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Applications of Mass Spectrometry in Life Safety
MS is continuously developing as one of the most re- able analytical method for elucidating the structure of molecules originating from various biological matrices. The potential of MS for high-sensitive structural a- lyses became unsurpassable after the introduction of electrospray (ESI) and matrix assisted laser/desorption ionization (MALDI) methods, on one hand, and the pos- bility to deduce in detail unknown biopolymer structures by highly accurate mo- cular mass measurement followed by sequencing using dissociation techniques based on multiple stage MS, on the other.
Analysis file of drug-induced lung injury : expert opinion for analysis of big data
Describes the pathologic conditions of drug-induced lung injuries, monitoring strategies, and guides on how to interpret the evidence. It also dives into particular drugs that caused the disorder, such as EGFR inhibitors, anti-EGFR antibodies, mTOR inhibitors, proteasome inhibitors, immune checkpoint inhibitors, neoangiogenesis inhibitors, and other molecular targeted drugs. It outlines the analysis and interpretation of the post-marketing survey on surveillance of each drug for inducing pulmonary lesions presenting diffuse haziness. The data and analysis from this survey are valuable since a guideline is yet to be established due to limited clinical evidence and cases. As new drugs are developed, establishing treatment and event management is crucial.
Advances in pharmacokinetics and pharmacodynamics
Provides a concise overview of recent advances in Pharmacokinetics (PK) and Pharmacodynamics (PD). The pharmacokinetics section covers the state of the art in Physiologically Based Pharmacokinetic (PBPK) modeling (Chapter 1) as well as the assessment of food effect on drug absorption using PBPK modeling (Chapter 2). Chapters 3 and 4 describe the recent development of Physiologically Based Finite Time Pharmacokinetic (PBFTPK) models and their applications to pharmacokinetic data. The pharmacodynamics section focuses on PK/PD modeling. Chapter 5 provides an overview of PK/PD modeling and simulation in clinical practice and studies. Chapter 6 deals with the subject/physiology variability issue encountered in PK/PD studies, while Chapter 7 reviews the influence of clinical pharmacology in the modernization of drug development and regulation. This book is an essential reference for pharmaceutical scientists.
Magazines, Tourism, and Nation-Building in Mexico
This book discusses the relationship between periodicals, tourism, and nation-building in Mexico. It enquires into how magazines, a staple form of the promotional apparatus of tourism since its inception, articulated an imaginative geography of Mexico at a time when that industry became a critical means of economic recovery and political stability after the Revolution. Notwithstanding their vogue, popularity, reach, and close affiliations to commerce and state over several decades, magazines have not received any sustained critical attention in the scholarship on that period.
Justice in extreme cases: criminal law theory meets international criminal law
Shows how to use moral theory to challenge and improve ICL, and how extreme cases can challenge and improve criminal law theory. It will appeal to scholars and jurists in ICL, as well as scholars of criminal law theory or legal philosophy.
Common Law, Civil Law, and Colonial Law : Essays in Comparative Legal History from the Twelfth to the Twentieth Centuries
This volume is a selection of essays taken from the excellent range of papers presented at the British Legal History Conference hosted by the Institute for Legal and Constitutional Research at the University of St Andrews, 10-13 July 2019. The theme of the conference gives this book its title: 'comparative legal history'. The topic came easily to the organisers because of their association with the St Andrews-based European Research Council Advanced grant project 'Civil law, common law, customary law: consonance, divergence and transformation in Western Europe from the late eleventh to the thirteenth centuries'.
Building the judiciary : law, courts, and the politics of institutional development
Building the Judiciary uncovers the causes and consequences of judicial institution-building in the United States from the commencement of the new government in 1789 through the close of the twentieth century.Explaining why and how the federal judiciary became an independent, autonomous, and powerful political institution.
Buddhism and comparative constitutional law
The first comprehensive account of the entanglements of Buddhism and constitutional law,The authors also highlight the important ways in which Buddhist actors have (re)conceived Western liberal ideals such as constitutionalism, rule of law, and secularism.
Big Data and Global Trade Law
Explores the relevance of global trade law for data, big data and cross-border data flows. Contributing authors from different disciplines including law, economics and political science analyze developments at the World Trade Organization and in preferential trade venues by asking what future-oriented models for data governance are available and viable in the area of trade law and policy. The collection paints the broad picture of the interaction between digital technologies and trade regulation as well as provides in-depth analyses of critical to the data-driven economy issues, such as privacy and AI, and different countries' perspectives.
Artificial intelligence and legal analytics : new tools for law practice in the digital age
The field of artificial intelligence (AI) and the law is on the cusp of a revolution. This book - designed to explain computational processes to non-programmers - describes how text analytic programs will change the practice of law, specifically by connecting computational models of legal reasoning directly with legal text.
Artificial Intelligence and International Economic Law : Disruption, Regulation, and Reconfiguration
This book was finalized while countries around the world were still confronting a global public health crisis caused by the COVID-19 pandemic. Many came to rely on digital services as an infrastructure for social interaction and professional endeavors, including academic and educational work. The pandemic seems to have precipitated a further shift towards digital technologies and artificial intelligence. It is our hope that this book will contribute to an informed discussion about the relevance of and implications for international economic law beyond the pandemic"
An introduction to law
this book addresses the ways in which rules and the structures of law respond to and impact upon changes in economic and political life. The title has been extensively updated and explores recent high profile developments such as the Civil Partnership Act 2005 and the Racial and Religious Hatred Bill.
An Introduction to international criminal law and Procedure
Offers readers comprehensive coverage and a high level of academic rigour while maintaining its signature accessible and engaging style. Introducing the readers to the fundamental concepts of international criminal law, as well as the domestic and international institutions that enforce that law, this book engages with critical questions, political and moral challenges, and alternatives to international justice.
Machine Learning Refined : Foundations, Algorithms, and Applications
Provides students with the fundamental knowledge and practical tools needed to conduct research and build data-driven products. The authors prioritize geometric intuition and algorithmic thinking, and include detail on all the essential mathematical prerequisites, to offer a fresh and accessible way to learn. Practical applications are emphasized, with examples from disciplines including computer vision, natural language processing, economics, neuroscience, recommender systems, physics, and biology.
Machine Learning for Audio, Image and Video Analysis : Theory and Applications
The book is organized in four parts: The first focuses on technical aspects, basic mathematical notions and elementary machine learning techniques. The second provides an extensive survey of most relevant machine learning techniques for media processing, while the third part focuses on applications and shows how techniques are applied in actual problems. The fourth part contains detailed appendices that provide notions about the main mathematical instruments used throughout the text
Competitive Programming in Python : 128 Algorithms to Develop your Coding Skills
Learn all the algorithmic techniques and programming skills you need from two experienced coaches, problem setters, and jurors for coding competitions. The authors highlight the versatility of each algorithm by considering a variety of problems and show how to implement algorithms in simple and efficient code. What to expect: * Master 128 algorithms in Python. * Discover the right way to tackle a problem and quickly implement a solution of low complexity.
Boundary Representation Modelling Techniques
Boundary representation is the principle solid modelling method used in modern CAD/CAM systems. There have been a long series of developments on which currently available systems are based, full details of which are only partially known. Ian Stroud’s thorough coverage of these developments puts this technology in perspective. Ian Stroud started working with boundary representation solid modelling in 1977. Since then he has researched and is researching a wide variety of topics in and around this field. The information in the book comes from the results of this research.
Big data analysis of nanoscience bibliometrics, patent, and funding data (2000-2019)
Presents an evaluation of nanotechnologies outputs (academic outputs and patents) and their impact from 2000-2019. The evaluation uses Elsevier’s Scopus (the largest abstract and citation database of peer-reviewed literature), SciVal (a scientific research analysis platform), Funding Institutional (a funding database), and PatentSight (a patent analysis platform). It covers four key topics regarding nanoscience research, including: 1) An overview of nano-related scholarly output, 2) Nanoscience and its contribution to basic science, 3) Nanoscience and its impact on and collaboration with industry partners, and 4) Key factors that promote the development of nanoscience.
Beyond the Worst-Case Analysis of Algorithms
There are no silver bullets in algorithm design, and no single algorithmic idea is powerful and flexible enough to solve every computational problem. Nor are there silver bullets in algorithm analysis, as the most enlightening method for analyzing an algorithm often depends on the problem and the application. However, typical algorithms courses rely almost entirely on a single analysis framework, that of worst-case analysis, wherein an algorithm is assessed by its worst performance on any input of a given size. The purpose of this book is to popularize several alternatives to worst-case analysis and their most notable algorithmic applications, from clustering to linear programming to neural network training. Forty leading researchers have contributed introductions to different facets of this field, emphasizing the most important models and results, many of which can be taught in lectures to beginning graduate students in theoretical computer science and machine learning.
Beginning Ubuntu Linux
Beginning Ubuntu Linux, the award–winning and best–selling Ubuntu book for beginners, is now in its third edition, presenting readers with an up–to–the–minute introduction to the world of Linux and the open source community. A detailed overview of Ubuntu's installation and configuration process encourages you to take the plunge and switch to Linux, and from there you'll learn how to wield total control over your newly installed operating system. Guided through the most commonly desired tasks such as printer configuration, listening to audio CDs and MP3s, watching movies, performing office and Internet–related tasks, as well as general system maintenance matters, authors Keir Thomas and Jaime Sicam will soon have you using and enjoying Ubuntu Linux and never looking back.
