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Lifestyle nutrition eating for good health by lowering the risk of chronic diseases
Provides physicians with an evidence-based introduction to nutrition science with a practical emphasis on how to apply this information to improve the health of their patients and enhance their own lives. From nutrition and atherosclerosis to erectile dysfunction and chronic kidney disease to osteoporosis, this comprehensive guide covers a wide range of conditions influenced by diet. It delves into specialized areas, such as nutrition for physically active people to the elderly, ensuring relevance for diverse patient populations. The reader will find detailed analysis of the Dietary Guidelines for Americans 2020–2025 and their applications and strategies for adopting healthy plant-based diets, such as Mediterranean, DASH, and vegan.
Les thérapies ciblées = Targeted therapies
We are at the start of the development of new therapeutic classes, directed against new molecular targets (EGFR, VEGF, IGFR, Rank, etc.) Several diseases such as kidney, colon or breast cancer, GIST, have a natural history now modified thanks to these therapies. This practical book takes stock of the current use of these molecules.
Le Cancer du rein = Kidney cancer
Localized tumors are discovered at an earlier stage. The concept of active surveillance emerges. Minimally invasive treatments such as cryotherapy or radiofrequency for selected cases are now available. The indications for elective open partial nephrectomy are expanding and laparoscopic and then robotic partial nephrectomy are being evaluated.
Complement and Kidney Disease
It is evident that a defective or deregulated complement system results in kidney diseases. An important role of complement effector and regulatory proteins in pathological settings of the kidney has been demonstrated. A large panel of distinct human kidney diseases is caused by defective complement control. Genetic analyses have identified mutations in complement regulators that are associated with these diseases. Mutations have been identified in the fluid phase alternative pathway regulator Factor H and the membrane regulator Membrane Cofactor Protein MCP (CD46). The functional characterization of the mutant proteins allows to define the pathophysiological events on a molecular level. These new concepts and data on disease mechanisms allowed establishing new diagnostic and promising therapeutic approaches for several human kidney diseases. Molecular biology, clinics and therapy are discussed in this volume.
Clinical Nephrotoxins: Renal Injury from Drugs and Chemicals
Clinical Nephrotoxins: Renal Injury from Drugs and Chemicals is a comprehensive handbook on all aspects of adverse effects by drugs and chemical substances on the kidneys.
Clinical Management of Renal Tumors
Clinical Management of Renal Tumors provides an in-depth review of the data relating to the management of renal tumors as well as an updated description regarding pathologic and molecular classification of renal tumors.
Calcium and Phosphate Metabolism Management in Chronic Renal Disease
Calcium and Phosphate Metabolism Management in Chronic Renal Diseases provides an overview of the state-of-the-art clinical and basic science aspects of abnormal calcium and phosphate metabolism and its management.
Anti-Neutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis
Covers all aspects of Anti-Neutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis (AAV). The expression refers to a group of diseases, characterized by destruction and inflammation of small vessels. The clinical signs vary and affect several organs, such as the kidney, lung, skin, nervous system and others. presents recently acquired knowledge on pathogenesis, diagnosis, and therapy with the aim of promoting a more holistic approach to these conditions. AAVs are systemic autoimmune diseases of unknown cause that affect small (to medium) sized blood vessels. They include granulomatosis with polyangiitis (formerly Wegener's granulomatosis), microscopic polyangiitis, and eosinophilic granulomatosis with polyangiitis (formerly Churg–Strauss syndrome).
Antidiabetic medicinal plants and herbal treatments
Diabetes is a chronic condition associated with metabolic disorder. Persons suffering from diabetes have shown accelerated levels of blood sugar which often harms the heart, blood vessels, eyes, kidneys, and nerves. Over the past few decades, the prevalence of diabetes has been progressively increasing. Synthetic drugs are used to treat diabetic patients to help control the disorder, but it is shown that numerous medicinal plants and herbal drugs are widely used in several traditional systems of medicine to prevent and treat diabetes. They are reported to produce beneficial effects in combating diabetes and alleviating diabetes-related complications. These plants contain phtyonutrients and phytoconstituents demonstrating protective or disease preventive properties. In many developing countries, herbal drugs are recommended by traditional practitioners for diabetes treatment because the use of synthetic drugs is not affordable.
Acquired Cystic Disease of the Kidney and Renal Cell Carcinoma : Complication of Long-Term Dialysis
I have been involved in the treatment of chronic renal insuf? new and unexpected pathological conditions have also appeared as complications of long-term dialysis. One of these involves polycystic changes and their malignant transformation in diseased kidneys. Since I have studied these polycystic changes and their malignant transformation for many years, I decided to compile the results of my work in a book. Such conditions of diseased kidneys pose serious problems, particularly in Japan, where renal transplantation is performed very infrequently compared with other countries, and a large number of patients are managed by dialysis over a long period.
Bone Morphogenetic Proteins : From Local to Systemic Therapeutics
Tissue engineering is gaining interest as it is applied for regeneration of organs to attain their lost function. Although resorbable scaffolds and progenitor cell types are required principles to engineer a functional tissue locally, the inductive signal is a prerequisite to trigger the growth and differentiation of responding cells in space and time. Bone morphogenetic proteins (BMPs), also called growth and differentiation factors (GDFs), originally identified from bone have been successfully used to regenerate the bone in humans. Most recent preclinical data suggests that BMPs have a potential to provide protection against inflammation and fibrosis in acute and chronic injury of parenchymal tissues when applied systemically to sustain the function of kidney and liver. The application of BMPs from a local to systemic utility is a rapidly growing field, gaining interest among researchers and biotech entrepreneurs.
