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Marine Natural Products
The search for marine natural products is well-known for colorful pictures of exotic creatures which, after having been found to contain the cure for cancer, disappear into the depths, never to be seen again, or for accounts of scuba-diving chemists in waters alive with poisonous sea snakes - in short, the sort of sensational stuff that even nonchemists find interesting. That sort of thing will not be found in this book.
Chemical Genomics ; Vol.58 : Small Molecule Probes to Study Cellular Function
Chemical genomics is a highly interdisciplinary and very exciting field of research both in academics and in the life sciences industry.Various aspects of the interface between chemistry and biology are covered in this volume, such as chemogenomics efforts in the pharmaceutical industry, diversity-oriented synthesis, chemogenomic approaches to the study of cell function, screening technologies, and natural products as tools in chemical biology.
Bioactive Molecules and Medicinal Plants
Use of medicinal plants is as old as human civilization and continuous efforts are being made to improve medicinal plants or produce their products in high amounts through various technologies. About 200,000 natural products of plant origin are known and many more are being identifed from higher plants and microorganisms. Some plant-based drugs have been used for centuries and there is no alternative medicine for many drugs, such as cardiac glycosides. However, natural products research was sidelined to pave the way for com- natorial chemistry, which was expected to produce large numbers of synthetic compounds for high-throughput screening (HTS). This line of work has failed to deliver desirable results. Moreover, it is not possible for all pharmaceutical companies and institutions to adopt costly HTS technology. Therefore, medi- nal plants and their bioactive molecules are always in demand and are a central point of research. While planning this book, we endeavored to incorporate - ticles that cover the entire gamut of current medicinal plants research.
Bioactive Marine Natural Products
Bioactive Marine Natural Products is the first book available that covers all aspects of bioactive marine natural products. It fills the void in the literature for bioactive marine natural products. The book covers various aspects of marine natural products and it is hoped that all the major classes of bioactive compounds are included. Different classes of marine organisms and the separation and isolation techniques are discussed. The chemistry and biology of marine toxins, peptides, alkaloids, nucleosides and prostanoids are discussed in detail. Biological, toxicological and clinical evaluations are also dealt with to ensure that the book may be adopted at any stage by any practicing organic chemist or biologist, working in academia or in R&D divisions of pharmaceutical companies. Each chapter in the book includes an abstract to highlight the major points discussed in the text and concluding remarks are given. References to books, monographs, review articles and original papers are provided at the end of each chapter.
Bioactive Heterocyles I
Bioactive Heterocycles I is a continuation of critical accounts about heterocyclic compounds within the series Topics in Heterocyclic Chemistry. The present volume provides comprehensive reviews of the chemistry and bioactivity of selected groups of heterocycles and natural products. … Overall, this book covers in detail several classes of bioactive heterocyclic compounds including selected natural products. The focus is on the most recent advances, and the clarity of the presentation is very good. It should be of interest to individuals interested in the discovery and synthesis of bioactive small molecules, including research scientists in academia and industry.
