensing reviews specialized enough to be attractive to professional researchers, yet also appealing to the wider audience of scientists in related disciplines of fluorescence. Advanced Concepts in Fluorescence Sensing Part A: Small Molecule Sensing is an essential reference for any lab working in the analytical fluorescence sensing field. All academics, bench scientists, and industry professionals wishing to take advantage of the latest and greatest in the continuously emerging field of fluorescence sensing will find it an invaluable resource. Advanced Concepts in Fluorescence Sensing Part A: Small Molecule Sensing topics include: Probes for Anion and Cation Sensing / Fluorescent Carbon Dioxide Indicators / Fluorescent Redox-Switchable Devices / PET based Fluorescence Sensors / Oxygen Sensing / Fluorescence Sensing using Charge Transfer Probes / Fluorescence-based Nitric Oxide Detection "

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