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Manufacturing of Pharmaceutical Proteins: From Technology to Economy

Manufacturing of Pharmaceutical Proteins: From Technology to Economy, renowned chemical engineer Dr. Stefan Behme delivers a comprehensive text covering all aspects of biopharmaceutical manufacturing, including legal and regulatory considerations, production facility design, quality assurance, supply chain management, emerging market regulations, and cost control.

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Beyond global food supply chains : Crisis, disruption, regeneration

Through a set of incisive essays, this incredibly timely book shows how much the COVID-19 pandemic has exposed both vulnerabilities and opportunities - for (racial) capitalism and its discontents alike to intervene in food supply chains. A most welcome publication! This book takes the upheaval of the global COVID-19 pandemic as a springboard from which to interrogate a larger set of structural, environmental and political fault lines running through the global food system. In a context in which disruptions to the production, distribution, and consumption of food are figured as exceptions to the smooth, just-in-time efficiencies of global supply chains, these essays reveal the global food system as one that is inherently disruptive of human lives and flourishing, and of relationships between people, places, and environments. The pandemic thus represents a particular, acute moment of disruption, offering a lens on a deeper, longer set of systemic processes, and shining new light on transformational possibilities.

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Machine Learning and Probabilistic Graphical Models for Decision Support Systems

Presents recent advancements in research, a review of new methods and techniques, and applications in decision support systems (DSS) with Machine Learning and Probabilistic Graphical Models, which are very effective techniques in gaining knowledge from Big Data and in interpreting decisions. It explores Bayesian network learning, Control Chart, Reinforcement Learning for multicriteria DSS, Anomaly Detection in Smart Manufacturing with Federated Learning, DSS in healthcare, DSS for supply chain management, etc. Researchers and practitioners alike will benefit from this book to enhance the understanding of machine learning, Probabilistic Graphical Models, and their uses in DSS in the context of decision making with uncertainty. The real-world case studies in various fields with guidance and recommendations for the practical applications of these studies are introduced in each chapter.

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Knowledge and Skill Chains in Engineering and Manufacturing : Information Infrastructure in the Era of Global Communications

Explores knowledge and skill chains in engineering and manufacturing in the age of global communications. Information infrastructure involves a range of activities from product planning, engineering, and manufacturing trough transportation, marketing, and repair/upgrade to returns and recycling/disposal. Distinct from the traditional engineering database, life-cycle support information has its own characteristic requirements, -- flexible extensibility, distributed architecture, multiple viewpoints, long-time archiving, and product usage information. Several authors address the architecture of the information infrastructure, its services and its requirements. Other papers focus on the knowledge and skill chains that develop in a variety of situations: the supply chain, the factory floor, the man-system interaction, etc. For each of these, state-of-the-art and state-of-research scenarios for various industrial sectors address both engineering and operations requirements in the current socio-economic environment.

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Agent-based Supply Network Event Management

Supply Chain Event Management (SCEM)" is one of the major topics in application-oriented Supply Chain Management. However, many solutions lack conceptual precision and currently available client-server SCEM-systems are ill-suited for complex supply networks in today's business environment,In this book a thorough analysis of the event management problem domain is the starting point to develop a generic agent-based approach to Supply Network Event Management. The concept is illustrated with prototypical implementations and assessed in a multi-dimensional evaluation of potential benefits. The main focus lies on practical issues of event management (e.g. semantic interoperability) and economic benefits to be achieved with agent technology in this state-of-the-art problem domain.

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Material Flow Management : Improving Cost Efficiency and Environmental Performance

The implementation of material flow management offers enterprises a high potential for realizing new economic competitive advantages. The eco-efficient optimization of material flows aims at reducing costs while simultaneously achieving long-term sustainability with regard to ecological and societal aspects. Knowledge of existing methods and the latest trends is a key prerequisite for successfully implementing, refining and disseminating material flow management approaches.

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Mass Customization : Challenges and Solutions

Mass Customization: Challenges and Solutions defines the parameters of the emerging business strategy, mass customization. The book will cover the main categories of the area with a systematic examination of the following themes: manufacturing systems and mass customization, supply chain management and mass customization, and information systems and mass customization.

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Marketing and the Customer Value Chain : Integrating Marketing and Supply Chain Management

Offers a systemic approach to the integration of marketing and supply chain management. It examines the strategic connections and disconnections between supply chain and operations management and marketing by focusing on the factors that constitute the extended marketing mix, including product, price, promotion, people, and processes.

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Managing product life cycle in a supply Chain Context : A prescription based on empirical research

The aim of this book is to provide a better understanding with as to how to coordinate and improve decisions about product life cycle, process and supply chain design to improve new product development.

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Managing Closed-Loop Supply Chains

Introduction Closing supply chains refers to taking care of items once they are no longer desired or can no longer be used by their user. Smart management of closed-loop supply chains means profitable recovery of value from these items (products, functional components, materials or packaging). The company closing the supply chain may be the original equipment manuf- turer (OEM), a distribution partner or a third party not involved in the f- ward distribution. In recent years, the management of closed-loop supply chains has gained importance because of increased legislation on producer respon- bility, requiring companies to take back products from customers and to organize for proper recovery and disposal. This legislation is partially due to increased awareness of environmental issues. However, smart com- nies have also understood that returned products often contain lots of value to be recovered. They manage closed-loop supply chains simply because it is a profitable business proposition.

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Managing Business Interfaces : Marketing and Engineering Issues in the Supply Chain and Internet Domains

Within companies and organizations there is an increased emphasis on making different functional areas work together seamlessly. These developments have led to an increased emphasis on research and practice in business that integrate the functional areas within and between business entities. The research community has recognized the importance of addressing these different, and often conflicting, business perspectives. This has led to research streams that address issues characterizing the domain of business interfaces. These include the benefits of coordination, new product development, product portfolio management, supply chain coordination, and partnerships and collaboration in the Internet space.

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Low-Cost Country Sourcing : Trends and Implications

Globalization has induced immense cost pressure in most industries. In combination with the economic downturn after the turn of the century, companies are increasingly looking for new ways of reducing costs and increasing shareholder value. From this perspective, low-cost country sourcing has proved to be an effective means to realize cost-saving targets. Although many external key success factors have been identified, relatively little is known about intra-firm factors that can influence the outcome of low-cost country sourcing initiatives.

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Logistics Systems : Design and Optimization

In a context of global competition, the optimization of logistics systems is inescapable. LOGISTICS SYSTEMS: Design and Optimization falls within this perspective and presents twelve chapters that well illustrate the variety and the complexity of logistics activities. Each chapter is written by recognized researchers who have been commissioned to survey a specific topic or emerging area of logistics. The first chapter, by Riopel, Langevin, and Campbell, develops a framework for the entire book. It classifies logistics decisions and highlights the relevant linkages to logistics decisions. The intricacy of these linkages demonstrates how thoroughly the decisions are interrelated and underscores the complexity of managing logistics activities. Each of the following chapters focus on quantitative methods for the design and optimization of logistics systems.

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Lean Management for Small and Medium Sized Enterprises : Adapting Operations to Changing Business Environment

Provides a step-by-step guide to implementing lean at SMEs using an approach that has been tested and fine-tuned at over a hundred organizations across India, South East Asia and the Middle East. The book approaches Lean through an implementation project cycle flow and enables the reader to understand the imperative for Lean, how to diagnose current operations, how to plan and deploy Lean and shows a path for long-term sustenance.

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Just-in-Time Scheduling : Models and Algorithms for Computer and Manufacturing Systems

As the field of Supply Chain Management has matured, maintaining the precise flow of goods to maintain schedules (hence, minimizing inventories) on a just-in-time basis still remains as a major challenge. This problem or challenge has resulted in a fair amount of quantitative research in the area, producing an array of models and algorithms to help ensure the precise flow of components and final products into inventories to meet just-in-time requirements.The scheduling models and algorithms presented and illustrated in the book will be done so in the context of extensive use of computer systems in a "real time context.

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Characteristic based planning with mySAP SCM™ : Scenarios, processes, and functions

Characteristics are used in SAP as attributes, e.g. to specify the configuration of products or the properties of batches. In many industries – engineering, automotive, mill, pharmaceutical and foods to name the most typical – supply chain planning has to consider these characteristics. APO offers many different functionalities for planning with characteristics, where each of the functionalities has some prerequisites and incompatibilities. This book offers help and advice for the basic design of the implementation by explaining the processes and scenarios (process chains) for planning with characteristics, the functionalities for planning with characteristics in APO including their prerequisites and incompatibilities and the entities, dependencies and system configuration determinants for planning with characteristics in R/3 and APO. This book is based on the releases R/3 4.7 and mySAP SCM 4.1.

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Building supply chain excellence in emerging economies

How can we manage supply chains well in emerging economies, coordinate information flows with multiple partners, tackle challenges such as unexpected disruptions, diversify the risks and increase flexibilities, ​are the topics and issues of the book.

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Analysis and Algorithms for Service Parts Supply Chains

Services requiring parts has become a $1.5 trillion business annually worldwide, creating a tremendous incentive to manage the logistics of these parts efficiently by making planning and operational decisions in a rational and rigorous manner. This book provides a broad overview of modeling approaches and solution methodologies for addressing service parts inventory problems found in high-powered technology and aerospace applications. The focus in this work is on the management of high cost, low demand rate service parts found in multi-echelon settings. This unique book, with its breadth of topics and mathematical treatment, begins by first demonstrating the optimality of an order-up-to policy [or (s-1,s)] in certain environments. This policy is used in the real world and studied throughout the text. The fundamental mathematical building blocks for modeling and solving applications of stochastic process and optimization techniques to service parts management problems are summarized extensively. A wide range of exact and approximate mathematical models of multi-echelon systems is developed and used in practice to estimate future inventory investment and part repair requirements.

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Agricultural value chains in India : Ensuring competitiveness, inclusiveness, sustainability, scalability, and improved finance

This book provides a clear holistic conceptual framework of CISS-F (competitiveness, inclusiveness, sustainability, scalability and access to finance) to analyse the efficiency of value chains of high value agricultural commodities in India. It is based on the understanding that agriculture is an integrated system that connects farming with logistics, processing and marketing. Farmer’s welfare being central to any agricultural policy makes it very pertinent to study how a value chain works and can be strengthened further to realize this policy goal.

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Advanced Trends in ICT for Innovative Business Management

Contains a collection of scientific chapters addressing the emerging trends in IT and telecommunications, as well as the issues that accompany them in business. It addresses issues in cyber applications, ICT solutions and innovative cyber know-how, and demonstrates how high-tech IT communications resources can be used to improve business production, sales and service strategies, supply chains and logistics.

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