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Thyroid Gland Disorders
Thyroid Gland and its Role In Human body. PHYSIOLOGIC ANATOMY OF THE THYROID GLAND: The thyroid gland, located immediately below the larynx on each side of and anterior to the trachea, is one of the largest endocrine glands. The thyroid secretes two major metabolic hormones thyroxine and triiodothyronine, commonly called T4 and T3, respectively. the thyroid gland is composed of large numbers of closed follicles that are filled with a secretory substance called colloid and lined with cuboidal epithelial cells that secrete into the interior of the follicles. The major constituent of colloid is the large glycoprotein thyroglobulin, which contains the thyroid hormones. The thyroid gland also contains C cells that secrete calcitonin, a hormone that contributes to regulation of plasma calcium ion concentration.
Taurine 6
Taurine (2-aminoethanesulfonic acid) is an enigmatic compound abounding in animal tissues. It is present at relatively high concentrations in all electrically excitable tissues such as the brain, sensory organs, the heart, and in certain endocrine glands. Some of its physiological functions are already established.
Parathyroid Allotransplantation
The parathyroid glands are four nodular structures, typically located on the dorsum of the thyroid at each of its four poles. These glands monitor the serum calcium level and secrete parathyroid hormone (PTH) when it is low.[81] PTH is essential for maintaining calcium homeostasis. Thus, dysregulation of this hormone can lead to various pathologies
Hormone balance for dummies
Hormones are your body's chemical "messengers," the regulators of essential functions like metabolism, reproduction, mood, and growth. But, in our 24/7, hyper-connected modern world, many of us increasingly find ourselves in situations of chronic stress that can imbalance or disrupt our bodies' natural hormonal balance. In Hormone Balance For Dummies, renowned hormone health coach Isabella Mainwaring delivers an accessible and exciting new take on hormonal imbalance. You'll discover why hormone balance is so important for you and contributes to everything from the maintenance of a healthy weight to fertility, mental wellness, and overall health. The author goes beyond diet and lifestyle to offer practical nervous system regulation tips and dive deep on available treatment options for hormonal imbalance
Aromatase Inhibitors
Many breast tumours are dependent upon oestrogen for their development and continued growth. Over the last 25 years hormone therapy has progressed from the irreversible destruction of endocrine glands to the use of drugs that reversibly suppress oestrogen synthesis or action. The inhibition of oestrogen synthesis is most readily achieved by inhibiting the final step in the pathway of oestrogen biosynthesis, the reaction which transforms androgens into oestrogens by creating an aromatic ring in the steroid molecule (hence the enzyme's trivial name, aromatase). Whereas the first aromatase inhibitors to be used therapeutically could be shown to produce drug-induced inhibition of the enzyme and therapeutic benefits in patients with breast cancer, they were not particularly potent and lacked specificity. However, second-generation drugs were developed and most recently third-generation inhibitors have evolved which possess remarkable specificity and potency. Initial results from clinical trials suggest that these agents will become the cornerstones of future endocrine therapy.
Aromatase Inhibitors
Many breast tumours are dependent upon oestrogen for their development and continued growth. Over the last 25 years hormone therapy has progressed from the irreversible destruction of endocrine glands to the use of drugs that reversibly suppress oestrogen synthesis or action. The inhibition of oestrogen synthesis is most readily achieved by inhibiting the final step in the pathway of oestrogen biosynthesis, the reaction which transforms androgens into oestrogens by creating an aromatic ring in the steroid molecule (hence the enzyme's trivial name, aromatase). Whereas the first aromatase inhibitors to be used therapeutically could be shown to produce drug-induced inhibition of the enzyme and therapeutic benefits in patients with breast cancer, they were not particularly potent and lacked specificity. However, second-generation drugs were developed and most recently third-generation inhibitors have evolved which possess remarkable specificity and potency. Initial results from clinical trials suggest that these agents will become the cornerstones of future endocrine therapy.
